KEGG   Heterocephalus glaber (naked mole-rat): 101714605
Entry
101714605         CDS       T02812                                 
Symbol
Adcy9
Name
(RefSeq) adenylate cyclase 9
  KO
K08049  adenylate cyclase 9 [EC:4.6.1.1]
Organism
hgl  Heterocephalus glaber (naked mole-rat)
Pathway
hgl00230  Purine metabolism
hgl01100  Metabolic pathways
hgl01522  Endocrine resistance
hgl04015  Rap1 signaling pathway
hgl04020  Calcium signaling pathway
hgl04022  cGMP-PKG signaling pathway
hgl04024  cAMP signaling pathway
hgl04062  Chemokine signaling pathway
hgl04072  Phospholipase D signaling pathway
hgl04114  Oocyte meiosis
hgl04211  Longevity regulating pathway
hgl04213  Longevity regulating pathway - multiple species
hgl04261  Adrenergic signaling in cardiomyocytes
hgl04270  Vascular smooth muscle contraction
hgl04371  Apelin signaling pathway
hgl04540  Gap junction
hgl04611  Platelet activation
hgl04713  Circadian entrainment
hgl04714  Thermogenesis
hgl04723  Retrograde endocannabinoid signaling
hgl04724  Glutamatergic synapse
hgl04725  Cholinergic synapse
hgl04727  GABAergic synapse
hgl04750  Inflammatory mediator regulation of TRP channels
hgl04911  Insulin secretion
hgl04912  GnRH signaling pathway
hgl04913  Ovarian steroidogenesis
hgl04914  Progesterone-mediated oocyte maturation
hgl04915  Estrogen signaling pathway
hgl04916  Melanogenesis
hgl04918  Thyroid hormone synthesis
hgl04921  Oxytocin signaling pathway
hgl04923  Regulation of lipolysis in adipocytes
hgl04925  Aldosterone synthesis and secretion
hgl04926  Relaxin signaling pathway
hgl04927  Cortisol synthesis and secretion
hgl04928  Parathyroid hormone synthesis, secretion and action
hgl04934  Cushing syndrome
hgl04935  Growth hormone synthesis, secretion and action
hgl04961  Endocrine and other factor-regulated calcium reabsorption
hgl04962  Vasopressin-regulated water reabsorption
hgl04970  Salivary secretion
hgl04971  Gastric acid secretion
hgl04972  Pancreatic secretion
hgl04976  Bile secretion
hgl05032  Morphine addiction
hgl05163  Human cytomegalovirus infection
hgl05166  Human T-cell leukemia virus 1 infection
hgl05200  Pathways in cancer
hgl05207  Chemical carcinogenesis - receptor activation
hgl05414  Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:hgl00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    101714605 (Adcy9)
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    101714605 (Adcy9)
   04371 Apelin signaling pathway
    101714605 (Adcy9)
   04020 Calcium signaling pathway
    101714605 (Adcy9)
   04072 Phospholipase D signaling pathway
    101714605 (Adcy9)
   04024 cAMP signaling pathway
    101714605 (Adcy9)
   04022 cGMP-PKG signaling pathway
    101714605 (Adcy9)
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    101714605 (Adcy9)
  09144 Cellular community - eukaryotes
   04540 Gap junction
    101714605 (Adcy9)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    101714605 (Adcy9)
   04062 Chemokine signaling pathway
    101714605 (Adcy9)
  09152 Endocrine system
   04911 Insulin secretion
