KEGG H.sapiens: 5337

Homo sapiens (human): 5337

Entry

5337 CDS H.sapiens

Gene name PLD1

Definition phospholipase D1, phosphatidylcholine-specific (EC:3.1.4.4)

Orthology K01115 phospholipase D [EC:3.1.4.4]

Pathway hsa00564 Glycerophospholipid metabolism
hsa00565 Ether lipid metabolism
hsa01100 Metabolic pathways
hsa04144 Endocytosis
hsa04666 Fc gamma R-mediated phagocytosis
hsa04912 GnRH signaling pathway
hsa05200 Pathways in cancer
hsa05212 Pancreatic cancer

Class Metabolism; Lipid Metabolism; Glycerophospholipid metabolism
[PATH:hsa00564]
Metabolism; Lipid Metabolism; Ether lipid metabolism [PATH:hsa00565]
Cellular Processes; Transport and Catabolism; Endocytosis
[PATH:hsa04144]
Organismal Systems; Immune System; Fc gamma R-mediated phagocytosis
[PATH:hsa04666]
Organismal Systems; Endocrine System; GnRH signaling pathway
[PATH:hsa04912]
Human Diseases; Cancers; Pathways in cancer [PATH:hsa05200]

SSDB

Motif Pfam: PX PLDc PH
PROSITE: PX PLD

Other DBs NCBI-GI: 194272176
NCBI-GeneID: 5337
OMIM: 602382
HGNC: 9067
HPRD: 03855
Ensembl: ENSG00000075651
UniProt: Q13393 Q59EA4

Position 3q26

AA seq 1036 aa
MSLKNEPRVNTSALQKIAADMSNIIENLDTRELHFEGEEVDYDVSPSDPKIQEVYIPFSA
IYNTQGFKEPNIQTYLSGCPIKAQVLEVERFTSTTRVPSINLYTIELTHGEFKWQVKRKF
KHFQEFHRELLKYKAFIRIPIPTRRHTFRRQNVREEPREMPSLPRSSENMIREEQFLGRR
KQLEDYLTKILKMPMYRNYHATTEFLDISQLSFIHDLGPKGIEGMIMKRSGGHRIPGLNC
CGQGRACYRWSKRWLIVKDSFLLYMKPDSGAIAFVLLVDKEFKIKVGKKETETKYGIRID
NLSRTLILKCNSYRHARWWGGAIEEFIQKHGTNFLKDHRFGSYAAIQENALAKWYVNAKG
YFEDVANAMEEANEEIFITDWWLSPEIFLKRPVVEGNRWRLDCILKRKAQQGVRIFIMLY
KEVELALGINSEYTKRTLMRLHPNIKVMRHPDHVSSTVYLWAHHEKLVIIDQSVAFVGGI
DLAYGRWDDNEHRLTDVGSVKRVTSGPSLGSLPPAAMESMESLRLKDKNEPVQNLPIQKS
IDDVDSKLKGIGKPRKFSKFSLYKQLHRHHLHDADSISSIDSTSNTGSIRSLQTGVGELH
GETRFWHGKDYCNFVFKDWVQLDKPFADFIDRYSTPRMPWHDIASAVHGKAARDVARHFI
QRWNFTKIMKSKYRSLSYPFLLPKSQTTAHELRYQVPGSVHANVQLLRSAADWSAGIKYH
EESIHAAYVHVIENSRHYIYIENQFFISCADDKVVFNKIGDAIAQRILKAHRENQKYRVY
VVIPLLPGFEGDISTGGGNALQAIMHFNYRTMCRGENSILGQLKAELGNQWINYISFCGL
RTHAELEGNLVTELIYVHSKLLIADDNTVIIGSANINDRSMLGKRDSEMAVIVQDTETVP
SVMDGKEYQAGRFARGLRLQCFRVVLGYLDDPSEDIQDPVSDKFFKEVWVSTAARNATIY
DKVFRCLPNDEVHNLIQLRDFINKPVLAKEDPIRAEEELKKIRGFLVQFPFYFLSEESLL
PSVGTKEAIVPMEVWT

