KEGG   Hipposideros armiger (great roundleaf bat): 109372224
Entry
109372224         CDS       T04661                                 
Symbol
SLC8A2
Name
(RefSeq) sodium/calcium exchanger 2 isoform X1
  KO
K05849  solute carrier family 8 (sodium/calcium exchanger)
Organism
hai  Hipposideros armiger (great roundleaf bat)
Pathway
hai04020  Calcium signaling pathway
hai04022  cGMP-PKG signaling pathway
hai04260  Cardiac muscle contraction
hai04261  Adrenergic signaling in cardiomyocytes
hai04371  Apelin signaling pathway
hai04740  Olfactory transduction
hai04961  Endocrine and other factor-regulated calcium reabsorption
hai04974  Protein digestion and absorption
hai04978  Mineral absorption
hai05410  Hypertrophic cardiomyopathy
hai05412  Arrhythmogenic right ventricular cardiomyopathy
hai05414  Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:hai00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04371 Apelin signaling pathway
    109372224 (SLC8A2)
   04020 Calcium signaling pathway
    109372224 (SLC8A2)
   04022 cGMP-PKG signaling pathway
    109372224 (SLC8A2)
 09150 Organismal Systems
  09153 Circulatory system
   04260 Cardiac muscle contraction
    109372224 (SLC8A2)
   04261 Adrenergic signaling in cardiomyocytes
    109372224 (SLC8A2)
  09154 Digestive system
   04974 Protein digestion and absorption
    109372224 (SLC8A2)
   04978 Mineral absorption
    109372224 (SLC8A2)
  09155 Excretory system
   04961 Endocrine and other factor-regulated calcium reabsorption
    109372224 (SLC8A2)
  09157 Sensory system
   04740 Olfactory transduction
    109372224 (SLC8A2)
 09160 Human Diseases
  09166 Cardiovascular disease
   05410 Hypertrophic cardiomyopathy
    109372224 (SLC8A2)
   05412 Arrhythmogenic right ventricular cardiomyopathy
    109372224 (SLC8A2)
   05414 Dilated cardiomyopathy
    109372224 (SLC8A2)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters [BR:hai02000]
    109372224 (SLC8A2)
   00536 Glycosaminoglycan binding proteins [BR:hai00536]
    109372224 (SLC8A2)
Transporters [BR:hai02000]
 Solute carrier family (SLC)
  SLC8: Na+/Ca2+ exchanger
   109372224 (SLC8A2)
Glycosaminoglycan binding proteins [BR:hai00536]
 Heparan sulfate / Heparin
  Others
   109372224 (SLC8A2)
SSDB
Motif
Pfam: Calx-beta Na_Ca_ex_C Na_Ca_ex
Other DBs
NCBI-GeneID: 109372224
NCBI-ProteinID: XP_019480767
EnsemblRapid: ENSHARG00000019700
UniProt: A0A8B7PYJ8
Position
Unknown
AA seq 942 aa
MAPLALVGFALLLGAPPCSGAATPTPSLPPPPANDSDASTEACQGSNRCQPGVLLPVWEP
DDPSLGDKAARAVVYFVAMVYMFLGVSIIADRFMASIEVITSKEKEITITKANGETSVGT
VRIWNETVSNLTLMALGSSAPEILLSVIEVCGHNFQAGELGPGTIVGSAAFNMFVVIAVC
VYVIPAGESRKIKHLRVFFVTASWSIFAYVWLYLILAVFSPGVVQVWEALLTLVFFPVCV
VFAWMADKRLLFYKYVYKRYRTDPRSGIIIGAEGDPPKSIELDGTFVGAEAPGEVGGLGP
GPAEARELDASRREVIQILKDLKQKHPDKDLEQLVGIANYYALLHQQKSRAFYRIQATRL
MTGAGNVLRRHAVDASRRASPADGPGEDEDDGASHIFFEPSLYHCLENCGSVLLSVTCQG
GEGNSTFYVDYRTEDGSAKAGSDYEYSEGTLVFKPGETQKELRIGIIDDDIFEEDEHFFV
RLLNLRVGDAQGMFEPDGGGRPKGRLVAPLLATVTILDDDHAGIFSFQDRLLHVSECMGT
VDVRVVRSSGARGTVRLPYRTVDGTARGGGVHYEDACGELEFGDDETMKTLQVKIVDDEE
YEKKDNFFIELGQPQWLKRGISDHGPELHREAISLSVCLSPALLLNQGDGDRKLTAEEEE
ARRIAEMGKPVLGENCRLEVIIEESYDFKNTVDKLIKKTNLALVIGTHSWREQFLEAITV
SAGAVRLRAPHRVLPRLGLLRRLHPGHRPAHRSHWGPRLPLWLHRWPQGLCQRRSLRGAG
HLHPRHVRQQGGSAAGPVRGRVHRQRDGLQRGERVPGPGRGLVGGCRVLGGAGPPFRGAH
RNAGLLRHALHRLRLRGHRRAAVPAPAAHRRRAGRPAWPQARHHRALPGPLVPLHPLRQP
RGLLPHPRLLAHSAETRPPPGDSCTTPDPRGSFVLQRFGLLA
