KEGG   ENZYME: 1.3.1.24Help
Entry
EC 1.3.1.24                 Enzyme                                 
Name
biliverdin reductase
Class
Oxidoreductases;
Acting on the CH-CH group of donors;
With NAD+ or NADP+ as acceptor
BRITE hierarchy
Sysname
bilirubin:NAD(P)+ oxidoreductase
Reaction(IUBMB)
bilirubin + NAD(P)+ = biliverdin + NAD(P)H + H+ [RN:R02391 R02393]
Reaction(KEGG)
Substrate
bilirubin [CPD:C00486];
NAD+ [CPD:C00003];
NADP+ [CPD:C00006]
Product
biliverdin [CPD:C00500];
NADH [CPD:C00004];
NADPH [CPD:C00005];
H+ [CPD:C00080]
Pathway
Porphyrin and chlorophyll metabolism
Orthology
K00214  
biliverdin reductase
K05901  
biliverdin reductase / flavin reductase
Genes
HSA: 
644(BLVRA) 645(BLVRB)
PTR: 
456039(BLVRB) 463366(BLVRA)
PPS: 
100976517(BLVRA) 100989093(BLVRB)
GGO: 
101142015(BLVRB) 101145695(BLVRA)
PON: 
100434664(BLVRA) 100446184(BLVRB)
MCC: 
700980(BLVRA) 703020(BLVRB)
MMU: 
109778(Blvra) 233016(Blvrb)
RNO: 
116599(Blvra) 292737(Blvrb)
CFA: 
475867(BLVRA) 476456(BLVRB)
AML: 
FCA: 
101088735(BLVRA) 101092315(BLVRB)
BTA: 
281650(BLVRB) 504596(BLVRA)
SSC: 
100515289 100625219
ECB: 
100064761 100068145
MDO: 
100017892 100029544
SHR: 
100915926 100930351(BLVRB)
OAA: 
100073853 100076047 100681226
GGA: 
396352(P22) 420776(BLVRA)
MGP: 
100542635
TGU: 
100224786(BLVRA)
ACS: 
100564394 100564796
XLA: 
100137674(blvra) 443881(blvrb)
XTR: 
100124834(blvrb) 448743(blvra)
DRE: 
436959(blvrb) 767661(blvra)
TRU: 
101070243
OLA: 
101163919 101175193
CIN: 
100185152
ISC: 
IscW_ISCW003581
NVE: 
NEMVE_v1g220734
BSUB: 
BEST7613_1573(bvdR)
CTM: 
Cabther_A1380
SYN: 
slr1784(bvdR)
SYZ: 
MYO_12210(bvdR)
SYY: 
SYNGTS_0221(bvdR)
SYT: 
SYNGTI_0221(bvdR)
SYS: 
SYNPCCN_0221(bvdR)
SYQ: 
SYNPCCP_0221(bvdR)
SYP: 
SYNPCC7002_A2324(bvdR)
CYA: 
CYA_2461
CYB: 
CYB_1431
SYNP: 
Syn7502_02676
MAR: 
MAE_61890(bvdR)
CYT: 
cce_1608(bvdR)
CYP: 
PCC8801_1204
CYC: 
PCC7424_1770
CYH: 
Cyan8802_1233
CYJ: 
Cyan7822_0090
CAN: 
Cyan10605_2173
CSN: 
Cyast_1886
DSL: 
Dacsa_2266
HAO: 
PCC7418_3675
GLP: 
Glo7428_0283
CMP: 
Cha6605_2462
GVI: 
gvip105(bvdR)
ANA: 
alr4149(bvdR)
NPU: 
Npun_R3726
NOS: 
Nos7107_2542
NOP: 
Nos7524_0955
AVA: 
Ava_0755
ANB: 
ANA_C11517
ACY: 
Anacy_0624
NAZ: 
Aazo_0182
CSG: 
Cylst_4447
CALO: 
Cal7507_5868
CALT: 
Cal6303_0865
RIV: 
Riv7116_4314
TER: 
Tery_0913
LEP: 
Lepto7376_2097
GEI: 
GEI7407_2687
OAC: 
Oscil6304_4400
ONI: 
Osc7112_4818
PSEU: 
Pse7367_2209
CEP: 
Cri9333_0116
MIC: 
Mic7113_3639
ARP: 
NIES39_B00110(bvdR)
CTHE: 
Chro_2639
PLP: 
Ple7327_4594
SCS: 
Sta7437_2854
 » show all
Taxonomy
Reference
1  [PMID:4378982]
  Authors
Singleton JW, Laster L.
  Title
Biliverdin reductase of guinea pig liver.
  Journal
J. Biol. Chem. 240 (1965) 4780-9.
  Organism
Cavia porcellus
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
9074-10-6
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