KEGG   Echinops telfairi (small Madagascar hedgehog): 101642693
Entry
101642693         CDS       T08707                                 
Symbol
PTPN11
Name
(RefSeq) tyrosine-protein phosphatase non-receptor type 11
  KO
K07293  tyrosine-protein phosphatase non-receptor type 11 [EC:3.1.3.48]
Organism
etf  Echinops telfairi (small Madagascar hedgehog)
Pathway
etf04014  Ras signaling pathway
etf04072  Phospholipase D signaling pathway
etf04148  Efferocytosis
etf04360  Axon guidance
etf04625  C-type lectin receptor signaling pathway
etf04630  JAK-STAT signaling pathway
etf04650  Natural killer cell mediated cytotoxicity
etf04660  T cell receptor signaling pathway
etf04670  Leukocyte transendothelial migration
etf04722  Neurotrophin signaling pathway
etf04920  Adipocytokine signaling pathway
etf04931  Insulin resistance
etf05168  Herpes simplex virus 1 infection
etf05205  Proteoglycans in cancer
etf05208  Chemical carcinogenesis - reactive oxygen species
etf05211  Renal cell carcinoma
etf05220  Chronic myeloid leukemia
etf05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:etf00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04014 Ras signaling pathway
    101642693 (PTPN11)
   04630 JAK-STAT signaling pathway
    101642693 (PTPN11)
   04072 Phospholipase D signaling pathway
    101642693 (PTPN11)
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    101642693 (PTPN11)
 09150 Organismal Systems
  09151 Immune system
   04625 C-type lectin receptor signaling pathway
    101642693 (PTPN11)
   04650 Natural killer cell mediated cytotoxicity
    101642693 (PTPN11)
   04660 T cell receptor signaling pathway
    101642693 (PTPN11)
   04670 Leukocyte transendothelial migration
    101642693 (PTPN11)
  09152 Endocrine system
   04920 Adipocytokine signaling pathway
    101642693 (PTPN11)
  09156 Nervous system
   04722 Neurotrophin signaling pathway
    101642693 (PTPN11)
  09158 Development and regeneration
   04360 Axon guidance
    101642693 (PTPN11)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    101642693 (PTPN11)
   05208 Chemical carcinogenesis - reactive oxygen species
    101642693 (PTPN11)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    101642693 (PTPN11)
  09162 Cancer: specific types
   05220 Chronic myeloid leukemia
    101642693 (PTPN11)
   05211 Renal cell carcinoma
    101642693 (PTPN11)
  09172 Infectious disease: viral
   05168 Herpes simplex virus 1 infection
    101642693 (PTPN11)
  09167 Endocrine and metabolic disease
   04931 Insulin resistance
    101642693 (PTPN11)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:etf01009]
    101642693 (PTPN11)
Enzymes [BR:etf01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.48  protein-tyrosine-phosphatase
     101642693 (PTPN11)
Protein phosphatases and associated proteins [BR:etf01009]
 Protein tyrosine phosphatases (PTPs)
  Class I PTPs (Classical)
   Non-receptor PTPs
    101642693 (PTPN11)