    101714605 (Adcy9)
   04923 Regulation of lipolysis in adipocytes
    101714605 (Adcy9)
   04912 GnRH signaling pathway
    101714605 (Adcy9)
   04913 Ovarian steroidogenesis
    101714605 (Adcy9)
   04915 Estrogen signaling pathway
    101714605 (Adcy9)
   04914 Progesterone-mediated oocyte maturation
    101714605 (Adcy9)
   04921 Oxytocin signaling pathway
    101714605 (Adcy9)
   04926 Relaxin signaling pathway
    101714605 (Adcy9)
   04935 Growth hormone synthesis, secretion and action
    101714605 (Adcy9)
   04918 Thyroid hormone synthesis
    101714605 (Adcy9)
   04928 Parathyroid hormone synthesis, secretion and action
    101714605 (Adcy9)
   04916 Melanogenesis
    101714605 (Adcy9)
   04925 Aldosterone synthesis and secretion
    101714605 (Adcy9)
   04927 Cortisol synthesis and secretion
    101714605 (Adcy9)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    101714605 (Adcy9)
   04270 Vascular smooth muscle contraction
    101714605 (Adcy9)
  09154 Digestive system
   04970 Salivary secretion
    101714605 (Adcy9)
   04971 Gastric acid secretion
    101714605 (Adcy9)
   04972 Pancreatic secretion
    101714605 (Adcy9)
   04976 Bile secretion
    101714605 (Adcy9)
  09155 Excretory system
   04962 Vasopressin-regulated water reabsorption
    101714605 (Adcy9)
   04961 Endocrine and other factor-regulated calcium reabsorption
    101714605 (Adcy9)
  09156 Nervous system
   04724 Glutamatergic synapse
    101714605 (Adcy9)
   04727 GABAergic synapse
    101714605 (Adcy9)
   04725 Cholinergic synapse
    101714605 (Adcy9)
   04723 Retrograde endocannabinoid signaling
    101714605 (Adcy9)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    101714605 (Adcy9)
  09149 Aging
   04211 Longevity regulating pathway
    101714605 (Adcy9)
   04213 Longevity regulating pathway - multiple species
    101714605 (Adcy9)
  09159 Environmental adaptation
   04713 Circadian entrainment
    101714605 (Adcy9)
   04714 Thermogenesis
    101714605 (Adcy9)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    101714605 (Adcy9)
   05207 Chemical carcinogenesis - receptor activation
    101714605 (Adcy9)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    101714605 (Adcy9)
   05163 Human cytomegalovirus infection
    101714605 (Adcy9)
  09165 Substance dependence
   05032 Morphine addiction
    101714605 (Adcy9)
  09166 Cardiovascular disease
   05414 Dilated cardiomyopathy
    101714605 (Adcy9)
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    101714605 (Adcy9)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    101714605 (Adcy9)
Enzymes [BR:hgl01000]
 4. Lyases
  4.6  Phosphorus-oxygen lyases
   4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)
    4.6.1.1  adenylate cyclase
     101714605 (Adcy9)
SSDB
Motif
Pfam: Guanylate_cyc Adcy_cons_dom AC_N
Other DBs
NCBI-GeneID: 101714605
NCBI-ProteinID: XP_004864825
Position
Un
AA seq 1372 aa
MASPPHQQLLHHHSTEVSCDSSGDSNSVRVKINPKQLSSNSHPKHCKYSISSSCSSSGDS
GGLPRRVGGRSRLRRQRKLPQLFERASSRWWDPKFDSVNLEEACLERCFPQTQRRFRYAL
