KEGG   Equus caballus (horse): 100057961Help
Entry
100057961         CDS       T01058                                 

Gene name
MAPK9
Definition
(RefSeq) mitogen-activated protein kinase 9 isoform X1
  KO
K04440  mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
Organism
ecb  Equus caballus (horse)
Pathway
ecb01522  Endocrine resistance
ecb04010  MAPK signaling pathway
ecb04012  ErbB signaling pathway
ecb04014  Ras signaling pathway
ecb04024  cAMP signaling pathway
ecb04068  FoxO signaling pathway
ecb04071  Sphingolipid signaling pathway
ecb04137  Mitophagy - animal
ecb04140  Autophagy - animal
ecb04141  Protein processing in endoplasmic reticulum
ecb04210  Apoptosis
ecb04215  Apoptosis - multiple species
ecb04217  Necroptosis
ecb04310  Wnt signaling pathway
ecb04380  Osteoclast differentiation
ecb04510  Focal adhesion
ecb04530  Tight junction
ecb04620  Toll-like receptor signaling pathway
ecb04621  NOD-like receptor signaling pathway
ecb04622  RIG-I-like receptor signaling pathway
ecb04625  C-type lectin receptor signaling pathway
ecb04657  IL-17 signaling pathway
ecb04658  Th1 and Th2 cell differentiation
ecb04659  Th17 cell differentiation
ecb04664  Fc epsilon RI signaling pathway
ecb04668  TNF signaling pathway
ecb04722  Neurotrophin signaling pathway
ecb04723  Retrograde endocannabinoid signaling
ecb04728  Dopaminergic synapse
ecb04750  Inflammatory mediator regulation of TRP channels
ecb04910  Insulin signaling pathway
ecb04912  GnRH signaling pathway
ecb04914  Progesterone-mediated oocyte maturation
ecb04917  Prolactin signaling pathway
ecb04920  Adipocytokine signaling pathway
ecb04926  Relaxin signaling pathway
ecb04930  Type II diabetes mellitus
ecb04931  Insulin resistance
ecb04932  Non-alcoholic fatty liver disease (NAFLD)
ecb04933  AGE-RAGE signaling pathway in diabetic complications
ecb05132  Salmonella infection
ecb05133  Pertussis
ecb05142  Chagas disease (American trypanosomiasis)
ecb05145  Toxoplasmosis
ecb05152  Tuberculosis
ecb05160  Hepatitis C
ecb05161  Hepatitis B
ecb05164  Influenza A
ecb05167  Kaposi's sarcoma-associated herpesvirus infection
ecb05168  Herpes simplex infection
ecb05169  Epstein-Barr virus infection
ecb05200  Pathways in cancer
ecb05210  Colorectal cancer
ecb05212  Pancreatic cancer
ecb05231  Choline metabolism in cancer
ecb05418  Fluid shear stress and atherosclerosis
Module
ecb_M00688  MAPK (JNK) signaling
Brite
KEGG Orthology (KO) [BR:ecb00001]
 Genetic Information Processing
  Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    100057961 (MAPK9)
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    100057961 (MAPK9)
   04010 MAPK signaling pathway
    100057961 (MAPK9)
   04012 ErbB signaling pathway
    100057961 (MAPK9)
   04310 Wnt signaling pathway
    100057961 (MAPK9)
   04668 TNF signaling pathway
    100057961 (MAPK9)
   04068 FoxO signaling pathway
    100057961 (MAPK9)
   04071 Sphingolipid signaling pathway
    100057961 (MAPK9)
   04024 cAMP signaling pathway
    100057961 (MAPK9)
 Cellular Processes
  Transport and catabolism
   04140 Autophagy - animal
    100057961 (MAPK9)
   04137 Mitophagy - animal
    100057961 (MAPK9)
  Cell growth and death
   04210 Apoptosis
    100057961 (MAPK9)
   04215 Apoptosis - multiple species
    100057961 (MAPK9)
   04217 Necroptosis
    100057961 (MAPK9)
  Cellular community - eukaryotes
   04510 Focal adhesion
    100057961 (MAPK9)
   04530 Tight junction
    100057961 (MAPK9)
 Organismal Systems
  Immune system
   04620 Toll-like receptor signaling pathway
    100057961 (MAPK9)
   04621 NOD-like receptor signaling pathway
    100057961 (MAPK9)
   04622 RIG-I-like receptor signaling pathway
    100057961 (MAPK9)
   04625 C-type lectin receptor signaling pathway
    100057961 (MAPK9)
   04658 Th1 and Th2 cell differentiation
    100057961 (MAPK9)
   04659 Th17 cell differentiation
    100057961 (MAPK9)
   04657 IL-17 signaling pathway
    100057961 (MAPK9)
   04664 Fc epsilon RI signaling pathway
    100057961 (MAPK9)
  Endocrine system
   04910 Insulin signaling pathway
    100057961 (MAPK9)
   04920 Adipocytokine signaling pathway
    100057961 (MAPK9)
   04912 GnRH signaling pathway
