KEGG   Equus caballus (horse): 100066282Help
Entry
100066282         CDS       T01058                                 

Gene name
SOS2
Definition
son of sevenless homolog 2 (Drosophila)
Orthology
K03099  
son of sevenless
Organism
ecb  Equus caballus (horse)
Pathway
MAPK signaling pathway
ErbB signaling pathway
Ras signaling pathway
Chemokine signaling pathway
FoxO signaling pathway
PI3K-Akt signaling pathway
Dorso-ventral axis formation
Focal adhesion
Gap junction
Jak-STAT signaling pathway
Natural killer cell mediated cytotoxicity
T cell receptor signaling pathway
B cell receptor signaling pathway
Fc epsilon RI signaling pathway
Neurotrophin signaling pathway
Regulation of actin cytoskeleton
Insulin signaling pathway
GnRH signaling pathway
Estrogen signaling pathway
Prolactin signaling pathway
Alcoholism
Hepatitis C
Pathways in cancer
Proteoglycans in cancer
MicroRNAs in cancer
Renal cell carcinoma
Endometrial cancer
Glioma
Prostate cancer
Chronic myeloid leukemia
Acute myeloid leukemia
Non-small cell lung cancer
Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:ecb00001]
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    100066282 (SOS2)
   04010 MAPK signaling pathway
    100066282 (SOS2)
   04012 ErbB signaling pathway
    100066282 (SOS2)
   04630 Jak-STAT signaling pathway
    100066282 (SOS2)
   04068 FoxO signaling pathway
    100066282 (SOS2)
   04151 PI3K-Akt signaling pathway
    100066282 (SOS2)
 Cellular Processes
  Cell motility
   04810 Regulation of actin cytoskeleton
    100066282 (SOS2)
  Cellular commiunity
   04510 Focal adhesion
    100066282 (SOS2)
   04540 Gap junction
    100066282 (SOS2)
 Organismal Systems
  Immune system
   04650 Natural killer cell mediated cytotoxicity
    100066282 (SOS2)
   04660 T cell receptor signaling pathway
    100066282 (SOS2)
   04662 B cell receptor signaling pathway
    100066282 (SOS2)
   04664 Fc epsilon RI signaling pathway
    100066282 (SOS2)
   04062 Chemokine signaling pathway
    100066282 (SOS2)
  Endocrine system
   04910 Insulin signaling pathway
    100066282 (SOS2)
   04912 GnRH signaling pathway
    100066282 (SOS2)
   04915 Estrogen signaling pathway
    100066282 (SOS2)
   04917 Prolactin signaling pathway
    100066282 (SOS2)
  Nervous system
   04722 Neurotrophin signaling pathway
    100066282 (SOS2)
  Development
   04320 Dorso-ventral axis formation
    100066282 (SOS2)
 Human Diseases
  Cancers
   05200 Pathways in cancer
    100066282 (SOS2)
   05231 Choline metabolism in cancer
    100066282 (SOS2)
   05206 MicroRNAs in cancer
    100066282 (SOS2)
   05205 Proteoglycans in cancer
    100066282 (SOS2)
   05214 Glioma
    100066282 (SOS2)
   05221 Acute myeloid leukemia
    100066282 (SOS2)
   05220 Chronic myeloid leukemia
    100066282 (SOS2)
   05211 Renal cell carcinoma
    100066282 (SOS2)
