KEGG   Equus caballus (horse): 100034074
Entry
100034074         CDS       T01058                                 
Symbol
ABCB1
Name
(RefSeq) multidrug resistance protein 1
  KO
K05658  ATP-binding cassette, subfamily B (MDR/TAP), member 1 [EC:7.6.2.2]
Organism
ecb  Equus caballus (horse)
Pathway
ecb02010  ABC transporters
ecb04976  Bile secretion
ecb05206  MicroRNAs in cancer
ecb05226  Gastric cancer
Brite
KEGG Orthology (KO) [BR:ecb00001]
 09130 Environmental Information Processing
  09131 Membrane transport
   02010 ABC transporters
    100034074 (ABCB1)
 09150 Organismal Systems
  09154 Digestive system
   04976 Bile secretion
    100034074 (ABCB1)
 09160 Human Diseases
  09161 Cancer: overview
   05206 MicroRNAs in cancer
    100034074 (ABCB1)
  09162 Cancer: specific types
   05226 Gastric cancer
    100034074 (ABCB1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters [BR:ecb02000]
    100034074 (ABCB1)
   04147 Exosome [BR:ecb04147]
    100034074 (ABCB1)
   04090 CD molecules [BR:ecb04090]
    100034074 (ABCB1)
Enzymes [BR:ecb01000]
 7. Translocases
  7.6  Catalysing the translocation of other compounds
   7.6.2  Linked to the hydrolysis of a nucleoside triphosphate
    7.6.2.2  ABC-type xenobiotic transporter
     100034074 (ABCB1)
Transporters [BR:ecb02000]
 ABC transporters, eukaryotic type
  ABCB (MDR/TAP) subfamily
   ABCB1, 4, 5 subgroups
    100034074 (ABCB1)
Exosome [BR:ecb04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   100034074 (ABCB1)
CD molecules [BR:ecb04090]
 Proteins
  100034074 (ABCB1)
SSDB
Motif
Pfam: ABC_membrane ABC_tran SMC_N ABC_ATPase AAA_16 AAA_22 Zeta_toxin RsgA_GTPase AAA_5 Rad17 AAA AAA_29 AAA_14 G-alpha APS_kinase DUF87 SbcC_Walker_B AAA_28 AAA_7 DUF815 nSTAND1 AAA_15 DUF2207_C GxGYxYP_N_2nd NTPase_1
Other DBs
NCBI-GeneID: 100034074
NCBI-ProteinID: XP_014594657
Ensembl: ENSECAG00000017842
VGNC: 14907
UniProt: A0A3Q2KSZ8
Position
4:complement(31862516..32058379)
AA seq 1275 aa
MDLEGGRNRRRGKKNFLKINEESKKDEKKEKKPTVSIFAMFRYSNWLDKLYMLLGTTAAI
IHGAGLPLMMLVFGQMTDSFANVGNVGNESYPSNGSPTPFENLEEEMTKYAYYYSGIGAG
VLVAAYIQVSFWCLAAGRQIYKIRKQFFHAIMQQEIGWFDMHDVGELNTRLTDDVSKINE
GIGDKIGMFFQSMATFFTGFIVGFTRGWKLTLVILAISPVLGLSAGIWAKILSSFTDKEL
LAYAKAGAVAEEVLAAIRTVIAFGGQKKELERYNKNLEEAKRIGIKKAITANISMGAAFL
LIYASYALAFWYGTSLVLSGEYSIGQVLTVFFSVLIGAFSVGQASPSIEAFANARGAAYE
IFKIIDNKPSIDSYSKNGHKPDNIKGNLEFRNVHFSYPSRNEVKILKGLNLKVRSGQTVA
LVGNSGCGKSTTVQLMQRLYDPTEGVVSIDGQDIRTINVRYLREITGVVSQEPVLFATTI
AENIRYGRENVTMDEIVKAVKEANAYDFIMKLPNKFDTLVGERGAQLSGGQKQRIAIARA
LVRNPKILLLDEATSALDTESEAVVQVALDKARKGRTTIVIAHRLSTVRNADVIAGLDDG