FYVGFACLLWSIYFAVHMRSKLIVMMAPPLCFLVVCVGFFLFTFTKLYTRHYSWTSLAFT
LLVFALTLAAQFQVLTPLSGRVDSSNRTPTARPADICLSQVGSFSMCIEVLFLLYTVMHL
PLYLSLFLGVAYSVLFETFGYHFRDEDCFPSPEVPALHWELLSRALLHVCIHAIGIHLFV
MSQVRSRSTFLKVGQSIMHGKDLEVEKALKERMIHSVMPRIIADDLMKQGDEESENSVKR
HATSSPKNRKKKSSIQKAPIAFRPFKMQQIEEVSILFADIVGFTKMSANKSAHALVGLLN
DLFGRFDRLCEETKCEKISTLGDCYYCVAGCPEPRADHAYCCIEMGLGMIKAIEQFCQEK
KEMVNMRVGVHTGTVLCGILGMRRFKFDVWSNDVNLANLMEQLGVAGKVHISEATAKYLD
DRYKMEDGKVIERLGQSVVADQLRGLKTYLISGQRAKESHCSCAEALLSGFEAIDGSRVS
SGPRGQGTASSGSVSDLAQTVKTFDNLKTCPSCGITFAPKSEAGAEGGAVQNGCQDESKT
STKVTSSWLLFLSVPLLAHPPKASGGPNSKAQNGLLSPPQEEKLTNSQTSLCEILQEKGR
WAGVSLDQSALLPLRFKNIREKTDAHFVDVIKEDSLMKDYFFKPPINQFSLNFLDQELER
SYRTSYQEEVIKNSPVKTFASATFSSLLDVLLSTTVFLILSVTCFLKYGATAMPPPPAAL
AIFGAALLLEVLSLVVSIRMVFFLEDVMACTQRLLEWIAGWLPRHCIGAVLVSLPALAVY
SHITSEFETNVHFTVFTSSAVLVAVVHYCNFCQLSSWMRSSLATIVGAGPLLLLYISLCP
DSSIAISPLDVAQNFSAERNPCNSSLTQDSRRPTSLMGKELILAFFLLLLLVWFLNREFE
VSYRLHYHGDVEADLHRTKIQSMRDQADWLLRNIIPYHVAEQLKVSQTYSKNHDSGGVIF
ASIVNFSEFYEENYEGGKECYRVLNELIGDFDELLSKPDYNNIEKIKTIGATYMAASGLN
TAQCQEGSHPQEHLRILFEFAKEMMRVVDDFNNNMLWFNFKLRVGFNHGPLTAGVIGTTK
LLYDIWGDTVNIASRMDTTGVECRIQVSEESYRVLSKMGYDFDYRGTVNVKGKGQMKTYL
YPKCMDNGVVPQHQLSISPDIRVQVDGSIGRSPTDEIANLVPSVQYLDKTSLGSDDNTQA
KNTHLSSKRPWKEPIRVEERCRFGKAIEKDDCEDMGMEETNEFTKLNVSKSV
NT seq 4119 nt   +upstreamnt  +downstreamnt
atggcttccccgccccaccagcagctgctgcatcaccacagtactgaggtgagctgcgac
tccagcggagacagcaacagcgtaagggtcaagataaaccccaagcagctatcctctaac
agccaccccaagcactgcaagtacagcatctcttccagctgtagcagctctggggactcc
ggggggcttcctcggagggtgggcggcaggagccgccttcgcaggcagaggaagctgccc
cagctgttcgagcgggcatccagccggtggtgggatcccaagttcgactcggtgaacctg
gaggaagcctgcctggagcgctgcttcccgcagacccagcgccgcttccggtatgcactc
ttctacgtgggcttcgcctgccttctctggagcatctatttcgctgtccacatgaggtcc
aaactgattgtcatgatggctccccctctgtgcttcctggtggtgtgcgtgggctttttt
ctatttaccttcaccaagctgtacacccggcattactcgtggacctcactggctttcacc
ctgctggtgttcgccttgactctggctgcgcaatttcaggttttgacgcctctctcagga
cgagttgacagctccaatcgtactcctacagccaggcccgcagacatttgcctgtctcaa
gtggggagcttttccatgtgcatcgaagtgctctttttgctttatactgtcatgcactta
cctttgtacttgagcttgtttttgggggtggcctattctgtcctttttgagacctttggc
tatcatttccgagatgaagactgcttcccctctcctgaagtcccggccctgcactgggag
ttgctgagccgggccctgctccacgtgtgcattcatgccattgggatccacctatttgtc
atgtctcaggtgaggtccaggagcaccttcctcaaggtgggacaatccatcatgcacgga
aaagacctagaagtagaaaaagccctcaaagagaggatgattcattctgttatgccaaga
attattgctgatgacttaatgaaacagggggatgaggagagtgagaattctgtcaagagg
catgctacttccagccccaaaaacaggaagaaaaagtcctccatacagaaagctccaata
gcattccgcccttttaagatgcagcagattgaagaagtcagtattttatttgcagatatt
gtgggcttcaccaagatgagtgccaacaagtctgctcatgccctggtgggtctcctcaac
gacctgtttggtcgctttgaccggctgtgtgaggagaccaaatgtgagaaaatcagcaca
ctgggagactgttactattgtgtggcagggtgtcctgagccccgagcagaccatgcctac
tgctgtatcgaaatgggcttagggatgataaaagccattgaacagttctgccaagagaag
aaagaaatggtgaacatgcgagtcggggttcatacggggactgtgttgtgtggcatcttg
ggtatgaggaggtttaaatttgatgtgtggtccaatgatgtaaacttggccaatctcatg
gagcagctgggagtggctggtaaagttcacatttctgaggccactgcaaaatacttagat
gaccggtacaaaatggaagatgggaaagttattgaacgccttggccagagtgtggttgct
