KEGG   Equus caballus (horse): 100147102
Entry
100147102         CDS       T01058                                 
Symbol
APC2
Name
(RefSeq) adenomatous polyposis coli protein 2 isoform X1
  KO
K02085  adenomatosis polyposis coli protein
Organism
ecb  Equus caballus (horse)
Pathway
ecb04310  Wnt signaling pathway
ecb04390  Hippo signaling pathway
ecb04550  Signaling pathways regulating pluripotency of stem cells
ecb04810  Regulation of actin cytoskeleton
ecb04934  Cushing syndrome
ecb05010  Alzheimer disease
ecb05022  Pathways of neurodegeneration - multiple diseases
ecb05165  Human papillomavirus infection
ecb05200  Pathways in cancer
ecb05206  MicroRNAs in cancer
ecb05210  Colorectal cancer
ecb05213  Endometrial cancer
ecb05217  Basal cell carcinoma
ecb05224  Breast cancer
ecb05225  Hepatocellular carcinoma
ecb05226  Gastric cancer
Brite
KEGG Orthology (KO) [BR:ecb00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04310 Wnt signaling pathway
    100147102 (APC2)
   04390 Hippo signaling pathway
    100147102 (APC2)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    100147102 (APC2)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    100147102 (APC2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100147102 (APC2)
   05206 MicroRNAs in cancer
    100147102 (APC2)
  09162 Cancer: specific types
   05210 Colorectal cancer
    100147102 (APC2)
   05225 Hepatocellular carcinoma
    100147102 (APC2)
   05226 Gastric cancer
    100147102 (APC2)
   05217 Basal cell carcinoma
    100147102 (APC2)
   05213 Endometrial cancer
    100147102 (APC2)
   05224 Breast cancer
    100147102 (APC2)
  09172 Infectious disease: viral
   05165 Human papillomavirus infection
    100147102 (APC2)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    100147102 (APC2)
   05022 Pathways of neurodegeneration - multiple diseases
    100147102 (APC2)
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    100147102 (APC2)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:ecb01009]
    100147102 (APC2)
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:ecb03036]
    100147102 (APC2)
  09183 Protein families: signaling and cellular processes
   04812 Cytoskeleton proteins [BR:ecb04812]
    100147102 (APC2)
Protein phosphatases and associated proteins [BR:ecb01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-1
    PP1-interacting proteins (PIPs)
     100147102 (APC2)
Chromosome and associated proteins [BR:ecb03036]
 Eukaryotic type
  Centrosome formation proteins
   Other centriole associated proteins
    100147102 (APC2)
