KEGG   Homo sapiens (human): 346007
Entry
346007            CDS       T01001                                 
Symbol
EYS, C6orf178, C6orf179, C6orf180, EGFL10, EGFL11, RP25, SPAM, bA166P24.2, bA307F22.3, bA74E24.1, dJ1018A4.2, dJ22I17.2, dJ303F19.1
Name
(RefSeq) eyes shut homolog
  KO
K19601  protein eyes shut
Organism
hsa  Homo sapiens (human)
Disease
H00527  Retinitis pigmentosa
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04990 Domain-containing proteins not elsewhere classified [BR:hsa04990]
    346007 (EYS)
Domain-containing proteins not elsewhere classified [BR:hsa04990]
 Laminin domain-containing proteins
  Laminin G domain-containing proteins
   346007 (EYS)
SSDB
Motif
Pfam: EGF Laminin_G_2 Laminin_G_1 hEGF Laminin_G_3 Plasmod_Pvs28 EGF_2 EGF_CA
Other DBs
NCBI-GeneID: 346007
NCBI-ProteinID: NP_001278938
OMIM: 612424
HGNC: 21555
Ensembl: ENSG00000188107
UniProt: Q5T1H1
Position
6:complement(63719980..65707226)
AA seq 3165 aa
MTDKSIVILSLMVFHSSFINGKTCRRQLVEEWHPQPSSYVVNWTLTENICLDFYRDCWFL
GVNTKIDTSGNQAVPQICPLQIQLGDILVISSEPSLQFPEINLMNVSETSFVGCVQNTTT
EDQLLFGCRLKGMHTVNSKWLSVGTHYFITVMASGPSPCPLGLRLNVTVKQQFCQESLSS
EFCSGHGKCLSEAWSKTYSCHCQPPFSGKYCQELDACSFKPCKNNGSCINKRENWDEQAY
ECVCHPPFTGKNCSEIIGQCQPHVCFHGNCSNITSNSFICECDEQFSGPFCEVSAKPCVS
LLFWKRGICPNSSSAYTYECPKGSSSQNGETDVSEFSLVPCQNGTDCIKISNDVMCICSP
IFTDLLCKSIQTSCESFPLRNNATCKKCEKDYPCSCISGFTEKNCEKAIDHCKLLSINCL
NEEWCFNIIGRFKYVCIPGCTKNPCWFLKNVYLIHQHLCYCGVTFHGICQDKGPAQFEYV
WQLGFAGSEGEKCQGVIDAYFFLAANCTEDATYVNDPEDNNSSCWFPHEGTKEICANGCS
CLSEEDSQEYRYLCFLRWAGNMYLENTTDDQENECQHEAVCKDEINRPRCSCSLSYIGRL
CVVNVDYCLGNHSISVHGLCLALSHNCNCSGLQRYERNICEIDTEDCKSASCKNGTTSTH
LRGYFFRKCVPGFKGTQCEIDIDECASHPCKNGATCIDQPGNYFCQCVPPFKVVDGFSCL
CNPGYVGIRCEQDIDDCILNACEHNSTCKDLHLSYQCVCLSDWEGNFCEQESNECKMNPC
KNNSTCTDLYKSYRCECTSGWTGQNCSEEINECDSDPCMNGGLCHESTIPGQFVCLCPPL
YTGQFCHQRYNLCDLLHNPCRNNSTCLALVDANQHCICREEFEGKNCEIDVKDCLFLSCQ
DYGDCEDMVNNFRCICRPGFSGSLCEIEINECSSEPCKNNGTCVDLTNRFFCNCEPEYHG
PFCELDVNKCKISPCLDEENCVYRTDGYNCLCAPGYTGINCEINLDECLSEPCLHDGVCI
DGINHYTCDCKSGFFGTHCETNANDCLSNPCLHGRCTELINEYPCSCDADGTSTQCKIKI
NDCTSIPCMNEGFCQKSAHGFTCICPRGYTGAYCEKSIDNCAEPELNSVICLNGGICVDG
PGHTFDCRCLPGFSGQFCEININECSSSPCLHGADCEDHINGYVCKCQPGWSGHHCENEL
ECIPNSCVHELCMENEPGSTCLCTPGFMTCSIGLLCGDEIRRITCLTPIFQRTDPISTQT
YTIPPSETLVSSFPSIKATRIPAIMDTYPVDQGPKQTGIVKHDILPTTGLATLRISTPLE
SYLLQELIVTRELSAKHSLLSSADVSSSRFLNFGIRDPAQIVQDKTSVSHMPIRTSAATL
GFFFPDRRARTPFIMSSLMSDFIFPTQSLLFENCQTVALSATPTTSVIRSIPGADIELNR