   05215 Prostate cancer
    100066282 (SOS2)
   05213 Endometrial cancer
    100066282 (SOS2)
   05223 Non-small cell lung cancer
    100066282 (SOS2)
  Substance dependence
   05034 Alcoholism
    100066282 (SOS2)
  Infectious diseases
   05160 Hepatitis C
    100066282 (SOS2)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
Ensembl: 
Position
1
AA seq 1266 aa AA seqDB search
VQDVEERVQKTFPHPIDKWAIADAQSAIEKRKRRHPLLLPVDKIHPSLKEVLGYKVDYHV
SLYIVAVLEYISADILKLAGNYVFNIRHYEISQQDIKVSMCADKVLMDMFDQDDIGLVSL
CEDEPSSSGELNYYDLVRTEIAEERQYLRELNMIIKVFREAFLSDRKLFKPSDIEKIFSN
ILDIHELTVKLLGLIEDTVEMTDESSPHPLAGSCFEDLAEEQAFDPYETLSQDILSPKFN
EHFSKLMARPAVALHFQSIADGFREAVRYVLPRLMLVPVYHCWHYFELLKQLKACSEEQE
DRECLNQAITALMNLQGSMDRIYKQYSPRRRPGDPVCPFYNRQLRSKHLAIKKMNEIQKN
IDGWEGKDIGQCCNEFIMEGPLTKIGAKHERHIFLFDGLMISCKPNHSQSRLPGYSSAEY
RLKEKFVMRKIQICDKEDTCECRHAFELVSKDENSITFAAKSAEEKNNWMAALISLHYRS
TLDRMLDSVLLKEENEQPLRLPSPEMYRFVVKDSEENIVFEDSLQSRSGIPIIKGGTVVK
LIERLTYHMYADPNFVRTFLTTYRSFCKPQELLSLLIERFEIPEPEPTEADKLAVEKGEQ
PISADLKRFRKEYVQPVQLRILNVFRHWVEHHFYDFERDLELLERLESFISSVRGKAMKK
WVESIAKIIKRKKQTQANGISHNITFESPPPPIEWHISRPGQFETFDLMTLHPIEIARQL
TLLESDLYRKVQPSELVGSVWTKEDKEINSPNLLKMIRHTTNLTLWFEKCIVEAENFEER
VAVLSRVIEILQVFQDLNNFNGVLEIVSAVNSVSVYRLDHTFEALQERKRRILDEAVELS
QDHFKKYLVKLKSINPPCVPFFGIYLTNILKTEEGNNDFLKKKGKDLINFSKRRKVAEIT
GEIQQYQNQPYCLRIEPEMRRFFENLNPMGSSSEKEFTDYLFNKSLEIEPRNCKQPPRFP
RKSTFSLKSPGIRPNTGRHGSTSGTLRGHPTPLEREPCKISFSRIAEAELGSAVSAPTSP
NTPSTPPASAASDLSVFPDVDLSASCGSNSIFAPVLLPHSKSFFSSCGSLHKLSDEPLIP
PPLPPRKKFDHDASNPKGNMKSDDDPPAIPPRQPPPPKVKPRVPAPSGAFEGSLHSPPPP
PPREPLPDTPPPVPLRPPEHFINCPFNLQPPPLGHLHRDPDWFRDVSTRPDSPNTPPSTP
SPRVPRRCCVLSSSHSNLTYPQAPPVPPRQNSSPHLPKLPPKTYKRELSHPPMYRLSLLE
NAETPQ
NT seq 3801 nt NT seq  +upstreamnt  +downstreamnt
gttcaagatgtggaggaacgagttcaaaagacctttccgcatccaattgataaatgggct
attgctgatgcacaatccgccatagagaaacgaaaacgaagacaccctctcttactgcct
gtggacaaaatccatccttcattgaaggaggttttagggtacaaagtggactaccatgtg
tccctgtatattgtggctgtactggagtatatctcagctgatattttaaaattggctggt
aattatgtttttaatattcgacattatgaaatatctcagcaggacattaaagtgtcaatg
tgtgcagataaggttttgatggacatgtttgatcaggatgacataggtttggtttctctc
tgtgaagatgagccgagttcttcaggtgaattgaattactatgaccttgtcagaactgaa
attgcagaagaaagacagtatctccgggaactaaatatgatcataaaagtatttcgagaa
gcctttctttctgacagaaagctgtttaaaccttctgatattgagaagattttcagtaac
attttagatatacatgaattgactgtgaaacttctaggtttgattgaggacacagttgag
atgactgatgaaagcagtcctcatcccttagctggcagctgtttcgaagatttggcagaa
gagcaggcttttgatccttatgaaacattatcacaggacatcctttcaccaaaattcaat
gaacatttcagtaagttgatggccagacctgcagtggctctacactttcagtccattgct
gatgggttcagagaggcggttcgttatgtccttccacgcctgatgcttgtgccagtgtat
cattgttggcactacttcgaattattaaagcaattgaaagcatgtagtgaagaacaagaa
gacagagaatgtttgaaccaagctattactgctctcatgaatctccagggtagtatggac
cgaatttataagcagtattcgcctagacgtcgacctggggatcctgtttgccctttttat
aatcgtcaattaagaagcaagcacctggctattaaaaaaatgaatgaaattcagaaaaac
