KEGG   Escherichia coli O25b K100 H4-ST131 EC958 (UPEC): EC958_A0108
Entry
EC958_A0108       CDS       T04373                                 
Symbol
dfrA17
Name
(GenBank) type 1 dihydrofolate reductase
  KO
K18589  dihydrofolate reductase (trimethoprim resistance protein) [EC:1.5.1.3]
Organism
ecos  Escherichia coli O25b:K100:H4-ST131 EC958 (UPEC)
Pathway
ecos00670  One carbon pool by folate
ecos00790  Folate biosynthesis
ecos01100  Metabolic pathways
Brite
KEGG Orthology (KO) [BR:ecos00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00790 Folate biosynthesis
    EC958_A0108 (dfrA17)
   00670 One carbon pool by folate
    EC958_A0108 (dfrA17)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   01504 Antimicrobial resistance genes [BR:ecos01504]
    EC958_A0108 (dfrA17)
Enzymes [BR:ecos01000]
 1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.3  dihydrofolate reductase
     EC958_A0108 (dfrA17)
Antimicrobial resistance genes [BR:ecos01504]
 Gene variants
  Trimethoprim resistance genes
   Dihydrofolate reductases
    EC958_A0108 (dfrA17)
SSDB
Motif
Pfam: DHFR_1
Other DBs
NCBI-ProteinID: CDN85454
UniProt: A0AA36L5N8
Position
pEC958:88981..89454
AA seq 157 aa
MKISLISAVSENGVIGSGPDIPWSVKGEQLLFKALTYNQWLLVGRKTFDSMGVLPNRKYA
VVSKNGISSSNENVLVFPSIENALKELSKVTDHVYVSGGGQIYNSLIEKADIIHLSTVHV
EVEGDIKFPIMPENFNLVFEQFFMSNINYTYQIWKKG
NT seq 474 nt   +upstreamnt  +downstreamnt
ttgaaaatatcattgatttctgcagtgtcagaaaatggcgtaatcggtagtggtcctgat
atcccgtggtcagtaaaaggtgagcaactactctttaaagcgctcacatataatcaatgg
ctccttgtcggaagaaaaacatttgactctatgggtgttcttccaaatcgcaaatatgca
gtagtgtcaaagaacggaatttcaagctcaaatgaaaacgtcctagtttttccttcaata
gaaaatgctttgaaagagctatcaaaagttacagatcatgtatatgtctctggcgggggt
caaatctataatagccttattgaaaaagcagatataattcatttgtctactgttcacgtt
gaagtcgaaggtgatatcaaattccctataatgcctgagaatttcaatttggtttttgaa
cagttttttatgtctaatataaattatacataccagatttggaaaaaaggctaa

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (3)   
   KEGG PATHWAY (3)   
Chemical substance (8)   
   KEGG COMPOUND (8)   
Chemical reaction (7)   
   KEGG ENZYME (1)   
   KEGG REACTION (6)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein sequence (1)   
   UniProt (1)   
Protein domain (1)   
   Pfam (1)   
All databases (27)   

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