KEGG   Escherichia coli O8 IAI1 (commensal): ECIAI1_3818
Entry
ECIAI1_3818       CDS       T00828                                 
Symbol
ligB
Name
(GenBank) DNA ligase, NAD(+)-dependent
  KO
K01972  DNA ligase (NAD+) [EC:6.5.1.2]
Organism
ecr  Escherichia coli O8 IAI1 (commensal)
Pathway
ecr03030  DNA replication
ecr03410  Base excision repair
ecr03420  Nucleotide excision repair
ecr03430  Mismatch repair
Brite
KEGG Orthology (KO) [BR:ecr00001]
 09120 Genetic Information Processing
  09124 Replication and repair
   03030 DNA replication
    ECIAI1_3818 (ligB)
   03410 Base excision repair
    ECIAI1_3818 (ligB)
   03420 Nucleotide excision repair
    ECIAI1_3818 (ligB)
   03430 Mismatch repair
    ECIAI1_3818 (ligB)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03032 DNA replication proteins [BR:ecr03032]
    ECIAI1_3818 (ligB)
   03400 DNA repair and recombination proteins [BR:ecr03400]
    ECIAI1_3818 (ligB)
Enzymes [BR:ecr01000]
 6. Ligases
  6.5  Forming phosphoric-ester bonds
   6.5.1  Ligases that form phosphoric-ester bonds (only sub-subclass identified to date)
    6.5.1.2  DNA ligase (NAD+)
     ECIAI1_3818 (ligB)
DNA replication proteins [BR:ecr03032]
 Prokaryotic type
  DNA Replication Elongation Factors
   Elongation factors (bacterial)
    Other elongation factors
     ECIAI1_3818 (ligB)
DNA repair and recombination proteins [BR:ecr03400]
 Prokaryotic type
  SSBR (single strand breaks repair)
   BER (base exicision repair)
    DNA ligase
     ECIAI1_3818 (ligB)
   NER (nucleotide excision repair)
    GGR (global genome repair) factors
     ECIAI1_3818 (ligB)
   MMR (mismatch excision repair)
    DNA ligase
     ECIAI1_3818 (ligB)
  DSBR (double strand breaks repair)
   NHEJ (non-homologous end-joining)
    SHDIR (short-homology-dependent illegitimate recombination)
     RecET pathway
      ECIAI1_3818 (ligB)
SSDB
Motif
Pfam: DNA_ligase_aden DNA_ligase_OB RNA_ligase
Other DBs
NCBI-ProteinID: CAR00615
UniProt: B7M4D2
Position
complement(3889950..3891632)
AA seq 560 aa
MKVWMAILISILCWQSSVWAVCPAWSPARAQEEISRLQQQIKQWDDDYWKEGKSEVEDGV
YDQLSARLTQWQRCFGSEPRDVMMPPLNGAVMHPVAHTGVRKMVDKNALSLWMRERSDLW
VQPKVDGVAVTLVYRDGKLNKAISRGNGLKGEDWTQKVSLISAVPQTVSGPLANSTLQGE
IFLQREGHIQQQMGGINARAKVAGLMMRQDDSDTLNSLGVFVWAWPDGPQLMSDRLKELA
TAGFTLTQTYTRAVKNADEVARVRNEWWKAELPFVTDGVVVRGAKEPESRHWLPGQAEWL
VAWKYQPVAQVAEVKAIQFAVGKSGKISVVASLAPVMLDDKKVQRVNIGSVRRWQEWDIA
PGDQILVSLAGQGIPRIDDVVWRGAERTKPTPPENRFNSLTCYFASDVCQEQFISRLVWL
GSKQVLGLDGIGEAGWRALHQTHRFEHIFSWLLLTPEQLQNTPGIAKSKSAQLWHQFNLA
RKQPFTRWVMAMGIPLTRAALNASDERSWSQLLFSTEQFWQQLPGTGSGRARQVIEWKEN
AQIKKLGSWLAAQQITGFEP
NT seq 1683 nt   +upstreamnt  +downstreamnt
atgaaagtatggatggcgatattaataagtatcttgtgctggcaatcatctgtgtgggcg
gtctgtccggcctggtcgccagccagagcacaggaagaaatttcccgcctgcaacagcaa
ataaaacagtgggacgatgactactggaaggaaggaaaaagtgaggtggaagacggtgtt
tacgatcagttaagcgcccgtcttacgcagtggcaacgctgctttgggagcgagccccgc
gacgtgatgatgccgcctttaaatggtgcggttatgcatccggttgcccatacgggtgta
cgcaaaatggtggataaaaacgcattaagtctgtggatgcgagaacgtagcgatctttgg
gtgcagccaaaagttgatggcgttgcggtaaccctggtttatcgggacgggaaactgaac
aaagcaatcagtcgcggtaatggcctgaaaggcgaggactggacgcagaaagttagctta
atttccgctgtgccgcaaaccgttagcgggcctttagccaacagtacgcttcagggggaa
atatttctccagcgcgaggggcatatccaacaacaaatggggggaataaatgcccgcgca
aaagttgctggcttgatgatgcgccaggacgatagcgacacgctgaattctctgggcgtt
tttgtctgggcatggccggatggaccgcagttaatgtctgatcgtttaaaagagctggct
accgcaggttttactctaacgcagacgtatacccgtgcggtgaaaaatgctgatgaagtt
gcgcgcgtacgcaatgagtggtggaaagcggaattacccttcgtcaccgatggcgtagtt
gtgcgaggggcgaaagaacccgaatcccgccattggctaccaggccaggcagaatggctg
gtggcctggaaatatcaacctgtagctcaggttgccgaagtgaaggcgattcagtttgcg
gtgggtaagagcggtaaaatatcggtggttgcgtcactcgcacctgtcatgctggatgat
aaaaaagtccagcgggtgaatattggttccgtcaggcgctggcaggagtgggatattgcg
cctggtgatcagatcctcgtcagccttgccggtcagggtattcctcgcattgatgatgtg
gtctggcgcggtgcagaacgtacaaaaccgacaccaccagaaaaccgctttaactcgttg
acctgctactttgcttctgatgtttgtcaggaacagttcatttcacgcttagtctggctg
gggtcaaaacaggttctggggctggatggcattggtgaggccggctggcgcgcgctgcat
cagactcatcgctttgagcatatcttttcctggcttttattaacgccagagcaattacag
aacacgccggggatcgcgaaaagtaaaagtgcgcagctatggcatcagtttaatctggct
cgtaagcagccttttactcgctgggtgatggcaatgggaataccgctaacccgggcggcg
cttaatgccagtgatgaacggtcctggtcgcaacttttatttagcacggagcagttctgg
cagcagctgccggggactggatcggggcgcgccagacaggttattgaatggaaggaaaat
gcgcaaatcaagaagctgggcagttggctggctgcccagcagatcacaggttttgaacct
tag

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Ontology (4)   
   KEGG BRITE (4)   
Pathway (4)   
   KEGG PATHWAY (4)   
Chemical substance (5)   
   KEGG COMPOUND (5)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein sequence (2)   
   UniProt (1)   
   SWISS-PROT (1)   
Protein domain (3)   
   Pfam (3)   
All databases (24)   

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