KEGG   Gekko japonicus (Schlegel's Japanese gecko): 107119326
Entry
107119326         CDS       T04299                                 
Symbol
MTHFD1
Name
(RefSeq) methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1
  KO
K00288  methylenetetrahydrofolate dehydrogenase (NADP+) / methenyltetrahydrofolate cyclohydrolase / formyltetrahydrofolate synthetase [EC:1.5.1.5 3.5.4.9 6.3.4.3]
Organism
gja  Gekko japonicus (Schlegel's Japanese gecko)
Pathway
gja00670  One carbon pool by folate
gja01100  Metabolic pathways
gja01240  Biosynthesis of cofactors
Module
gja_M00141  C1-unit interconversion, eukaryotes
Brite
KEGG Orthology (KO) [BR:gja00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    107119326 (MTHFD1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:gja04147]
    107119326 (MTHFD1)
Enzymes [BR:gja01000]
 1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.5  methylenetetrahydrofolate dehydrogenase (NADP+)
     107119326 (MTHFD1)
 3. Hydrolases
  3.5  Acting on carbon-nitrogen bonds, other than peptide bonds
   3.5.4  In cyclic amidines
    3.5.4.9  methenyltetrahydrofolate cyclohydrolase
     107119326 (MTHFD1)
 6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.4  Other carbon-nitrogen ligases
    6.3.4.3  formate---tetrahydrofolate ligase
     107119326 (MTHFD1)
Exosome [BR:gja04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   107119326 (MTHFD1)
SSDB
Motif
Pfam: FTHFS THF_DHG_CYH_C THF_DHG_CYH OCD_Mu_crystall
Other DBs
NCBI-GeneID: 107119326
NCBI-ProteinID: XP_015277280
Position
Un
AA seq 766 aa
ICDVNLLFLSLLLCPRPLSRQVRERLKNQVANLKETAPGFRPGLAILQVGDRDDSNLYIS
MKLKAAAEIGINANHIKLPNSASEAEVLRCIHALNEDPAIHGFIVQLPLDSNKPINTEKI
TNAVAPEKDVDGLSSINAGKLSRGDLGDCFIPCTPKGCMELIRQTGIQVAGKRAVVIGRS
KIVGAPMHDLLLWNHATVTTCHSKTASLAEEVSKADILVVAAGKAEMVKGEWIKPGAVVI
DCGINHIPDSTKASGKRVVGDVAYAAAKERASYITPVPGGVGPMTVAMLMQSTVESAQRF
VEKYRPGKWNIQYNQLIPKIPVPSDIEVSRSCVPKPVGQLAREIGLLSDEVELYGQNKAK
ILLSTLERLKAQPDGKYVVVTGITPTPLGEGKSTTTIGLVQALGVHLGRNAFACVRQPSQ
GPTFGIKGGAAGGGYSQVVPMEEFNLHLTGDIHAITAANNLVAAAIDARIFHEATQSDQA
LYSRLVPSVDGARKFSDIQIRRLQRLRINKTDPDTLTAGEIKKFVRLDIDPESITWARVL
DTSDRFLRKITIGQSPTEKGHSRTTQFDITVASEIMAVLALTDSLEDMRRRLARMVVASS
REGIPVTTEDLGVSGALTVLMKDAIKPNLMQSLEGDPVFVHAGPFANIAHGNSSVLADKI
ALKLVGKEGFVVTEAGFGADIGMEKFFDIKCRYSGLQPHVAVLVATVRALKMHGGGPTVT
AGVPLPKEYTEENLQLLAKGCCNLSKQIQNARTFGVPVVVAVNAFK
NT seq 2302 nt   +upstreamnt  +downstreamnt
gatttgtgatgtgaatttgctctttctgtctcttctcctgtgcccccgccccctttctag
gcaagtacgggagagactgaagaaccaagtggcgaacctgaaggagacagccccgggatt
caggccaggacttgcgattttgcaggttggcgatcgggatgattcaaatctctacattag
catgaagctgaaggcggcggctgagatcgggatcaacgccaatcacatcaagctgccaaa