    100057961 (MAPK9)
   04914 Progesterone-mediated oocyte maturation
    100057961 (MAPK9)
   04917 Prolactin signaling pathway
    100057961 (MAPK9)
   04926 Relaxin signaling pathway
    100057961 (MAPK9)
  Nervous system
   04728 Dopaminergic synapse
    100057961 (MAPK9)
   04723 Retrograde endocannabinoid signaling
    100057961 (MAPK9)
   04722 Neurotrophin signaling pathway
    100057961 (MAPK9)
  Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    100057961 (MAPK9)
  Development
   04380 Osteoclast differentiation
    100057961 (MAPK9)
 Human Diseases
  Cancers
   05200 Pathways in cancer
    100057961 (MAPK9)
   05231 Choline metabolism in cancer
    100057961 (MAPK9)
   05210 Colorectal cancer
    100057961 (MAPK9)
   05212 Pancreatic cancer
    100057961 (MAPK9)
  Cardiovascular diseases
   05418 Fluid shear stress and atherosclerosis
    100057961 (MAPK9)
  Endocrine and metabolic diseases
   04930 Type II diabetes mellitus
    100057961 (MAPK9)
   04932 Non-alcoholic fatty liver disease (NAFLD)
    100057961 (MAPK9)
   04931 Insulin resistance
    100057961 (MAPK9)
   04933 AGE-RAGE signaling pathway in diabetic complications
    100057961 (MAPK9)
  Infectious diseases
   05132 Salmonella infection
    100057961 (MAPK9)
   05133 Pertussis
    100057961 (MAPK9)
   05152 Tuberculosis
    100057961 (MAPK9)
   05164 Influenza A
    100057961 (MAPK9)
   05161 Hepatitis B
    100057961 (MAPK9)
   05160 Hepatitis C
    100057961 (MAPK9)
   05168 Herpes simplex infection
    100057961 (MAPK9)
   05167 Kaposi's sarcoma-associated herpesvirus infection
    100057961 (MAPK9)
   05169 Epstein-Barr virus infection
    100057961 (MAPK9)
   05145 Toxoplasmosis
    100057961 (MAPK9)
   05142 Chagas disease (American trypanosomiasis)
    100057961 (MAPK9)
  Drug resistance
   01522 Endocrine resistance
    100057961 (MAPK9)
Enzymes [BR:ecb01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     100057961 (MAPK9)
Protein kinases [BR:ecb01001]
 Serine/threonine kinases: CMGC group
  MAPK family [OT]
   100057961 (MAPK9)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: Pkinase Pkinase_Tyr Kdo Kinase-like RIO1 APH FTA2 Haspin_kinase
Motif
Other DBs
NCBI-GeneID: 100057961
NCBI-ProteinID: XP_023472773
Ensembl: ENSECAG00000021489
Position
14
AA seq 424 aa AA seqDB search
MSDSKCDSQFYSVQVADSTFTVLKRYQQLKPIGSGAQGIVCAAFDTVLGVNVAVKKLSRP
FQNQTHAKRAYRELVLLKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIH
MELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTACTNF
MMTPYVVTRYYRAPEVILGMGYKENVDIWSVGCIMGELVKGCVLFQGTDHIDQWNKVIEQ
LGTPSADFMKKLQPTVRNYVENRPKYPGIKFEELFPDWIFPSESERDKIKTSQARDLLSK
MLVIDPDRRISVDEALRHPYITVWYDPAEAEAPPPQIYDAQLEEREHAIEEWKELIYKEV
MDWEERSKNGVVKDQPSDAAVSSNATPSRSSSINDISSMSTEQTLASDTDSSLDASTGPL
EGCR
NT seq 1275 nt NT seq  +upstreamnt  +downstreamnt
atgagtgacagtaaatgtgatagtcagttttacagtgtgcaagtggcagactcaactttc
actgtcctgaaacgttaccaacagttgaaacctattggctctggagcccaaggaattgtg
tgtgctgcttttgatacagttcttggggtaaatgttgcagtcaagaaactaagccgtcct
tttcagaatcaaactcatgcaaagagagcttatcgtgaactcgtcctcttaaaatgtgtc
aatcataaaaatataattagtttgttaaatgtgtttacaccacaaaaaactcttgaagaa
tttcaagatgtgtatttggtgatggaattaatggatgctaacttatgtcaggttattcat
atggagttggaccatgaaagaatgtcctaccttctttaccagatgctctgtggtattaaa
catctgcattcagctggtataattcatagagatttgaaacctagcaacatcgtagtgaaa
tcagactgcacccttaagatccttgacttcggcctggcccggacagcatgcaccaacttt
atgatgaccccctatgtggtaacgcggtattatcgggcaccagaagtcatcctgggcatg
ggctacaaggagaacgttgatatctggtcagtgggttgcatcatgggagagctggtgaaa
ggttgtgtgctattccaaggcacggaccatattgatcagtggaataaagttattgagcag
ctgggaacaccgtccgcagatttcatgaagaaacttcagccaactgtgaggaattacgta
gaaaacagacccaagtatcctggaatcaaatttgaagaactctttccagattggatattc
ccatcagaatcggaacgagacaaaataaaaacaagtcaagccagagacttgttatcaaag
atgttagtgatcgaccccgacaggcggatctctgtggacgaggccctgcgtcacccctac
atcacggtttggtatgaccctgcagaggcagaggcgccaccacctcaaatttatgatgcc
cagttggaagaaagagaacatgcaattgaagaatggaaagagctaatttacaaagaagta
atggattgggaagaaaggagcaagaatggtgttgtgaaagatcagccttcagatgcagca
gtaagcagcaacgccactccttctcggtcatcatctatcaatgacatttcatccatgtct
actgagcagaccctggcctcagacacagacagcagtctcgacgcctcaaccgggcccctt
gaaggttgtcgatga

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