KEGG   Homo sapiens (human): 107Help
Entry
107               CDS       T01001                                 

Gene name
ADCY1, AC1
Definition
adenylate cyclase 1 (brain) (EC:4.6.1.1)
Orthology
K08041  
adenylate cyclase 1 [EC:4.6.1.1]
Organism
hsa  Homo sapiens (human)
Pathway
Purine metabolism
Rap1 signaling pathway
Calcium signaling pathway
cGMP-PKG signaling pathway
cAMP signaling pathway
Chemokine signaling pathway
Oocyte meiosis
Adrenergic signaling in cardiomyocytes
Vascular smooth muscle contraction
Gap junction
Platelet activation
Circadian entrainment
Long-term potentiation
Retrograde endocannabinoid signaling
Glutamatergic synapse
Cholinergic synapse
GABAergic synapse
Inflammatory mediator regulation of TRP channels
Insulin secretion
GnRH signaling pathway
Ovarian steroidogenesis
Progesterone-mediated oocyte maturation
Estrogen signaling pathway
Melanogenesis
Thyroid hormone synthesis
Oxytocin signaling pathway
Salivary secretion
Gastric acid secretion
Pancreatic secretion
Bile secretion
Morphine addiction
Chagas disease (American trypanosomiasis)
Amoebiasis
HTLV-I infection
Dilated cardiomyopathy
Drug target
Other: 
Brite
KEGG Orthology (KO) [BR:hsa00001]
 Metabolism
  Nucleotide metabolism
   00230 Purine metabolism
    107 (ADCY1)
 Environmental Information Processing
  Signal transduction
   04015 Rap1 signaling pathway
    107 (ADCY1)
   04020 Calcium signaling pathway
    107 (ADCY1)
   04024 cAMP signaling pathway
    107 (ADCY1)
   04022 cGMP - PKG signaling pathway
    107 (ADCY1)
 Cellular Processes
  Cell growth and death
   04114 Oocyte meiosis
    107 (ADCY1)
  Cellular commiunity
   04540 Gap junction
    107 (ADCY1)
 Organismal Systems
  Immune system
   04611 Platelet activation
    107 (ADCY1)
   04062 Chemokine signaling pathway
    107 (ADCY1)
  Endocrine system
   04911 Insulin secretion
    107 (ADCY1)
   04912 GnRH signaling pathway
    107 (ADCY1)
   04913 Ovarian Steroidogenesis
    107 (ADCY1)
   04915 Estrogen signaling pathway
    107 (ADCY1)
   04914 Progesterone-mediated oocyte maturation
    107 (ADCY1)
   04921 Oxytocin signaling pathway
    107 (ADCY1)
   04918 Thyroid hormone synthesis
    107 (ADCY1)
   04916 Melanogenesis
    107 (ADCY1)
  Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    107 (ADCY1)
   04270 Vascular smooth muscle contraction
    107 (ADCY1)
  Digestive system
   04970 Salivary secretion
    107 (ADCY1)
   04971 Gastric acid secretion
    107 (ADCY1)
   04972 Pancreatic secretion
    107 (ADCY1)
   04976 Bile secretion
    107 (ADCY1)
  Nervous system
   04724 Glutamatergic synapse
    107 (ADCY1)
   04727 GABAergic synapse
    107 (ADCY1)
   04725 Cholinergic synapse
    107 (ADCY1)
   04720 Long-term potentiation
    107 (ADCY1)
   04723 Retrograde endocannabinoid signaling
    107 (ADCY1)
  Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    107 (ADCY1)
  Environmental adaptation
   04713 Circadian entrainment
    107 (ADCY1)
 Human Diseases
  Substance dependence
   05032 Morphine addiction
    107 (ADCY1)
  Cardiovascular diseases
   05414 Dilated cardiomyopathy (DCM)
    107 (ADCY1)
  Infectious diseases
   05166 HTLV-I infection
    107 (ADCY1)
   05146 Amoebiasis
    107 (ADCY1)
   05142 Chagas disease (American trypanosomiasis)
    107 (ADCY1)
Enzymes [BR:hsa01000]
 4. Lyases
  4.6  Phosphorus-oxygen lyases
   4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)
    4.6.1.1  adenylate cyclase
     107 (ADCY1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
OMIM: 
HGNC: 
HPRD: 
Ensembl: 
Vega: 
UniProt: 
Position
7p13-p12
AA seq 338 aa AA seqDB search
MYGVFVRILTERSQRKAFLQARSCIEDRLRLEDENEKQERLLMSLLPRNVAMEMKEDFLK
PPERIFHKIYIQRHDNVSILFADIVGFTGLASQCTAQELVKLLNELFGKFDELATENHCR
RIKILGDCYYCVSGLTQPKTDHAHCCVEMGLDMIDTITSVAEATEVDLNMRVGLHTGRVL
CGVLGLRKWQYDVWSNDVTLANVMEAAGLPGKVHITKTTLACLNGDYEVEPGYGHERNSF
LKTHNIETFFIVPSHRRKIFPGLILSDIKPAKRMKFKTVCYLLVQLMHCRKMFKAEIPFS
NVMTCEDDDKVQIHPSLSGLDVLLGFWSPTLQRGRLCT
NT seq 1017 nt NT seq  +upstreamnt  +downstreamnt
atgtatggggtctttgtgcggattctgactgagcgttcacagaggaaggcgttcctgcag
gcccggagctgcattgaggaccgactgaggctggaggatgagaacgagaagcaggagcgg
ctcctcatgagcctcctgccccggaacgttgccatggagatgaaggaggacttcctgaag
ccccctgagaggattttccacaagatttacatccagaggcacgacaatgtgagcatcctg
tttgctgacatcgtgggtttcacgggcttggcatcccagtgcacagcccaggagctggtg
aaactcctcaatgagctcttcggcaagttcgatgaattagccacggagaaccactgtcgc
cgcatcaagattctcggggactgctactactgcgtgtcgggcctcacccagcccaagact
gaccatgcccactgctgtgtggagatgggactcgacatgattgataccatcacatctgtg
gctgaagccaccgaggtggatctgaacatgcgtgtgggtctgcacacgggcagggtcctc
tgtggtgtcctgggcttgcgcaagtggcagtacgacgtgtggtccaatgatgtgaccttg
gccaatgtcatggaagccgctggcctgccagggaaggttcatatcacaaagacgacccta
gcgtgcttgaatggggactacgaggtagaaccgggttacggacatgagaggaacagtttc
ttgaaaactcataacatcgaaaccttttttattgtgccatcccatcgccgaaagatattt
ccaggcctgattctctcagatataaaaccggccaaaaggatgaagttcaagactgtctgc
tacctgctggtgcagctcatgcactgccggaaaatgttcaaggccgagatccccttctcc
aatgtcatgacctgcgaggacgatgacaaggttcagatccatccctcactgagtggcctg
gatgtcctcctggggttttggtctcccaccctgcaacggggacgactgtgcacgtag

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