KEGG   Francisella salina: F7308_0050
Entry
F7308_0050        CDS       T01560                                 
Name
(GenBank) 2-isopropylmalate synthase
  KO
K01649  2-isopropylmalate synthase [EC:2.3.3.13]
Organism
frt  Francisella salina
Pathway
frt00290  Valine, leucine and isoleucine biosynthesis
frt00620  Pyruvate metabolism
frt01100  Metabolic pathways
frt01110  Biosynthesis of secondary metabolites
frt01210  2-Oxocarboxylic acid metabolism
frt01230  Biosynthesis of amino acids
Module
frt_M00432  Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:frt00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00620 Pyruvate metabolism
    F7308_0050
  09105 Amino acid metabolism
   00290 Valine, leucine and isoleucine biosynthesis
    F7308_0050
Enzymes [BR:frt01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.3  Acyl groups converted into alkyl groups on transfer
    2.3.3.13  2-isopropylmalate synthase
     F7308_0050
SSDB
Motif
Pfam: HMGL-like LeuA_dimer
Other DBs
NCBI-ProteinID: AEI34978
UniProt: F8G7D1
Position
complement(53862..55442)
AA seq 526 aa
MDKKKIYIFDTTLRDGQQSPGAGMSFEDNIAYADLADKLNIDVLEAGFPSASNTDFEIVN
TISKRMAEKNSNMVIAGLCQLRKNQVEITMDALRPSLAIGKARVHMYLPVDPNLAQASLG
SKNDNEQNIKNVYELIKLASDQGFEVEFSAEGYSRLGDTFDYVTDVFRAAVSAGVTVINC
PDTIGGACERENDNYFVKNMTKHAEIIKKEFPDKNIIWSAHCHNDLGLALENSMNAVFDG
PATQVEGCINGVGERAGNASLEQCVMFINLFGEQKDCHYYNDINIANFKTISDFIGKRML
SRQPHHPITGLNSARHTSGGHTNAILKNPLAYQPFHPESVGNEISFIFGPLSGGNHAKKI
IEENGYICDDKEKAAIAQQIKDIYHERRKGITDEELILAYKQIKSPINVSAIDYGKSNGE
TYVELKGKFFGNIDYRITDNGDNSALSALLKGIQEHIPEINISDYFSRSLKDAGINSKSE
TTIIIKTGENSPVVEGIAVDQDIEISSLKALITATNKLYIETNYRK
NT seq 1581 nt   +upstreamnt  +downstreamnt
atggataaaaagaaaatttatatttttgatacaactcttagagatggacaacagtctcct
ggagctgggatgtcttttgaagataatattgcgtatgcagatcttgcagataagctaaat
atcgatgtcctagaagcaggcttcccttcagcaagtaatacagattttgaaatagtaaat
actatctcaaaaagaatggctgagaaaaactctaatatggttattgctggactatgtcag
ttaagaaaaaaccaagtagagatcacaatggatgcattacgtccatcattagcaataggt
aaagctagagttcatatgtatttgcctgtagatccaaatctagctcaagctagtcttggt
agcaaaaatgataacgagcagaatatcaaaaatgtttatgagttaattaagctagctagt
gatcaaggctttgaagtcgagtttagcgcagaaggatattcaagactaggtgatactttt
gactatgttactgatgtttttagggctgcagtatctgctggtgttacagttatcaactgt
cctgacactattggtggagcttgtgagcgtgaaaatgataactactttgtcaaaaatatg
actaaacatgctgaaatcatcaaaaaagaattccctgataaaaatataatctggtcagca
cattgtcataatgatttgggattagcattagagaactctatgaacgctgtatttgatggt
cctgcgacacaagtagagggctgtatcaacggtgttggtgaaagagctggtaacgcatca
ttagaacaatgtgtgatgtttataaacctttttggtgaacaaaaagattgtcattattat
aatgatattaatattgctaattttaaaactatttcagattttattggcaaaagaatgtta
tcaagacaacctcaccaccctatcacaggtctaaactcagcacgacacacttctggtggg
cacaccaatgcgatactaaaaaatcctctagcatatcagccatttcacccagaatctgtc
ggtaatgaaattagctttatttttggtccattatcaggtggtaaccatgctaagaaaatt
atcgaagaaaatggttatatttgtgatgataaagaaaaagcagctatagctcagcaaata
aaagatatttatcatgagcgtagaaaaggtatcacagatgaagaactaatactggcttat
aagcagattaaatctccgattaatgtatcagctatagactacggtaaatctaatggtgaa
acctatgttgagcttaagggaaaattctttggaaatatagactatagaattactgataat
ggcgataactcagctctttcagcactattaaaaggtatacaggagcatataccagagata
aatatttcagattacttctctaggtcattaaaagatgctgggattaactccaaatctgaa
accaccattataatcaaaactggtgaaaatagtccggtcgttgaagggattgctgtagat
caagatattgagatatcttcacttaaagcattaataacagcaactaataagctatatata
gaaacaaactataggaaataa

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (7)   
   KEGG PATHWAY (6)   
   KEGG MODULE (1)   
Chemical substance (5)   
   KEGG COMPOUND (5)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein sequence (1)   
   UniProt (1)   
Protein domain (2)   
   Pfam (2)   
All databases (23)   

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