KEGG   Escherichia coli K-12 MG1655: b0570
Entry
b0570             CDS       T00007                                 
Symbol
cusS
Name
(RefSeq) sensor histidine kinase CusS
  KO
K07644  two-component system, OmpR family, heavy metal sensor histidine kinase CusS [EC:2.7.13.3]
Organism
eco  Escherichia coli K-12 MG1655
Pathway
eco02020  Two-component system
Brite
KEGG Orthology (KO) [BR:eco00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   02020 Two-component system
    b0570 (cusS)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:eco01001]
    b0570 (cusS)
  09183 Protein families: signaling and cellular processes
   02022 Two-component system [BR:eco02022]
    b0570 (cusS)
   01504 Antimicrobial resistance genes [BR:eco01504]
    b0570 (cusS)
Enzymes [BR:eco01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.13  Protein-histidine kinases
    2.7.13.3  histidine kinase
     b0570 (cusS)
Protein kinases [BR:eco01001]
 Histidine kinases
  OmpR family
   b0570 (cusS)
Two-component system [BR:eco02022]
 OmpR family
  CusS-CusR (copper tolerance)
   b0570 (cusS)
Antimicrobial resistance genes [BR:eco01504]
 Gene sets
  beta-Lactam resistance modules
   Imipenem resistance, repression of porin OprD [MD:M00745]
    b0570 (cusS)
SSDB
Motif
Pfam: CusS HATPase_c HisKA HAMP HATPase_c_5 HATPase_c_2 DUF5337
Other DBs
NCBI-GeneID: 945978
NCBI-ProteinID: NP_415102
Pasteur: ybcZ
RegulonDB: ECK120002926
ECOCYC: G6318
ASAP: ABE-0001946
UniProt: P77485
Structure
Position
complement(593328..594770)
AA seq 480 aa
MVSKPFQRPFSLATRLTFFISLATIAAFFAFAWIMIHSVKVHFAEQDINDLKEISATLER
VLNHPDETQARRLMTLEDIVSGYSNVLISLADSQGKTVYHSPGAPDIREFTRDAIPDKDA
QGGEVYLLSGPTMMMPGHGHGHMEHSNWRMINLPVGPLVDGKPIYTLYIALSIDFHLHYI
NDLMNKLIMTASVISILIVFIVLLAVHKGHAPIRSVSRQIQNITSKDLDVRLDPQTVPIE
LEQLVLSFNHMIERIEDVFTRQSNFSADIAHEIRTPITNLITQTEIALSQSRSQKELEDV
LYSNLEELTRMAKMVSDMLFLAQADNNQLIPEKKMLNLADEVGKVFDFFEALAEDRGVEL
RFVGDKCQVAGDPLMLRRALSNLLSNALRYTPTGETIVVRCQTVDHLVQVIVENPGTPIA
PEHLPRLFDRFYRVDPSRQRKGEGSGIGLAIVKSIVVAHKGTVAVTSDARGTRFVITLPA
NT seq 1443 nt   +upstreamnt  +downstreamnt
atggtcagtaagccatttcagcgcccgttttcgctggcaacccgcctgaccttttttatc
agcctggccaccatcgcggcgtttttcgcctttgcatggatcatgatccactcagtaaaa
gttcattttgccgagcaggatattaatgatttaaaagagattagcgccacccttgaacgg
gtactaaatcaccctgacgaaacgcaagcccgacgcttaatgacgctggaagatatcgtc
agtggttattccaatgtgttgatttccctggcagatagtcagggtaaaacggtgtatcac
tcccccggtgcgccggatatccgcgagtttacgcgtgacgccatacccgataaagacgct
cagggtggcgaggtgtatctcctttccggcccgacgatgatgatgccaggccacggtcac
gggcatatggaacacagcaactggcggatgattaacttgccggttggcccgttggtggac
ggcaaaccgatttatacgctctacatcgcgctttcgatcgattttcatcttcattacata
aatgatttgatgaataaacttattatgaccgcatcggtaatcagcatcctgatcgtcttt
atcgtactgttggcggtacataaaggtcacgcgccgatccgcagcgtcagccgtcaaatc
cagaatattacctcgaaagatctcgacgttcgcctcgacccgcagaccgtgcccattgag
ctggaacagctggtactgtcgttcaaccatatgatcgagcgtattgaggatgtctttacc
cgccagtccaatttctcagcggatatcgctcacgaaattcgcacaccaattacgaatctc
ataacgcaaaccgaaatcgccctcagccagtcgcgcagccagaaggagctggaagatgtg
ctctactctaatctcgaagagctgacgcgaatggcgaaaatggtcagcgatatgctgttt
ctcgctcaggccgataacaaccagctaatccccgaaaagaaaatgctcaacctggcggat
gaagtcggcaaagtgttcgattttttcgaggcgttagcggaagatcgcggcgtggagttg
cggtttgttggcgacaagtgtcaggtcgcgggcgatccgctgatgctgcgtcgggcgcta
agcaacctgctttcgaacgccctgcgttatacgccaaccggagagacaattgtagtgcgc
tgtcagacggtcgatcacctggtgcaagttatcgtcgaaaaccccggtacgcccattgcg
cccgagcacttaccgcgattgtttgaccgtttctatcgcgttgacccctcccgccagcga
aaaggtgaaggtagcggtattggcctggcgatagtgaaatcgattgttgtcgcgcataaa
ggcacggttgcggtaacgtcggatgcgcgggggacaaggtttgttatcacattacccgct
taa

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Ontology (5)   
   KEGG BRITE (5)   
Pathway (2)   
   KEGG PATHWAY (1)   
   KEGG MODULE (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (16)   
   KEGG ORTHOLOGY (1)   
   RefGene (8)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   ASAP (1)   
   ECOCYC (1)   
   OC (1)   
   PASTEUR (1)   
   REGULONDB (1)   
Protein sequence (3)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
3D Structure (1)   
   PDB (1)   
Protein domain (7)   
   Pfam (7)   
All databases (36)   

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