Cytoskeleton proteins [BR:ecb04812]
 Eukaryotic cytoskeleton proteins
  Microtubules
   Tubulin-binding proteins
    EB / APC
     100147102 (APC2)
SSDB
Motif
Pfam: APC_basic APC_rep APC_N_CC Suppressor_APC Arm_APC_u3 Arm APC_r SAMP MPS2 Sec7-like_HUS bZIP_1 Wtap PDC10_C HALZ Herpes_BLRF2
Other DBs
NCBI-GeneID: 100147102
NCBI-ProteinID: XP_023502048
Position
7:812205..835978
AA seq 2302 aa
MGLLGLLSLLHSAFFGDQTLQELKMTSSVAPYEQLVRQVEALKAENSHLRQELRDNSSHL
SKLETETSGMKEVLKRLQGKLEQEARVLVSSGQTEVLEQLKALQMDITSLYNLKFQPPAL
GPEPAAQTPEGSPVHGSGPSKDSFGELSRATIRLLEELDRERCFLLNEIEKEEKEKLWYY
SQLQGLSKRLDELPHVETQFSMQMDLIRQQLEFEAQHIRSLMEERFGTSDEMVQRAQIRA
SRLEQIDKELLSAQDRVQQTEPQALLAVKSMPLDEDTETEVPTHPEDGAPQPGNSKVEVV
FWLLSMLATRDQEDTARTLLAMSSSPESCVAMRRSGCLPLLLQILHGTEAGPGGRNGNPG
APGAKDARMRANAALHNIVFSQPDQGLARKEMRVLHVLEQIRAYCETCWDWLQARDGGPE
GGGAGGAPVPIEPQICQATCAVMKLSFDEEYRRAMNELGGLQAVAELLQVDYEMHGMTRD
PLNLALRRYAGMTLTNLTFGDVANKAALCARRGCMEAIVAQLASESEELHQVVSSILRNL
SWRADINSKKVLREVGSMTALMQCVLRATKESTLKSVLSALWNLSAHSTENKAAICQVDG
ALGFLVSTLTYKCQSSSLAIMESGGGILRNVSSLIATREDYRQVLRDHHCLQTLLQHLTS
HSLTIVSNACGTLWNLSARSARDQELLWDLGAVGMLRNLVHSKHKMIAMGSAAALRNLLA
HRPAKYQAAAAAVSPGACAPSLYVRKQRALEAELDARHLAQALDRLEAQGPPEAEAAAKK
PLPPLRHLDGLARDYASDSGCFDDDDAPSLAAAAATAEPASPAVLSLFLGSPFLQGQALA
RAPPARRGAPEAEKEAGGEAAVAARAKAKLALAVARIDRLVEDISALHTSSDDSFSLSSG
DPGQEAPREGRAQSCSPCRGPDGGRREAGSRAHPLLRLKAAHASLSNDSLNSGSTGDGPG
PREHTRPCQLAALAEYREGPPCTQARPSRLDLDPPGAQPEPAAQDAAAADARVRTIKLSP
TYQHVPLLEGAGRAGSGPPGAGSRKQAWLPAEALSKVPEKLGAEAAALCLSRCSSLSSLS
SAGRPGPSEAGDLDDSDSSLEGLEEAGPSEAALDGAWRGPGAASLPMAIPAPRRGRGLGV
EDATPSSSSENCVQETPLVLSRCSSVSSLGSFESPSIASSIPSDPCSGLGSGTVSPSELP
DSPGQTMPPSRSKTPPPAPAPPGERESTQFSLQWESYVKRFLDIADCRERCRLPSELDAG
SVRFTVEKPDENFSCASSLSALALHEHYVQKDVELRLLPPACPERGGGGGGGPGLHFAGH
RRRDEAAGRLEGPTAAEQELELLRECLGAAVPARLRKVASALVPGRRALPVPVYMLVPAP
AREDDSCTDSAEGTQANFSSTASLSDETLQGPPRDAPGGRADRQKPAGRAVPARQVVGHR
HRAGGAGRSWEQARGASRSRTGLELPLRRPPSAHTDGDGSHAGRARGDGALQSLCLTTPT
EEAVYCFYGDDSDEEPSRAAATPRRPSAIPRAVKRERPAGRKEAQAVPKPVPKPAPPARA
QPSLIADETPPRCSLSSSASSLGEPEPPAPAASRPRAREVAVTKDPGPGGGLAGSPSPRA
QAELLRRGIGSALPRRRPQAPAPRRRKPQAAQPDERPADGAQERGEEAAGSDHASDLDSV
EWRAIQEGANSIVTWLHQAAAAAATSEASSESDSILSFMSGLSVGSTLQPSPHRKGPRPR
AEGQAGSGVRPEKRDAALAQRGSGPRSSCGPEKPRGAQKTVPGVPAVLRGRTVIYVPSPA
PRAPPKAAPSPRAAPRKMGPPSPAQPAAPTKAPGLGQPRSRSLHRPGKISELVALSPPQR
SATPPARLAKTPSSSSSQTSPASQPLPRRSPPATQATGPLPGPGSSALPKTPARALLAKQ
HKTQKSPVRIPFMQRPARRGPPPLARAALEPGPRGRAGAEGGPGARGGRLGLVRVASARS
SGSESSDRSGFRRQLTFIKESPGLPRRRRAEPATSASTSATIPASQGGSPRRGRPALPAV
FLCSSRCDELRAAPRQAPGPHRLPAARPGPGERPPRRTSSESPSRLPVRTPATRPETVKR
