KEGG   Heterocephalus glaber (naked mole-rat): 101712604
Entry
101712604         CDS       T02812                                 
Symbol
Hmgcs1
Name
(RefSeq) 3-hydroxy-3-methylglutaryl-CoA synthase 1
  KO
K01641  hydroxymethylglutaryl-CoA synthase [EC:2.3.3.10]
Organism
hgl  Heterocephalus glaber (naked mole-rat)
Pathway
hgl00280  Valine, leucine and isoleucine degradation
hgl00650  Butanoate metabolism
hgl00900  Terpenoid backbone biosynthesis
hgl01100  Metabolic pathways
hgl03320  PPAR signaling pathway
Module
hgl_M00095  C5 isoprenoid biosynthesis, mevalonate pathway
Brite
KEGG Orthology (KO) [BR:hgl00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00650 Butanoate metabolism
    101712604 (Hmgcs1)
  09105 Amino acid metabolism
   00280 Valine, leucine and isoleucine degradation
    101712604 (Hmgcs1)
  09109 Metabolism of terpenoids and polyketides
   00900 Terpenoid backbone biosynthesis
    101712604 (Hmgcs1)
 09150 Organismal Systems
  09152 Endocrine system
   03320 PPAR signaling pathway
    101712604 (Hmgcs1)
Enzymes [BR:hgl01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.3  Acyl groups converted into alkyl groups on transfer
    2.3.3.10  hydroxymethylglutaryl-CoA synthase
     101712604 (Hmgcs1)
SSDB
Motif
Pfam: HMG_CoA_synt_C HMG_CoA_synt_N Cullin
Other DBs
NCBI-GeneID: 101712604
NCBI-ProteinID: XP_004848617
UniProt: G5BCR6
Position
Un
AA seq 520 aa
MPGSLPLNAEACWPKDVGIVALEIYFPSQYVDQTQLEKYDGVDAGKYTIGLGQAKMGFCT
DREDINSLCLTVVQNLMERHSLSYDCIGRLEVGTETIIDKSKSVKSNLMQLFEESGNTDI
EGIDTTNACYGGTAAVFNAVNWIESSSWDGRYALVVAGDIAIYATGNARPTGGAGAVALL
IGPNAPLIFDRGLRGTHMQHAYDFYKPDMLSEYPIVDGKLSIQCYLSALDRCYSVYRKKI
RAQWQKEGNDKDFTLNDFGFMIFHSPYCKLVQKSLARMMLNDFLNDQNRDKNTIYSGLEA
FGDVKLEDTYFDRDVEKAFMKASSELFNQKTKASLLVSNQNGNMYTSSVYGSLASVLAQY
SPQQLAGKRIGVFSYGSGLAATLYSLRVTQDATPGSGLDKITAGLCDLKSRLDSRTCVAP
DVFAESMKLREDTHHLANYIPQSSVDSLFEGTWYLVRVDEKHRRTYARRPSPNDDTLDEG
VGLVHSNTATEHIPSPAKKVPRLPTTGTEPEAAVISNGEH
NT seq 1563 nt   +upstreamnt  +downstreamnt
atgcctgggtcacttcctttgaatgcagaagcttgttggccaaaagatgtgggaattgtt
gcccttgagatctattttccttctcaatatgttgatcaaacgcagttggaaaaatatgat
ggtgttgatgctggcaagtataccattggcttgggccaggcaaagatgggcttctgcaca
gatcgagaggacatcaactctctttgcctgactgtggttcagaatctgatggaaagacat
agtctttcctatgactgcattgggcggctcgaggttggaacagagacaatcatcgacaaa
tcaaagtctgtgaagagtaatttgatgcagctgtttgaggagtctgggaatacagacata
gaaggaatagatacgactaacgcatgctatggaggcacggctgctgtcttcaatgctgtt
aactggattgagtctagctcttgggatggacggtatgctctggtagttgcaggagatatt
gctatatatgccacaggaaatgccagacctactggtggagctggagctgtggctctgcta
attggaccaaatgctcctttaatttttgaccgagggcttcgtggaacacatatgcagcat
gcctatgacttttacaagcctgatatgctctctgaatatcctatagtagatggaaaactc
tctatacagtgctacctcagtgcattagatcgctgctattctgtctaccgtaaaaagatc
cgtgcccagtggcagaaagagggaaatgataaagattttaccttgaatgattttggcttc
atgatctttcactcaccatattgtaaactggttcagaaatctctagctcggatgatgctg
aatgatttccttaatgaccagaacagagataaaaatactatctatagtggactggaagcc
tttggggatgttaaattagaagatacttactttgacagagatgtagaaaaggcatttatg
aaggccagttctgaactctttaatcagaaaacaaaggcttctttgcttgtatcaaatcaa
aatggaaatatgtatacatcttcagtatatggttcccttgcttctgttttagcacagtac
tcacctcagcaattggcaggaaagaggattggagtattctcttatggttctggtttggct
gccaccctgtattctcttagagtcacgcaagatgccacaccagggtctggtcttgataaa
ataacagcaggtttatgtgatcttaaatcacggcttgactcaagaacttgtgtagcacct
gatgtctttgctgaaagcatgaagctcagagaggacactcatcacttggccaactatatt
ccccagagttcagtagattcactctttgaagggacatggtacctagttagagtggatgaa
aagcacagaagaacttatgctcgacgcccctctccaaatgatgacactttggatgaggga
gtaggacttgttcattcaaacacagcaactgagcatatcccaagccctgctaagaaagtg
ccaagacttcccacaacaggaacagaacctgaagcagctgtcattagtaatggggaacat
taa

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (8)   
   KEGG PATHWAY (5)   
   KEGG MODULE (3)   
Chemical substance (5)   
   KEGG COMPOUND (5)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (4)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (4)   
   UniProt (1)   
   RefSeq(pep) (3)   
DNA sequence (5)   
   RefSeq(nuc) (3)   
   GenBank (1)   
   EMBL (1)   
Protein domain (3)   
   Pfam (3)   
All databases (34)   

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