KEGG   ENZYME: 3.4.21.2Help
Entry
EC 3.4.21.2                 Enzyme                                 

Name
chymotrypsin C
Class
Hydrolases;
Acting on peptide bonds (peptidases);
Serine endopeptidases
BRITE hierarchy
Reaction(IUBMB)
Preferential cleavage: Leu!, Tyr!, Phe!, Met!, Trp!, Gln!, Asn!
Comment
Formed from pig chymotrypsinogen C, and from cattle subunit II of procarboxypeptidase A. Reacts more readily with Tos-Leu-CH2Cl than Tos-Phe-CH2Cl in contrast to chymotrypsin. In peptidase family S1 (trypsin family)
History
EC 3.4.21.2 created 1972
Orthology
K01311  
chymotrypsin C
Genes
HSA: 
11330(CTRC)
PTR: 
739685(CTRC)
PPS: 
100993635(CTRC)
GGO: 
101129704(CTRC)
PON: 
100431212(CTRC)
MCC: 
MCF: 
MMU: 
76701(Ctrc)
RNO: 
362653(Ctrc)
CGE: 
HGL: 
101703734(Ctrc)
TUP: 
102495129(CTRC)
CFA: 
478220(CTRC)
AML: 
FCA: 
101081235(CTRC)
PTG: 
102964812(CTRC)
BTA: 
514047(CTRC)
BOM: 
102268940(CTRC)
PHD: 
102325115(CTRC)
CHX: 
102174957(CTRC)
SSC: 
CFR: 
102519329(CTRC)
ECB: 
100054423(CTRC)
MYB: 
102250110(CTRC)
MYD: 
102759310(CTRC)
PALE: 
102878566(CTRC)
MDO: 
100027379(CTRC)
SHR: 
100932004(CTRC)
OAA: 
GGA: 
430670(CTRC)
MGP: 
FAB: 
PHI: 
102104533(CTRC)
APLA: 
101795575(CTRC)
FPG: 
101922683(CTRC)
FCH: 
102051553(CTRC)
CLV: 
102088635(CTRC)
ASN: 
PSS: 
102463762(CTRC)
CMY: 
102940407(CTRC)
XLA: 
443884(ctrc)
XTR: 
493439(ctrc)
TRU: 
 » show all
Taxonomy
Reference
1  [PMID:5792601]
  Authors
Peanasky RJ, Gratecos D, Baratti J, Rovery M.
  Title
Mode of activation of N-terminal sequence of subunit II in bovine procarboxypeptidase A and of porcine chymotrypsinogen C.
  Journal
Biochim. Biophys. Acta. 181 (1969) 82-92.
  Organism
Bos taurus
Reference
2
  Authors
Folk, J.E.
  Title
Chymotrypsin C (porcine pancreas).
  Journal
Methods Enzymol. 19 (1970) 109-112.
Reference
3
  Authors
Wilcox, P.E.
  Title
Chymotrypsinogens - chymotrypsins.
  Journal
Methods Enzymol. 19 (1970) 64-108.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
9036-09-3

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