NT seq 3111 nt +upstreamnt +downstreamnt
atgtcactgaaaaacgagccacgggtaaatacctctgcactgcagaaaattgctgctgac
atgagtaatatcatagaaaatctggacacgcgggaactccactttgagggagaggaggta
gactacgacgtgtctcccagcgatcccaagatacaagaagtgtatatccctttctctgct
atttataacactcaaggatttaaggagcctaatatacagacgtatctctccggctgtcca
ataaaagcacaagttctggaagtggaacgcttcacatctacaacaagggtaccaagtatt
aatctttacactattgaattaacacatggggaatttaaatggcaagttaagaggaaattc
aagcattttcaagaatttcacagagagctgctcaagtacaaagcctttatccgcatcccc
attcccactagaagacacacgtttaggaggcaaaacgtcagagaggagcctcgagagatg
cccagtttgccccgttcatctgaaaacatgataagagaagaacaattccttggtagaaga
aaacaactggaagattacttgacaaagatactaaaaatgcccatgtatagaaactatcat
gccacaacagagtttcttgatataagccagctgtctttcatccatgatttgggaccaaag
ggcatagaaggtatgataatgaaaagatctggaggacacagaataccaggcttgaattgc
tgtggtcagggaagagcctgctacagatggtcaaaaagatggttaatagtgaaagattcc
tttttattgtatatgaaaccagacagcggtgccattgccttcgtcctgctggtagacaaa
gaattcaaaattaaggtggggaagaaggagacagaaacgaaatatggaatccgaattgat
aatctttcaaggacacttattttaaaatgcaacagctatagacatgctcggtggtgggga
ggggctatagaagaattcatccagaaacatggcaccaactttctcaaagatcatcgattt
gggtcatatgctgctatccaagagaatgctttagctaaatggtatgttaatgccaaagga
tattttgaagatgtggcaaatgcaatggaagaggcaaatgaagagatttttatcacagac
tggtggctgagtccagaaatcttcctgaaacgcccagtggttgagggaaatcgttggagg
ttggactgcattcttaaacgaaaagcacaacaaggagtgaggatcttcataatgctctac
aaagaggtggaactcgctcttggcatcaatagtgaatacaccaagaggactttgatgcgt
ctacatcccaacataaaggtgatgagacacccggatcatgtgtcatccaccgtctatttg
tgggctcaccatgagaagcttgtcatcattgaccaatcggtggcctttgtgggagggatt
gacctggcctatggaaggtgggacgacaatgagcacagactcacagacgtgggcagtgtg
aagcgggtcacttcaggaccgtctctgggttccctcccacctgccgcaatggagtctatg
gaatccttaagactcaaagataaaaatgagcctgttcaaaacctacccatccagaagagt
attgatgatgtggattcaaaactgaaaggaataggaaagccaagaaagttctccaaattt
agtctctacaagcagctccacaggcaccacctgcacgacgcagatagcatcagcagcatt
gacagcacctccaataccgggtccatccgtagtttacagacaggtgtgggagagctgcat
ggggaaaccagattctggcatggaaaggactactgcaatttcgtcttcaaagactgggtt
caacttgataaaccttttgctgatttcattgacaggtactccacgccccggatgccctgg
catgacattgcctctgcagtccacgggaaggcggctcgtgatgtggcacgtcacttcatc
cagcgctggaacttcacaaaaattatgaaatcaaaatatcggtccctttcttatcctttt
ctgcttccaaagtctcaaacaacagcccatgagttgagatatcaagtgcctgggtctgtc
catgctaacgtacagttgctccgctctgctgctgattggtctgctggtataaagtaccat
gaagagtccatccacgccgcttacgtccatgtgatagagaacagcaggcactatatctat
atcgaaaaccagtttttcataagctgtgctgatgacaaagttgtgttcaacaagataggc
gatgccattgcccagaggatcctgaaagctcacagggaaaaccagaaataccgggtatat
gtcgtgataccacttctgccagggttcgaaggagacatttcaaccggcggaggaaatgct
ctacaggcaatcatgcacttcaactacagaaccatgtgcagaggagaaaattccatcctt
ggacagttaaaagcagagcttggtaatcagtggataaattacatatcattctgtggtctt
agaacacatgcagagctcgaaggaaacctagtaactgagcttatctatgtccacagcaag
ttgttaattgctgatgataacactgttattattggctctgccaacataaatgaccgcagc
atgctgggaaagcgtgacagtgaaatggctgtcattgtgcaagatacagagactgttcct
tcagtaatggatggaaaagagtaccaagctggccggtttgcccgaggacttcggctacag
tgctttagggttgtccttggctatcttgatgacccaagtgaggacattcaggatccagtg
agtgacaaattcttcaaggaggtgtgggtttcaacagcagctcgaaatgctacaatttat
gacaaggttttccggtgccttcccaatgatgaagtacacaatttaattcagctgagagac
tttataaacaagcccgtattagctaaggaagatcccattcgagctgaggaggaactgaag
aagatccgtggatttttggtgcaattccccttttatttcttgtctgaagaaagcctactg
ccttctgttgggaccaaagaggccatagtgcccatggaggtttggacttaa

All links

Ontology (1)   
   KEGG BRITE (1)   
Pathway (8)   
   KEGG PATHWAY (8)   
Disease (1)   
   OMIM (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (8)   
   KEGG ORTHOLOGY (1)   
   NCBI-Gene (1)   
   NCBI-GI (2)   
   UNIGENE (1)   
   HGNC (1)   
   HPRD (1)   
   ENSEMBL-HSA (1)   
Protein sequence (14)   
   UniProt (2)   
   RefSeq(pep) (2)   
   IPI (10)   
DNA sequence (8)   
   RefSeq(nuc) (2)   
   GenBank (3)   
   EMBL (3)   
Protein domain (5)   
   Pfam (3)   
   PROSITE (2)   
All databases (47)

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