KEGG   Equus caballus (horse): 100056103
Entry
100056103         CDS       T01058                                 
Symbol
AP2A1
Name
(RefSeq) AP-2 complex subunit alpha-1 isoform X1
  KO
K11824  AP-2 complex subunit alpha
Organism
ecb  Equus caballus (horse)
Pathway
ecb04144  Endocytosis
ecb04721  Synaptic vesicle cycle
ecb04961  Endocrine and other factor-regulated calcium reabsorption
ecb05016  Huntington disease
Brite
KEGG Orthology (KO) [BR:ecb00001]
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    100056103 (AP2A1)
 09150 Organismal Systems
  09155 Excretory system
   04961 Endocrine and other factor-regulated calcium reabsorption
    100056103 (AP2A1)
  09156 Nervous system
   04721 Synaptic vesicle cycle
    100056103 (AP2A1)
 09160 Human Diseases
  09164 Neurodegenerative disease
   05016 Huntington disease
    100056103 (AP2A1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:ecb04131]
    100056103 (AP2A1)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:ecb04147]
    100056103 (AP2A1)
Membrane trafficking [BR:ecb04131]
 Endocytosis
  Clathrin-mediated endocytosis
   AP-2 complex
    100056103 (AP2A1)
Exosome [BR:ecb04147]
 Exosomal proteins
  Exosomal proteins of colorectal cancer cells
   100056103 (AP2A1)
SSDB
Motif
Pfam: Adaptin_N Alpha_adaptin_C Alpha_adaptinC2 Cnd1 HEAT_2 RIX1 AcMNPV_Ac75 PDS5
Other DBs
NCBI-GeneID: 100056103
NCBI-ProteinID: XP_023505947
Ensembl: ENSECAG00000007134
VGNC: 15377
Position
10:19782673..19815526
AA seq 978 aa
MPAVSKGDGMRGLAVFISDIRNCKSKEAEIKRINKELANIRSKFKGDKALDGYSKKKYVC
KLLFIFLLGHDIDFGHMEAVNLLSSNKYTEKQIGYLFISVLVNSNSELIRLINNAIKNDL
ASRNPTFMCLALHCIANVGSREMGEAFAADIPRILVAGDSMDSVKQSAALCLLRLYKASP
DLVPMGEWTARVVHLLNDQHMGVVTAAVSLITCLCKKNPDDFKTCISLAVSRLSRIVSSA
STDLQDYTYYFVPAPWLSVKLLRLLQCYPPPEDAAVKGRLVECLETVLNKAQEPPKSKKV
QHSNAKNAILFETISLIIHYDSEPNLLVRACNQLGQFLQHRETNLRYLALESMCTLASSE
FSHEAVKTHIDTVINALKTERDVSVRQRAADLLYAMCDRSNAKQIVSEMLRYLETADYAI
REEIVLKVAILAEKYAVDYSWYVDTILNLIRIAGDYVSEEVWYRVLQIVTNRDDVQGYAA
KTVFEALQAPACHENMVKVGGYILGEFGNLIAGDPRSSPPVQFSLLHSKFHLCSVATRAL
LLSTYIKFINLFPETKATIQGVLRAGSQLRNADVELQQRAVEYLTLSSVASTDVLATVLE
EMPPFPERESSILAKLKRKKGPGAGSALDDGRRDPSSNDINGGVEPTPSTVSTPSPSADL
LGLRAAPPPAAPPAPSGAGNLLVDVFSDGPAAQPGLGPSAEEAFLSELEPPAPESPMALL
ADPAPAADPGPEDIGPPIPEADELLNKFVCKNNGVLFENQLLQIGVKSEFRQNLGRMYLF
YGNKTSVQFQNFSPTVVHPGDLQTQLAVQTKRVAAQVDGGAQVQQVLNIECLRDFLTPPL
LSVRFRYGGAPQSLTLKLPVTINKFFQPTEMAAQDFFQRWKQLSLPQQEAQKIFKANHPM
DAEVTKAKLLGFGSALLDNVDPNPENFVGAGIIQTKALQVGCLLRLEPNAQAQMYRLTLR
TSKEPVSRHLCELLAQQF
NT seq 2937 nt   +upstreamnt  +downstreamnt
atgccggccgtgtccaagggcgatgggatgcgggggctcgcggtgttcatctccgacatc
cggaactgcaagagcaaggaggcagagattaagagaatcaataaggaattggccaacatc
cgctccaagttcaaaggggacaaagccttggatggctacagtaagaaaaaatacgtgtgt
aaactgctcttcatcttcctgcttggccatgacattgactttgggcacatggaggccgtg
aacctgctcagctccaacaagtacacggagaaacagataggctacctgttcatctcggtg
ctggtgaactcgaactcggagctgatccggctcatcaacaacgccatcaagaacgacctg
gccagccgcaaccccaccttcatgtgcctggccctgcactgcatcgccaatgtgggcagc
