KEGG   ENZYME: 1.6.6.9Help
Entry
EC 1.6.6.9                  Enzyme                                 

Name
trimethylamine-N-oxide reductase;
trimethylamine N-oxide reductase;
trimethylamine oxide reductase;
TMAO reductase;
TOR
Class
Oxidoreductases;
Acting on NADH or NADPH;
With a nitrogenous group as acceptor
BRITE hierarchy
Sysname
NADH:trimethylamine-N-oxide oxidoreductase
Reaction(IUBMB)
NADH + H+ + trimethylamine N-oxide = NAD+ + trimethylamine + H2O [RN:R02559]
Reaction(KEGG)
R02559;
(other) R02560
Show
Substrate
NADH [CPD:C00004];
H+ [CPD:C00080];
trimethylamine N-oxide [CPD:C01104]
Product
NAD+ [CPD:C00003];
trimethylamine [CPD:C00565];
H2O [CPD:C00001]
History
EC 1.6.6.9 created 1972
Pathway
Methane metabolism
Microbial metabolism in diverse environments
Reference
1  [PMID:4286289]
  Authors
Unemoto T, Hayashi M, Miyaki K, Hayashi M.
  Title
Intracellular localization and properties of trimethylamine-N-oxide reductase in Vibrio parahaemolyticus.
  Journal
Biochim. Biophys. Acta. 110 (1965) 319-28.
  Organism
Vibrio parahaemolyticus
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
UM-BBD (Biocatalysis/Biodegradation Database): 
BRENDA, the Enzyme Database: 
CAS: 
37256-34-1

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