KEGG T01001: 10060

Homo sapiens (human): 10060

Entry

10060 CDS T01001

Gene name

ABCC9, ABC37, ATFB12, CANTU, CMD1O, SUR2

Definition

ATP-binding cassette, sub-family C (CFTR/MRP), member 9

Orthology

K05033

ATP-binding cassette subfamily C (CFTR/MRP) member 9

Organism

hsa Homo sapiens (human)

Pathway

hsa02010

ABC transporters

Disease

H00294	Dilated cardiomyopathy (DCM)
H00731	Atrial fibrillation

Drug target

Nicorandil:

D01810

Pinacidil:

D05482

Other:

D02385

Class

Environmental Information Processing; Membrane transport; ABC transporters [PATH:hsa02010]

SSDB

Motif

Pfam:

ABC_membrane ABC_tran AAA_21 AAA_25 SMC_N AAA_29 DUF258 Miro ABC_ATPase Zeta_toxin AAA_16 AAA_10 Arch_ATPase FAM177

Other DBs

NCBI-GI:

110832835

NCBI-GeneID:

10060

OMIM:

601439

HGNC:

HPRD:

Ensembl:

Vega:

UniProt:

Position

12p12.1

AA seq 1549 aa
MSLSFCGNNISSYNINDGVLQNSCFVDALNLVPHVFLLFITFPILFIGWGSQSSKVQIHH
NTWLHFPGHNLRWILTFALLFVHVCEIAEGIVSDSRRESRHLHLFMPAVMGFVATTTSIV
YYHNIETSNFPKLLLALFLYWVMAFITKTIKLVKYCQSGLDISNLRFCITGMMVILNGLL
MAVEINVIRVRRYVFFMNPQKVKPPEDLQDLGVRFLQPFVNLLSKATYWWMNTLIISAHK
KPIDLKAIGKLPIAMRAVTNYVCLKDAYEEQKKKVADHPNRTPSIWLAMYRAFGRPILLS
STFRYLADLLGFAGPLCISGIVQRVNETQNGTNNTTGISETLSSKEFLENAYVLAVLLFL
ALILQRTFLQASYYVTIETGINLRGALLAMIYNKILRLSTSNLSMGEMTLGQINNLVAIE
TNQLMWFLFLCPNLWAMPVQIIMGVILLYNLLGSSALVGAAVIVLLAPIQYFIATKLAEA
QKSTLDYSTERLKKTNEILKGIKLLKLYAWEHIFCKSVEETRMKELSSLKTFALYTSLSI
FMNAAIPIAAVLATFVTHAYASGNNLKPAEAFASLSLFHILVTPLFLLSTVVRFAVKAII
SVQKLNEFLLSDEIGDDSWRTGESSLPFESCKKHTGVQPKTINRKQPGRYHLDSYEQSTR
RLRPAETEDIAIKVTNGYFSWGSGLATLSNIDIRIPTGQLTMIVGQVGCGKSSLLLAILG
EMQTLEGKVHWSNVNESEPSFEATRSRNRYSVAYAAQKPWLLNATVEENITFGSPFNKQR
YKAVTDACSLQPDIDLLPFGDQTEIGERGINLSGGQRQRICVARALYQNTNIVFLDDPFS
ALDIHLSDHLMQEGILKFLQDDKRTLVLVTHKLQYLTHADWIIAMKDGSVLREGTLKDIQ
TKDVELYEHWKTLMNRQDQELEKDMEADQTTLERKTLRRAMYSREAKAQMEDEDEEEEEE
EDEDDNMSTVMRLRTKMPWKTCWRYLTSGGFFLLILMIFSKLLKHSVIVAIDYWLATWTS
EYSINNTGKADQTYYVAGFSILCGAGIFLCLVTSLTVEWMGLTAAKNLHHNLLNKIILGP
IRFFDTTPLGLILNRFSADTNIIDQHIPPTLESLTRSTLLCLSAIGMISYATPVFLVALL
PLGVAFYFIQKYFRVASKDLQELDDSTQLPLLCHFSETAEGLTTIRAFRHETRFKQRMLE
LTDTNNIAYLFLSAANRWLEVRTDYLGACIVLTASIASISGSSNSGLVGLGLLYALTITN
YLNWVVRNLADLEVQMGAVKKVNSFLTMESENYEGTMDPSQVPEHWPQEGEIKIHDLCVR
YENNLKPVLKHVKAYIKPGQKVGICGRTGSGKSSLSLAFFRMVDIFDGKIVIDGIDISKL
PLHTLRSRLSIILQDPILFSGSIRFNLDPECKCTDDRLWEALEIAQLKNMVKSLPGGLDA
VVTEGGENFSVGQRQLFCLARAFVRKSSILIMDEATASIDMATENILQKVVMTAFADRTV
VTIAHRVSSIMDAGLVLVFSEGILVECDTVPNLLAHKNGLFSTLVMTNK

