KEGG   Francisella tularensis subsp. holarctica VT68: CH67_1138
Entry
CH67_1138         CDS       T03714                                 
Name
(GenBank) delta-1-pyrroline-5-carboxylate dehydrogenase
  KO
K13821  RHH-type transcriptional regulator, proline utilization regulon repressor / proline dehydrogenase / delta 1-pyrroline-5-carboxylate dehydrogenase [EC:1.5.5.2 1.2.1.88]
Organism
ftv  Francisella tularensis subsp. holarctica VT68
Pathway
ftv00250  Alanine, aspartate and glutamate metabolism
ftv00330  Arginine and proline metabolism
ftv01100  Metabolic pathways
ftv01110  Biosynthesis of secondary metabolites
Module
ftv_M00970  Proline degradation, proline => glutamate
Brite
KEGG Orthology (KO) [BR:ftv00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00250 Alanine, aspartate and glutamate metabolism
    CH67_1138
   00330 Arginine and proline metabolism
    CH67_1138
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:ftv03000]
    CH67_1138
Enzymes [BR:ftv01000]
 1. Oxidoreductases
  1.2  Acting on the aldehyde or oxo group of donors
   1.2.1  With NAD+ or NADP+ as acceptor
    1.2.1.88  L-glutamate gamma-semialdehyde dehydrogenase
     CH67_1138
  1.5  Acting on the CH-NH group of donors
   1.5.5  With a quinone or similar compound as acceptor
    1.5.5.2  proline dehydrogenase
     CH67_1138
Transcription factors [BR:ftv03000]
 Prokaryotic type
  Ribbon-helix-helix
   Other families
    CH67_1138
SSDB
Motif
Pfam: Aldedh Pro_dh Pro_dh-DNA_bdg PRODH
Other DBs
NCBI-ProteinID: AJI64294
UniProt: A0A0B6DNI3
Position
1016254..1020318
AA seq 1354 aa
MNDLLNHSGEYPISKEIMNIYKYWLIDEKEAMTKLVEKAHMSSVQKAQVRERAYGLVEKV
RKNRLKKSGIDAFMIEYDLSSEEGVVLMCLAEALLRVPDKYTIDLLIKDKLTSAAWKNHV
GMEKHLFVNAATWSLMLTGKILKDPHRSYRKVFQNFLKKTSEPVIRQAMKQAMKIVGKQY
VLGETIEEALKVSEAKVARGYSYSYDMLGEAAMTMDDAEYYYSQYLHAIHELAKYATNTE
IKKNPGISIKLSALHPRYEVAKHQRVHTELYPKLLKLTQLAKDYNVGMNIDAEETERLQI
SLELVERLAHEPSLEGFNGIGIVVQAYQKRAPYVLDYLANLAKKTNRRFMIRLVKGAYWD
AEIKHAQEQGLAGYPVFTRKYHTDVSYQACVKQLFENHQYIYPQFATHNAQTVAVVFELA
NGNRDFEFQCLHGMGDALYDNVVGKEGYEDIPCRIYAPVGGHKHLLAYLVRRLLENGANS
SFVNRIVDENLPIEELIEDPVKKAIDHGCGQHPNIPYPKDIVSPRLNSQGHNTNDFAVLA
DMYKQIEKYTHKNTYKAKPIVSGIDLDKTITESVINPNTNEVIGSVINADAKIAKRALKN
AQSAFEEWSNTPATKRADILEKFADLLEQDTNKFIAIAMIEAGKTLANAIDEVREAVDFC
RYYAAQARKEFNGPIELPALSDHLKQIEFTGRGAMVCISPWNFPLAIFLGQITAVLAAGN
TVVAKPAEQTPIIAYKAVKLLFKAGLPKNVLQFTPGDGATVGSALVKSPVCKGVIFTGST
EVAAIINQTLANKSSEIVPFIAETGGQNAMIVDSSSLPEQVTADVIRSAFDSAGQRCSAL
RILCLQEDIADNYIKMIVGAMKELKIGDSKYIDTDVGPVIDKEAADNLNAYIEEKKSQFK
