KEGG   ENZYME: 6.3.2.32Help
Entry
EC 6.3.2.32                 Enzyme                                 

Name
coenzyme gamma-F420-2:alpha-L-glutamate ligase;
MJ1001;
CofF protein;
gamma-F420-2:alpha-L-glutamate ligase
Class
Ligases;
Forming carbon-nitrogen bonds;
Acid-D-amino-acid ligases (peptide synthases)
BRITE hierarchy
Sysname
L-glutamate:coenzyme gamma-F420-2 (ADP-forming)
Reaction(IUBMB)
ATP + coenzyme gamma-F420-2 + L-glutamate = ADP + phosphate + coenzyme alpha-F420-3 [RN:R09401]
Reaction(KEGG)
Substrate
ATP [CPD:C00002];
coenzyme gamma-F420-2;
L-glutamate [CPD:C00025]
Product
ADP [CPD:C00008];
phosphate [CPD:C00009];
coenzyme alpha-F420-3
Comment
The enzyme caps the gamma-glutamyl tail of the hydride carrier coenzyme F420 [1].
History
EC 6.3.2.32 created 2010
Pathway
ec00680  Methane metabolism
ec01120  Microbial metabolism in diverse environments
Orthology
K14940  gamma-F420-2:alpha-L-glutamate ligase
Genes
SON: SO_2200(rimK)
SAZ: Sama_1999
SBL: Sbal_1848
SBM: Shew185_1834
SBN: Sbal195_1882
SBP: Sbal223_2443
SBT: Sbal678_1921
SBS: Sbal117_1966
SBB: Sbal175_2505
SPC: Sputcn32_1744
PSEO: OM33_05960
PSPO: PSPO_a0609(cofF)
PTU: PTUN_a3869(cofF)
FBL: Fbal_3320
LHA: LHA_0303
LCD: clem_13645(rimK_3)
BMX: BMS_2472
SMAZ: LH19_12250
SPHM: G432_12675
MAI: MICA_511
MAN: A11S_494
BBEV: BBEV_0975(rimK-2)
VPN: A21D_03084(lysX)
PROC: Ptc2401_00937(lysX_1)
MJA: MJ_1001
MMP: MMP0170(cofF)
MMD: GYY_00870
MAE: Maeo_1379
MVO: Mvol_1455
MAC: MA_1361(rimK)
MMA: MM_2347
MMAC: MSMAC_2094
MHOR: MSHOH_2976
MMET: MCMEM_1893
MPY: Mpsy_2134(rimK)
 » show all
Taxonomy
Reference
1  [PMID:12909715]
  Authors
Li H, Xu H, Graham DE, White RH
  Title
Glutathione synthetase homologs encode alpha-L-glutamate ligases for methanogenic coenzyme F420 and tetrahydrosarcinapterin biosyntheses.
  Journal
Proc. Natl. Acad. Sci. U. S. A. 100 (2003) 9785-90.
  Sequence
[mja:MJ_1001]
Other DBs
ExplorEnz - The Enzyme Database: 6.3.2.32
IUBMB Enzyme Nomenclature: 6.3.2.32
ExPASy - ENZYME nomenclature database: 6.3.2.32
BRENDA, the Enzyme Database: 6.3.2.32

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