KEGG   ENZYME: 1.2.1.31Help
Entry
EC 1.2.1.31                 Enzyme                                 
Name L-aminoadipate-semialdehyde dehydrogenase;
aminoadipate semialdehyde dehydrogenase;
2-aminoadipate semialdehyde dehydrogenase;
alpha-aminoadipate-semialdehyde dehydrogenase;
alpha-aminoadipate reductase;
2-aminoadipic semialdehyde dehydrogenase;
L-alpha-aminoadipate delta-semialdehyde oxidoreductase;
L-alpha-aminoadipate delta-semialdehyde:NAD+ oxidoreductase;
L-alpha-aminoadipate delta-semialdehyde:nicotinamide adenine
dinucleotide oxidoreductase
Class Oxidoreductases;
Acting on the aldehyde or oxo group of donors;
With NAD+ or NADP+ as acceptor
BRITE hierarchy
Sysname L-2-aminoadipate-6-semialdehyde:NAD(P)+ 6-oxidoreductase
Reaction(IUBMB) L-2-aminoadipate 6-semialdehyde + NAD(P)+ + H2O = L-2-aminoadipate +
NAD(P)H + H+ [RN:R03102 R03103]
Reaction(KEGG) R03102 R03103;
(other) R03098 R04390 R04863
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Substrate L-2-aminoadipate 6-semialdehyde [CPD:C04076];
NAD+ [CPD:C00003];
NADP+ [CPD:C00006];
H2O [CPD:C00001]
Product L-2-aminoadipate [CPD:C00956];
NADH [CPD:C00004];
NADPH [CPD:C00005];
H+ [CPD:C00080]
Pathway PATH: ec00300  Lysine biosynthesis
PATH: ec00310  Lysine degradation
PATH: ec01100  Metabolic pathways
Orthology KO: K00142  aminoadipate-semialdehyde dehydrogenase
KO: K00143  aminoadipate-semialdehyde dehydrogenase large subunit
KO: K00144  aminoadipate-semialdehyde dehydrogenase small subunit
Genes HSA: 132949(AASDH) 60496(AASDHPPT)
SCE: YBR115C(LYS2) YGL154C(LYS5)
AGO: AGOS_ADL346W AGOS_AGR382W
KLA: KLLA0B09218g KLLA0E08899g
PIC: PICST_68020(LYS2)
VPO: Kpol_1006p6 Kpol_1043p31
CAL: CaO19.10487(LYS2) CaO19.2970(LYS2)
CGR: CAGL0E05104g CAGL0K07788g
YLI: YALI0E06457g
SPO: SPAP7G5.04c(lys1)
MGR: MGG_02611
ANI: AN5610.2
AFM: AFUA_4G11240
AOR: AO090003001097
ANG: An04g05420
NFI: NFIA_105160
SSL: SS1G_08185
BFU: BC1G_13197
CNE: CNG00170
CNB: CNBG4570
LBC: LACBIDRAFT_184376(LbLYS1)
UMA: UM01697.1
Taxonomy
Structures PDB: 2BYD  2C43  2CG5  
Reference
  Authors
  Title


  Journal
  Organism
 1  [PMID:4285660]
Calvert AF, Rodwell VW.
Metabolism of pipecolic acid in a Pseudomonas species. 3.
L-alpha-aminoadipate delta-semialdehyde:nicotinamide adenine
dinucleotide oxidoreductase.
J. Biol. Chem. 241 (1966) 409-14.
Pseudomonas sp.
Other DBs ExplorEnz - The Enzyme Database: 1.2.1.31
IUBMB Enzyme Nomenclature: 1.2.1.31
ExPASy - ENZYME nomenclature database: 1.2.1.31
BRENDA, the Enzyme Database: 1.2.1.31
CAS: 9067-87-2
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