KEGG   Gorilla gorilla gorilla (western lowland gorilla): 101125384
Entry
101125384         CDS       T02442                                 
Symbol
IKBKE
Name
(RefSeq) inhibitor of nuclear factor kappa-B kinase subunit epsilon
  KO
K07211  inhibitor of nuclear factor kappa-B kinase subunit epsilon [EC:2.7.11.10]
Organism
ggo  Gorilla gorilla gorilla (western lowland gorilla)
Pathway
ggo04620  Toll-like receptor signaling pathway
ggo04621  NOD-like receptor signaling pathway
ggo04622  RIG-I-like receptor signaling pathway
ggo04623  Cytosolic DNA-sensing pathway
ggo04625  C-type lectin receptor signaling pathway
ggo04657  IL-17 signaling pathway
ggo04936  Alcoholic liver disease
ggo05160  Hepatitis C
ggo05161  Hepatitis B
ggo05162  Measles
ggo05164  Influenza A
ggo05165  Human papillomavirus infection
ggo05167  Kaposi sarcoma-associated herpesvirus infection
ggo05168  Herpes simplex virus 1 infection
ggo05169  Epstein-Barr virus infection
ggo05171  Coronavirus disease - COVID-19
ggo05207  Chemical carcinogenesis - receptor activation
ggo05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:ggo00001]
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    101125384 (IKBKE)
   04621 NOD-like receptor signaling pathway
    101125384 (IKBKE)
   04622 RIG-I-like receptor signaling pathway
    101125384 (IKBKE)
   04623 Cytosolic DNA-sensing pathway
    101125384 (IKBKE)
   04625 C-type lectin receptor signaling pathway
    101125384 (IKBKE)
   04657 IL-17 signaling pathway
    101125384 (IKBKE)
 09160 Human Diseases
  09161 Cancer: overview
   05207 Chemical carcinogenesis - receptor activation
    101125384 (IKBKE)
  09172 Infectious disease: viral
   05161 Hepatitis B
    101125384 (IKBKE)
   05160 Hepatitis C
    101125384 (IKBKE)
   05171 Coronavirus disease - COVID-19
    101125384 (IKBKE)
   05164 Influenza A
    101125384 (IKBKE)
   05162 Measles
    101125384 (IKBKE)
   05168 Herpes simplex virus 1 infection
    101125384 (IKBKE)
   05167 Kaposi sarcoma-associated herpesvirus infection
    101125384 (IKBKE)
   05169 Epstein-Barr virus infection
    101125384 (IKBKE)
   05165 Human papillomavirus infection
    101125384 (IKBKE)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    101125384 (IKBKE)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    101125384 (IKBKE)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:ggo01001]
    101125384 (IKBKE)
Enzymes [BR:ggo01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.10  IkappaB kinase
     101125384 (IKBKE)
Protein kinases [BR:ggo01001]
 Serine/threonine kinases: Other
  IKK family [OT]
   101125384 (IKBKE)
SSDB
Motif
Pfam: TBK1_CCD1 Pkinase TBK1_ULD PK_Tyr_Ser-Thr ABC1 Pkinase_fungal Kinase-like RH_dom DUF5798
Other DBs
NCBI-GeneID: 101125384
NCBI-ProteinID: XP_018885285
Ensembl: ENSGGOG00000015253
UniProt: G3RVG0
Position
1:177179659..177205731
AA seq 716 aa
MQSTANYLWHTDDLLGQGATASVYKARNKKSGELVAVKVFNTTSYLRPREVQVREFEVLR
KLNHQNIVKLFAVEETGGSRQKVLVMEYCSSGSLLSVLESPENAFGLPEDEFLVVLRCVV
AGMNHLRENGIVHRDIKPGNIMRLVGEEGQSIYKLTDFGAARELDDDEKFVSVYGTEEYL
HPDMYERAVLRKPQQKAFGVTVDLWSIGVTLYHAATGSLPFIPFGGPRRNKEIMYRITTE
