KEGG   Homo sapiens (human): 4647
Entry
4647              CDS       T01001                                 
Symbol
MYO7A, DFNA11, DFNB2, MYOVIIA, MYU7A, NSRD2, USH1B
Name
(RefSeq) myosin VIIA
  KO
K10359  myosin VIIa
Organism
hsa  Homo sapiens (human)
Pathway
hsa04814  Motor proteins
Disease
H00604  Deafness, autosomal dominant
H00605  Deafness, autosomal recessive
H00779  Usher syndrome
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09140 Cellular Processes
  09142 Cell motility
   04814 Motor proteins
    4647 (MYO7A)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:hsa04131]
    4647 (MYO7A)
  09183 Protein families: signaling and cellular processes
   03037 Cilium and associated proteins [BR:hsa03037]
    4647 (MYO7A)
   04812 Cytoskeleton proteins [BR:hsa04812]
    4647 (MYO7A)
Membrane trafficking [BR:hsa04131]
 Others
  Actin-binding proteins
   Myosins
    4647 (MYO7A)
Cilium and associated proteins [BR:hsa03037]
 Primary cilia and associated proteins
  USH complex and associated proteins
   4647 (MYO7A)
Cytoskeleton proteins [BR:hsa04812]
 Eukaryotic cytoskeleton proteins
  Actin filaments / Microfilaments
   Actin-binding proteins
    Myosins
     4647 (MYO7A)
SSDB
Motif
Pfam: Myosin_head MyTH4 FERM_M IQ FERM_N SH3_9 AAA_22 SH3_1 nSTAND3 PID ABC_tran AAA_19 AAA_16
Other DBs
NCBI-GeneID: 4647
NCBI-ProteinID: NP_000251
OMIM: 276903
HGNC: 7606
Ensembl: ENSG00000137474
UniProt: Q13402
Structure
Position
11:77128246..77215241
AA seq 2215 aa
MVILQQGDHVWMDLRLGQEFDVPIGAVVKLCDSGQVQVVDDEDNEHWISPQNATHIKPMH
PTSVHGVEDMIRLGDLNEAGILRNLLIRYRDHLIYTYTGSILVAVNPYQLLSIYSPEHIR
QYTNKKIGEMPPHIFAIADNCYFNMKRNSRDQCCIISGESGAGKTESTKLILQFLAAISG
QHSWIEQQVLEATPILEAFGNAKTIRNDNSSRFGKYIDIHFNKRGAIEGAKIEQYLLEKS
RVCRQALDERNYHVFYCMLEGMSEDQKKKLGLGQASDYNYLAMGNCITCEGRVDSQEYAN
IRSAMKVLMFTDTENWEISKLLAAILHLGNLQYEARTFENLDACEVLFSPSLATAASLLE
VNPPDLMSCLTSRTLITRGETVSTPLSREQALDVRDAFVKGIYGRLFVWIVDKINAAIYK
PPSQDVKNSRRSIGLLDIFGFENFAVNSFEQLCINFANEHLQQFFVRHVFKLEQEEYDLE
SIDWLHIEFTDNQDALDMIANKPMNIISLIDEESKFPKGTDTTMLHKLNSQHKLNANYIP
PKNNHETQFGINHFAGIVYYETQGFLEKNRDTLHGDIIQLVHSSRNKFIKQIFQADVAMG
AETRKRSPTLSSQFKRSLELLMRTLGACQPFFVRCIKPNEFKKPMLFDRHLCVRQLRYSG
MMETIRIRRAGYPIRYSFVEFVERYRVLLPGVKPAYKQGDLRGTCQRMAEAVLGTHDDWQ
IGKTKIFLKDHHDMLLEVERDKAITDRVILLQKVIRGFKDRSNFLKLKNAATLIQRHWRG
HNCRKNYGLMRLGFLRLQALHRSRKLHQQYRLARQRIIQFQARCRAYLVRKAFRHRLWAV
LTVQAYARGMIARRLHQRLRAEYLWRLEAEKMRLAEEEKLRKEMSAKKAKEEAERKHQER
LAQLAREDAERELKEKEAARRKKELLEQMERARHEPVNHSDMVDKMFGFLGTSGGLPGQE
GQAPSGFEDLERGRREMVEEDLDAALPLPDEDEEDLSEYKFAKFAATYFQGTTTHSYTRR
PLKQPLLYHDDEGDQLAALAVWITILRFMGDLPEPKYHTAMSDGSEKIPVMTKIYETLGK
KTYKRELQALQGEGEAQLPEGQKKSSVRHKLVHLTLKKKSKLTEEVTKRLHDGESTVQGN
SMLEDRPTSNLEKLHFIIGNGILRPALRDEIYCQISKQLTHNPSKSSYARGWILVSLCVG
CFAPSEKFVKYLRNFIHGGPPGYAPYCEERLRRTFVNGTRTQPPSWLELQATKSKKPIML