tagtgcatcagaagcggaggtgctgaggtgcattcatgcactgaacgaagatccggccat
tcatggatttatcgtgcagctgcctctggattcgaacaagcccatcaacactgagaaaat
aaccaacgctgtggcacccgagaaggacgtggatggcttgagcagcatcaacgcagggaa
gctttcgcgaggtgacctcggagactgtttcatcccctgcacacccaaagggtgtatgga
actcatcaggcaaacgggtatccaagtggcgggcaagagagccgtggtgattgggcggag
taagatagtcggcgcgccgatgcatgacctgctgctctggaaccatgccaccgtgaccac
gtgtcactccaagacggcatcactggctgaggaagtcagcaaagcggatatcttggtagt
tgcagctggcaaagccgagatggtgaaaggggagtggattaagcctggcgcggtcgtgat
agattgcgggatcaaccacataccagatagcacaaaggccagtgggaaaagggtagttgg
tgatgtggcttacgctgcagccaaggagagggcctcttacatcaccccagtgcctggtgg
ggtcggaccaatgactgtggccatgctgatgcagagcaccgtagaaagcgcccagcgttt
cgtagagaaataccggcctggcaagtggaatattcagtacaaccagctcattcccaaaat
ccccgtcccaagtgacatcgaagtctctcggtcgtgcgttcccaagcccgttggccagct
ggccagagagatcggcttgctctccgacgaggtggagctctacggtcagaacaaggccaa
gattttgctttcgaccctggaacgcctgaaagcccagccagatggcaaatacgttgtcgt
cacagggataacccccacgcctctgggcgaagggaagagcaccacgacgatcgggctggt
ccaggccctgggagtgcacctgggtcggaatgccttcgcctgtgtccggcagccatcaca
gggacccactttcgggatcaaagggggtgctgccggagggggctattctcaggttgttcc
tatggaggagttcaatctccatctcactggtgacattcatgccattacggcagccaataa
cctggtggctgccgccatcgatgcccgcatttttcatgaagcgacacaatccgatcaggc
tctttactctcgcttggttccttcagtcgacggcgccaggaagttttccgatatccagat
ccggagactgcagagattacgtattaacaaaacggacccagacactttgacggcaggcga
aataaagaaatttgtgagactggatattgatccagagagcataacgtgggcaagagtgtt
ggacaccagtgaccggtttctgcggaagatcactatcggccagtctccgacagagaaagg
gcatagccgcacaacgcagtttgacatcacggtagccagtgagatcatggctgttttagc
gctcacggacagcctggaagatatgaggagacgcctggcccgaatggtggtcgcttccag
tagggaaggtatcccagttaccacagaagatctgggagtgagtggtgctctaacggttct
gatgaaagacgctattaagccaaatctcatgcagagtttggagggcgacccggtgttcgt
ccacgctgggccgtttgccaacatcgctcatggcaactcttccgtcctggcagacaagat
cgccctcaagctggttggcaaggaagggtttgtggtgacagaagctggcttcggagcgga
tataggcatggagaagttcttcgacatcaagtgtcggtactctggcctccagccccacgt
ggccgtcttggttgccaccgtccgagctctaaagatgcacggtggagggcccacggtcac
agccggggtccccttgccaaaggaatacacagaagagaaccttcagcttctggcaaaggg
ctgttgtaacttgagcaagcagatccagaatgcccggacctttggcgtcccagtcgtggt
ggcggtcaacgccttcaagtaa

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (4)   
   KEGG PATHWAY (3)   
   KEGG MODULE (1)   
Chemical substance (12)   
   KEGG COMPOUND (12)   
Chemical reaction (6)   
   KEGG ENZYME (3)   
   KEGG REACTION (3)   
Genome (1)   
   KEGG GENOME (1)   
Gene (5)   
   KEGG ORTHOLOGY (1)   
   RefGene (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (4)   
   Pfam (4)   
All databases (37)   

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