atagatggatgggaaggcaaagacatcggacagtgttgtaatgaattcattatggaaggt
cctttgacaaaaattggtgctaaacatgaacggcatatttttctctttgatggcttaatg
attagctgcaaacccaatcatagccagtcgcggcttccagggtacagtagtgcagaatac
agactgaaagagaagtttgtcatgaggaaaatacaaatatgtgataaagaagacacttgc
gagtgcagacatgcttttgaattagtctccaaagatgaaaacagcatcacatttgctgcc
aagtctgccgaagagaagaataactggatggcagcactcatttctcttcattaccgtagc
acactggaccgaatgctggactcagtgttactgaaggaagaaaatgagcagccactgagg
ttaccaagtcctgagatgtatcgtttcgtggtgaaagactctgaggaaaacatagttttt
gaagacagcttgcaaagtagaagtggaatccccattattaaaggaggaactgtggtgaaa
ttaattgaaaggttgacatatcatatgtatgcagatcccaattttgttcgtacttttctt
actacatatcgttcattttgtaaaccacaggaattgctaagcttactaattgaacgattt
gaaattccagagccagaacctactgaagcagataaattggcagtagagaaaggcgagcag
cccatcagtgcagaccttaaaaggtttcgcaaggaatacgtccaaccagtacaacttagg
atcttaaatgtgtttcggcactgggttgaacaccatttttatgattttgaaagagatttg
gagttgcttgaacggctagaatccttcatttcaagtgtaagagggaaagctatgaagaaa
tgggtagagtcaattgctaagatcatcaagaggaagaaacagactcaggcaaacggaata
agccataatatcacctttgaaagcccaccccccccgattgaatggcacatcagcagaccc
gggcagttcgagacctttgatctcatgacacttcatccaatagaaattgcacgccagctg
acgcttttggaatctgatctctataggaaagtccagccttctgaacttgtagggagtgtg
tggaccaaagaagataaagaaataaattctccaaatttattaaaaatgattcgccacacc
acaaatctcaccctctggtttgaaaagtgcattgtggaagcagaaaactttgaggaacga
gtggcagtactaagtagagttatagaaattctgcaagtttttcaagatttgaataatttc
aatggcgtactggagatagtcagtgcagtgaattcagtgtcagtgtacagactagaccat
accttcgaggcattgcaggaaagaaaaaggagaattttggatgaagctgtggaattaagt
caagatcactttaaaaaatacctagtaaaacttaagtcaatcaatccaccttgtgtgcct
ttttttggaatatatttaacaaatattctgaagactgaagaagggaataatgatttttta
aaaaagaaagggaaagatttaatcaatttcagtaagaggaggaaagtagctgaaattact
ggagaaattcagcagtatcagaatcaaccttactgtttacggatagaaccagagatgagg
cggttctttgaaaaccttaaccccatgggaagttcttctgaaaaagagtttacggattat
ttgttcaacaaatcactagaaattgaaccccgcaactgcaaacagccacctcgatttcct
aggaaatcaactttctctttaaaatctcctggaataaggcctaacacgggccgacatggc
tctacctcaggcactttacgaggtcatcccaccccgttagaaagagaaccgtgtaaaatc
agctttagtcggattgctgaggctgagctgggatcagcagtgtcggcaccaacctctccc
aacacgccgtccaccccgccggcgtctgctgcttcagacctcagtgtgttcccagacgtg
gacctcagcgcttcctgtggcagcaatagcatctttgctccagtcctcttgccacactca
aagtccttcttcagttcatgcggtagtttacataaactaagtgacgagcccctgattcct
cctccgcttcctcctcggaagaagtttgatcacgatgcttcgaatcccaagggaaatatg
aaatctgatgatgaccctcctgctattccaccaagacaacctcctcctccaaaggtgaaa
cccagagttcccgctccttctggtgcatttgaggggtctctgcacagcccacctccaccg
ccgcccagagagcctcttcctgacacgcctccaccggttccccttcggcctccagaacac
tttataaactgtccgtttaatcttcagccacctcccctgggacatcttcacagagatcca
gactggttcagagacgttagcacacgaccagattcgcccaacactcctcccagcacaccg
tctccacgggtgccacgtcgatgctgtgtgctcagttctagtcacagtaatctcacttat
cctcaagctccccctgttccaccaaggcagaattcaagccctcacctaccaaaactgcca
ccaaagacttacaaacgggagctttcgcaccccccaatgtacagactgtctttgctagaa
aacgcggaaactcctcaatga

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