KEGG   Gorilla gorilla gorilla (western lowland gorilla): 101125504
Entry
101125504         CDS       T02442                                 
Symbol
TGFB2
Name
(RefSeq) transforming growth factor beta-2 proprotein isoform X2
  KO
K13376  transforming growth factor beta-2
Organism
ggo  Gorilla gorilla gorilla (western lowland gorilla)
Pathway
ggo04010  MAPK signaling pathway
ggo04060  Cytokine-cytokine receptor interaction
ggo04068  FoxO signaling pathway
ggo04110  Cell cycle
ggo04218  Cellular senescence
ggo04350  TGF-beta signaling pathway
ggo04380  Osteoclast differentiation
ggo04390  Hippo signaling pathway
ggo04933  AGE-RAGE signaling pathway in diabetic complications
ggo05140  Leishmaniasis
ggo05142  Chagas disease
ggo05144  Malaria
ggo05145  Toxoplasmosis
ggo05146  Amoebiasis
ggo05152  Tuberculosis
ggo05161  Hepatitis B
ggo05166  Human T-cell leukemia virus 1 infection
ggo05200  Pathways in cancer
ggo05205  Proteoglycans in cancer
ggo05206  MicroRNAs in cancer
ggo05210  Colorectal cancer
ggo05211  Renal cell carcinoma
ggo05212  Pancreatic cancer
ggo05220  Chronic myeloid leukemia
ggo05225  Hepatocellular carcinoma
ggo05226  Gastric cancer
ggo05321  Inflammatory bowel disease
ggo05323  Rheumatoid arthritis
ggo05410  Hypertrophic cardiomyopathy
ggo05414  Dilated cardiomyopathy
ggo05415  Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:ggo00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    101125504 (TGFB2)
   04350 TGF-beta signaling pathway
    101125504 (TGFB2)
   04390 Hippo signaling pathway
    101125504 (TGFB2)
   04068 FoxO signaling pathway
    101125504 (TGFB2)
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    101125504 (TGFB2)
 09140 Cellular Processes
  09143 Cell growth and death
   04110 Cell cycle
    101125504 (TGFB2)
   04218 Cellular senescence
    101125504 (TGFB2)
 09150 Organismal Systems
  09158 Development and regeneration
   04380 Osteoclast differentiation
    101125504 (TGFB2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    101125504 (TGFB2)
   05206 MicroRNAs in cancer
    101125504 (TGFB2)
   05205 Proteoglycans in cancer
    101125504 (TGFB2)
  09162 Cancer: specific types
   05210 Colorectal cancer
    101125504 (TGFB2)
   05212 Pancreatic cancer
    101125504 (TGFB2)
   05225 Hepatocellular carcinoma
    101125504 (TGFB2)
   05226 Gastric cancer
    101125504 (TGFB2)
   05220 Chronic myeloid leukemia
    101125504 (TGFB2)
   05211 Renal cell carcinoma
    101125504 (TGFB2)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    101125504 (TGFB2)
   05161 Hepatitis B
    101125504 (TGFB2)
  09171 Infectious disease: bacterial
   05152 Tuberculosis
    101125504 (TGFB2)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    101125504 (TGFB2)
   05144 Malaria
    101125504 (TGFB2)
   05145 Toxoplasmosis
    101125504 (TGFB2)
   05140 Leishmaniasis
    101125504 (TGFB2)
