KEGG   Homo sapiens (human): 10908Help
Entry
10908             CDS       T01001                                 

Gene name
PNPLA6, BNHS, LNMS, NTE, NTEMND, OMCS, SPG39, iPLA2delta, sws
Definition
(RefSeq) patatin like phospholipase domain containing 6 (EC:3.1.1.5)
  KO
K14676  
lysophospholipid hydrolase [EC:3.1.1.5]
Organism
hsa  Homo sapiens (human)
Pathway
Glycerophospholipid metabolism
Disease
H00266  
Hereditary spastic paraplegia (SPG)
Brite
KEGG Orthology (KO) [BR:hsa00001]
 Metabolism
  Lipid metabolism
   00564 Glycerophospholipid metabolism
    10908 (PNPLA6)
Enzymes [BR:hsa01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.1  Carboxylic-ester hydrolases
    3.1.1.5  lysophospholipase
     10908 (PNPLA6)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-ProteinID: 
NCBI-GeneID: 
OMIM: 
HGNC: 
HPRD: 
Ensembl: 
Vega: 
UniProt: 
Position
19p13.2
AA seq 1365 aa AA seqDB search
MGTSSHGLATNSSGAKVAERDGFQDVLAPGEGSAGRICGAQPVPFVPQVLGVMIGAGVAV
VVTAVLILLVVRRLRVPKTPAPDGPRYRFRKRDKVLFYGRKIMRKVSQSTSSLVDTSVSA
TSRPRMRKKLKMLNIAKKILRIQKETPTLQRKEPPPAVLEADLTEGDLANSHLPSEVLYM
LKNVRVLGHFEKPLFLELCRHMVFQRLGQGDYVFRPGQPDASIYVVQDGLLELCLPGPDG
KECVVKEVVPGDSVNSLLSILDVITGHQHPQRTVSARAARDSTVLRLPVEAFSAVFTKYP
ESLVRVVQIIMVRLQRVTFLALHNYLGLTNELFSHEIQPLRLFPSPGLPTRTSPVRGSKR
MVSTSATDEPRETPGRPPDPTGAPLPGPTGDPVKPTSLETPSAPLLSRCVSMPGDISGLQ
GGPRSDFDMAYERGRISVSLQEEASGGSLAAPARTPTQEPREQPAGACEYSYCEDESATG
GCPFGPYQGRQTSSIFEAAKQELAKLMRIEDPSLLNSRVLLHHAKAGTIIARQGDQDVSL
HFVLWGCLHVYQRMIDKAEDVCLFVAQPGELVGQLAVLTGEPLIFTLRAQRDCTFLRISK
SDFYEIMRAQPSVVLSAAHTVAARMSPFVRQMDFAIDWTAVEAGRALYRQGDRSDCTYIV
LNGRLRSVIQRGSGKKELVGEYGRGDLIGVVEALTRQPRATTVHAVRDTELAKLPEGTLG
HIKRRYPQVVTRLIHLLSQKILGNLQQLQGPFPGSGLGVPPHSELTNPASNLATVAILPV
CAEVPMVAFTLELQHALQAIGPTLLLNSDIIRARLGASALDSIQEFRLSGWLAQQEDAHR
IVLYQTDASLTPWTVRCLRQADCILIVGLGDQEPTLGQLEQMLENTAVRALKQLVLLHRE
EGAGPTRTVEWLNMRSWCSGHLHLRCPRRLFSRRSPAKLHELYEKVFSRRADRHSDFSRL
ARVLTGNTIALVLGGGGARGCSHIGVLKALEEAGVPVDLVGGTSIGSFIGALYAEERSAS
RTKQRAREWAKSMTSVLEPVLDLTYPVTSMFTGSAFNRSIHRVFQDKQIEDLWLPYFNVT
TDITASAMRVHKDGSLWRYVRASMTLSGYLPPLCDPKDGHLLMDGGYINNLPADIARSMG
AKTVIAIDVGSQDETDLSTYGDSLSGWWLLWKRLNPWADKVKVPDMAEIQSRLAYVSCVR
QLEVVKSSSYCEYLRPPIDCFKTMDFGKFDQIYDVGYQYGKAVFGGWSRGNVIEKMLTDR
RSTDLNESRRADVLAFPSSGFTDLAEIVSRIEPPTSYVSDGCADGEESDCLTEYEEDAGP
DCSRDEGGSPEGASPSTASEMEEEKSILRQRRCLPQEPPGSATDA
NT seq 4098 nt NT seq  +upstreamnt  +downstreamnt
atggggacatcgagtcacgggctggctacgaactcctcgggggcgaaggtggcggagagg
gatgggttccaggacgtcctggcgcccggggaaggctcggcgggacggatttgcggtgcg
cagccagtgccgttcgtccctcaggtgcttggcgtgatgatcggggccggagtggcggtg
gtggtcacggccgtgctcatcctcctggtggtgcggaggctgcgagtgccaaaaacccca
gccccggatggcccccggtatcggttccggaagagggacaaagtgctcttctatggccgg
aagattatgcggaaggtgtcacaatccacctcctccctcgtggatacctctgtctccgcc
acctcccggccacgcatgaggaagaaactgaagatgctcaacattgccaagaagatcctg
cgcatccagaaagagacgcccacgctgcagcggaaggagcccccgcccgcagtgctagaa
gctgacctgaccgagggcgacctggctaactcccatctgccctctgaagtgctttatatg
ctcaagaacgtccgggtgctgggccacttcgagaagccactcttcctggagctctgccgc
cacatggtcttccagcggctgggccagggtgactacgtcttccggccgggccagccagat
gccagcatctacgtggtgcaggacgggctgctggagctctgtctgccagggcctgacggg
aaggagtgtgtggtgaaggaagtggttcctggggacagcgtcaacagccttctcagcatc
ctggatgtcatcaccggtcaccagcatccccagcggaccgtgtctgcccgggcggcccgg
gactccacggtgctgcgcctgccggtggaagcattctccgcggtcttcaccaagtacccg