YASLPHISVARRPDGAAPAPTADATRRSSDGEARPLPRVAAPGTTWRRIRDEDVPHILRS
TLPATALPLRGASPEEGPGGPPQRKTSDAVVQTEDFVATKTNSSTSPSLESREPPQVPAS
GPISLLGSDVDGPTPAKAPAAATFVHEGLVVAAGGFPASRHGSPSRSARVPPFNYVPSPM
VVAPTDSAVEKAPAADPASLLE
NT seq 6909 nt   +upstreamnt  +downstreamnt
atggggctcctggggctgctgagcctgctgcactcggccttcttcggggaccagacgctg
caggagctgaagatgacgagctccgtggcgccctacgagcagctggtgcggcaggtggag
gccttgaaggccgagaacagtcacctgaggcaggagctgcgggacaactcgagccacctg
tccaagctggagacggagacgtctggcatgaaggaggtcctgaagcgtttgcagggcaag
ctggagcaggaggcccgagtgctggtgtcctcgggccagacagaggtgctggagcagctg
aaagccctgcagatggacatcactagcctgtacaacctcaagttccagcccccagccctg
ggccccgagcccgctgcccagacccccgagggaagcccagtacacggctccgggccctct
aaggacagctttggggagctgagccgggccaccatccggctgctggaggaactggaccga
gaacggtgcttcctgttgaatgagattgagaaggaggagaaggagaagctctggtattac
tcgcagctgcagggcctgtccaagcgcctggacgagctcccgcacgtggagacgcagttc
tcgatgcagatggacctgatccggcagcagctggagttcgaggcccagcacatccgctcg
ctgatggaggagcgcttcggcacctcggacgagatggtgcagcgggcgcagatccgtgct
tcgcgcctggagcagatcgacaaggaattgctgtctgcgcaggaccgggtgcagcagacg
gagccccaggccctgctggcggtgaagtcgatgccactggacgaggacacggagactgag
gtccccacgcaccctgaggatggtgcccctcagccgggcaacagcaaggtggaggtggtc
ttctggctgctatccatgctggcgacgcgcgaccaggaggacacggcacgcacgctgctc
gccatgtccagctctcccgagagctgtgtggccatgcgccgctcgggctgcctgccgctg
ctgctgcagatcctgcacggcaccgaggccgggcctgggggtcgtaacgggaaccccggg
gcaccgggagccaaggacgcgcgcatgcgcgccaacgcggcgctgcacaacatcgtcttc
tcgcagcctgaccagggcctggcgcgcaaggagatgcgcgtcctgcacgtgctggagcag
atccgcgcctactgcgagacctgctgggactggctgcaggcccgggacggcgggcccgag
gggggcggcgccggcggcgcccccgtccccatcgagccgcagatctgccaggccacgtgt
gccgtgatgaagctgtccttcgatgaggagtatcgccgggccatgaacgagctgggcggg
ctgcaggccgtggcggagttgctgcaggtcgactacgagatgcacgggatgacccgggac
ccactcaacctcgccctgcgccgatacgccggcatgaccctcaccaatctcacctttggg
gacgtcgccaacaaggccgcactgtgcgcgcgccggggctgcatggaggccatcgtggcc
cagctggcgtccgagagtgaggagctccaccaggtggtgtccagcatcctgcgcaacctc
tcctggcgggctgacatcaacagcaagaaggtgctgagggaggtcggcagcatgacggcc
ctgatgcagtgtgtcctgagagccaccaaggagtccaccctgaagagcgtgctcagcgcc
ctgtggaacctctcggcgcacagcacggagaacaaggcggccatctgccaggtggacggc
gccctgggcttcctggtgagcacgctgacctacaagtgccagagcagctcgctggccatc
atggagagcggcggcggcatcctgcgcaacgtgtccagcctcatcgccacccgcgaggac
tacaggcaggtgctgcgggaccaccactgcctgcagacgctgctgcagcacctcacgtcg
cacagcctgaccatcgtgagcaacgcgtgcggcacgctctggaacctgtcggcccgcagc
gcgcgcgaccaggagctgctgtgggacctgggcgcggtgggcatgctgcgcaacctggtg
cactccaagcacaagatgatcgccatgggcagcgccgcggccctgcgcaacctgctggcc
caccggcccgccaagtaccaggcggccgccgccgccgtgtccccgggcgcctgcgcgccc
agcctgtacgtgcgcaagcagcgcgcgctcgaggccgagctggacgcgcgccacctggcc