QSLLSRGFLLIAASISATPVVSRGAQEDIEEYSADSLISRREHWRLLSPSMSPIFPAKVI
ISKQVTILNSSALHRFSTKAFNPSEYQAITEASSNQRLTNIKSQAADSLRELSQTCATCS
MTEIKSSREFSDQVLHSKQSHFYETFWMNSAILASWYALMGAQTITSGHSFSSATEITPS
VAFTEVPSLFPSKKSAKRTILSSSLEESITLSSNLDVNLCLDKTCLSIVPSQTISSDLMN
SDLTSKMTTDELSVSENILKLLKIRQYGITMGPTEVLNQESLLDMEKSKGSHTLFKLHPS
DSSLDFELNLQIYPDVTLKTYSEITHANDFKNNLPPLTGSVPDFSEVTTNVAFYTVSATP
ALSIQTSSSMSVIRPDWPYFTDYMTSLKKEVKTSSEWSKWELQPSVQYQEFPTASRHLPF
TRSLTLSSLESILAPQRLMISDFSCVRYYGDSYLEFQNVALNPQNNISLEFQTFSSYGLL
LYVKQDSNLVDGFFIQLFIENGTLKYHFYCPGEAKFKSINTTVRVDNGQKYTLLIRQELD
PCNAELTILGRNTQICESINHVLGKPLPKSGSVFIGGFPDLHGKIQMPVPVKNFTGCIEV
IEINNWRSFIPSKAVKNYHINNCRSQGFMLSPTASFVDASDVTQGVDTMWTSVSPSVAAP
SVCQQDVCHNGGTCHAIFLSSGIVSFQCDCPLHFTGRFCEKDAGLFFPSFNGNSYLELPF
LKFVLEKEHNRTVTIYLTIKTNSLNGTILYSNGNNCGKQFLHLFLVEGRPSVKYGCGNSQ
NILTVSANYSINTNAFTPITIRYTTPVGSPGVVCMIEMTADGKPPVQKKDTEISHASQAY
FESMFLGHIPANVQIHKKAGPVYGFRGCILDLQVNNKEFFIIDEARHGKNIENCHVPWCA
HHLCRNNGTCISDNENLFCECPRLYSGKLCQFASCENNPCGNGATCVPKSGTDIVCLCPY
GRSGPLCTDAINITQPRFSGTDAFGYTSFLAYSRISDISFHYEFHLKFQLANNHSALQNN
LIFFTGQKGHGLNGDDFLAVGLLNGSVVYSYNLGSGIASIRSEPLNLSLGVHTVHLGKFF
QEGWLKVDDHKNKSIIAPGRLVGLNVFSQFYVGGYSEYTPDLLPNGADFKNGFQGCIFTL
QVRTEKDGHFRGLGNPEGHPNAGRSVGQCHASPCSLMKCGNGGTCIESGTSVYCNCTTGW
KGSFCTETVSTCDPEHDPPHHCSRGATCISLPHGYTCFCPLGTTGIYCEQALILIVILEK
PKPAERKVKKEALSISDPSFRSNELSWMSFASFHVRKKTHIQLQFQPLAADGILFYAAQH
LKAQSGDFLCISLVNSSVQLRYNLGDRTIILETLQKVTINGSTWHIIKAGRVGAEGYLDL
DGINVTEKASTKMSSLDTNTDFYIGGVSSLNLVNPMAIENEPVGFQGCIRQVIINNQELQ
LTEFGAKGGSNVGDCDGTACGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSVSCLNN
LCLHQSLCIPDQSFSYSCLCTLGWVGRYCENKTSFSTAKFMGNSYIKYIDPNYRMRNLQF
TTISLNFSTTKTEGLIVWMGIAQNEENDFLAIGLHNQTLKIAVNLGERISVPMSYNNGTF
CCNKWHHVVVIQNQTLIKAYINNSLILSEDIDPHKNFVALNYDGICYLGGFEYGRKVNIV
TQEIFKTNFVGKIKDVVFFQEPKNIELIKLEGYNVYDGDEQNEVT
NT seq 9498 nt   +upstreamnt  +downstreamnt
atgactgacaaatcaatcgtcattctgagcctgatggtttttcacagctctttcataaat
ggaaaaacatgtagacggcaattggtggaagaatggcatccacaaccctcatcatatgtg
gtaaattggacactaacagaaaacatctgcttggacttctacagagattgctggtttttg
ggtgtaaacactaaaatagatacttcaggcaatcaagctgttccccagatttgccctttg
caaattcaattaggagatatccttgtaatttcttctgaaccatctcttcaatttccagaa
ataaatttgatgaatgtttctgaaacatctttcgttggctgtgtgcaaaataccacaacg
gaagatcagttactttttggctgcagactaaaaggaatgcacactgttaattctaagtgg
ctgagtgttgggacacattattttatcacagttatggcaagtggtccatcaccttgtcca
ctgggacttcgactaaatgtgacagtgaaacagcagttctgccaggaatctctgagttca