VIVEEGNHDELMKEKGIYFKLVTMQTRGNEIELESAIGESQSEIDALEMSPKDSGSSLIR
RRSTRKSIREPQGQERKLSTKEALDENVPPVSFWRILKLNITEWPYFVVGIFCAIINGGL
QPAFSIIFSRIIGVFTRDEDPETKRQNSNMFSLLFLVLGIISFITFFLQGYTFGKAGEIL
TKRLRYLVFRSMLRQDVSWFDNPKNTTGALTTRLANDAGQVKGAIGSRLAVITQNIANLG
TGIIISFIYGWQLTLLLLAIVPIIAIAGVVEMKMLSGQALKDKKKLEGAGKVATEAIENF
RTVVSLTREQKFEDMYAEKLQVPYRNSLRKAHVFGITFSITQAMMYFSYAGCFRFGAFLV
ARQLMNFQDVLLVFSAIVFGAMAVGQVSSFAPDYAKAKVSAAHIIMIIEKTPLIDSYSTE
GLKPNTLEGNVIFNEVVFNYPTRPDIPVLQGLSVEVKKGQTLALVGSSGCGKSTLVQLLE
RFYDPMAGTVLLDGTEIKHLNVQWLRAHLGIVSQEPILFDCSIGENIAYGDNSRVVSQEE
IVQAAKEANIHPFIETLPDKYNTRVGDKGTQLSGGQKQRIAIARALVRQPQILLLDEATS
ALDTESEKVVQEALDKAREGRTCIVIAHRLSTIQNADLIVVFQNGKVKERGTHQQLLAQK
GIYFSMVSVQAGAKR
NT seq 3828 nt   +upstreamnt  +downstreamnt
atggatcttgaaggaggccgcaatagaagaagggggaagaagaacttcttgaaaattaac
gaagaaagtaaaaaagatgagaagaaagaaaagaaaccaactgttagtatatttgcaatg
tttcgctattcaaattggcttgataagttgtatatgttgctggggactacggctgccatc
atccatggagctggactccccctcatgatgctggtttttggacaaatgacggatagcttt
gcaaatgtaggaaatgtaggaaacgagtcttatccaagtaatggcagccctacacctttc
gagaacctggaggaggaaatgaccaagtatgcctattattacagtggaattggtgctggt
gtgcttgttgctgcttacattcaggtttcattctggtgcctggcagctggaagacaaata
tacaaaattagaaaacaattttttcatgctataatgcaacaggagataggctggtttgac
atgcatgatgttggggagcttaacacacggctcacagatgatgtctccaaaattaatgaa
ggaattggtgacaaaattggaatgttctttcagtcgatggcaacatttttcaccggtttt
atagtaggatttacccgtggttggaagctaacccttgtgattttggccatcagtcctgtt
cttggactgtcagctggcatctgggcaaagatactctcttcatttactgataaagaactc
ttggcatatgcaaaagctggagctgtagctgaagaggtcttagcagcaattagaaccgtg
attgcatttggaggacagaagaaagaactggaaaggtacaacaaaaatttagaagaagct
aaaagaattgggataaagaaagctattacagccaacatttctatgggtgctgctttcctg
ttgatctatgcctcatatgctctggcattctggtatgggacctccttggtcctctcagga
gaatattctattggacaagtactcactgtcttcttttctgtattaattggggcttttagt
gttggacaggcgtctccaagcattgaagcatttgcaaacgcaagaggagcagcttatgaa
atcttcaagataattgataacaagccaagcattgacagctattcgaagaatgggcacaaa
ccagataatataaaagggaatttggaattcagaaacgttcacttcagttatccatctcga
aatgaagtcaagatcttgaagggcctcaacctgaaggttcgaagtgggcagacagtggcc
ctcgttgggaacagcggctgtgggaaaagcacgacggtccagctgatgcagaggctctat
gaccccacggagggcgtggtcagtattgatggacaggacattaggaccataaacgtaagg
tatctgcgggaaattactggtgtggtgagtcaggaacctgtgttgtttgccaccacaata
gctgaaaacattcgctatggccgtgaaaatgtcaccatggatgagattgtgaaagccgtc
aaggaagctaacgcctatgactttatcatgaaactgcctaataaatttgacaccctggtt
ggagagagaggggcccagctgagtgggggacagaaacagagaattgccatcgcacgagcc
ctggttcgtaaccccaagatcctcctgctggacgaggccacgtcagccttggacactgaa
agtgaagcagtagttcaggtggccctggataaggccagaaaaggccggaccaccattgtg
atagctcatcgcttgtctacagttcgtaatgctgatgtcatcgctggtttggatgatgga