caggcgctcgaccgcctggaggcgcagggcccgccagaggccgaggccgccgccaagaag
ccgctgccgccgctgcgccacctggacgggctggcccgcgactacgcctcggactccggc
tgcttcgacgacgacgacgcgccctccctggccgccgcggccgccaccgccgagccggcc
agccccgccgtgctgtccctcttcctgggcagccccttcctgcagggccaggcgctggcc
cgcgccccgcccgcccgccgcggcgccccggaggccgagaaggaggccggcggtgaggcg
gccgtggcggccagggccaaggccaagctggcgctggcggtggcgcggatcgaccggctg
gtggaggacatctcggccctgcacacctcatccgacgacagcttcagcctcagctccggg
gaccctgggcaggaggcgcctcgggagggccgcgcccagtcctgctcgccctgccggggg
cccgacggcgggcggcgggaggcgggcagccgggctcacccgctgctgcggctcaaggcg
gcccacgccagcctctccaacgacagcctcaacagcggcagcaccggcgacgggccgggt
ccccgtgagcacacgcggccctgtcagctggccgcgctggccgagtaccgcgaggggccc
ccgtgcactcaggcgcggcccagccgccttgaccttgacccgccgggggcccagcccgag
ccggcagcccaggacgccgcggccgccgacgcccgcgtgcgcaccatcaagctgtcgccc
acctaccagcacgtgccgctgctcgagggcgcgggcagggcgggctccgggccgccaggt
gcagggtcccggaagcaggcctggctgcccgcagaggccctgagcaaggtgccggagaag
ctgggggcggaggcggctgcgctctgcctgtcccgctgcagctccctgtcctcgctgtcc
tcggccggccgcccggggcccagcgaggccggggacctggacgacagtgactcgtccctg
gaggggctggaggaggcgggccccagcgaggcggcgctggacggggcctggcgggggccg
ggggccgcctccctgcccatggccatcccggcgccgcggcggggccggggcctgggggtg
gaggacgccacgccgtccagctcctcggagaactgcgtgcaggagacgccgctggtgctg
agccgctgcagctcggtgagctcgctgggcagcttcgagagcccgtccattgccagctcc
atccccagcgacccgtgcagcgggctgggcagcggcacggtcagccccagcgagctgccc
gacagccccgggcagaccatgccgccgagccgcagcaagacgccgccgccggcgcccgcg
cccccgggcgagcgcgagagcacgcagttcagcctgcagtgggagagctacgtgaagcgg
ttcctggacatcgccgactgccgcgagcgctgccgcctgccctccgagctggacgcgggc
agcgtgcgcttcaccgtggagaagccggacgagaacttctcgtgcgcctccagcctcagc
gcgctcgccctgcacgagcactacgtgcagaaggacgtggagctgcggctgctgccgccg
gcctgccccgagcggggcggcgggggtggcggaggccccggcctgcacttcgccgggcac
cgtcggcgggacgaggccgctggccgcctcgaggggccgacggccgctgagcaggagctg
gagctgctgcgagagtgcctgggcgcggccgtgcccgcccggctccgcaaggtggcctcg
gcgctggtgcccggccgccgcgcgctgccggtgcccgtctacatgctggtgcccgccccg
gcccgcgaggacgactcgtgcactgactcggccgagggcacgcaggccaacttctccagc
accgcctcgctcagcgacgagacgctgcaggggccccccagggacgcgcccggcgggcgt
gcggacaggcagaagcccgcgggccgtgcggtccctgccaggcaggtggtcgggcaccgg
cacagggcggggggcgcaggccggagctgggagcaggcccggggcgcgagcaggagccgg
actgggctggagctgcccctccgccggcccccgagcgcccacacagacggggatggctcc
cacgcgggccgggcgcgtggggacggcgccctgcagtcgctgtgtctcacgacgcccacc
gaggaggccgtctactgcttctacggcgacgactcggacgaggagccgtccagggcggcg
gccaccccgcggcggccgtccgccatcccccgggcggtgaagagggagcgtccagcgggc
aggaaggaggcgcaggccgtgcccaagcctgtgcccaagcctgcgccgcccgcccgggcc
cagcccagcctcatcgccgacgagacgccgccgcgctgctccctgagttcgtccgcgagc
tccctgggcgagcccgagcccccagcgccagcagcgagccggccccgagcccgcgaggtg