KPAGAIAGAQRRENGPLEWSYTLPITCQLSLGLQSQLVPILANILEVEQAKCWGFDQFFA
ETSDILQRVVVHVFSLSQAVLHHIYIHAHNTIAIFQEAVHKQTSVAPRHQEYLFEGHLCV
LEPSVSAQHIAHTTASSPLTLFSTAIPKGLAFRDPALDVPKFVPKVDLQADYNTAKGVLG
AGYQALRLARALLDGQELMFRGLHWVMEVLQATCRRTLEVARTSLLYLSSSLGTERFSSV
TGTPEIQELKAAAELRSRLRTLAEVLSRCSQNITETQESLSSLNRELVKSRDQVHEDRSI
QQIQCCLDKMNFIYKQFKKSRMRPGLGYNEEQIHKLDKVNFSHLAKRLLQVFQEECVQKY
QASLVTHGKRMRVVHETRNHLRLVGCSVAACNTEAQGVQESLSKLLEELSHQLLQDRAKG
AQASPPPIAPYPSPPRKDLLLHMQELCEGMKLLASDLLDNNRIIERLNRVPAPPDV
NT seq 2151 nt   +upstreamnt  +downstreamnt
atgcagagcacagccaattacctgtggcacacagacgacctgctggggcagggggccact
gccagtgtgtacaaggcccgcaacaagaaatccggagagctggttgctgtgaaggtcttc
aacactaccagctacctgcggccccgcgaggtgcaggtgagggagttcgaggtcctgcgg
aagctgaaccaccagaacatcgtcaagctctttgcggtggaggagacgggcggaagccgg
cagaaggtactggtgatggagtactgctccagtgggagcctgctgagtgtgctggagagc
cctgagaatgcctttgggctgcctgaggatgagttcctggtggtgctgcgctgtgtggtg
gccggcatgaaccacctgcgggagaacggcattgtgcatcgtgacatcaagcccgggaac
atcatgcgcctcgtaggggaggaggggcagagcatctacaagctgacagacttcggggct
gcccgggagctggatgatgatgagaagttcgtctcggtctatgggactgaggagtacctg
catcccgacatgtatgagcgggcggtgcttcgaaagccccagcaaaaagcgttcggggtg
actgtggatctctggagcattggagtgaccttgtaccacgcagccaccggcagcctgccc
ttcatcccctttggtgggccacggcggaacaaggagatcatgtaccggatcaccacggag
aagccggctggggccattgcaggtgcccagaggcgggagaacgggcccctggagtggagc
tacaccctccccatcacctgccagctgtcactggggctgcagagccagctggtgcccatc
ctggccaacatcctggaggtggagcaggccaagtgctggggcttcgaccagttctttgcg
gagaccagtgacatcctgcagcgagttgtcgtccatgtcttctccctgtcccaggcagtc
ctgcaccacatctatatccatgcccacaacacgatagccattttccaggaggccgtgcac
aagcagaccagtgtggccccccggcaccaggagtacctctttgagggtcacctctgtgtc
ctcgagcccagcgtctcagcacagcacatcgcccacacgacggcaagcagccccctgacc
ctcttcagcacagccatccccaaggggctggccttcagggaccctgctctggacgtcccc
aagttcgtccccaaagtggacctgcaggcggattacaacactgccaagggtgtgttgggc
gccggctaccaggccctgcggctggcacgggccctgctggatgggcaggagctaatgttt
cgggggctgcactgggtcatggaggtgctccaggccacatgcagacggactctggaagtg
gcaaggacatccctcctctacctcagcagcagcctgggaactgagaggttcagcagcgtg
actggaacgcctgagatccaggaactgaaggcggccgcagaactgaggtccaggctgcgg
actctagctgaggtcctctccagatgctcccaaaatatcacggagacccaggagagcctg
agcagcctgaaccgggagctggtgaagagccgggatcaggtacatgaggacagaagcatc
cagcagattcagtgctgtttggacaagatgaacttcatctacaaacagttcaagaagtct
aggatgaggccagggcttggctacaacgaggagcagattcacaagctggataaggtgaat
ttcagtcatttagccaaaagactcctgcaggtgttccaggaggagtgcgtgcagaagtat
caagcgtccttagtcacacatggcaagaggatgagggtggtacacgagaccaggaaccac
ctgcgcctggtcggctgttctgtggctgcctgtaacacagaagcccagggggtccaggag
agtctcagcaagctcctggaagagctatctcaccagctccttcaggaccgagcaaagggg
gctcaggcctcgccgcctcccatagctccttaccccagccctccacgaaaggacctgctt
ctccacatgcaagagctctgcgaggggatgaagctgctggcatctgacctcctggataac
aaccgcatcatcgaacggctaaatagagtcccagcacctcctgatgtctga

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (18)   
   KEGG PATHWAY (18)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (5)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (6)   
   UniProt (1)   
   RefSeq(pep) (5)   
DNA sequence (5)   
   RefSeq(nuc) (5)   
Protein domain (9)   
   Pfam (9)   
All databases (48)   

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