gtcattgtggaggaaggaaatcacgatgaactcatgaaagagaaaggcatttacttcaaa
ctcgtcacaatgcagacacgaggaaatgaaattgaattagaaagtgcaattggtgaatct
caaagtgaaattgatgccttggaaatgtctccaaaagattcaggatcaagtctaataaga
agaagatcaactcgcaagagtatccgtgaacctcaaggccaggagagaaagcttagtaca
aaagaggctctggatgaaaatgtacctccagtttccttttggaggattctgaagctgaat
ataaccgaatggccttattttgtagtgggcatattttgtgccatcataaatggaggcctg
caaccagcattttcaataatattttcaaggattataggggtttttaccagagatgaggat
cctgaaacaaaacgacagaatagtaacatgttttcactattgtttctagtccttggaatc
atttcttttattacatttttccttcagggctacacatttggcaaagctggagagatcctc
accaagcggctccgatacctggttttcagatccatgctgagacaggatgtgagctggttc
gacaatcctaaaaacaccactggagcattgactaccaggcttgccaacgatgctggtcaa
gttaaaggggctataggttccaggcttgctgtaattacccagaatatagcaaatcttggg
acaggcattataatatctttcatctatggctggcaattgacacttttactcttagctatt
gtacccatcattgcaatagcaggagttgttgaaatgaaaatgttgtctggacaagcactg
aaagataagaaaaaactagaaggtgctgggaaggttgctactgaagcaatagaaaacttc
cgaactgttgtttctttgactcgggagcagaagtttgaagatatgtatgcagagaaattg
caggtcccatatagaaactccctgaggaaagcacacgtctttggaatcacgttttccatc
acccaggcaatgatgtatttctcctatgctggctgtttccggtttggtgccttcttggtg
gcacggcagctcatgaactttcaggatgttctgttggtattctcagctatcgtctttgga
gccatggcagtggggcaggtcagttcatttgctcctgactatgccaaagccaaagtgtca
gcagcccacatcatcatgatcattgaaaaaacccctctgatcgacagctatagcacagaa
ggcctaaagccaaatacattggaaggaaatgtgatctttaatgaagttgtgttcaactat
cccactcgaccagacatcccagtgcttcaggggctgagcgttgaggtgaagaagggccag
acgctcgccctggtgggcagcagtggctgtgggaagagcacactggtccagctccttgag
cggttctatgaccccatggccggaacagtgctacttgacggcacagaaataaagcacctg
aatgtccagtggctccgagcacacctgggcattgtgtcccaggagcccatcctgtttgac
tgcagcattggtgagaacatcgcctatggagacaacagccgggtcgtgtcacaggaagag
attgtgcaggcagccaaggaggccaacatacaccccttcatcgagacactgcctgataaa
tataacaccagagtaggagacaaaggaactcagctctctggtggccagaaacagcgtatc
gcgatagctcgcgcccttgtgagacagcctcagattttgcttttggatgaagctacatca
gctctggatacagaaagtgaaaaggttgtccaagaagctctggacaaagccagagaaggc
cgcacctgcattgtgattgctcaccgtctgtccaccatccagaacgcagacttaatagtg
gtatttcagaatggcaaagtcaaggagcgtggcacacaccaacagttgctggcacagaaa
ggcatctatttttccatggtcagcgtccaggctggagcaaaacgctaa

  All links  
Ontology (5)   
   KEGG BRITE (5)   
Pathway (4)   
   KEGG PATHWAY (4)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (21)   
   KEGG ORTHOLOGY (1)   
   RefGene (15)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   VGNC (1)   
Protein sequence (2)   
   UniProt (1)   
   RefSeq(pep) (1)   
DNA sequence (3)   
   RefSeq(nuc) (1)   
   GenBank (1)   
   EMBL (1)   
Protein domain (25)   
   Pfam (25)   
All databases (62)   

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