KEGG   ENZYME: 1.3.1.24Help
Entry
EC 1.3.1.24                 Enzyme                                 

Name
biliverdin reductase
Class
Oxidoreductases;
Acting on the CH-CH group of donors;
With NAD+ or NADP+ as acceptor
BRITE hierarchy
Sysname
bilirubin:NAD(P)+ oxidoreductase
Reaction(IUBMB)
bilirubin + NAD(P)+ = biliverdin + NAD(P)H + H+ [RN:R02391 R02393]
Reaction(KEGG)
Substrate
bilirubin [CPD:C00486];
NAD+ [CPD:C00003];
NADP+ [CPD:C00006]
Product
biliverdin [CPD:C00500];
NADH [CPD:C00004];
NADPH [CPD:C00005];
H+ [CPD:C00080]
History
EC 1.3.1.24 created 1972
Pathway
Porphyrin and chlorophyll metabolism
Orthology
K00214  
biliverdin reductase
K05901  
biliverdin reductase / flavin reductase
Genes
HSA: 
644(BLVRA) 645(BLVRB)
PTR: 
456039(BLVRB) 463366(BLVRA)
PPS: 
100976517(BLVRA) 100989093(BLVRB)
GGO: 
101142015(BLVRB) 101145695(BLVRA)
PON: 
100434664(BLVRA) 100446184(BLVRB)
NLE: 
100581836(BLVRA) 100587172(BLVRB)
MCC: 
700980(BLVRA) 703020(BLVRB)
MCF: 
102136439(BLVRA) 102142962(BLVRB)
CJC: 
100391206(BLVRB) 100404177(BLVRA)
MMU: 
109778(Blvra) 233016(Blvrb)
RNO: 
116599(Blvra) 292737(Blvrb)
CGE: 
100751522(Blvra) 100768929(Blvrb)
HGL: 
101697384(Blvrb) 101722954(Blvra)
TUP: 
102476728(BLVRA) 102490802(BLVRB)
CFA: 
475867(BLVRA) 476456(BLVRB)
AML: 
UMR: 
103661047(BLVRB) 103674578(BLVRA)
FCA: 
101088735(BLVRA) 101092315(BLVRB)
PTG: 
102957548(BLVRA) 102957700(BLVRB)
BTA: 
281650(BLVRB) 504596(BLVRA)
BOM: 
102277747(BLVRB) 102279089(BLVRA)
PHD: 
CHX: 
102186555(BLVRA) 102187796(BLVRB)
OAS: 
101118353(BLVRA) 101119750(BLVRB)
SSC: 
100515289(BLVRA) 100625219(BLVRB)
CFR: 
102503539(BLVRA) 102522968(BLVRB)
BACU: 
103006819(BLVRA) 103014515(BLVRB)
LVE: 
103073162(BLVRA) 103082225(BLVRB)
ECB: 
100064761(BLVRA) 100068145(BLVRB)
MYB: 
MYD: 
PALE: 
MDO: 
SHR: 
OAA: 
GGA: 
396352(P22) 420776(BLVRA)
MGP: 
APLA: 
101793149(BLVRA)
TGU: 
FAB: 
101818701(BLVRA)
PHI: 
FPG: 
FCH: 
102055391(BLVRA)
CLV: 
ASN: 
102371445(BLVRA) 102387963(BLVRB)
AMJ: 
102567480(BLVRA) 102574563(BLVRB)
PSS: 
102463244(BLVRA)
CMY: 
102933712(BLVRA)
ACS: 
100564394(blvra) 100564796(blvrb)
PBI: 
103049956(BLVRA) 103053858(BLVRB)
XLA: 
100137674(blvra) 443881(blvrb)
XTR: 
100124834(blvrb) 448743(blvra)
DRE: 
436959(blvrb) 767661(blvra)
TRU: 
MZE: 
OLA: 
XMA: 
LCM: 
102358034(BLVRB)
CMK: 
103173572(blvrb) 103181265(blvra)
CIN: 
ISC: 
NVE: 
BSUB: 
CTM: 
SYN: 
slr1784(bvdR)
SYZ: 
MYO_12210(bvdR)
SYY: 
SYT: 
SYS: 
SYQ: 
SYP: 
CYA: 
CYB: 
SYNP: 
MAR: 
MAE_61890(bvdR)
CYT: 
cce_1608(bvdR)
CYP: 
CYC: 
CYH: 
CYJ: 
CAN: 
CSN: 
DSL: 
HAO: 
GLP: 
CMP: 
TER: 
LEP: 
GEI: 
OAC: 
ONI: 
PSEU: 
CEP: 
MIC: 
ARP: 
GVI: 
gvip105(bvdR)
GLJ: 
GKIL_1362(bvdR)
ANA: 
alr4149(bvdR)
NPU: 
NOS: 
NOP: 
AVA: 
ANB: 
ACY: 
NAZ: 
CSG: 
CALO: 
CALT: 
RIV: 
CTHE: 
PLP: 
SCS: 
 » show all
Taxonomy
Reference
1  [PMID:4378982]
  Authors
Singleton JW, Laster L.
  Title
Biliverdin reductase of guinea pig liver.
  Journal
J. Biol. Chem. 240 (1965) 4780-9.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
9074-10-6

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