KEGG   Escherichia coli K-12 MG1655: b0726
Entry
b0726             CDS       T00007                                 
Symbol
sucA
Name
(RefSeq) subunit of E1(0) component of 2-oxoglutarate dehydrogenase
  KO
K00164  2-oxoglutarate dehydrogenase E1 component [EC:1.2.4.2]
Organism
eco  Escherichia coli K-12 MG1655
Pathway
eco00020  Citrate cycle (TCA cycle)
eco00785  Lipoic acid metabolism
eco01100  Metabolic pathways
eco01110  Biosynthesis of secondary metabolites
eco01120  Microbial metabolism in diverse environments
eco01200  Carbon metabolism
eco01210  2-Oxocarboxylic acid metabolism
Module
eco_M00009  Citrate cycle (TCA cycle, Krebs cycle)
eco_M00011  Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
Brite
KEGG Orthology (KO) [BR:eco00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00020 Citrate cycle (TCA cycle)
    b0726 (sucA)
  09108 Metabolism of cofactors and vitamins
   00785 Lipoic acid metabolism
    b0726 (sucA)
Enzymes [BR:eco01000]
 1. Oxidoreductases
  1.2  Acting on the aldehyde or oxo group of donors
   1.2.4  With a disulfide as acceptor
    1.2.4.2  oxoglutarate dehydrogenase (succinyl-transferring)
     b0726 (sucA)
SSDB
Motif
Pfam: OxoGdeHyase_C Transket_pyr E1_dh 2-oxogl_dehyd_N PFOR_II
Other DBs
NCBI-GeneID: 945303
NCBI-ProteinID: NP_415254
Pasteur: sucA
RegulonDB: ECK120000968
ECOCYC: EG10979
ASAP: ABE-0002478
UniProt: P0AFG3
Structure
Position
758706..761507
AA seq 933 aa
MQNSALKAWLDSSYLSGANQSWIEQLYEDFLTDPDSVDANWRSTFQQLPGTGVKPDQFHS
QTREYFRRLAKDASRYSSTISDPDTNVKQVKVLQLINAYRFRGHQHANLDPLGLWQQDKV
ADLDPSFHDLTEADFQETFNVGSFASGKETMKLGELLEALKQTYCGPIGAEYMHITSTEE
KRWIQQRIESGRATFNSEEKKRFLSELTAAEGLERYLGAKFPGAKRFSLEGGDALIPMLK
EMIRHAGNSGTREVVLGMAHRGRLNVLVNVLGKKPQDLFDEFAGKHKEHLGTGDVKYHMG
FSSDFQTDGGLVHLALAFNPSHLEIVSPVVIGSVRARLDRLDEPSSNKVLPITIHGDAAV
TGQGVVQETLNMSKARGYEVGGTVRIVINNQVGFTTSNPLDARSTPYCTDIGKMVQAPIF
HVNADDPEAVAFVTRLALDFRNTFKRDVFIDLVCYRRHGHNEADEPSATQPLMYQKIKKH
PTPRKIYADKLEQEKVATLEDATEMVNLYRDALDAGDCVVAEWRPMNMHSFTWSPYLNHE
WDEEYPNKVEMKRLQELAKRISTVPEAVEMQSRVAKIYGDRQAMAAGEKLFDWGGAENLA
YATLVDEGIPVRLSGEDSGRGTFFHRHAVIHNQSNGSTYTPLQHIHNGQGAFRVWDSVLS
EEAVLAFEYGYATAEPRTLTIWEAQFGDFANGAQVVIDQFISSGEQKWGRMCGLVMLLPH
GYEGQGPEHSSARLERYLQLCAEQNMQVCVPSTPAQVYHMLRRQALRGMRRPLVVMSPKS
LLRHPLAVSSLEELANGTFLPAIGEIDELDPKGVKRVVMCSGKVYYDLLEQRRKNNQHDV
AIVRIEQLYPFPHKAMQEVLQQFAHVKDFVWCQEEPLNQGAWYCSQHHFREVIPFGASLR
YAGRPASASPAVGYMSVHQKQQQDLVNDALNVE
NT seq 2802 nt   +upstreamnt  +downstreamnt
atgcagaacagcgctttgaaagcctggttggactcttcttacctctctggcgcaaaccag
agctggatagaacagctctatgaagacttcttaaccgatcctgactcggttgacgctaac
tggcgttcgacgttccagcagttacctggtacgggagtcaaaccggatcaattccactct
caaacgcgtgaatatttccgccgcctggcgaaagacgcttcacgttactcttcaacgatc
tccgaccctgacaccaatgtgaagcaggttaaagtcctgcagctcattaacgcataccgc
ttccgtggtcaccagcatgcgaatctcgatccgctgggactgtggcagcaagataaagtg
gccgatctggatccgtctttccacgatctgaccgaagcagacttccaggagaccttcaac
gtcggttcatttgccagcggcaaagaaaccatgaaactcggcgagctgctggaagccctc
aagcaaacctactgcggcccgattggtgccgagtatatgcacattaccagcaccgaagaa