gccgtcaccaaggaccccggcccgggcggcgggctcgccggctcccccagcccgagggcc
caggcggagctgctgcggcgcggcatcggctcagccctgcccaggcgccgaccccaggca
ccagccccgcggcgacgcaagccccaagccgcccagccggacgagcggccggcagacggg
gcccaggagcgcggcgaggaggcagcgggctcagatcacgcctcagacctggacagcgtc
gagtggcgcgccatccaggagggcgccaactccatcgtcacgtggctgcaccaggcggca
gcggcagcggccaccagcgaggcctcgtctgagtctgactccatcctgtccttcatgtcg
gggctctcagtgggctccaccctgcagccctccccgcacaggaaggggccccggccacgg
gcggaaggccaggccggcagtggggtgcggccagagaaacgggatgcggccctggcccag
cgcggcagcgggccccgctcatcctgcggcccggagaagccacgaggcgctcagaagact
gtgcctggggtgccggctgtgctccggggccggacggtgatctacgtgcccagcccagcc
ccccgggcccccccaaaggccgcccccagcccccgtgctgcacccaggaagatgggaccc
cccagccccgcgcagccggcagcccccaccaaagcccccgggctggggcagccgcggtct
cggagcctgcaccggccgggcaagatctcggaattggtggcgctgagcccgccgcagagg
agcgccacaccacccgcacgcctcgccaagaccccctcgtccagctcctcccagacctcc
cctgcctcccagcccctgcccaggaggtcaccccccgccacccaggctacggggcccctg
cccggccccgggtcctcagcactgcccaagacgccggcgcgggccctgctggccaagcag
cacaagacgcagaagtcgcccgtgcgcatcccattcatgcagaggcccgcccggcggggg
ccgccgcccctggccagggcagcgctggagccgggccccaggggccgggcaggggccgaa
ggggggccgggcgcccgagggggccgcctgggcctggtgcgcgtggcctcggcccgctcc
agcggcagcgagtcctccgaccgctcgggcttccggcggcagctgacgttcatcaaggag
tcgccgggcctgccgcgccgccgccgcgcagaaccagccacctccgcctccacctccgcc
accatccccgcctcccagggcggctcgccccgccgcggccggcccgcgctgcccgccgtc
ttcctctgctcctcgcgctgcgacgagctgcgggcagccccgaggcaggccccgggcccc
catcggctccctgcagcccggcccggccccggagagcgaccgccgcggcgcaccagctcc
gagagcccgtcgcgcctgcccgtgcgcacgccggccacccggcccgagacagtcaagcgc
tacgcctcgctgccacacatcagcgtggcccgcaggcccgacggcgcggcccccgcaccc
acggccgacgccacccgccgcagcagcgacggcgaggcccggccactgcccagggtggcc
gcaccaggcaccacatggcgtcgcatccgggacgaggacgtcccgcacatcctgcggagc
acgctgcccgccactgccctgccgctgaggggcgcctcacccgaggagggtccgggcggc
cccccacagcgcaagaccagcgacgccgtggtccagacggaggacttcgtggccaccaag
accaactccagcacgtccccgagcctggagagcagggagcccccccaggttccggccagc
ggccccatctccctgctcggcagcgacgtggacgggcccacccctgccaaggcgcccgcc
gccgccaccttcgtccacgagggcctggtggtggccgcagggggcttccccgccagccgg
cacggctcccccagccgctcggcccgcgtgccgcccttcaactacgtgcccagccccatg
gtggtggcccccactgactcggccgtggagaaggcaccggccgccgaccccgccagcctc
ctggaatag

  All links  
Ontology (4)   
   KEGG BRITE (4)   
Pathway (16)   
   KEGG PATHWAY (16)   
Genome (1)   
   KEGG GENOME (1)   
Gene (137)   
   KEGG ORTHOLOGY (1)   
   RefGene (133)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (6)   
   RefSeq(pep) (6)   
DNA sequence (6)   
   RefSeq(nuc) (6)   
Protein domain (15)   
   Pfam (15)   
All databases (185)   

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