KEGG   Hipposideros armiger (great roundleaf bat): 109385295
Entry
109385295         CDS       T04661                                 
Symbol
BACE1
Name
(RefSeq) beta-secretase 1 isoform X1
  KO
K04521  beta-site APP-cleaving enzyme 1 (memapsin 2) [EC:3.4.23.46]
Organism
hai  Hipposideros armiger (great roundleaf bat)
Pathway
hai05010  Alzheimer disease
Brite
KEGG Orthology (KO) [BR:hai00001]
 09160 Human Diseases
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    109385295 (BACE1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors [BR:hai01002]
    109385295 (BACE1)
Enzymes [BR:hai01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.23  Aspartic endopeptidases
    3.4.23.46  memapsin 2
     109385295 (BACE1)
Peptidases and inhibitors [BR:hai01002]
 Aspartic peptidases
  Family A1: pepsin family
   109385295 (BACE1)
SSDB
Motif
Pfam: Asp TAXi_C TAXi_N PE-PGRS_C
Other DBs
NCBI-GeneID: 109385295
NCBI-ProteinID: XP_019502961
EnsemblRapid: ENSHARG00000004044
UniProt: A0A8B7RPD8
Position
Unknown
AA seq 501 aa
MAQALSWLLLWMGSAVLPAHCTQPGIRLPLRSGLGGTPLGLRLPRDTDEELEEPGRSGSF
VEMVDNLRGKSGQGYYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPFLHRYYQRQLSST
YRDLRKGVYVPYTQGKWEGELGTDLVSIPHGPNVTVRANIAAITESDKFFINGSNWEGIL
GLAYAEIARPDDSLEPFFDSLVKQTHVPNLFSLQLCGAGFPLNQSEVLASVGGSMIIGGI
DPSLYTGSLWYTPIRREWYYEVIIVRVEINGQDLKMDCKEYNYDKSIVDSGTTNLRLPKK
VFEAAVKSIKAASSTEKFPDGFWLGEQLVCWQAGTTPWNIFPVISLYLMGEVTNQSFRIT
ILPQQYLRPVEDVATSQDDCYKFAISQSSTGTVMGAVIMEGFYVVFDRAHKRIGFAVSAC
HVHDEFRTAAVEGPFVTPDMEDCGYNIPQTDESTLMTIAYVMAAICALFMLPLCLMVCQW
RCLRCLRHQHDDFADDISLLK
NT seq 1506 nt   +upstreamnt  +downstreamnt
atggcccaagcactgtcctggcttctgctgtggatgggctcggcagtgctgcctgcccac
tgcacccagcctggcatcaggctacctctgcggagtgggcttggggggacacccctgggt
ctgaggcttccccgggacactgacgaggaactggaggagcctggccggagtggcagcttt
gtggagatggtggataacctgaggggcaagtctggtcagggctactacgtggagatgacc
gtgggcagccccccacagacgctcaacatcctggtggacacagggagcagtaactttgca
gtgggggctgccccccaccctttcctgcatcgctactaccagaggcagctgtccagcaca
taccgggacctccggaagggtgtgtatgtgccctacacccagggcaagtgggagggggag
ctgggcaccgacctggtgagcatcccccatggccccaatgtcactgtgcgtgccaacatc
gctgccatcactgaatcagacaagttcttcatcaatggctccaactgggaaggcatcctg
gggctggcctatgctgagatcgccaggcctgacgactccctggagcctttctttgactcc
ctggtaaagcagacccacgttcccaacctcttttccctgcagctctgtggtgctggcttc
cccctcaaccagtcagaggtgctggcctcagttggagggagcatgatcattgggggtatc
gacccctcgctgtacacgggcagcctctggtacacacccatccgtcgggagtggtattat
gaggtgatcattgtgcgggtagagatcaatggacaggatctgaaaatggactgcaaggag
tacaactatgacaagagcatcgtggacagtggcaccacgaaccttcgtttgcccaagaaa
gtgtttgaagctgcagtcaaatccatcaaagcagcctcctcgacggagaaattcccagac
ggcttctggcttggggaacagctggtgtgctggcaagcaggcacaaccccttggaacatt
ttcccagtcatctcactctacctaatgggtgaagttaccaatcagtccttccgcatcacc
attctcccacagcaatacctgcggccagtggaagacgtggccacgtcccaagacgactgc
tacaagtttgccatctcacagtcatccacgggcactgttatgggagctgttatcatggag
ggcttctacgttgtctttgatcgagcccacaaacgaattggctttgctgtcagtgcttgc
catgtgcatgatgagttcaggacggcagcggtggaaggcccctttgtcaccccggacatg
gaagactgtggctacaacattccacagacggatgaatcaacgctcatgaccatagcctat
gtcatggcggccatctgcgccctcttcatgctgccactctgcctcatggtgtgtcagtgg
cgctgcctccgctgtctgcgccatcagcatgatgactttgctgacgacatctccctgctg
aagtga

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (1)   
   KEGG PATHWAY (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (13)   
   KEGG ORTHOLOGY (1)   
   RefGene (8)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   ENSEMBLRAPID (1)   
   OC (1)   
Protein sequence (4)   
   UniProt (1)   
   RefSeq(pep) (3)   
DNA sequence (3)   
   RefSeq(nuc) (3)   
Protein domain (4)   
   Pfam (4)   
All databases (30)   

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