KEGG   Escherichia coli K-12 MG1655: b0529
Entry
b0529             CDS       T00007                                 
Symbol
folD
Name
(RefSeq) bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase
  KO
K01491  methylenetetrahydrofolate dehydrogenase (NADP+) / methenyltetrahydrofolate cyclohydrolase [EC:1.5.1.5 3.5.4.9]
Organism
eco  Escherichia coli K-12 MG1655
Pathway
eco00670  One carbon pool by folate
eco01100  Metabolic pathways
eco01120  Microbial metabolism in diverse environments
eco01200  Carbon metabolism
eco01240  Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:eco00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    b0529 (folD)
Enzymes [BR:eco01000]
 1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.5  methylenetetrahydrofolate dehydrogenase (NADP+)
     b0529 (folD)
 3. Hydrolases
  3.5  Acting on carbon-nitrogen bonds, other than peptide bonds
   3.5.4  In cyclic amidines
    3.5.4.9  methenyltetrahydrofolate cyclohydrolase
     b0529 (folD)
SSDB
Motif
Pfam: THF_DHG_CYH_C THF_DHG_CYH
Other DBs
NCBI-GeneID: 945221
NCBI-ProteinID: NP_415062
Pasteur: folD
RegulonDB: ECK120000322
ECOCYC: EG10328
ASAP: ABE-0001818
UniProt: P24186
Structure
Position
complement(556875..557741)
AA seq 288 aa
MAAKIIDGKTIAQQVRSEVAQKVQARIAAGLRAPGLAVVLVGSNPASQIYVASKRKACEE
VGFVSRSYDLPETTSEAELLELIDTLNADNTIDGILVQLPLPAGIDNVKVLERIHPDKDV
DGFHPYNVGRLCQRAPRLRPCTPRGIVTLLERYNIDTFGLNAVVIGASNIVGRPMSMELL
LAGCTTTVTHRFTKNLRHHVENADLLIVAVGKPGFIPGDWIKEGAIVIDVGINRLENGKV
VGDVVFEDAAKRASYITPVPGGVGPMTVATLIENTLQACVEYHDPQDE
NT seq 867 nt   +upstreamnt  +downstreamnt
atggcagcaaagattattgacggtaaaacgattgcgcagcaggtgcgctctgaagttgct
caaaaagttcaggcgcgtattgcagccggactgcgggcaccaggactggccgttgtgctg
gtgggtagtaaccctgcatcgcaaatttatgtcgcaagcaaacgcaaggcttgtgaagaa
gtcgggttcgtctcccgctcttatgacctcccggaaaccaccagcgaagcggagctgctg
gagcttatcgatacgctgaatgccgacaacaccatcgatggcattctggttcaactgccg
ttaccggcgggtattgataacgtcaaagtgctggaacgtattcatccggacaaagacgtg
gacggtttccatccttacaacgtcggtcgtctgtgccagcgcgcgccgcgtctgcgtccc
tgcaccccgcgcggtatcgtcacgctgcttgagcgttacaacattgataccttcggcctc
aacgccgtggtgattggcgcatcgaatatcgttggccgcccgatgagcatggaactgctg
ctggcaggttgcaccactacagtgactcaccgcttcactaaaaatctgcgtcatcacgta
gaaaatgccgatctattgatcgttgccgttggcaagccaggctttattcccggtgactgg
atcaaagaaggcgcaattgtgattgatgtcggcatcaaccgtctggaaaatggcaaagtt
gtgggcgacgtcgtgtttgaagacgcggctaaacgcgcctcatacattacgcctgttccc
ggcggcgttggcccgatgacggttgccacgctgattgaaaacacgctacaggcgtgcgtt
gaatatcatgatccacaggatgagtaa

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (7)   
   KEGG PATHWAY (5)   
   KEGG MODULE (2)   
Chemical substance (7)   
   KEGG COMPOUND (7)   
Chemical reaction (4)   
   KEGG ENZYME (2)   
   KEGG REACTION (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (10)   
   KEGG ORTHOLOGY (1)   
   RefGene (2)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   ASAP (1)   
   ECOCYC (1)   
   OC (1)   
   PASTEUR (1)   
   REGULONDB (1)   
Protein sequence (3)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
3D Structure (4)   
   PDB (4)   
Protein domain (2)   
   Pfam (2)   
All databases (40)   

Download RDF
DBGET integrated database retrieval system