KEGG   Felis catus (domestic cat): 101086266
Entry
101086266         CDS       T02385                                 
Symbol
SHMT1
Name
(RefSeq) serine hydroxymethyltransferase, cytosolic
  KO
K00600  glycine hydroxymethyltransferase [EC:2.1.2.1]
Organism
fca  Felis catus (domestic cat)
Pathway
fca00260  Glycine, serine and threonine metabolism
fca00630  Glyoxylate and dicarboxylate metabolism
fca00670  One carbon pool by folate
fca01100  Metabolic pathways
fca01200  Carbon metabolism
fca01230  Biosynthesis of amino acids
fca01240  Biosynthesis of cofactors
fca01523  Antifolate resistance
Module
fca_M00141  C1-unit interconversion, eukaryotes
Brite
KEGG Orthology (KO) [BR:fca00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00630 Glyoxylate and dicarboxylate metabolism
    101086266 (SHMT1)
  09105 Amino acid metabolism
   00260 Glycine, serine and threonine metabolism
    101086266 (SHMT1)
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    101086266 (SHMT1)
 09160 Human Diseases
  09176 Drug resistance: antineoplastic
   01523 Antifolate resistance
    101086266 (SHMT1)
Enzymes [BR:fca01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.2  Hydroxymethyl-, formyl- and related transferases
    2.1.2.1  glycine hydroxymethyltransferase
     101086266 (SHMT1)
SSDB
Motif
Pfam: SHMT DegT_DnrJ_EryC1
Other DBs
NCBI-GeneID: 101086266
NCBI-ProteinID: XP_003996415
EnsemblRapid: ENSFCTG00005013162
UniProt: M3WMK4
Position
E1:11158908..11185413
AA seq 484 aa
MTAQVNGAHKDADLWSSHEKMLAQPLKDCDTEVYDIIKKESNRQRVGLELIASENFASRA
VLEALGSCLNNKYSEGYPGQRYYGGTEFIDELEILCQKRALQVYGLDPQCWGVNVQPYSG
SPANFAVYTALVEPHGRIMGLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGY
INYDQLEENARLFHPKLIIAGTSCYSRNLDYARLRRIADDNGAYLMADMAHISGLVAAGV
VPSPFEHCHVVSTTTHKTLRGCRAGMIFYRRGVRSVDPKTGKETLYNLESLINSAVFPGL
QGGPHNHAIAGVAVALKQAMTPEFRMYQRQVVANCRALAETLMELGYKVVTGGSDNHLIL
VDLRSKGTDGGRAEKVLEACSIACNKNTCPGDKSALRPSGLRLGTPALTSRGFLEKEFQK
VAQFIHRGIELTLQIQDDVGARATLKEFKEKLAGDEKHQRAIRALREEVESFAALFPLPG
LPAF
NT seq 1455 nt   +upstreamnt  +downstreamnt
atgacagctcaagtcaacggggctcacaaggatgctgacctgtggtcctcgcatgagaag
atgctggcacagcccctcaaagactgcgacaccgaggtttacgacatcatcaagaaggag
agtaaccggcagagggttgggctggagctgatcgcctcagagaatttcgccagccgggca
gttctggaggctctgggctcttgcttaaataacaagtactctgaagggtacccagggcag
aggtattatggcgggaccgagttcatcgatgagctggagatcctctgtcagaagcgggcg
ctacaggtctatggtctggacccccaatgctggggggtcaatgtccagccctactcaggc
tccccggcaaacttcgccgtgtataccgcgctggtggaaccccacgggcgcatcatgggc
ctggacctgcccgacgggggccacctgacccacgggttcatgacagacaagaagaaaatc
tctgctacgtccatcttttttgaatctatgccctataaggtgaacccggacactggctac
atcaactatgaccaactggaggaaaatgcccgcctcttccacccgaagctgattattgca
gggaccagctgctactcccgaaacctggattatgctcgactgaggaggatcgcagacgac
aacggggcctatctcatggccgacatggcgcacatcagcgggctggtggctgccggcgtg
gtgccttccccctttgagcactgccacgtggtgtccaccaccacccacaaaaccctgcga
ggctgccgcgccggcatgatcttctacaggagaggagtgcgcagcgtggatcccaagacc
ggcaaagagacactgtacaacctggagtcgctcatcaactctgccgtgttcccgggcctg
cagggaggtccccacaaccacgccattgctggggtcgccgtggccctgaaacaagccatg
actccggaattccggatgtaccagcgccaggtggtggccaactgcagggctctggctgag
accttgatggagctgggctacaaagtggtaacaggtggttctgacaaccatttgatcctc
gtggatctccgttccaaaggcacggatggtggcagggccgagaaggtactagaagcctgc
tctatagcctgcaacaagaacacctgtccaggtgacaaaagcgcactgcggcccagcgga
ctgcgtctggggactccggcactgacgtcccgaggatttttggaaaaagagttccaaaaa
gtggcccagtttattcacagagggatagaactgactctgcagattcaggacgacgttggt
gccagagccaccctgaaggagttcaaggagaaactggccggggacgagaagcaccaaagg
gccatcagggctctcagggaggaagtggagagcttcgcggctctcttccctctgcccggc
ctgcctgccttttag

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (13)   
   KEGG PATHWAY (8)   
   KEGG MODULE (5)   
Chemical substance (7)   
   KEGG COMPOUND (7)   
Chemical reaction (3)   
   KEGG ENZYME (1)   
   KEGG REACTION (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (10)   
   KEGG ORTHOLOGY (1)   
   RefGene (5)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   ENSEMBLRAPID (1)   
   OC (1)   
Protein sequence (2)   
   UniProt (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (2)   
   Pfam (2)   
All databases (41)   

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