gaattttgctctggtcatggtaaatgtcttagtgaagcttggagcaagacatatagctgc
cattgccagcctccattttctggaaaatactgccaggaacttgatgcatgttcttttaaa
ccatgtaaaaataatggcagttgcattaataaaagagaaaattgggatgagcaagcatat
gaatgtgtctgtcacccaccatttacaggaaagaattgctcagaaataattggccagtgt
caaccacatgtctgtttccatggaaactgcagcaatattacttcaaatagtttcatttgt
gaatgtgatgagcaattttcaggtccattctgtgaggtgtcagcaaaaccttgtgtttct
ctgcttttttggaaaagaggaatttgcccaaatagcagttctgcttatacttatgaatgc
ccaaaaggatcttccagccaaaatggtgaaactgatgtcagtgagttttcattagtacca
tgtcagaatggtactgactgcatcaaaatatcaaatgatgttatgtgcatctgttcacca
atatttacagatttgctttgtaagagcattcaaacatcatgtgagtcatttcctttgagg
aataatgctacatgtaagaaatgtgagaaagattatccttgcagctgtatatcaggattt
actgaaaaaaactgtgagaaagcaattgaccactgtaaactgctcagcatcaactgtctg
aatgaagaatggtgtttcaatataattggaagattcaaatatgtatgcattccagggtgc
acaaaaaatccatgttggtttttgaagaatgtttacctaattcatcaacacctctgctac
tgtggagtcaccttccatggtatttgccaagataaaggtcctgctcaatttgaatatgtg
tggcaattgggatttgcaggatctgaaggcgaaaagtgccaaggggttattgatgcctat
ttctttctggctgcaaactgcactgaagatgcaacctatgtgaacgatcctgaagataat
aattcttcatgttggttcccacatgaaggcacaaaagagatttgtgcaaatggatgcagt
tgtttgagtgaagaagacagtcaggaatatcggtatctatgttttctcagatgggctggc
aacatgtatctggaaaatacaactgatgatcaagaaaatgagtgtcaacatgaagctgtt
tgtaaagatgaaattaatagacccagatgcagctgttctcttagttacattggcagattg
tgtgttgtcaatgttgactattgcttagggaaccacagtatatcagtgcatggcctctgc
ctggccctttcgcacaattgtaactgtagcggtctgcaaagatatgaaaggaacatctgt
gagatagatactgaagactgcaaatctgcgtcctgcaaaaatggaacaactagtacacat
ttaaggggatatttcttccgcaagtgtgtcccaggatttaaaggtacgcaatgtgaaatt
gatatagatgagtgtgcttcacatccctgcaaaaatggagccacctgcattgaccaacct
ggtaattacttctgccagtgtgtgcctccatttaaagtggttgatggcttttcctgctta
tgcaatccaggctatgttgggataagatgtgaacaggacattgatgactgcatcctgaat
gcctgtgagcacaattctacctgcaaagacctgcatctcagctaccagtgtgtgtgccta
tctgattgggaaggaaatttttgtgaacaagaatccaatgagtgtaaaatgaatccttgc
aagaacaattccacctgtactgacctttacaaaagctatcgatgtgagtgtacatctgga
tggactggacagaactgtagtgaagaaataaatgaatgcgactctgatccatgcatgaat
ggaggtctttgtcatgaatctaccatccctggacaatttgtatgtctgtgcccacccctt
tatactggacaattttgccaccaacgctataacctttgtgacctacttcataacccttgc
agaaacaactcaacatgcttagctttggtagacgcaaatcagcattgtatttgtagagaa
gaatttgaaggtaaaaactgtgaaattgatgtgaaagactgcctcttcctttcctgccag
gattatggtgactgtgaagatatggtcaacaatttcaggtgtatttgcagacctgggttt
tctggatctctgtgtgaaattgaaattaatgaatgttcctctgaaccttgcaaaaataat
ggaacatgtgtggatctgacaaacagatttttttgtaattgtgaacctgagtaccatggg
cccttctgtgaacttgatgtaaataaatgtaaaatctcaccttgtctagatgaagaaaat
