KEGG   Escherichia coli O18 K1 H7 IHE3034 (ExPEC): ECOK1_4221
Entry
ECOK1_4221        CDS       T01997                                 
Symbol
ilvC
Name
(GenBank) ketol-acid reductoisomerase
  KO
K00053  ketol-acid reductoisomerase [EC:1.1.1.86]
Organism
eih  Escherichia coli O18:K1:H7 IHE3034 (ExPEC)
Pathway
eih00290  Valine, leucine and isoleucine biosynthesis
eih00770  Pantothenate and CoA biosynthesis
eih01100  Metabolic pathways
eih01110  Biosynthesis of secondary metabolites
eih01210  2-Oxocarboxylic acid metabolism
eih01230  Biosynthesis of amino acids
Module
eih_M00019  Valine/isoleucine biosynthesis, pyruvate => valine / 2-oxobutanoate => isoleucine
eih_M00570  Isoleucine biosynthesis, threonine => 2-oxobutanoate => isoleucine
Brite
KEGG Orthology (KO) [BR:eih00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00290 Valine, leucine and isoleucine biosynthesis
    ECOK1_4221 (ilvC)
  09108 Metabolism of cofactors and vitamins
   00770 Pantothenate and CoA biosynthesis
    ECOK1_4221 (ilvC)
Enzymes [BR:eih01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.86  ketol-acid reductoisomerase (NADP+)
     ECOK1_4221 (ilvC)
SSDB
Motif
Pfam: IlvN IlvC 2-Hacid_dh_C NAD_binding_7 ApbA AdoHcyase_NAD F420_oxidored Sacchrp_dh_NADP
Other DBs
NCBI-ProteinID: ADE89896
Position
4331680..4333155
AA seq 491 aa
MANYFNTLNLRQQLAQLGKCRFMGRDEFADGASYLQGKKVVIVGCGAQGLNQGLNMRDSG
LDISYALRKEAIAEKRASWRKATENGFKVGTYEELIPQADLVVNLTPDKQHSDVVRSVQP
LMKDGAALGYSHGFNIVEVGEQIRKDITVVMVAPKCPGTEVREEYKRGFGVPTLIAVHPE
NDPKGEGMAIAKAWAAATGGHRAGVLESSFVAEVKSDLMGEQTILCGMLQAGSLLCFDKL
VEEGTDPAYAEKLIQFGWETITEALKQGGITLMMDRLSNPAKLRAYALSEQLKEIMAPLF
QKHMDDIISGEFSSGMMADWANDDKKLLTWREETGKTAFETAPQYEGKIGEQEYFDKGVL
MIAMVKAGVELAFETMVDSGIIEESAYYESLHELPLIANTIARKRLYEMNVVISDTAEYG
NYLFSYACVPLLKPFMAELQPGDLGKAIPEGAVDNAQLRDVNEAIRSHAIEQVGKKLRGY
MTDMKRIAVAG
NT seq 1476 nt   +upstreamnt  +downstreamnt
atggctaactacttcaatacactgaatctgcgccagcagttggcacagctgggcaaatgt
cgctttatggggcgcgatgaattcgccgatggcgcgagctaccttcagggtaaaaaagta
gtcatcgtcggctgtggtgcacagggtctgaaccagggcctgaacatgcgtgattctggt
ctcgatatctcctacgctctgcgtaaagaagcgattgccgagaagcgcgcatcctggcgt
aaagcgaccgaaaacggcttcaaagttggcacttacgaagaactgatcccgcaggcggat
ctggtggttaacctgacgccagacaagcagcactctgacgtagtgcgttccgttcagccg
ctgatgaaagacggcgcggcgctgggctactctcatggtttcaatatcgtagaagtgggt
gagcagatccgtaaagacatcaccgtcgtaatggttgcgccgaaatgccctggcaccgaa
gtacgtgaagagtacaaacgtggattcggcgtaccgacgctgattgccgttcacccggaa
aacgatccgaaaggcgaaggcatggcgatcgctaaagcatgggcggctgcaaccggcggt
caccgtgcgggcgttctggaatcctctttcgttgcggaagtgaaatctgacctgatgggc
gagcaaaccatcctgtgcggtatgttgcaagctggttctctgctgtgcttcgacaagctg
gtggaagaaggcaccgatccggcatacgcagaaaaactgattcagttcggttgggaaacc
atcaccgaagcgctgaaacagggcggcatcaccctgatgatggaccgtctttctaacccg
gcgaaactgcgtgcttacgcgctctctgagcaattgaaagagatcatggcgccgctgttc
cagaaacatatggacgacatcatctccggcgaattctcctccggcatgatggctgactgg
gccaacgacgataagaaactgctgacctggcgtgaagagactggcaaaaccgcattcgaa
accgcgccgcagtatgaaggcaaaatcggcgaacaggagtacttcgataaaggcgtactg
atgatcgcgatggtaaaagcaggcgttgagttggcgtttgaaaccatggttgattccggc
atcatcgaagaatctgcttactatgaatcactgcacgaactgccgctgattgccaacacc
atcgcccgtaagcgtctgtacgaaatgaacgtggttatctccgatactgccgagtacggt
aactatctgttctcttacgcttgtgtgccgctgctgaaaccgtttatggcagagctgcaa
ccgggcgacctgggtaaagctattccggaaggtgcggtagataacgcgcaactgcgtgat
gtaaatgaagcgattcgcagccatgcgattgagcaggtaggtaagaaactgcgcggctat
atgacggatatgaaacgtattgctgttgcgggttaa

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (8)   
   KEGG PATHWAY (6)   
   KEGG MODULE (2)   
Chemical substance (11)   
   KEGG COMPOUND (11)   
Chemical reaction (7)   
   KEGG ENZYME (1)   
   KEGG REACTION (6)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein domain (8)   
   Pfam (8)   
All databases (40)   

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