KEGG H.sapiens: 189

Homo sapiens (human): 189

Entry

189 CDS H.sapiens

Gene name AGXT

Definition alanine-glyoxylate aminotransferase (EC:2.6.1.44 2.6.1.51)

Orthology K00830 alanine--glyoxylate transaminase / serine--pyruvate
aminotransferase [EC:2.6.1.44 2.6.1.51]

Pathway hsa00250 Alanine, aspartate and glutamate metabolism
hsa00260 Glycine, serine and threonine metabolism
hsa01100 Metabolic pathways
hsa04146 Peroxisome

Disease H00117 Primary hyperoxaluria (HP)

Class Metabolism; Amino Acid Metabolism; Alanine, aspartate and glutamate
metabolism [PATH:hsa00250]
Metabolism; Amino Acid Metabolism; Glycine, serine and threonine
metabolism [PATH:hsa00260]
Cellular Processes; Transport and Catabolism; Peroxisome
[PATH:hsa04146]

SSDB

Motif Pfam: Aminotran_5 Aminotran_1_2 AlaDh_PNT_C
PROSITE: AA_TRANSFER_CLASS_5

Other DBs NCBI-GI: 4557289
NCBI-GeneID: 189
OMIM: 604285
HGNC: 341
HPRD: 05048
Ensembl: ENSG00000172482
UniProt: P21549

Structure

PDB: 1J04 1H0C

Position 2q36-q37

AA seq 392 aa
MASHKLLVTPPKALLKPLSIPNQLLLGPGPSNLPPRIMAAGGLQMIGSMSKDMYQIMDEI
KEGIQYVFQTRNPLTLVISGSGHCALEAALVNVLEPGDSFLVGANGIWGQRAVDIGERIG
ARVHPMTKDPGGHYTLQEVEEGLAQHKPVLLFLTHGESSTGVLQPLDGFGELCHRYKCLL
LVDSVASLGGTPLYMDRQGIDILYSGSQKALNAPPGTSLISFSDKAKKKMYSRKTKPFSF
YLDIKWLANFWGCDDQPRMYHHTIPVISLYSLRESLALIAEQGLENSWRQHREAAAYLHG
RLQALGLQLFVKDPALRLPTVTTVAVPAGYDWRDIVSYVIDHFDIEIMGGLGPSTGKVLR
IGLLGCNATRENVDRVTEALRAALQHCPKKKL

NT seq 1179 nt +upstreamnt +downstreamnt
atggcctctcacaagctgctggtgaccccccccaaggccctgctcaagcccctctccatc
cccaaccagctcctgctggggcctggtccttccaacctgcctcctcgcatcatggcagcc
ggggggctgcagatgatcgggtccatgagcaaggatatgtaccagatcatggacgagatc
aaggaaggcatccagtacgtgttccagaccaggaacccactcacactggtcatctctggc
tcgggacactgtgccctggaggccgccctggtcaatgtgctggagcctggggactccttc
ctggttggggccaatggcatttgggggcagcgagccgtggacatcggggagcgcatagga
gcccgagtgcacccgatgaccaaggaccctggaggccactacacactgcaggaggtggag
gagggcctggcccagcacaagccagtgctgctgttcttaacccacggggagtcgtccacc
ggcgtgctgcagccccttgatggcttcggggaactctgccacaggtacaagtgcctgctc
ctggtggattcggtggcatccctgggcgggacccccctttacatggaccggcaaggcatc
gacatcctgtactcgggctcccagaaggccctgaacgcccctccagggacctcgctcatc
tccttcagtgacaaggccaaaaagaagatgtactcccgcaagacgaagcccttctccttc
tacctggacatcaagtggctggccaacttctggggctgtgacgaccagcccaggatgtac
catcacacaatccccgtcatcagcctgtacagcctgagagagagcctggccctcattgcg
gaacagggcctggagaacagctggcgccagcaccgcgaggccgcggcgtatctgcatggg
cgcctgcaggcactggggctgcagctcttcgtgaaggacccggcgctccggcttcccaca
gtcaccactgtggctgtacccgctggctatgactggagagacatcgtcagctacgtcata
gaccacttcgacattgagatcatgggtggccttgggccctccacggggaaggtgctgcgg
atcggcctgctgggctgcaatgccacccgcgagaatgtggaccgcgtgacggaggccctg
agggcggccctgcagcactgccccaagaagaagctgtga

All links

Pathway (4)   
   KEGG PATHWAY (4)   
Disease (2)   
   KEGG DISEASE (1)   
   OMIM (1)   
Chemical reaction (2)   
   KEGG ENZYME (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (11)   
   KEGG ORTHOLOGY (1)   
   NCBI-Gene (1)   
   NCBI-GI (5)   
   UNIGENE (1)   
   HGNC (1)   
   HPRD (1)   
   ENSEMBL-HSA (1)   
Protein sequence (4)   
   UniProt (1)   
   RefSeq(pep) (1)   
   IPI (2)   
DNA sequence (11)   
   RefSeq(nuc) (1)   
   GenBank (5)   
   EMBL (5)   
3D Structure (2)   
   PDB (2)   
Protein domain (4)   
   Pfam (3)   
   PROSITE (1)   
All databases (41)

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