tgtgtctacaggactgatggatacaactgcctctgtgcccctggttatacaggcatcaac
tgtgaaataaatctagatgaatgcctatcagagccctgtctccatgatggagtttgtatc
gatggcatcaatcattatacctgtgactgcaagagtgggttttttggaacacactgtgaa
acaaacgccaatgattgcctttcaaatccttgtctacatggaaggtgcacagaacttatt
aatgaatatccatgttcatgtgatgcagatgggactagcacacaatgtaagatcaaaatt
aatgactgcacatcaatcccttgtatgaatgaaggcttctgtcagaagtcagcacatgga
tttacttgcatttgcccacgtggatacactggtgcatactgtgaaaaaagcattgataat
tgtgctgagcctgaacttaattcagtcatctgtcttaatggagggatctgtgttgatggg
cctggacatacttttgactgcagatgtcttcctggattttctggtcaattttgtgaaatt
aatataaatgaatgctcttcatcaccatgtctacatggtgcagactgtgaagatcacatc
aatggatatgtttgcaaatgccaaccaggatggtctggacaccactgtgagaatgagctt
gagtgcattcccaactcatgtgttcatgaactctgcatggagaatgaacctggctcgaca
tgtttatgcacacctggatttatgacctgctccattgggcttctttgtggtgatgaaata
aggagaattacctgtttaactcccatctttcaaagaacagatcccatttccacacagaca
tatacaattcccccttctgagactttggtcagcagctttccatctataaaggctactaga
ataccagccataatggacacttacccagttgatcaaggtccaaaacagacaggcattgtc
aagcacgacattctcccaaccactggtttggcaacattaagaattagcacacccttggaa
agctacttactccaagaactgattgtcactagagagctttcagcaaaacacagtcttctt
tcttccgcagatgtttcctcttctcgattcctgaattttggtattcgtgacccagcacaa
attgtccaggacaaaacatcggtatcacatatgcctattcgaacttcagcagccacacta
ggtttcttttttcctgataggagagcaaggaccccatttatcatgtcttccttaatgtca
gattttatttttcctacacaatctttattatttgagaactgtcagactgttgctttatct
gctaccccaacgacttcagtaattagaagcattccaggggctgatattgagctaaacagg
cagtcattactctcccgtggattcctgcttatagctgcctccataagtgcaactccagtt
gtctctaggggggctcaagaggatattgaagaatattcagctgattctttaatttcaaga
agagagcactggagattgctcagcccctcgatgtctcccatttttcctgctaaggtaatt
atatctaaacaggtaaccatcttaaactcatcagctctgcaccggttcagtacaaaagcc
ttcaatcccagtgaatatcaggctattactgaggcttcaagcaaccagagactcacaaac
atcaaatcacaggctgctgattctttaagagaattaagccaaacatgtgcaacatgttct
atgactgaaataaaatcctctcgtgaattctcagatcaagttttgcatagcaaacagtcc
cacttttatgagacattctggatgaactcagcgatattagccagctggtatgcactaatg
ggagctcaaactatcacttctgggcattcattttcttctgctactgaaataacaccatca
gtggcattcacagaagtgccatctttatttccttctaaaaagagtgcaaaaagaacaatt
ttatcctcatccttggaagaatccattaccctatcaagtaatttggatgttaatttatgt
ttggataagacttgtttatccattgtcccttcacaaactatctcttcagacttgatgaat
tctgatttgacttcaaaaatgactactgatgaactgtcagtatcagaaaacattttaaaa
ctattgaaaataagacaatatggcataactatgggacccactgaggtactaaatcaagag
agcttattggacatggaaaaaagtaaaggatctcatacactgttcaaacttcacccaagt
gatagttctctggattttgagttaaacttacaaatttatccggatgttactttaaagaca
