KEGG   ENZYME: 6.3.4.7Help
Entry
EC 6.3.4.7                  Enzyme                                 

Name
ribose-5-phosphate---ammonia ligase;
5-phosphoribosylamine synthetase;
ribose 5-phosphate aminotransferase;
ammonia-ribose 5-phosphate aminotransferase
Class
Ligases;
Forming carbon-nitrogen bonds;
Other carbon-nitrogen ligases
BRITE hierarchy
Sysname
ribose-5-phosphate:ammonia ligase (ADP-forming)
Reaction(IUBMB)
ATP + ribose 5-phosphate + NH3 = ADP + phosphate + 5-phosphoribosylamine [RN:R01053]
Reaction(KEGG)
Substrate
ATP [CPD:C00002];
ribose 5-phosphate [CPD:C00117];
NH3 [CPD:C00014]
Product
ADP [CPD:C00008];
phosphate [CPD:C00009];
5-phosphoribosylamine [CPD:C03090]
History
EC 6.3.4.7 created 1972
Pathway
Purine metabolism
Reference
1  [PMID:5699059]
  Authors
Reem GH.
  Title
Enzymatic synthesis of 5'-phosphoribosylamine from ribose 5-phosphate and ammonia, an alternate first step in purine biosynthesis.
  Journal
J. Biol. Chem. 243 (1968) 5695-701.
  Organism
duck, Gallus gallus, pigeon
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
9082-52-4

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