SSDB
Motif
Pfam: Y_phosphatase SH2 DSPc PTPlike_phytase Y_phosphatase3
Other DBs
NCBI-GeneID: 101642693
NCBI-ProteinID: XP_004709716
Position
Unknown
AA seq 589 aa
MWFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNTGDYYD
LYGGEKFATLAELVQYYMEHHGQLKEKNGDVIELKYPLNCADPTSERWFHGHLSGKEAEK
LLTEKGKHGSFLVRESQSHPGDCVLSVRTGDDKGESSDGKSKVTHVMIRCQEMKYDVGGG
ERFDSLTDLVEHYKKNPMVETLGTVLQLKQPLNTTRINAAEIESRVRELSKLAETTDKVK
QGFWEEFETLQQQECKLLYSRKEGQRQENKNKNRYKNILPFDHTRVVLHDGDPNEPVSDY
INANIIMPEFQTKCNHAKPKKSYIATQGCLQNTVNDFWRMVFQENSRVIVMTTKEVERGK
SKCVKYWPDEYSLKEYGVMRVRNVKESAAHDYTLRELKLSKVGQGNTERTVWQYHFRTWP
DHGVPSDPGGVLDFLEEVHHKQESIVDAGPVVVHCSAGIGRTGTFIVIDILIDIIREKGV
DCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAVQHYIETLQRRIEEEQKSKRKGHEYTN
IKYSLADQTGGDQSPLLPCTPTPSCTEMREDNARVYENVGLMQQQKSFR
NT seq 1770 nt   +upstreamnt  +downstreamnt
atgtggtttcacccaaatatcaccggtgtggaggcagaaaacctactgctgacaagaggc
gtggatggcagttttttggcgaggcccagtaagagtaaccctggagacttcacactttcc
gttcgaagaaatggagcggtcacccacatcaagatccagaacacgggcgattactatgac
ctgtacggaggggagaagttcgccaccctggctgagctggtgcagtattacatggagcat
cacgggcaactgaaagagaagaacggagatgtgattgagctcaaatatcctctgaactgc
gcagatcctacctcagaaaggtggtttcatgggcacctctctgggaaagaagccgagaag
ttattaacagagaaaggaaaacatgggagctttcttgtgcgtgagagccagagccacccc
ggagattgcgttctgtccgtccgcactggtgatgacaaaggagagagtagtgacggcaag
tccaaagtcacccacgtcatgatccgctgccaggaaatgaagtacgatgtcggtggagga
gagcggtttgactcgctgacggacctcgtggagcattacaagaagaacccgatggtggag
accctgggcaccgtgctgcaactcaagcagcctctcaacacaacccgcatcaatgccgcg
gaaatagagagccgggtgcgagagctaagcaaattagccgagaccacagataaagtcaag
caaggcttttgggaagaatttgagacattgcagcaacaggagtgcaagcttctctacagc
cggaaagagggccagcgacaagagaataaaaacaagaaccgatacaagaacatcctgccc
tttgatcacaccagggtggtcctccacgacggcgatcccaacgagcccgtttccgattac
atcaatgcgaatatcatcatgcctgaatttcaaaccaagtgcaaccacgcaaaacccaag
aagagttacatcgccacccagggctgtctacaaaacacggtgaacgacttctggcggatg
gtgttccaggagaactcccgtgtcatcgtcatgacaacgaaagaagttgagcggggcaag
agcaaatgtgtcaagtactggcccgatgagtactctctcaaagaatacggggtcatgcgt
gttaggaacgtcaaggagagtgccgctcacgactacacgctacgagaacttaaactgtcg
aaggtcggacaagggaacacggagagaacggtctggcaataccactttcggacctggcca
gaccacggcgtgcccagcgaccccggcggcgtgctggacttcctggaggaggtccaccac
aagcaggagagcatcgtggacgcggggcccgtggtggtgcactgcagtgctgggatcggc
cggacggggaccttcatcgtgatcgacatcctcattgacatcatcagagagaaaggcgtt
gactgcgacatcgatgtgcccaaaaccatccagatggtgcgttcccagaggtcagggatg
gtgcagacagaagcacaataccggttcatctacatggccgtccagcattatatcgaaaca
ctacagcgcaggatcgaagaagagcagaaaagcaagaggaaaggacacgaatacacaaat
attaagtattccctagcggaccagaccggaggcgatcagagcccgctcctgccctgtacc
ccaacaccatcctgtaccgaaatgagagaagataacgctagagtctatgaaaacgtgggc
ctgatgcagcagcagaaaagtttcagatga

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (18)   
   KEGG PATHWAY (18)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
Protein sequence (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (5)   
   Pfam (5)   
All databases (33)   

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