tattcagaaattacacatgcaaatgacttcaaaaataatctgccaccattgacaggctca
gtgcctgatttttcagaagtcaccaccaatgttgcattttatacagtttcagcaactcca
gcactttcaatacagacgtcttcctccatgtctgtaattaggccagattggccatatttt
acagattatatgacctctcttaaaaaagaggtcaagacttcttcagaatggtccaaatgg
gaacttcagcctagtgtgcaatatcaggaatttcccactgcaagccggcatcttcccttc
actagatctcttactttgtcttcactggaatccattctggcacctcaacggctgatgatt
tctgatttcagttgtgttcgttattatggagattcttatctagaatttcagaatgtggct
ttaaatccacaaaataacatctccctagaatttcagaccttcagctcctatggacttctg
ctgtatgtcaagcaagactcaaatttagtagatggattttttattcaattgtttattgaa
aatggtactttaaagtaccacttttactgtcctggtgaagcaaaatttaaaagcattaat
actactgttagagtggacaacgggcaaaagtatacactgcttatcaggcaagaattggat
ccatgtaacgctgagctgactattttagggaggaatacacaaatatgcgaatctatcaat
catgtactcggaaaacccctgccaaaatcaggatctgtcttcattggtggatttccagac
cttcatgggaaaatccagatgcctgtaccagtcaagaattttactggctgcatagaagtt
atagaaataaataactggagatctttcattccatccaaggcagtgaaaaactatcacatt
aacaattgcagatcccagggatttatgctgtctccaacagcctcctttgttgatgcttct
gatgtgacacaaggggttgataccatgtggacttctgtcagcccctctgttgcagcaccc
tctgtgtgccagcaggatgtatgccacaatggaggcacatgccatgccatcttcctctcc
agtggcatagtgtcattccaatgtgactgtccactacatttcactggccgcttctgtgaa
aaagatgcaggtttattctttccatctttcaatgggaattcctatttagaactgcccttt
ttgaagtttgtcctggagaaggaacataacagaactgttaccatctacttgactataaaa
acaaacagtttaaatggaactattctttacagtaatgggaataattgtggaaagcagttt
cttcatttatttcttgtggaaggaaggccatcagttaaatatgggtgtggaaattctcaa
aatattttgactgtttctgctaattacagcattaacacaaatgcattcacccctatcaca
atacgctacacaacgcctgttggcagccctggagttgtttgtatgattgaaatgactgca
gatggaaaacctccagtacagaagaaagacacagagatttcccatgcctctcaggcatat
tttgaatcaatgttccttggccatattcctgcaaatgttcaaattcataagaaagcaggt
cctgtttatgggttcaggggctgcattctagaccttcaagtaaacaacaaagaattcttc
atcatcgatgaagcacgacatggaaagaatattgagaactgccacgtcccttggtgtgct
catcatctgtgccgcaacaatggcacctgcatcagtgataatgaaaatctgttttgtgag
tgtccaaggctgtattcaggcaagctgtgccagtttgcaagttgtgaaaacaacccatgt
ggaaatggtgccacctgtgttccaaaatccggaacagatattgtctgcctctgcccatat
gggaggtctggacccctctgcactgatgctattaatattactcagccaaggttcagtggc
acagatgcctttggatacacctcattcctggcttattcacggatctcagacatcagcttc
cattatgaattccacctgaagtttcagctggcaaacaaccactcagcactgcaaaataac
ttgatattttttactggacagaaaggccatgggttgaatggcgatgacttcctggctgtg
ggcctgctcaatggcagtgtggtttatagttataacctggggtctggcatagcaagcatc
aggagcgagcccctcaatctgagccttggagtccacactgttcatctgggcaagttcttc
caagagggctggctgaaggtagatgatcataaaaataaatccattatcgccccaggaaga
ctggttggtctcaatgtcttcagtcagttttatgtaggtggctacagtgaatacactcca