NT seq 4650 nt +upstreamnt +downstreamnt
atgagcctttcattttgtggtaacaacatttcttcatataatatcaacgatggtgtacta
caaaattcctgctttgtggatgccctcaacctggtccctcatgtctttctgttgtttatc
acttttccaatattgtttattgggtgggggagccaaagctcaaaagtacaaattcaccac
aacacatggcttcattttccgggacataacctgagatggattcttacattcgctctcctg
tttgtgcatgtctgtgaaatagcagaaggcattgtttcagactcgcggcgggaatcaagg
cacctccacctctttatgccagccgtgatgggattcgttgccactacaacatcgatagtg
tattatcataatatcgaaacatcaaattttcctaaattacttttagccctgttcctgtat
tgggtaatggcctttattacaaaaacaataaaattggttaagtactgtcagtctggcttg
gacatatcaaacctgcgtttctgcatcacaggcatgatggtcatcttgaatgggctcttg
atggctgtggagatcaatgtcattcgagtcaggagatatgtatttttcatgaatcctcag
aaagtaaagcctcctgaagacctccaggatctgggagtgagatttcttcaaccatttgtg
aatttgctgtcaaaagcaacatactggtggatgaacacacttattatatctgctcacaaa
aagcctattgatctgaaggcaattggaaaattgccaatagcaatgagagcagtaacaaat
tatgtttgcctgaaagatgcatatgaagaacaaaagaaaaaagttgcagatcatccaaat
cggactccatctatatggcttgcaatgtacagagcttttgggcgaccaattctacttagt
agcacattccgctatctggctgatttactgggttttgctggacctctttgtatttctgga
atagttcagcgtgtgaatgaaacccagaatgggacaaataacacaactggaatttcagaa
accctctcatcaaaggaatttcttgaaaacgcttacgttctagcagttcttctcttcttg
gctcttattctgcaaaggacatttttgcaggcttcctactatgtaaccatagagactggc
attaacctccgtggagctctgctggccatgatttataataaaatccttaggctctctacg
tctaacttatccatgggggagatgactctggggcagatcaacaacttagtcgccattgaa
actaatcaactcatgtggtttttgttcctgtgtcctaatctatgggctatgcctgttcag
atcataatgggcgtgattctgctctataatttacttggatcaagtgcattggtcggtgca
gctgtcattgtgctccttgcgccaattcagtactttattgctacaaagttggcagaggct
cagaaaagtacacttgattattccactgagagactcaagaaaacaaatgaaatattgaaa
ggcatcaaacttctaaaattgtatgcctgggaacacattttctgcaaaagtgtggaggaa
acaagaatgaaagaactatctagtctcaaaacctttgcactatatacatcactctccatc
ttcatgaatgcagcaattcccatagcagctgttcttgctacatttgtgacccatgcgtat
gccagtggaaacaatctgaaacctgcagaggcctttgcttcactgtctctcttccatatc
ctggtcacaccactgttcctgctctccacggtggtcagatttgcagtcaaagccatcata
agtgttcaaaagctgaatgagtttctcttgagtgatgagattggtgacgacagttggcga
actggtgaaagttcgcttccttttgagtcctgtaagaagcacactggagttcagccaaaa
actataaacaggaaacagcctggaagatatcacctggacagctatgagcaatcaacacgg
cgtctacgtcccgcagaaacagaggacattgcaataaaggtcacaaatggatacttttca
tggggcagtggtttagctacattatccaatatagatattcgaattccaacaggtcagtta
accatgattgtgggccaagtaggatgtgggaagtcctctcttctccttgccatcctcggt
gagatgcagacattggaaggaaaagttcactggagcaatgtaaatgaatctgagccttct
tttgaagcaaccagaagtaggaacaggtactctgtggcatatgcagctcaaaagccttgg
ctattaaatgctacagtagaagaaaatattacttttggaagtccttttaacaaacagagg
tacaaagctgtcacagatgcctgttctcttcagccagatattgacttattaccatttgga
gatcaaactgaaattggagagaggggcatcaacctgagtgggggacagaggcagagaatc
tgtgtggcacgagcgctgtatcaaaacaccaacattgtctttttggatgatccattctca
gccctggacattcacttgagtgatcatttaatgcaggaggggattttgaaattcctgcaa
gatgacaaaaggacactcgttcttgtgactcacaaattacagtatctgacgcatgctgac