PVTFMDGTTKTLLTDSATTAKELCNALADKISLKDRFGFSLYIALFDKVSSLGSGSDHVM
DAISQCEQYAKEQGAQERNAPWRLFFRKEVFTPWHSPSEDNVATNLIYQQVVRGVKFGEY
RCEKEDDLAELASQQYFVDYGSEMILERLLNLVPTYIPDREITPLKTLEKWAQLAIAAHK
KGIYAQRRTDAQKVKEDVVSYARFKWPLLFSRFYEAYKFSGPSLPKNDVIVAVNWTGVYF
VDEQEQVLLELSFPEIMAVSSSRECRVWLSLGCSDLGCAAPHSGWAGLTPAGPCSPCWSC
RGAKTTAPSFTLATIKGDEYTFTSSNAEDIRDLVVTFLEGLRKRSKYVVALQDNPNPAGE
ESGFLSFAKGDLIILDHDTGEQVMNSGWANGINERTKQRGDFPTDSVYVMPTVTMPPREI
VALVTMTPDQRQDVVRLLQLRTAEPEVRAKPYTLEEFSYDYFRPPPKHTLSRVMVSKARG
KDRLWSHTREPLKQALLKKLLGSEELSQEACLAFIAVLKYMGDYPSKRTRSVNELTDQIF
EGPLKAEPLKDEAYVQILKQLTDNHIRYSEERGWELLWLCTGLFPPSNILLPHVQRFLQS
RKHCPLAIDCLQRLQKALRNGSRKYPPHLVEVEAIQHKTTQIFHKVYFPDDTDEAFEVES
STKAKDFCQNIATRLLLKSSEGFSLFVKIADKVLSVPENDFFFDFVRHLTDWIKKARPIK
DGIVPSLTYQVFFMKKLWTTTVPGKDPMADSIFHYYQELPKYLRGYHKCTREEVLQLGAL
IYRVKFEEDKSYFPSIPKLLRELVPQDLIRQVSPDDWKRSIVAYFNKHAGKSKEEAKLAF
LKLIFKWPTFGSAFFEVKQTTEPNFPEILLIAINKYGVSLIDPKTKDILTTHPFTKISNW
SSGNTYFHITIGNLVRGSKLLCETSLGYKMDDLLTSYISQMLTAMSKQRGSRSGK
NT seq 6648 nt   +upstreamnt  +downstreamnt
atggtgattcttcagcagggggaccatgtgtggatggacctgagattggggcaggagttc
gacgtgcccatcggggcggtggtgaagctctgcgactctgggcaggtccaggtggtggat
gatgaagacaatgaacactggatctctccgcagaacgcaacgcacatcaagcctatgcac
cccacgtcggtccacggcgtggaggacatgatccgcctgggggacctcaacgaggcgggc
atcttgcgcaacctgcttatccgctaccgggaccacctcatctacacgtatacgggctcc
atcctggtggctgtgaacccctaccagctgctctccatctactcgccagagcacatccgc
cagtataccaacaagaagattggggagatgcccccccacatctttgccattgctgacaac
tgctacttcaacatgaaacgcaacagccgagaccagtgctgcatcatcagtggggaatct
ggggccgggaagacggagagcacaaagctgatcctgcagttcctggcagccatcagtggg
cagcactcgtggattgagcagcaggtcttggaggccacccccattctggaagcatttggg
aatgccaagaccatccgcaatgacaactcaagccgtttcggaaagtacatcgacatccac
ttcaacaagcggggcgccatcgagggcgcgaagattgagcagtacctgctggaaaagtca
cgtgtctgtcgccaggccctggatgaaaggaactaccacgtgttctactgcatgctggag
ggtatgagtgaggatcagaagaagaagctgggcttgggccaggcctctgactacaactac
ttggccatgggtaactgcataacctgtgagggccgggtggacagccaggagtacgccaac
atccgctccgccatgaaggtgctcatgttcactgacaccgagaactgggagatctcgaag
ctcctggctgccatcctgcacctgggcaacctgcagtatgaggcacgcacatttgaaaac
ctggatgcctgtgaggttctcttctccccatcgctggccacagctgcatccctgcttgag
gtgaaccccccagacctgatgagctgcctgactagccgcaccctcatcacccgcggggag
acggtgtccaccccactgagcagggaacaggcactggacgtgcgcgacgccttcgtaaag
gggatctacgggcggctgttcgtgtggattgtggacaagatcaacgcagcaatttacaag
cctccctcccaggatgtgaagaactctcgcaggtccatcggcctcctggacatctttggg
tttgagaactttgctgtgaacagctttgagcagctctgcatcaacttcgccaatgagcac
ctgcagcagttctttgtgcggcacgtgttcaagctggagcaggaggaatatgacctggag
agcattgactggctgcacatcgagttcactgacaaccaggatgccctggacatgattgcc
aacaagcccatgaacatcatctccctcatcgatgaggagagcaagttccccaagggcaca
gacaccaccatgttacacaagctgaactcccagcacaagctcaacgccaactacatcccc
cccaagaacaaccatgagacccagtttggcatcaaccattttgcaggcatcgtctactat
gagacccaaggcttcctggagaagaaccgagacaccctgcatggggacattatccagctg
