KEGG   ENZYME: 6.2.1.27Help
Entry
EC 6.2.1.27                 Enzyme                                 

Name
4-hydroxybenzoate---CoA ligase;
4-hydroxybenzoate-CoA synthetase;
4-hydroxybenzoate---coenzyme A ligase (AMP-forming);
4-hydroxybenzoyl coenzyme A synthetase;
4-hydroxybenzoyl-CoA ligase
Class
Ligases;
Forming carbon-sulfur bonds;
Acid-thiol ligases
BRITE hierarchy
Sysname
4-hydroxybenzoate:CoA ligase (AMP-forming)
Reaction(IUBMB)
ATP + 4-hydroxybenzoate + CoA = AMP + diphosphate + 4-hydroxybenzoyl-CoA [RN:R01300]
Reaction(KEGG)
Substrate
ATP [CPD:C00002];
4-hydroxybenzoate [CPD:C00156];
CoA [CPD:C00010]
Product
AMP [CPD:C00020];
diphosphate [CPD:C00013];
4-hydroxybenzoyl-CoA [CPD:C02949]
History
EC 6.2.1.27 created 1992
Pathway
Benzoate degradation
Aminobenzoate degradation
Metabolic pathways
Microbial metabolism in diverse environments
Orthology
K04105  
4-hydroxybenzoate-CoA ligase
Genes
BJA: 
BJU: 
BRA: 
BBT: 
BRS: 
AOL: 
RPA: 
RPA0669(hbaA)
RPB: 
RPC: 
RPD: 
RPE: 
RPT: 
RPX: 
SIL: 
SPO3697(badA-1)
JAN: 
MAG: 
 » show all
Taxonomy
Reference
1  [PMID:2914844]
  Authors
Merkel SM, Eberhard AE, Gibson J, Harwood CS.
  Title
Involvement of coenzyme A thioesters in anaerobic metabolism of 4-hydroxybenzoate by Rhodopseudomonas palustris.
  Journal
J. Bacteriol. 171 (1989) 1-7.
  Organism
Rhodopseudomonas palustris
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
UM-BBD (Biocatalysis/Biodegradation Database): 
BRENDA, the Enzyme Database: 
CAS: 
119699-80-8

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