| Entry |
|
|---|
| Name |
RNA-3'-phosphate cyclase;
RNA cyclase
|
|---|
| Class |
Ligases;
Forming phosphoric-ester bonds;
Ligases that form phosphoric-ester bonds (only sub-subclass identified to date)
 |
|---|
| Sysname |
RNA-3'-phosphate:RNA ligase (cyclizing, AMP-forming)
|
|---|
| Reaction(IUBMB) |
ATP + RNA 3'-terminal-phosphate = AMP + diphosphate + RNA terminal-2',3'-cyclic-phosphate [RN: R04274]
|
|---|
| Reaction(KEGG) |
|
|---|
| Substrate |
|
|---|
| Product |
AMP [CPD: C00020];
diphosphate [CPD: C00013];
RNA terminal-2',3'-cyclic-phosphate [CPD: C04312]
|
|---|
| Comment |
Adenosine 5'-(gamma-thio)triphosphate can act instead of ATP.
|
|---|
| Orthology |
| RNA 3'-terminal phosphate cyclase |
|
|---|
| Genes |
HSA: | | PTR: | | PPS: | | GGO: | | PON: | | MCC: | | MMU: | | RNO: | | CFA: | | AML: | | FCA: | | BTA: | | SSC: | | ECB: | | MDO: | | SHR: | | OAA: | | GGA: | | MGP: | | TGU: | | ACS: | | XLA: | | XTR: | | DRE: | | TRU: | | OLA: | | BFO: | | CIN: | | SPU: | | DME: | | DPO: | | DAN: | | DER: | | DPE: | | DSE: | | DSI: | | DWI: | | DYA: | | DGR: | | DMO: | | DVI: | | AGA: | | AAG: | | CQU: | | AME: | | TCA: | | API: | | PHU: | | TSP: | | SMM: | | NVE: | | HMG: | | AQU: | | SMO: | | VCN: | | SMP: | | PAN: | | TTT: | | MTM: | | FGR: | | NHE: | | VAL: | | BFU: | | ANI: | | NFI: | | AFM: | | AFV: | | ACT: | | PCS: | | CPW: | | ABE: | | TVE: | | PNO: | | PTE: | | ZTR: | | PPL: | | LBC: | | MPR: | | CCI: | | SCM: | | UMA: | | NGR: | | DDI: | | DPP: | | EHI: | | EDI: | | TET: | | PTM: | | PTI: | | ECO: | | ECJ: | | ECD: | | EBW: | | ECOK: | | ECE: | | ECS: | | ECF: | | ETW: | | ELX: | | EOJ: | | EOI: | | EOH: | | ECG: | | EOK: | | ELR: | | ECC: | | ECP: | | ECI: | | ECV: | | ECX: | | ECW: | | ECM: | | ECY: | | ECR: | | ECQ: | | ECK: | | ECT: | | EOC: | | EUM: | | ECZ: | | ELO: | | ELN: | | ELH: | | ESE: | | ESO: | | ESM: | | ESL: | | ECL: | | EBR: | | EBD: | | EKO: | | EKF: | | EAB: | | EDH: | | EDJ: | | EIH: | | ENA: | | ELU: | | EUN: | | ELW: | | ELL: | | ELC: | | ELD: | | ELP: | | EBL: | | EBE: | | ELF: | | ECOA: | | EFE: | | STM: | | SEO: | | SEV: | | SEY: | | SEM: | | SEJ: | | SEB: | | SEF: | | SEI: | | SEC: | | SEH: | | SHB: | | SEA: | | SEG: | | SEL: | | SET: | | SFL: | | SFX: | | SFV: | | SFE: | | SSN: | | SSJ: | | SBO: | | SBC: | | SDY: | | PAE: | | PAU: | | PAG: | | PAF: | | PNC: | | PDK: | | PFL: | | PFO: | | PMY: | | PFV: | | ACD: | | ACB: | | ABAD: | | TTU: | | MCA: | | MMT: | | NHL: | | TGR: | | TNI: | | HCH: | | RSO: | | RSC: | | RSL: | | RSN: | | POL: | | PNA: | | AAA: | | ACK: | | DAC: | | DEL: | | VAP: | | VPE: | | NII: | | NMU: | | APP: | | GUR: | | GBM: | | GEO: | | GEM: | | GEB: | | PCA: | | ADE: | | ACP: | | AFW: | | ANK: | | MXA: | | MFU: | | MSD: | | CCX: | | SUR: | | SCL: | | HOH: | | SAT: | | DAO: | | DTI: | | SFU: | | DBR: | | SSY: | | AZL: | | DAU: | | ABA: | | RMR: | | RMG: | | RBA: | | PSL: | | IPA: | | SACI: | | CYC: | | CYJ: | | GLP: | | ANA: | | NPU: | | NOP: | | AVA: | | CSG: | | CALO: | | OAC: | | CEP: | | MIC: | | PLP: | | AAE: | | TID: | | TOP: | | MOX: | | MJA: | | MFE: | | MVU: | | MFS: | | MIF: | | MIG: | | MMP: | | MMQ: | | MMX: | | MMZ: | | MMD: | | MAE: | | MVN: | | MOK: | | MAC: | | MBA: | | MMA: | | MMAZ: | | MBU: | | MMH: | | MEV: | | MZH: | | MPY: | | MHZ: | | MTP: | | MCJ: | | MHI: | | MEM: | | MBG: | | MPL: | | MPD: | | MEZ: | | RCI: | | MTH: | | MMG: | | MEL: | | MEW: | | MFV: | | MKA: | | AFU: | | APO: | | AVE: | | FPL: | | HAL: | | HSL: | | NPH: | | HUT: | | HTU: | | NMG: | | HVO: | | HME: | | HBO: | | HXA: | | NAT: | | NPE: | | NGE: | | HRU: | | NOU: | | TAR: | | PHO: | | PAB: | | PFU: | | PFI: | | PYN: | | PYA: | | PYS: | | TKO: | | TON: | | TGA: | | TSI: | | TBA: | | THE: | | THA: | | THM: | | ABI: | | ACF: | | APE: | | SMR: | | SHC: | | IHO: | | DKA: | | DMU: | | DFD: | | TAG: | | IAG: | | THG: | | HBU: | | PFM: | | SSO: | | SOL: | | STO: | | SAI: | | SACN: | | SACR: | | SIS: | | SIA: | | SIM: | | SID: | | SIY: | | SIN: | | SII: | | SIH: | | SIR: | | SIC: | | MSE: | | MCN: | | AHO: | | PAI: | | PIS: | | PCL: | | PAS: | | PYR: | | POG: | | CMA: | | TNE: | | TUZ: | | TTN: | | VDI: | | VMO: | | TPE: | | ASC: | | FFO: | | NMR: | | NIR: | | NKR: | | CSY: | | NGA: | | KCR: | |
» show all
 |
|---|
| Reference |
|
|---|
| Authors |
Filipowicz W, Konarska M, Gross HJ, Shatkin AJ. |
|---|
| Title |
RNA 3'-terminal phosphate cyclase activity and RNA ligation in HeLa cell extract. |
|---|
| Journal |
Nucleic. Acids. Res. 11 (1983) 1405-18. |
|---|
| Organism |
|
|---|
| Reference |
|
|---|
| Authors |
Reinberg D, Arenas J, Hurwitz J. |
|---|
| Title |
The enzymatic conversion of 3'-phosphate terminated RNA chains to 2',3'-cyclic phosphate derivatives. |
|---|
| Journal |
J. Biol. Chem. 260 (1985) 6088-97. |
|---|
| Organism |
|
|---|
| Other DBs |
ExplorEnz - The Enzyme Database: IUBMB Enzyme Nomenclature: ExPASy - ENZYME nomenclature database: BRENDA, the Enzyme Database: CAS: 85638-41-1 |
|---|