LIYQAQPNQDTQKGTFVMPTAFEIDKISDLGREQFGPILHILRFKANQLDKLINDINATG
YGLTAGVHSRINEVMNYVKNNLKAGNIYVNRNIVGAVVGVQPFGGQGKSGTGPKAGGPYY
MHRLANEKLSGVGAVEEIYNPEKIAEYEKQTNKLIKDKYTITNIVAGEKAKKDKYTNLKA
ANGKTIGKKYVASVNTVDNAIEIASKEVEIWNHVNAEQRAATIEKFLELLEKERYLIASS
LVVESNISVEDAHIQIDKTIQQVAYYCLQAKKEFAHPQLLPGPTGEIDELSLKGRGVVVS
MCSSSDLLIRFVGQTAAALLAGNTVVAKPAYTGNLTAYNIVKLMLKAGIDSKVLHLVLSD
DEEITSALLFNSKVALVSFSGSVSAVKQVHQALVLRRGAIIPFVAESIAKNGKCTSLAIE
TASPLYLRRFVVEKTVSVDTTASGGNASLMSLEE
NT seq 4065 nt   +upstreamnt  +downstreamnt
atgaatgacttactaaatcactcaggagaatatcctatttctaaagaaataatgaatata
tataaatattggcttatcgatgaaaaagaagccatgacaaagcttgttgaaaaagctcat
atgtcaagcgttcaaaaggcacaagttagagaaagggcttatggcttagtagaaaaagtc
agaaagaatagactcaaaaagtctggcattgatgcgtttatgatcgagtatgacttatca
tcagaagaaggggtagtgctgatgtgtttagctgaagcgctgctaagagtacctgataaa
tatactattgatctgcttatcaaagataagcttacaagtgctgcgtggaaaaaccatgtt
ggtatggaaaagcatctatttgttaatgctgcgacatggagtttgatgttaactggtaaa
attcttaaagatccgcatcgttcttatagaaaagtttttcaaaattttcttaaaaaaact
agtgagccagtaattcgtcaagcaatgaaacaagcaatgaaaattgttggtaagcaatat
gtacttggtgaaactatcgaagaagctctaaaggtatcagaagctaaagtagccagaggc
tatagctattcttatgatatgcttggtgaagctgcaatgacaatggatgatgctgagtac
tattatagtcagtatcttcatgcaatacatgagttagctaagtatgctacaaatacggaa
atcaaaaaaaatccaggaatttctatcaaattatctgctttacatccacgctatgaggtt
gcaaagcaccaaagagttcatacagaattatatccaaaactgcttaagcttacgcaatta
gcaaaagattataatgttgggatgaatatcgatgctgaagaaacagaaagattacaaata
tcattagaactagtagaaagactagctcatgagccatctttagaaggttttaatggtatt
ggtattgttgttcaggcataccaaaaaagagctccttatgtattagattatttagcaaat
cttgctaagaaaactaatagaagatttatgatccgcttagttaagggggcgtattgggat
gccgaaattaagcatgcgcaagagcaaggtttagcaggttatccagtatttacgcgtaaa
tatcacacagacgtctcatatcaggcttgtgttaaacagctttttgagaatcatcaatat
atctatcctcagtttgcaacgcataatgctcagactgtcgctgtagtatttgagttagct
aatggtaatagagattttgaatttcagtgtttacatggtatgggcgatgcgctatatgac
aatgtcgttggtaaagaaggctatgaagatattccatgtagaatatatgcaccagttggt
ggtcataagcatcttttagcatatctagtaagaagactgctagaaaatggtgctaatagc
tcattcgtaaatagaatagtagacgagaatttacctattgaagaattaatagaggatcct
gttaaaaaagctatcgatcatggttgtggtcagcatcctaatattccttatccaaaagat
atagtctcaccaagattaaattcacaaggtcataatactaatgattttgctgttttggct
gatatgtataagcaaatagaaaaatatacgcacaaaaatacatataaagcaaaaccgata
gtttctggtattgatcttgataaaacaattactgaaagtgttataaatccaaatactaat
gaagtcatcggtagcgtaatcaatgctgatgctaaaattgctaaaagagcactaaaaaat
gctcaaagtgcatttgaagagtggagtaatacaccagcaacaaaaagagcagatattcta
gagaaatttgctgatcttttagaacaagatactaataaatttattgctatagcaatgatt
gaagctggtaaaaccttggctaatgctatagatgaggttagagaggctgtagatttttgt
