KEGG   Equus caballus (horse): 100068678
Entry
100068678         CDS       T01058                                 
Symbol
BCKDHA
Name
(RefSeq) 2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial isoform X4
  KO
K00166  2-oxoisovalerate dehydrogenase E1 component subunit alpha [EC:1.2.4.4]
Organism
ecb  Equus caballus (horse)
Pathway
ecb00280  Valine, leucine and isoleucine degradation
ecb00640  Propanoate metabolism
ecb00785  Lipoic acid metabolism
ecb01100  Metabolic pathways
ecb01210  2-Oxocarboxylic acid metabolism
Module
ecb_M00036  Leucine degradation, leucine => acetoacetate + acetyl-CoA
Brite
KEGG Orthology (KO) [BR:ecb00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00640 Propanoate metabolism
    100068678 (BCKDHA)
  09105 Amino acid metabolism
   00280 Valine, leucine and isoleucine degradation
    100068678 (BCKDHA)
  09108 Metabolism of cofactors and vitamins
   00785 Lipoic acid metabolism
    100068678 (BCKDHA)
Enzymes [BR:ecb01000]
 1. Oxidoreductases
  1.2  Acting on the aldehyde or oxo group of donors
   1.2.4  With a disulfide as acceptor
    1.2.4.4  3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
     100068678 (BCKDHA)
SSDB
Motif
Pfam: E1_dh TPP_enzyme_C DXP_synthase_N
Other DBs
NCBI-GeneID: 100068678
NCBI-ProteinID: XP_001500344
Ensembl: ENSECAG00000012246
Position
10:12066726..12084522
AA seq 445 aa
MAVVTAAARVLGSSRGLGQDGLLLLRRLGVRGLAISHPQRQQQRFSSLDDKPQFPGASAE
FIDKLEFIQPNVISGIPIYRVMDRQGQIINPSEDPNLPQEKVLKFYKSMTLLNTMDRILY
ESQRQGRISFYMTNYGEEGTHVGSAAALDNTDLVFGQYREAGVLMYRDYPLELFMAQCYG
NVSDLGKGRQMPVHYGCKERHFVTISSPLATQIPQAVGAAYAAKRANANRVVICYFGEGA
ASEGDAHAGFNFAATLECPIIFFCRNNGYAISTPTSEQYRGDGIAARGPGYGIMSIRVDG
NDVFAVYNATKEARRRAVAENQPFLIEAMTYRIGHHSTSDDSSAYRSVDEVNYWDKQDHP
ISRLRHYLQSRGWWDDEQEKDWRKQSRKKVMEAFEQAERKPKPNFSLLFSDVYQEMPAQL
RKQQESLARHLQTYGEHYPLDHFEK
NT seq 1338 nt   +upstreamnt  +downstreamnt
atggcggtggtgacagctgcggcgagagtcctgggatcaagtagaggcctgggccaggat
ggcctactgctcttgcggcggcttggggttcgggggctggctatatctcacccccagagg
cagcagcagcgcttctcgtccttggatgacaagccccagttcccaggggcctcagcggag
tttatagacaagctagagttcatccagcctaatgtcatctctgggatccccatctaccgc
gtcatggaccggcagggccagatcatcaaccccagcgaggaccccaatctgccccaggag
aaggtgctcaagttctacaagagcatgacactgctcaacaccatggaccgcatcctctac
gagtcccagcggcagggccggatctccttctacatgaccaactatggcgaggaggggaca
cacgtggggagtgcagcagccctggacaacacggacctggtgtttggccagtaccgggag
gcaggtgtgctgatgtatcgggactaccccctggaactgttcatggcccagtgctacggc
aacgtgagtgacctgggcaaggggcgccagatgcccgtccactatggctgcaaggagcgc
cactttgtcaccatctcctctccactggccacgcagatccctcaggcggtgggggcggcc
tacgcggccaagcgggccaatgccaacagggtcgtcatctgttactttggtgagggggcg
gccagtgagggagatgcccacgccggcttcaacttcgccgccaccctcgagtgccccatc
atcttcttctgccggaacaacggctatgccatctccacacccacttctgagcagtaccgc
ggggatggcatcgcggctcgaggccccgggtatggcatcatgtcaatccgcgtggacggc
aatgatgtgtttgctgtgtacaacgccaccaaggaggcccggcggcgtgccgtggcagag
aaccagcccttcctcattgaggccatgacctacaggatcgggcaccatagcaccagtgac
gatagctcagcgtaccgctctgtggacgaggtcaattactgggacaagcaggaccacccc
atctcgcggctgaggcactacctgcagagccgtggctggtgggatgatgagcaggagaag
gactggaggaagcagtctcgtaagaaggtgatggaggcctttgagcaggctgagcggaag
ccgaagcccaacttcagcctgctcttctcagatgtgtatcaggagatgcccgcccagctc
cgcaagcagcaggagtccctggcccgtcacctccagacctatggcgagcactaccccctg
gaccacttcgagaagtga

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (6)   
   KEGG PATHWAY (5)   
   KEGG MODULE (1)   
Chemical substance (22)   
   KEGG COMPOUND (22)   
Chemical reaction (15)   
   KEGG ENZYME (1)   
   KEGG REACTION (14)   
Genome (1)   
   KEGG GENOME (1)   
Gene (26)   
   KEGG ORTHOLOGY (1)   
   RefGene (21)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (4)   
   RefSeq(pep) (4)   
DNA sequence (4)   
   RefSeq(nuc) (4)   
Protein domain (3)   
   Pfam (3)   
All databases (83)   

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