gaccagttgagaggtttgaagacatacctgatttcgggtcagagagccaaggaatctcat
tgcagctgtgcagaggccttgctttctggctttgaggccattgacggttcacgggtgtcc
tcaggccctaggggacagggaacagcatcatcagggagtgtcagtgacttggcgcagact
gtcaaaacctttgataaccttaagacctgcccttcatgtggaattacatttgctcccaag
tcagaagctggtgcagaaggaggagctgtgcaaaacggctgtcaagacgagtctaagacc
agcaccaaggtaacaagctcatggctgttgttcctgtcagttcctctcctggcgcatcca
cctaaggcttctggaggacctaattccaaagctcagaatggacttctgagccctccccaa
gaggaaaagctcaccaacagtcagacctccctgtgcgagatccttcaggagaagggaagg
tgggcaggtgtgagcttggaccaatcagccctcctcccactgaggttcaagaacatccgt
gagaaaacggatgcccattttgtggatgttatcaaagaagacagcctcatgaaagattat
tttttcaagccacccattaatcagttcagtctgaacttcctggatcaggagctggagcga
tcctataggaccagctatcaggaagaggtcataaagaattctcctgtgaaaacttttgcc
agtgccaccttcagctccctcctggatgtgttgctgtccacaacagtattcctgattctc
tctgtcacctgcttcctgaagtatggagccactgccatgcctcccccaccagctgccctg
gccatcttcggtgcagccttgctgctggaagtactgtcccttgtggtgtccatcaggatg
gtgttcttcctggaggatgtcatggcatgcacacagcgcctgttggagtggatcgctggc
tggctacctcgccattgcattggggctgtcctggtatccctgcctgcccttgctgtctat
tcacacatcacctccgagtttgagacaaatgtacatttcaccgtgttcaccagctcagcc
gtgttagtggctgtcgtgcactactgtaacttctgccagctcagctcctggatgaggtcc
tcccttgctaccatcgtgggggccgggccactgcttctgctctacatctccctgtgtcca
gacagttccatagcaatttcacccctggatgtggcacagaacttcagtgccgagaggaac
ccatgcaacagctccctgacacaggacagcaggaggccaaccagccttatgggtaaggag
ctcatccttgccttctttctcctgctcctgctggtctggttcctgaaccgagagtttgaa
gtcagctatcgcctgcactaccatggggatgtggaagcagaccttcaccgcaccaagatc
cagagcatgagggaccaggctgactggctgctgaggaatatcatcccctaccacgtggcc
gagcagctgaaggtctcccagacttactccaagaaccacgacagtggaggagtgatcttt
gccagcatcgtcaacttcagtgagttctacgaggagaactacgaagggggcaaggagtgc
taccgagtcctcaatgagctgattggtgacttcgatgagctcctgagcaagccagactac
aataacattgagaagattaagaccatcggggccacatacatggcagcatcagggctaaat
acagcccaatgccaagagggcagtcacccacaggagcaccttcggatcctgtttgagttt
gccaaggagatgatgcgtgtggtggatgacttcaacaacaacatgctgtggttcaacttc
aagctcagggttggctttaaccatgggccgctcacagcaggtgtcattggtaccaccaag
ctgctctatgatatctggggggacacggtcaacattgccagcaggatggacaccactggg
gttgagtgtcgcatccaggtgagtgaggagagctaccgtgtgctgagcaaaatgggctat
gattttgactaccggggaacagtgaatgtcaagggtaaagggcagatgaaaacctacctt
tacccaaagtgcatggacaatggggtggtgccacagcaccagctctccatctccccagac
atccgtgtccaggtggatggcagcatcggacggtctcccacagatgagattgccaacctg
gtgccttctgtccagtatttagacaagacatccttgggctctgatgacaacacgcaagcc
aagaacacacacctgtcttctaagagaccctggaaagagcccatcagagtggaagaaagg
tgtcgatttggcaaagccatagagaaagatgactgtgaagacatgggaatggaagaaacc
aatgaattcaccaagctcaacgtctcaaagagtgtgtaa

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (51)   
   KEGG PATHWAY (51)   
Chemical substance (5)   
   KEGG COMPOUND (5)   
Chemical reaction (3)   
   KEGG ENZYME (1)   
   KEGG REACTION (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (20)   
   KEGG ORTHOLOGY (1)   
   RefGene (16)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (3)   
   RefSeq(pep) (3)   
DNA sequence (5)   
   RefSeq(nuc) (3)   
   GenBank (1)   
   EMBL (1)   
Protein domain (3)   
   Pfam (3)   
All databases (93)   

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