cgttattatgctgcacaagctagaaaagaatttaatggtcctattgaattgccagcttta
tcagatcatcttaagcagatagagtttaccggtcgcggagctatggtatgtattagccct
tggaatttcccattggcaatattcttaggacagataacagctgttttagcagctggtaat
acagtagttgctaaaccagcagagcagacgccaataatagcttataaggctgttaagctt
ttatttaaagctggtttacctaaaaatgttttacaatttacgcctggtgatggtgcaaca
gttggtagtgctctggttaagagcccagtatgtaaaggtgtgattttcacaggctctaca
gaggttgcagctattataaatcagactttggcaaacaaatctagtgaaatagtaccattt
attgctgagacaggtggacaaaacgctatgattgttgactcatcatcgcttcctgagcag
gttaccgcagatgtgatacgttcagcttttgatagcgcgggacaacgctgttcagcatta
cgtatcttatgtcttcaagaagatatcgctgataactatattaagatgatagttggtgca
atgaaagaacttaaaataggcgattctaaatatattgatactgatgttggtcctgtgatc
gataaagaggctgctgataatctaaatgcgtatattgaagagaaaaaaagccagtttaag
cttatatatcaagctcaacctaaccaagatacacaaaagggcacatttgtgatgcctact
gcttttgagatagataaaatatctgatttgggtagagagcagtttggtccaattttacat
atcttgcgttttaaggctaatcaactagataagcttatcaacgacatcaatgctacagga
tatggtctaacagccggtgtgcatagtcgaattaatgaagtgatgaactatgttaaaaat
aaccttaaagctggtaatatctatgtaaataggaatattgttggtgctgttgttggtgtc
caaccatttggtggtcaaggcaaatctggaacaggtcctaaagctggcggcccttattat
atgcatcgtttagctaatgaaaaattatcaggagtaggtgccgttgaagagatctacaat
cctgaaaaaatagctgaatatgaaaagcagactaacaagcttatcaaagataaatatact
atcacaaatattgttgctggtgagaaagctaaaaaagataaatatactaatcttaaagca
gcaaatggtaaaacgattggtaagaaatatgtagcttctgtgaatactgtagataatgct
atagaaattgctagtaaagaggtagagatatggaatcatgttaatgctgaacaaagagct
gccactattgagaaattcttagaactattagagaaagagcgttatttgatagcttcatct
cttgtagtggagtcaaatatttcagttgaggatgctcatatccaaatagataaaactatt
cagcaggtggcatactattgcctacaagctaaaaaagagtttgctcatccacaactttta
cctggacctacaggagagattgatgagttaagcttaaaaggtcgaggtgttgtagtaagt
atgtgttcaagttctgatttactgatcagatttgttggtcaaactgctgcggctttacta
gcgggtaatactgtagtagctaagccagcatataccggtaatttaactgcttataatatt
gttaaattaatgttaaaagcgggaatagactctaaagtacttcatctagtgttgtcagat
gatgaagagataacatcagctttattatttaatagtaaggttgcactagtttccttctct
ggtagtgtttctgcggttaaacaggttcatcaggctttagtattacgtagaggtgcgatt
ataccttttgttgctgagagtattgctaaaaatggcaaatgtacaagcttagcaatagaa
acagcttcaccattgtatttacgcaggtttgtagttgaaaaaaccgtaagtgttgataca
actgcctctggtggtaatgcttctttaatgagcctagaagaataa

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (5)   
   KEGG PATHWAY (4)   
   KEGG MODULE (1)   
Chemical substance (15)   
   KEGG COMPOUND (15)   
Chemical reaction (10)   
   KEGG ENZYME (2)   
   KEGG REACTION (8)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein sequence (1)   
   UniProt (1)   
Protein domain (4)   
   Pfam (4)   
All databases (42)   

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