cgtgagatgggcgaggccttcgccgctgacatccctcgcattctggtggccggggacagc
atggacagcgtgaagcagagcgcggccctgtgcctgctgcggctctacaaggcctcgccc
gacctggtgcccatgggcgagtggacagcccgcgtggtgcatctgctcaacgaccagcac
atgggtgtggtcacggccgctgtcagcctcatcacctgtctctgcaagaagaaccccgac
gacttcaagacgtgcatctccctggctgtgtctcgcctgagccggatcgtctcctcggcc
tccaccgacctccaggactacacttactacttcgtgcccgcgccctggctctcggtgaag
ctgctccggctgctccagtgctaccccccgccagaggatgcggctgtgaaggggcggctg
gtggagtgtctggagacggtgctcaacaaggcccaggagccgcccaagtccaagaaggtc
cagcactccaatgccaagaacgccatcctcttcgagaccatcagcctcatcatccactac
gacagtgagcccaacctcctggtgcgggcctgtaaccagctgggccagttcctgcagcac
cgggagaccaacctgcgctacctggcgctggagagcatgtgcacgctggccagctccgag
ttctcccacgaggcagtcaagacccacatcgacaccgtcatcaatgccctcaagacggag
cgggatgtcagcgttcggcaacgtgcagccgacctcctctatgccatgtgcgaccggagc
aatgccaagcagattgtgtcggagatgctgcggtacctggagacagctgactacgccatc
cgagaggagatcgtcctcaaggtggccatcctggccgagaagtacgcagtcgactacagc
tggtacgtggacaccatcctcaacctcatccgcatcgcaggcgactacgtgagcgaggag
gtctggtaccgtgtgctgcagatagtcaccaaccgcgatgacgttcagggctatgccgcc
aagaccgtctttgaggcgctccaggcccccgcctgtcatgagaacatggtgaaggttggc
ggctatatccttggggagtttgggaacctgattgctggggacccccgctccagccccccg
gtgcagttctcgctgctgcactccaagttccacctgtgcagcgtggccacgcgggccctg
ctgctgtccacctacatcaagttcatcaacctcttccccgagaccaaggccaccatccag
ggcgtgctgcgggccggctcccagctgcgcaacgccgacgtggagctgcagcagcgcgcc
gtcgagtacctcaccctcagctccgtggccagcacggacgtcctggccacggtgctggag
gagatgccgcccttccccgagcgcgagtcgtccatcctggccaagctgaaacgcaagaag
gggccgggggccggcagcgccctggatgacggccggagggaccccagcagcaacgacatc
aacgggggtgtggagcccacccccagcaccgtgtcgacaccctccccatccgccgacctc
ctggggctgcgggcagctcctccccctgcggccccgccggccccctcgggcgcaggcaac
ctcctggtggatgtgttctccgacggccccgccgcgcagcccggcctggggcccagcgcc
gaggaggccttcctcagcgagctggagccgcctgcccctgagagccccatggctttgctg
gctgacccagctccagctgctgacccaggtcctgaggacatcggcccacccatcccggaa
gccgatgaactgctgaataagttcgtgtgcaagaacaacggggtcctgtttgagaaccag
ctgctgcagataggagtcaagtcggagttccggcagaacctgggccgcatgtatctcttc
tatggcaacaagacttccgtacagttccagaacttctcgcccaccgtcgtccaccccgga
gacctccagactcagctggccgtgcagaccaagcgcgtggccgcgcaggtggacggcggc
gcacaggtgcagcaggtgctcaacatcgagtgtctgcgggacttcttgacgcccccgctc
ctgtccgtgcgcttccggtacgggggcgccccgcagtccctcaccctgaagctgccggtg
accatcaacaagttcttccagcccacagagatggcggcgcaggacttcttccagcgctgg
aagcagctgagcctcccccaacaggaggcgcagaaaatcttcaaggccaaccaccccatg
gacgcggaagttaccaaggccaagctcctggggttcggctctgctctcctcgacaacgtg
gaccccaatcctgagaacttcgtgggggctggaattatccagactaaagccctgcaggtg
ggctgcctgctccggctggagcccaacgcccaggctcagatgtaccggctgaccctgcgc
accagcaaggagcccgtctcccgtcatctgtgtgagctgctggcccagcagttctga

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (4)   
   KEGG PATHWAY (4)   
Genome (1)   
   KEGG GENOME (1)   
Gene (12)   
   KEGG ORTHOLOGY (1)   
   RefGene (6)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   VGNC (1)   
Protein sequence (2)   
   RefSeq(pep) (2)   
DNA sequence (2)   
   RefSeq(nuc) (2)   
Protein domain (8)   
   Pfam (8)   
All databases (32)   

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