gagagcttggtgcgggtcgtgcagatcatcatggtgcggctgcagcgagtcaccttcctg
gcactgcacaactacctgggtctgaccaatgagctcttcagccacgagatccagcccctg
cgtctgttccccagccccggcctcccaactcgcaccagccctgtgcggggctccaagaga
atggtcagcacctcagctacagacgagcccagggagaccccagggcggccacccgatccc
accggggccccgctgcctggacctacaggggaccctgtgaagcccacatccctggaaacc
ccctcggcccctctgctgagccgctgcgtctccatgccaggggacatctcaggcttgcag
ggtggcccccgctccgacttcgacatggcctatgagcgtggccggatctccgtgtccctg
caggaagaggcctccggggggtccctggcagcccccgctcggacccccactcaggagcct
cgtgagcagccggcaggcgcctgtgaatacagctactgtgaggatgagtcggccactggt
ggctgccctttcgggccctaccagggccgccagaccagcagcatcttcgaggcagcaaag
caggagctggccaagctgatgcggattgaggacccctccctcctgaacagcagagtcttg
ctgcaccacgccaaagctggcaccatcattgcccgccagggagaccaggacgtgagcctg
cacttcgtgctctggggctgcctgcacgtgtaccagcgcatgatcgacaaggcggaggac
gtgtgcctgttcgtagcgcagcccggggaactggtggggcagctggcggtgctcactggc
gaacctctcatcttcacactgcgagcccaacgcgactgcaccttcctgcggatctccaag
tccgacttctatgagatcatgcgcgcacagcccagtgtggtgctgagtgcggcgcacacg
gtggcagccaggatgtcgcccttcgtgcgccagatggacttcgccatcgactggactgca
gtggaggcgggacgcgcgctgtacaggcagggcgaccgctccgactgcacttacatcgtg
ctcaatgggcggctgcgtagcgtgatccagcgaggcagtggcaagaaggagctggtgggc
gagtacggccgcggcgacctcatcggcgtggtggaggcactgacccggcagccgcgagcc
acgacggtgcacgcggtgcgcgacacggagctggccaagcttcccgagggcaccttgggt
cacatcaaacgccggtacccgcaggtcgtgacccgccttatccacctactgagccagaaa
attctagggaatttgcagcagctgcaaggacccttcccaggctctgggttgggtgtgccc
ccacactcggaactcaccaacccagccagcaacctggcaactgtggcaatcctgcctgtg
tgtgctgaggtccccatggtggccttcacgctggagctgcagcacgccctgcaggccatc
ggtccgacgctactccttaacagtgacatcatccgggcacgcctgggggcctccgcactg
gatagcatccaagagttccggctgtcagggtggctggcccagcaggaggatgcacaccgt
atcgtactctaccagacggacgcctcgctgacgccctggaccgtgcgctgcctgcgacag
gccgactgcatcctcattgtgggcctgggggaccaggagcctaccctcggccagctggag
cagatgctggagaacacggctgtgcgcgcccttaagcagctagtcctgctccaccgagag
gagggcgcgggccccacgcgcaccgtggagtggctaaatatgcgcagctggtgctcgggg
cacctgcacctgcgctgtccgcgccgcctcttttcgcgccgcagccctgccaagctgcat
gagctctacgagaaggttttctccaggcgcgcggaccggcacagcgacttctcccgcttg
gcgagggtgctcacggggaacaccattgcccttgtgctaggcgggggcggggccaggggc
tgctcgcacatcggagtactaaaggcattagaggaggcgggggtccccgtggacctggtg
ggcggcacgtccattggctctttcatcggagcgttgtacgcggaggagcgcagcgccagc
cgcacgaagcagcgggcccgggagtgggccaagagcatgacttcggtgctggaacctgtg
ttggacctcacgtacccagtcacctccatgttcactgggtctgcctttaaccgcagcatc
catcgggtcttccaggataagcagattgaggacctgtggctgccttacttcaacgtgacc
acagatatcaccgcctcagccatgcgagtccacaaagatggctccctgtggcggtacgtg
cgcgccagcatgacgctgtcgggctacctgcccccgctgtgcgaccccaaggacgggcac
ctactcatggatggcggctacatcaacaatctgccagcggacatcgcccgcagcatgggt
gccaaaacggtcatcgccattgacgtggggagccaggatgagacggacctcagcacctac
ggggacagcctgtccggctggtggctgctgtggaagcggctgaatccctgggctgacaag
gtaaaggttccagacatggctgaaatccagtcccgcctggcctacgtgtcctgtgtgcgg
cagctagaggttgtcaagtccagctcctactgcgagtacctgcgcccgcccatcgactgc
ttcaagaccatggactttgggaagttcgaccagatctatgatgtgggctaccagtacggg
aaggcggtgtttggaggctggagccgtggcaacgtcattgagaaaatgctcacagaccgg
cggtctacagaccttaatgagagccgccgtgcagacgtgcttgccttcccaagctctggc
ttcactgacttggcagagattgtgtcccggattgagccccccacgagctatgtctctgat
ggctgtgctgacggagaggagtcagattgtctgacagagtatgaggaggacgccggaccc
gactgctcgagggatgaaggggggtcccccgagggcgcaagccccagcactgcctccgag
atggaggaggagaagtcgattctccggcaacgacgctgtctgccccaggagccgcccggc
tcagccacagatgcctga

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