aaacgctggatccaacagcgtatcgagtctggtcgcgcgactttcaatagcgaagagaaa
aaacgcttcttaagcgaactgaccgccgctgaaggtcttgaacgttacctcggcgcaaaa
ttccctggcgcaaaacgcttctcgctggaaggcggtgacgcgttaatcccgatgcttaaa
gagatgatccgccacgctggcaacagcggcacccgcgaagtggttctcgggatggcgcac
cgtggtcgtctgaacgtgctggtgaacgtgctgggtaaaaaaccgcaagacttgttcgac
gagttcgccggtaaacataaagaacacctcggcacgggtgacgtgaaataccacatgggc
ttctcgtctgacttccagaccgatggcggcctggtgcacctggcgctggcgtttaacccg
tctcaccttgagattgtaagcccggtagttatcggttctgttcgtgcccgtctggacaga
cttgatgagccgagcagcaacaaagtgctgccaatcaccatccacggtgacgccgcagtg
accgggcagggcgtggttcaggaaaccctgaacatgtcgaaagcgcgtggttatgaagtt
ggcggtacggtacgtatcgttatcaacaaccaggttggtttcaccacctctaatccgctg
gatgcccgttctacgccgtactgtactgatatcggtaagatggttcaggccccgattttc
cacgttaacgcggacgatccggaagccgttgcctttgtgacccgtctggcgctcgatttc
cgtaacacctttaaacgtgatgtcttcatcgacctggtgtgctaccgccgtcacggccac
aacgaagccgacgagccgagcgcaacccagccgctgatgtatcagaaaatcaaaaaacat
ccgacaccgcgcaaaatctacgctgacaagctggagcaggaaaaagtggcgacgctggaa
gatgccaccgagatggttaacctgtaccgcgatgcgctggatgctggcgattgcgtagtg
gcagagtggcgtccgatgaacatgcactctttcacctggtcgccgtacctcaaccacgaa
tgggacgaagagtacccgaacaaagttgagatgaagcgcctgcaggagctggcgaaacgc
atcagcacggtgccggaagcagttgaaatgcagtctcgcgttgccaagatttatggcgat
cgccaggcgatggctgccggtgagaaactgttcgactggggcggtgcggaaaacctcgct
tacgccacgctggttgatgaaggcattccggttcgcctgtcgggtgaagactccggtcgc
ggtaccttcttccaccgccacgcggtgatccacaaccagtctaacggttccacttacacg
ccgctgcaacatatccataacgggcagggcgcgttccgtgtctgggactccgtactgtct
gaagaagcagtgctggcgtttgaatatggttatgccaccgcagaaccacgcactctgacc
atctgggaagcgcagttcggtgacttcgccaacggtgcgcaggtggttatcgaccagttc
atctcctctggcgaacagaaatggggccggatgtgtggtctggtgatgttgctgccgcac
ggttacgaagggcaggggccggagcactcctccgcgcgtctggaacgttatctgcaactt
tgtgctgagcaaaacatgcaggtttgcgtaccgtctaccccggcacaggtttaccacatg
ctgcgtcgtcaggcgctgcgcgggatgcgtcgtccgctggtcgtgatgtcgccgaaatcc
ctgctgcgtcatccgctggcggtttccagcctcgaagaactggcgaacggcaccttcctg
ccagccatcggtgaaatcgacgagcttgatccgaagggcgtgaagcgcgtagtgatgtgt
tctggtaaggtttattacgacctgctggaacagcgtcgtaagaacaatcaacacgatgtc
gccattgtgcgtatcgagcaactctacccgttcccgcataaagcgatgcaggaagtgttg
cagcagtttgctcacgtcaaggattttgtctggtgccaggaagagccgctcaaccagggc
gcatggtactgcagccagcatcatttccgtgaagtgattccgtttggggcttctctgcgt
tatgcaggccgcccggcctccgcctctccggcggtagggtatatgtccgttcaccagaaa
cagcaacaagatctggttaatgacgcgctgaacgtcgaataa

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (9)   
   KEGG PATHWAY (7)   
   KEGG MODULE (2)   
Chemical substance (11)   
   KEGG COMPOUND (11)   
Chemical reaction (5)   
   KEGG ENZYME (1)   
   KEGG REACTION (4)   
Genome (1)   
   KEGG GENOME (1)   
Gene (14)   
   KEGG ORTHOLOGY (1)   
   RefGene (6)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   ASAP (1)   
   ECOCYC (1)   
   OC (1)   
   PASTEUR (1)   
   REGULONDB (1)   
Protein sequence (3)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
3D Structure (2)   
   PDB (2)   
Protein domain (5)   
   Pfam (5)   
All databases (52)   

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