tggatcatagccatgaaagatggaagtgtcctaagagaaggaactttgaaggacattcaa
accaaagatgttgagctttatgaacactggaaaacacttatgaatcggcaagatcaagaa
ttagaaaaggatatggaagctgaccaaactactttagagaggaaaactctccgacgggcc
atgtattcaagagaagccaaagcccagatggaggacgaagacgaagaggaagaagaggag
gaagatgaggatgataacatgtccactgtaatgaggctcaggactaaaatgccatggaaa
acctgctggcgctacctgacatctggaggattcttcctgctcatcctgatgattttctct
aagcttttgaagcattcggtcattgtagctatagactattggctggccacatggacatcg
gagtacagtataaacaatactggaaaagctgatcagacctactatgtggctggctttagc
atactctgtggagcaggcattttcctttgccttgttacatccctcactgtagaatggatg
ggtctcacagctgccaaaaatcttcaccacaaccttctcaataagataatccttggacca
ataaggttttttgataccacacccctgggactgattctcaatcgcttttcagctgatact
aatatcattgatcagcacatccctccaaccttggaatctctaactcgctcaacactgctc
tgcctgtctgccattgggatgatttcttatgctactcctgtgttcctggttgctctcctg
ccccttggtgttgccttttattttatccagaaatactttcgggttgcctctaaggacctc
caggaacttgacgatagtacccagctccctctgctctgtcacttctcagaaacagcagaa
ggactcaccaccattcgggcctttaggcatgaaaccagatttaaacaacgtatgctggaa
ctgacggatacaaacaacattgcctacttatttctctcagctgccaacagatggctggag
gtcaggacggattatctgggagcttgcattgtcctcactgcatctatagcatccattagt
gggtcttcgaattctggattggtaggcttgggtcttctgtatgcacttacgataaccaat
tatttgaattgggttgtgaggaacttggctgacctggaggtccagatgggtgcagtgaag
aaggtgaacagtttcctgactatggagtcagagaactatgaaggcacaatggatccttct
caagttccagaacattggccacaagaaggggagatcaagatacatgatctgtgtgtcaga
tatgaaaataatctgaaacctgttcttaagcacgtcaaggcttacatcaaacctggacaa
aaggtgggcatatgtggtcgcactggcagtgggaaatcatcgttatctctggctttcttc
agaatggttgatatatttgatggaaaaattgtcattgatgggatagacatttccaaatta
ccactgcacacactacgttctagactttcaatcattctgcaggatccaatactattcagt
ggttccattagatttaatttagatccagagtgcaaatgcacagatgacagactctgggaa
gccttagaaattgctcagctgaagaatatggtcaaatctctacctggaggtctagatgcg
gttgtcactgaaggtggggagaattttagcgttggacagagacagctattttgccttgcc
agggcctttgtccgcaaaagcagcattcttattatggatgaggcaacagcttccattgac
atggccacagagaatattttgcaaaaagtagtaatgacagcctttgcagaccggaccgtg
gtgacaatagctcaccgtgtctcttctattatggatgcaggccttgttttagtcttttct
gagggtattttagtggagtgtgatactgtcccaaatttgctcgcccacaagaatggcctc
ttttccactttggtgatgaccaacaagtag

All links

Ontology (4)   
   KEGG BRITE (4)   
Pathway (1)   
   KEGG PATHWAY (1)   
Disease (6)   
   KEGG DISEASE (2)   
   OMIM (4)   
Drug (3)   
   KEGG DRUG (3)   
Genome (1)   
   KEGG GENOME (1)   
Gene (11)   
   KEGG ORTHOLOGY (1)   
   NCBI-Gene (1)   
   NCBI-GI (3)   
   UniGene (1)   
   HGNC (1)   
   HPRD (1)   
   ENSEMBL-HSA (1)   
   OC (1)   
   VEGA (1)   
Protein sequence (3)   
   UniProt (1)   
   RefSeq(pep) (2)   
DNA sequence (17)   
   RefSeq(nuc) (3)   
   GenBank (7)   
   EMBL (7)   
Protein domain (14)   
   Pfam (14)   
All databases (60)   

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