KEGG   Heterocephalus glaber (naked mole-rat): 101714626
Entry
101714626         CDS       T02812                                 
Symbol
Gsta4
Name
(RefSeq) glutathione S-transferase alpha 4
  KO
K00799  glutathione S-transferase [EC:2.5.1.18]
Organism
hgl  Heterocephalus glaber (naked mole-rat)
Pathway
hgl00480  Glutathione metabolism
hgl00980  Metabolism of xenobiotics by cytochrome P450
hgl00982  Drug metabolism - cytochrome P450
hgl00983  Drug metabolism - other enzymes
hgl01100  Metabolic pathways
hgl01524  Platinum drug resistance
hgl05200  Pathways in cancer
hgl05204  Chemical carcinogenesis - DNA adducts
hgl05207  Chemical carcinogenesis - receptor activation
hgl05208  Chemical carcinogenesis - reactive oxygen species
hgl05225  Hepatocellular carcinoma
hgl05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:hgl00001]
 09100 Metabolism
  09106 Metabolism of other amino acids
   00480 Glutathione metabolism
    101714626 (Gsta4)
  09111 Xenobiotics biodegradation and metabolism
   00980 Metabolism of xenobiotics by cytochrome P450
    101714626 (Gsta4)
   00982 Drug metabolism - cytochrome P450
    101714626 (Gsta4)
   00983 Drug metabolism - other enzymes
    101714626 (Gsta4)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    101714626 (Gsta4)
   05204 Chemical carcinogenesis - DNA adducts
    101714626 (Gsta4)
   05207 Chemical carcinogenesis - receptor activation
    101714626 (Gsta4)
   05208 Chemical carcinogenesis - reactive oxygen species
    101714626 (Gsta4)
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    101714626 (Gsta4)
  09166 Cardiovascular disease
   05418 Fluid shear stress and atherosclerosis
    101714626 (Gsta4)
  09176 Drug resistance: antineoplastic
   01524 Platinum drug resistance
    101714626 (Gsta4)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters [BR:hgl02000]
    101714626 (Gsta4)
Enzymes [BR:hgl01000]
 2. Transferases
  2.5  Transferring alkyl or aryl groups, other than methyl groups
   2.5.1  Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
    2.5.1.18  glutathione transferase
     101714626 (Gsta4)
Transporters [BR:hgl02000]
 Other transporters
  Pores ion channels [TC:1]
   101714626 (Gsta4)
SSDB
Motif
Pfam: GST_C_3 GST_C GST_N GST_C_2
Other DBs
NCBI-GeneID: 101714626
NCBI-ProteinID: XP_012922539
Position
Un
AA seq 261 aa
MAARLKLHCPNGRGCMEPVRWVLAAARVEVPCPWAFILGNHLLSQQVPMVEIDGXKLVQT
RSILHNIAEKHQLFSRDFKDRTLYCGLLWHCCYALADYLPSAARPICFIRIDMYVEGTLD
LLELLIMYPFLKSEDQQKEVFHMGQKAIIRYFLVFEKVGGREAQEHSITIPQEYILQVLR
GHGQNFLVGNQLSLADVILLQTILALEEKIPNVLSAFPFLQEYTVKLSNIPTIKRFLEPG
SKKKPSPDDFYVRTVHNIFVP
NT seq 786 nt   +upstreamnt  +downstreamnt
atggcagcgaggctcaagctgcactgccccaacgggagaggctgcatggagcccgtcaga
tgggtcctggccgccgccagagtagaggtaccctgcccctgggctttcatcctaggtaac
cacctgctctcccaacaagtgcccatggttgaaatcgatgggnataagttggtgcagacc
cgaagcatcctccacaacatagctgaaaagcaccagctcttcagcagggacttcaaggac
agaaccctgtactgtggcctcctttggcactgctgttatgccttggctgattatctacct
tctgcagcacgtcccatctgctttataaggattgacatgtacgtggaggggacgctggat
ctcttggaactgcttatcatgtatcctttcttaaaatcagaggatcaacaaaaggaagtg
tttcacatgggccagaaggctataattagatacttcctagtgtttgaaaaggtgggtggc
agagaagcccaagagcacagcataaccataccacaagagtatatcctacaggttttaagg
ggtcatggacaaaactttcttgttggtaatcagctgagccttgcagacgtgattctactc
caaaccattttggctctggaagagaaaattcctaatgtcctatctgcatttcctttcctc
caggaatacacagtgaaattaagtaatatccctacaattaagagatttcttgaacctgga
agcaagaagaagccttcccctgatgacttctatgtgagaactgtccacaacatctttgtg
ccatga

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (12)   
   KEGG PATHWAY (12)   
Chemical substance (45)   
   KEGG COMPOUND (45)   
Chemical reaction (23)   
   KEGG ENZYME (1)   
   KEGG REACTION (22)   
Genome (1)   
   KEGG GENOME (1)   
Gene (18)   
   KEGG ORTHOLOGY (1)   
   RefGene (14)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (4)   
   Pfam (4)   
All databases (108)   

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