gtccactcctccaggaacaagttcatcaagcagatcttccaggccgatgtcgccatgggc
gccgagaccaggaagcgctcgcccacacttagcagccagttcaagcggtcactggagctg
ctgatgcgcacgctgggtgcctgccagcccttctttgtgcgatgcatcaagcccaatgag
ttcaagaagcccatgctgttcgaccggcacctgtgcgtgcgccagctgcggtactcagga
atgatggagaccatccgaatccgccgagctggctaccccatccgctacagcttcgtagag
tttgtggagcggtaccgtgtgctgctgccaggtgtgaagccggcctacaagcagggcgac
ctccgcgggacttgccagcgcatggctgaggctgtgctgggcacccacgatgactggcag
ataggcaaaaccaagatctttctgaaggaccaccatgacatgctgctggaagtggagcgg
gacaaagccatcaccgacagagtcatcctccttcagaaagtcatccggggattcaaagac
aggtctaactttctgaagctgaagaacgctgccacactgatccagaggcactggcggggt
cacaactgtaggaagaactacgggctgatgcgtctgggcttcctgcggctgcaggccctg
caccgctcccggaagctgcaccagcagtaccgcctggcccgccagcgcatcatccagttc
caggcccgctgccgcgcctatctggtgcgcaaggccttccgccaccgcctctgggctgtg
ctcaccgtgcaggcctatgcccggggcatgatcgcccgcaggctgcaccaacgcctcagg
gctgagtatctgtggcgcctcgaggctgagaaaatgcggctggcggaggaagagaagctt
cggaaggagatgagcgccaagaaggccaaggaggaggccgagcgcaagcatcaggagcgc
ctggcccagctggctcgtgaggacgctgagcgggagctgaaggagaaggaggccgctcgg
cggaagaaggagctcctggagcagatggaaagggcccgccatgagcctgtcaatcactca
gacatggtggacaagatgtttggcttcctggggacttcaggtggcctgccaggccaggag
ggccaggcacctagtggctttgaggacctggagcgagggcggagggagatggtggaggag
gacctggatgcagccctgcccctgcctgacgaggatgaggaggacctctctgagtataaa
tttgccaagttcgcggccacctacttccaggggacaaccacgcactcctacacccggcgg
ccactcaaacagccactgctctaccatgacgacgagggtgaccagctggcagccctggcg
gtctggatcaccatcctccgcttcatgggggacctccctgagcccaagtaccacacagcc
atgagtgatggcagtgagaagatccctgtgatgaccaagatttatgagaccctgggcaag
aagacgtacaagagggagctgcaggccctgcagggcgagggcgaggcccagctccccgag
ggccagaagaagagcagtgtgaggcacaagctggtgcatttgactctgaaaaagaagtcc
aagctcacagaggaggtgaccaagaggctgcatgacggggagtccacagtgcagggcaac
agcatgctggaggaccggcccacctccaacctggagaagctgcacttcatcatcggcaat
ggcatcctgcggccagcactccgggacgagatctactgccagatcagcaagcagctgacc
cacaacccctccaagagcagctatgcccggggctggattctcgtgtctctctgcgtgggc
tgtttcgccccctccgagaagtttgtcaagtacctgcggaacttcatccacgggggcccg
cccggctacgccccgtactgtgaggagcgcctgagaaggacctttgtcaatgggacacgg
acacagccgcccagctggctggagctgcaggccaccaagtccaagaagccaatcatgttg
cccgtgacattcatggatgggaccaccaagaccctgctgacggactcggcaaccacggcc
aaggagctctgcaacgcgctggccgacaagatctctctcaaggaccggttcgggttctcc
ctctacattgccctgtttgacaaggtgtcctccctgggcagcggcagtgaccacgtcatg
gacgccatctcccagtgcgagcagtacgccaaggagcagggcgcccaggagcgcaacgcc
ccctggaggctcttcttccgcaaagaggtcttcacgccctggcacagcccctccgaggac
aacgtggccaccaacctcatctaccagcaggtggtgcgaggagtcaagtttggggagtac
aggtgtgagaaggaggacgacctggctgagctggcctcccagcagtactttgtagactat
ggctctgagatgatcctggagcgcctcctgaacctcgtgcccacctacatccccgaccgc
gagatcacgcccctgaagacgctggagaagtgggcccagctggccatcgccgcccacaag
aaggggatttatgcccagaggagaactgatgcccagaaggtcaaagaggatgtggtcagt
tatgcccgcttcaagtggcccttgctcttctccaggttttatgaagcctacaaattctca
ggccccagtctccccaagaacgacgtcatcgtggccgtcaactggacgggtgtgtacttt