   05142 Chagas disease
    101125504 (TGFB2)
  09163 Immune disease
   05323 Rheumatoid arthritis
    101125504 (TGFB2)
   05321 Inflammatory bowel disease
    101125504 (TGFB2)
  09166 Cardiovascular disease
   05410 Hypertrophic cardiomyopathy
    101125504 (TGFB2)
   05414 Dilated cardiomyopathy
    101125504 (TGFB2)
   05415 Diabetic cardiomyopathy
    101125504 (TGFB2)
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    101125504 (TGFB2)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and neuropeptides [BR:ggo04052]
    101125504 (TGFB2)
   00536 Glycosaminoglycan binding proteins [BR:ggo00536]
    101125504 (TGFB2)
Cytokines and neuropeptides [BR:ggo04052]
 Cytokines
  Transforming growth factors (RSTK binding)
   101125504 (TGFB2)
Glycosaminoglycan binding proteins [BR:ggo00536]
 Heparan sulfate / Heparin
  Growth factors/receptors
   101125504 (TGFB2)
SSDB
Motif
Pfam: TGFb_propeptide TGF_beta SPEG_u2
Other DBs
NCBI-GeneID: 101125504
NCBI-ProteinID: XP_004028463
Ensembl: ENSGGOG00000004593
UniProt: A0A2I2ZKR7
Position
1:196952865..197051482
AA seq 414 aa
MHYCVLSAFLILHLVTVALSLSTCSTLDMDQFMRKRIEAIRGQILSKLKLTSPPEDYPEP
EEVPPEVISIYNSTRDLLQEKASRRAAACERERSDEEYYAKEVYKIDMPPFFPSENAIPP
TFYRPYFRIVRFDVSAMEKNASNLVKAEFRVFRLQNPKARVPEQRIELYQILKSKDLTSP
TQRYIDSKVVKTRAEGEWLSFDVTDAVHEWLHHKDRNLGFKISLHCPCCTFVPSNNYIIP
NKSEELEARFAGIDGTSTYTSGDQKTIKSTRKKNSGKTPHLLLMLLPSYRLESQQTNRRK
KRALDAAYCFRNVQDNCCLRPLYIDFKRDLGWKWIHEPKGYNANFCAGACPYLWSSDTQH
SRVLSLYNTINPEASASPCCVSQDLEPLTILYYIGKTPKIEQLSNMIVKSCKCS
NT seq 1245 nt   +upstreamnt  +downstreamnt
atgcactactgtgtgctgagcgcttttctgatcctgcatctggtcacggtcgcgctcagc
ctgtctacctgcagcacactcgatatggaccagttcatgcgcaagaggatcgaggcgatc
cgcgggcagatcctgagcaagctgaagctcaccagtcccccagaagactatcctgagccc
gaggaagtccccccggaggtgatttccatctacaacagcaccagggacttgctccaggag
aaggcgagccggagggcggccgcctgcgagcgcgagaggagcgacgaagagtactacgcc
aaggaggtttacaaaatagacatgccgcccttcttcccctccgaaaatgccatcccgccc
actttctacagaccctacttcagaattgttcgattcgacgtctcagcaatggagaagaat
gcttccaatttggtgaaagcagagttcagagtctttcgtttgcagaacccaaaagccaga
gtgcctgaacaacggattgagctgtatcagattctcaagtccaaagatttaacatctcca
acccagcgctacatcgacagcaaagttgtgaaaacaagagcagaaggcgaatggctctcc
ttcgatgtaactgatgctgttcatgaatggcttcaccataaagacaggaacctgggattt
aaaataagcttacactgtccctgctgcacttttgtaccatctaataattacatcatccca
aataaaagtgaagaactagaagcaagatttgcaggtattgatggcacctccacatatacc
agtggtgatcagaaaactataaagtccactaggaaaaaaaacagtgggaagaccccacat
ctcctgctaatgttattgccctcctacagacttgagtcacaacagaccaaccggcggaag
aagcgtgctttggatgcggcctattgctttagaaatgtgcaggataattgctgcctacgt
ccactttacattgatttcaagagggatctagggtggaaatggatacacgaacccaaaggg
tacaatgccaacttctgtgctggagcatgcccatatttatggagttcagacactcagcac
agcagggtcctgagcttatataataccataaatccagaagcatctgcttctccttgctgc
gtgtcccaagatttagaacctctaaccattctctactacattggcaaaacacccaagatt
gaacagctttctaatatgattgtaaagtcttgcaaatgcagctaa

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