gatctcttaccaaatggagcagattttaaaaatggttttcaaggctgtattttcactctt
caagttcgcactgagaaggatggccatttcagaggactgggaaatcctgagggccaccca
aatgctggacgcagtgttggccagtgtcatgcttctccctgcagtttaatgaaatgtggc
aatggtgggacatgcatagagagtggaactagtgtttactgcaattgtaccactgggtgg
aaaggatcattctgcacagagacagtttctacctgtgatcctgaacatgaccctccacac
cactgtagcagaggagcaacctgcatttcattacctcatggatacacctgtttctgtcct
ctaggaaccactggaatctactgtgaacaagcacttatcctcattgtgatcttggaaaag
ccaaaaccagcagaacggaaagtgaagaaggaggctttatccataagtgatccatctttc
agaagcaatgagttatcctggatgtcttttgcttcctttcatgttcgaaaaaagacacat
attcaattgcagtttcagcctctcgctgcagatggtatcctattttatgctgcacaacac
ttaaaagcccaatcaggtgattttttatgcatctctttagtaaatagttccgttcaactt
cgctacaaccttggcgacagaactatcattctagaaactctccaaaaagtaactataaac
ggaagtacttggcatataataaaagcaggaagagttggtgcagaaggctacctggatcta
gatgggataaatgtaacagaaaaggcctccactaaaatgagttctctggacacaaataca
gacttctatattggaggagtatcttctttaaatcttgtaaatcccatggcaatagaaaat
gaacctgtaggttttcaaggctgtatccgacaagttatcataaataatcaagaattacaa
ttaactgaatttggagcaaaaggtggctcaaatgtaggtgactgtgatgggacagcctgt
gggtacaacacatgcagaaatggaggtgaatgtacagtaaatggcacaactttttcttgc
agatgtttgccagattgggctggaaatacatgtaaccagtctgtgtcctgtttgaataat
ctttgcctccaccaatctttatgtatacctgaccaatcattttcttacagttgcctgtgt
actttgggttgggtgggaaggtattgtgaaaacaaaacttcattttcaactgcaaaattt
atgggtaattcttacattaaatacattgatccaaattatagaatgagaaacctccagttc
actactatatccttaaatttcagtaccactaaaacagaaggtctaattgtatggatggga
atagctcaaaatgaagaaaatgattttctggcaattggtctccataatcagaccttgaaa
atagcagttaacttgggagaaagaatctctgtgcctatgagctataacaatggcacattc
tgttgtaataaatggcaccatgtagttgtaattcaaaatcagactcttatcaaggcctac
ataaataacagtctaattctttccgaggatattgatccacataaaaactttgtggctcta
aactatgatggcatttgttatctagggggctttgaatatggtagaaaggtaaatatcgtt
actcaagagatttttaaaaccaattttgttggcaaaattaaagatgttgtattttttcag
gaaccaaaaaacattgaactaattaaattagaaggatacaatgtttatgatggagatgaa
caaaatgaggttacataa

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Disease (3)   
   KEGG DISEASE (1)   
   OMIM (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (143)   
   KEGG ORTHOLOGY (1)   
   RefGene (134)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (3)   
   OC (1)   
Protein sequence (6)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (4)   
DNA sequence (24)   
   RefSeq(nuc) (4)   
   GenBank (10)   
   EMBL (10)   
Protein domain (8)   
   Pfam (8)   
All databases (187)   

Download RDF
DBGET integrated database retrieval system