gtggatgagcaggagcaggtacttctggagctgtccttcccagagatcatggccgtgtcc
agcagcagggagtgccgtgtctggctctcactgggctgctctgatcttggctgtgctgcg
cctcactcaggctgggcaggactgaccccggcggggccctgttctccgtgttggtcctgc
aggggagcgaaaacgacggcccccagcttcacgctggccaccatcaagggggacgaatac
accttcacctccagcaatgctgaggacattcgtgacctggtggtcaccttcctagagggg
ctccggaagagatctaagtatgttgtggccctgcaggataaccccaaccccgcaggcgag
gagtcaggcttcctcagctttgccaagggagacctcatcatcctggaccatgacacgggc
gagcaggtcatgaactcgggctgggccaacggcatcaatgagaggaccaagcagcgtggg
gacttccccaccgacagtgtgtacgtcatgcccactgtcaccatgccaccgcgggagatt
gtggccctggtcaccatgactcccgatcagaggcaggacgttgtccggctcttgcagctg
cgaacggcggagcccgaggtgcgtgccaagccctacacgctggaggagttttcctatgac
tacttcaggcccccacccaagcacacgctgagccgtgtcatggtgtccaaggcccgaggc
aaggaccggctgtggagccacacgcgggaaccgctcaagcaggcgctgctcaagaagctc
ctgggcagtgaggagctctcgcaggaggcctgcctggccttcattgctgtgctcaagtac
atgggcgactacccgtccaagaggacacgctccgtcaacgagctcaccgaccagatcttt
gagggtcccctgaaagccgagcccctgaaggacgaggcatatgtgcagatcctgaagcag
ctgaccgacaaccacatcaggtacagcgaggagcggggttgggagctgctctggctgtgc
acgggccttttcccacccagcaacatcctcctgccccacgtgcagcgcttcctgcagtcc
cgaaagcactgcccactcgccatcgactgcctgcaacggctccagaaagccctgagaaac
gggtcccggaagtaccctccgcacctggtggaggtggaggccatccagcacaagaccacc
cagattttccacaaagtctacttccctgatgacactgacgaggccttcgaagtggagtcc
agcaccaaggccaaggacttctgccagaacatcgccaccaggctgctcctcaagtcctca
gagggattcagcctctttgtcaaaattgcagacaaggtcctcagcgttcctgagaatgac
ttcttctttgactttgttcgacacttgacagactggataaagaaagctcggcccatcaag
gacggaattgtgccctcactcacctaccaggtgttcttcatgaagaagctgtggaccacc
acggtgccagggaaggatcccatggccgattccatcttccactattaccaggagttgccc
aagtatctccgaggctaccacaagtgcacgcgggaggaggtgctgcagctgggggcgctg
atctacagggtcaagttcgaggaggacaagtcctacttccccagcatccccaagctgctg
cgggagctggtgccccaggaccttatccggcaggtctcacctgatgactggaagcggtcc
atcgtcgcctacttcaacaagcacgcagggaagtccaaggaggaggccaagctggccttc
ctgaagctcatcttcaagtggcccacctttggctcagccttcttcgaggtgaagcaaact
acggagccaaacttccctgagatcctcctaattgccatcaacaagtatggggtcagcctc
atcgatcccaaaacgaaggatatcctcaccactcatcccttcaccaagatctccaactgg
agcagcggcaacacctacttccacatcaccattgggaacttggtgcgcgggagcaaactg
ctctgcgagacgtcactgggctacaagatggatgacctcctgacttcctacattagccag
atgctcacagccatgagcaaacagcggggctccaggagcggcaagtga

  All links  
Ontology (4)   
   KEGG BRITE (4)   
Pathway (1)   
   KEGG PATHWAY (1)   
Disease (7)   
   KEGG DISEASE (3)   
   OMIM (4)   
Genome (1)   
   KEGG GENOME (1)   
Gene (24)   
   KEGG ORTHOLOGY (1)   
   RefGene (18)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (43)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (41)   
DNA sequence (68)   
   RefSeq(nuc) (46)   
   GenBank (11)   
   EMBL (11)   
3D Structure (1)   
   PDB (1)   
Protein domain (13)   
   Pfam (13)   
All databases (162)   

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