KEGG   Equus caballus (horse): 100070655
Entry
100070655         CDS       T01058                                 
Symbol
SRD5A2
Name
(RefSeq) 3-oxo-5-alpha-steroid 4-dehydrogenase 2
  KO
K12344  3-oxo-5-alpha-steroid 4-dehydrogenase 2 [EC:1.3.1.22]
Organism
ecb  Equus caballus (horse)
Pathway
ecb00140  Steroid hormone biosynthesis
ecb01100  Metabolic pathways
ecb05215  Prostate cancer
Module
ecb_M00976  C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone
Brite
KEGG Orthology (KO) [BR:ecb00001]
 09100 Metabolism
  09103 Lipid metabolism
   00140 Steroid hormone biosynthesis
    100070655 (SRD5A2)
 09160 Human Diseases
  09162 Cancer: specific types
   05215 Prostate cancer
    100070655 (SRD5A2)
Enzymes [BR:ecb01000]
 1. Oxidoreductases
  1.3  Acting on the CH-CH group of donors
   1.3.1  With NAD+ or NADP+ as acceptor
    1.3.1.22  3-oxo-5alpha-steroid 4-dehydrogenase (NADP+)
     100070655 (SRD5A2)
SSDB
Motif
Pfam: Steroid_dh DUF1295
Other DBs
NCBI-GeneID: 100070655
NCBI-ProteinID: XP_001501572
Ensembl: ENSECAG00000024330
VGNC: 23574
UniProt: F6YAW2
Position
15:66000411..66047100
AA seq 254 aa
MPVHCQQSPVLAGSATLAALGALVLYLAKPSGYGKYSESVMPAAIRLPARAAWFLQELPS
FAVPAGILARQPRSIFGQPATVLLGLFCAHYFHRTFVYSFLTRGRPFPVAFLFRGFVFCV
GNGLLQGYYLVYCAEYPAEWYTDLRFSVGVFLFLLGMGINIHSDYILRQLRKPGEIIYKI
PQGGLFTYVSGANFLGEIIEWSGYALASWSLPALAFAFFSLCFLGLRAFHHHRFYIKMFE
DYPKSRKALIPFIF
NT seq 765 nt   +upstreamnt  +downstreamnt
atgcccgttcactgccagcagagcccggtgctggcaggcagcgccactttggccgccctg
ggggcgctggtcctgtacctcgcgaagccctccggctacgggaagtactcggagagcgtg
atgcccgcggctatccgcctgcccgcccgtgccgcctggttcctgcaggagctgccctcc
ttcgcggtgcccgcggggatcctcgcccggcagcctcgctctatcttcggccagcctgcg
actgtgcttctgggcctcttctgcgcacattactttcacaggacatttgtttactcattt
ctcactagagggaggccttttccagttgcattccttttcagaggctttgtcttctgcgtg
ggaaatggactcctccaaggctactacctggtttactgtgctgaatatcctgctgagtgg
tacacagacctacggtttagcgtgggtgtcttcttatttctcttgggaatgggaatcaac
attcatagtgactatatattgcggcagctcaggaagcctggagaaatcatctataaaatt
ccacaaggtggcttgttcacctatgtttcgggagccaatttccttggtgaaatcattgaa
tggagcggctatgcactggcctcttggtccctcccagcacttgcatttgcatttttctct
ctttgtttccttgggctgcgagcttttcaccaccataggttctacatcaagatgtttgag
gactaccccaaatctcggaaagccctcattccattcatcttttaa

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (4)   
   KEGG PATHWAY (3)   
   KEGG MODULE (1)   
Chemical substance (11)   
   KEGG COMPOUND (11)   
Chemical reaction (5)   
   KEGG ENZYME (1)   
   KEGG REACTION (4)   
Genome (1)   
   KEGG GENOME (1)   
Gene (9)   
   KEGG ORTHOLOGY (1)   
   RefGene (3)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   VGNC (1)   
Protein sequence (2)   
   UniProt (1)   
   RefSeq(pep) (1)   
DNA sequence (2)   
   RefSeq(nuc) (2)   
Protein domain (2)   
   Pfam (2)   
All databases (38)   

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