KEGG H.sapiens: 2584

Homo sapiens (human): 2584

Entry

2584 CDS H.sapiens

Gene name GALK1

Definition galactokinase 1 (EC:2.7.1.6)

Orthology K00849 galactokinase [EC:2.7.1.6]

Pathway hsa00052 Galactose metabolism
hsa00520 Amino sugar and nucleotide sugar metabolism
hsa01100 Metabolic pathways

Disease H00070 Galactosemia

Class Metabolism; Carbohydrate Metabolism; Galactose metabolism
[PATH:hsa00052]
Metabolism; Carbohydrate Metabolism; Amino sugar and nucleotide
sugar metabolism [PATH:hsa00520]

SSDB

Motif Pfam: GalKase_gal_bdg GHMP_kinases_C GHMP_kinases_N HAMP
PROSITE: GHMP_KINASES_ATP GALACTOKINASE

Other DBs NCBI-GI: 4503895
NCBI-GeneID: 2584
OMIM: 604313
HGNC: 4118
HPRD: 05057
Ensembl: ENSG00000108479
UniProt: P51570

Structure

PDB: 1WUU

Position 17q24

AA seq 392 aa
MAALRQPQVAELLAEARRAFREEFGAEPELAVSAPGRVNLIGEHTDYNQGLVLPMALELM
TVLVGSPRKDGLVSLLTTSEGADEPQRLQFPLPTAQRSLEPGTPRWANYVKGVIQYYPAA
PLPGFSAVVVSSVPLGGGLSSSASLEVATYTFLQQLCPDSGTIAARAQVCQQAEHSFAGM
PCGIMDQFISLMGQKGHALLIDCRSLETSLVPLSDPKLAVLITNSNVRHSLASSEYPVRR
RQCEEVARALGKESLREVQLEELEAARDLVSKEGFRRARHVVGEIRRTAQAAAALRRGDY
RAFGRLMVESHRSLRDDYEVSCPELDQLVEAALAVPGVYGSRMTGGGFGGCTVTLLEASA
APHAMRHIQEHYGGTATFYLSQAADGAKVLCL

NT seq 1179 nt +upstreamnt +downstreamnt
atggctgctttgagacagccccaggtcgcggagctgctggccgaggcccggcgagccttc
cgggaggagttcggggccgagcccgagctggccgtgtcagcgccgggccgcgtcaacctc
atcggggaacacacggactacaaccagggcctggtgctgcctatggctctggagctcatg
acggtgctggtgggcagcccccgcaaggatgggctggtgtctctcctcaccacctctgag
ggtgccgatgagccccagcggctgcagtttccactgcccacagcccagcgctcgctggag
cctgggactcctcggtgggccaactatgtcaagggagtgattcagtactacccagctgcc
cccctccctggcttcagtgcagtggtggtcagctcagtgcccctggggggtggcctgtcc
agctcagcatccttggaagtggccacgtacaccttcctccagcagctctgtccagactcg
ggcacaatagctgcccgcgcccaggtgtgtcagcaggccgagcacagcttcgcagggatg
ccctgtggcatcatggaccagttcatctcacttatgggacagaaaggccacgcgctgctc
attgactgcaggtccttggagaccagcctggtgccactctcggaccccaagctggccgtg
ctcatcaccaactctaatgtccgccactccctggcctccagcgagtaccctgtgcggcgg
cgccaatgtgaagaagtggcccgggcgctgggcaaggaaagcctccgggaggtacaactg
gaagagctagaggctgccagggacctggtgagcaaagagggcttccggcgggcccggcac
gtggtgggggagattcggcgcacggcccaggcagcggccgccctgagacgtggcgactac
agagcctttggccgcctcatggtggagagccaccgctcactcagagacgactatgaggtg
agctgcccagagctggaccagctggtggaggctgcgcttgctgtgcctggggtttatggc
agccgcatgacgggcggtggcttcggtggctgcacggtgacactgctggaggcctccgct
gctccccacgccatgcggcacatccaggagcactacggcgggactgccaccttctacctc
tctcaagcagccgatggagccaaggtgctgtgcttgtga

All links

Pathway (3)   
   KEGG PATHWAY (3)   
Disease (2)   
   KEGG DISEASE (1)   
   OMIM (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (10)   
   KEGG ORTHOLOGY (1)   
   NCBI-Gene (1)   
   NCBI-GI (4)   
   UNIGENE (1)   
   HGNC (1)   
   HPRD (1)   
   ENSEMBL-HSA (1)   
Protein sequence (5)   
   UniProt (1)   
   RefSeq(pep) (1)   
   IPI (3)   
DNA sequence (9)   
   RefSeq(nuc) (1)   
   GenBank (4)   
   EMBL (4)   
3D Structure (1)   
   PDB (1)   
Protein domain (6)   
   Pfam (4)   
   PROSITE (2)   
All databases (38)

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