NT seq 2829 nt   +upstreamnt  +downstreamnt
atggctcccctggccttggtggggttcgcgctcctcctgggggctcccccatgctcgggg
gcagccacaccgaccccctctctgccacctcccccagccaatgacagtgatgccagcacg
gaggcatgccagggctccaaccgctgccagccgggggtcctgctgcccgtctgggagccc
gacgacccatcgctgggtgacaaggcggcaagggcagtggtctactttgtagccatggtg
tatatgttcctgggtgtgtccatcattgccgaccgcttcatggcatccatcgaggtcatc
acatcaaaggagaaggagatcactatcaccaaggccaatggcgagaccagcgtgggcacc
gtccgcatctggaatgagaccgtgtccaacctcacactcatggccctgggctcctcggca
cccgagatcctgctgtctgtcatcgaggtctgtggccacaacttccaggcgggcgagcta
ggcccaggcaccatcgtaggcagcgctgccttcaacatgtttgtggtcattgcggtgtgc
gtctatgtcatcccggctggcgagagccgcaagatcaagcacttgagagtcttctttgtc
actgcctcttggagtatcttcgcctacgtctggctttatctcatccttgcggtcttttcc
ccaggtgtggtccaggtgtgggaggcgctgctgaccctggtcttcttcccggtgtgcgtg
gtgttcgcttggatggccgacaagcggctgctcttctacaagtacgtgtacaagcgctac
cgcaccgacccgcgcagcggcatcatcatcggcgccgagggcgacccccccaagagcatc
gaactggacggcacgttcgtgggcgccgaggcaccgggagaggtgggcggcctgggcccc
ggccccgccgaggcccgtgagctggacgccagccgccgcgaggtcatccagattctcaag
gacctgaagcagaagcaccctgacaaggacctggagcagctggtgggcatcgccaactac
tacgccctgctgcaccagcagaagagccgcgctttctaccgcatccaggccacgcggctg
atgaccggcgcgggcaacgtgctgcggcgacacgcggtggacgcctcgcgccgggcctcc
ccagccgacggccccggcgaggacgaggacgatggcgccagccacatcttcttcgagccc
agcctctaccactgcctggagaactgtggctcggtgctgctgtctgtcacctgccagggc
ggcgagggcaacagcaccttctacgtggactaccgcaccgaggacggctccgccaaggcc
ggctccgactatgagtacagcgagggcacgctggtgttcaagccaggcgagacgcagaag
gaactgcgcatcggcatcatcgacgacgacatctttgaggaggacgagcacttcttcgtg
cggctgctgaacctgcgagtgggggacgcgcagggcatgttcgagcccgacggcggcggg
cggcccaagggacggctggtggcgccgctgctggccaccgtcaccatcctcgacgacgac
cacgcaggcatcttctccttccaggaccgcctgctgcacgtgagcgagtgcatgggcacc
gtggacgtgcgcgtcgtgcgaagctctggcgcgcgcggcaccgtgcgcctcccctaccgc
acggtagacggcacggcgcgcggcggcggcgtacactacgaggacgcgtgcggcgagctg
gagtttggggacgacgagaccatgaaaactctgcaggtgaagatagttgatgacgaggaa
tatgaaaaaaaagataatttcttcatcgagctgggccagccgcagtggcttaagcgaggg
atttcagatcatggacccgaacttcacagagaagcaatctcactttctgtctgtctctcc
ccagctctgctgctcaatcaaggggatggggacaggaaactgacggctgaagaggaggag
gctcggagaatagcagagatgggcaagccggttcttggggaaaactgccggctggaggtc
atcatcgaggagtcatatgattttaagaacacagtggataaactcatcaagaaaacgaac
ttggctttggtgattggaacccattcgtggagggagcagtttttagaggcaattacggtg
agcgcaggtgctgttcgcctgcgtgccccccaccgagtattgccacggctgggcctgctt
cggcgtctgcatcctggtcatcggcctgctcaccgctctcattggggacctcgcctccca
ctttggctgcaccgttggcctcaaggactctgtcaacgccgtagtcttcgtggcgctggg
cacctccatccccgacacgttcgccagcaaggtggcagcgctgcaggaccagtgcgcgga
cgcgtccatcggcaacgtgacgggctccaacgcggtgaacgtgttcctgggcctgggcgt
ggcctggtcggtggctgccgtgtactgggcggtgcagggccgccctttcgaggtgcgcac
cggaacgctggccttctccgtcacgctcttcaccgtcttcgccttcgtgggcatcgccgt
gctgctgtaccggcgccggccgcacatcggcggcgagctgggcggcccgcgtggccccaa
gctcgccaccaccgcgctcttcctgggcctctggttcctctacatcctcttcgccagcct
cgaggcttactgccacatccgaggcttctagcgcattccgcagagactcggccaccccct
ggagacagctgcactactccggacccccgcggctccttcgtcctccagagattcggcctc
cttgcctga

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (12)   
   KEGG PATHWAY (12)   
Genome (1)   
   KEGG GENOME (1)   
Gene (95)   
   KEGG ORTHOLOGY (1)   
   RefGene (90)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   ENSEMBLRAPID (1)   
   OC (1)   
Protein sequence (7)   
   UniProt (1)   
   RefSeq(pep) (6)   
DNA sequence (6)   
   RefSeq(nuc) (6)   
Protein domain (3)   
   Pfam (3)   
All databases (127)   

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