KEGG   Homo sapiens (human): 11060
Entry
11060             CDS       T01001                                 
Symbol
WWP2, AIP2, WWp2-like
Name
(RefSeq) WW domain containing E3 ubiquitin protein ligase 2
  KO
K05630  NEDD4-like E3 ubiquitin-protein ligase WWP2 [EC:2.3.2.26]
Organism
hsa  Homo sapiens (human)
Pathway
hsa04120  Ubiquitin mediated proteolysis
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04120 Ubiquitin mediated proteolysis
    11060 (WWP2)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04121 Ubiquitin system [BR:hsa04121]
    11060 (WWP2)
Enzymes [BR:hsa01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.2  Aminoacyltransferases
    2.3.2.26  HECT-type E3 ubiquitin transferase
     11060 (WWP2)
Ubiquitin system [BR:hsa04121]
 Ubiquitin ligases (E3)
  HECT type E3
   11060 (WWP2)
SSDB
Motif
Pfam: HECT WW
Other DBs
NCBI-GeneID: 11060
NCBI-ProteinID: NP_001257383
OMIM: 602308
HGNC: 16804
Ensembl: ENSG00000198373
UniProt: O00308
Structure
Position
16:69762332..69941739
AA seq 870 aa
MASASSSRAGVALPFEKSQLTLKVVSAKPKVHNRQPRINSYVEVAVDGLPSETKKTGKRI
GSSELLWNEIIILNVTAQSHLDLKVWSCHTLRNELLGTASVNLSNVLKNNGGKMENMQLT
LNLQTENKGSVVSGGELTIFLDGPTVDLGNVPNGSALTDGSQLPSRDSSGTAVAPENRHQ
PPSTNCFGGRSRTHRHSGASARTTPATGEQSPGARSRHRQPVKNSGHSGLANGTVNDEPT
TATDPEEPSVVGVTSPPAAPLSVTPNPNTTSLPAPATPAEGEEPSTSGTQQLPAAAQAPD
ALPAGWEQRELPNGRVYYVDHNTKTTTWERPLPPGWEKRTDPRGRFYYVDHNTRTTTWQR
PTAEYVRNYEQWQSQRNQLQGAMQHFSQRFLYQSSSASTDHDPLGPLPPGWEKRQDNGRV
YYVNHNTRTTQWEDPRTQGMIQEPALPPGWEMKYTSEGVRYFVDHNTRTTTFKDPRPGFE
SGTKQGSPGAYDRSFRWKYHQFRFLCHSNALPSHVKISVSRQTLFEDSFQQIMNMKPYDL
RRRLYIIMRGEEGLDYGGIAREWFFLLSHEVLNPMYCLFEYAGKNNYCLQINPASSINPD
HLTYFRFIGRFIAMALYHGKFIDTGFTLPFYKRMLNKRPTLKDLESIDPEFYNSIVWIKE
NNLEECGLELYFIQDMEILGKVTTHELKEGGESIRVTEENKEEYIMLLTDWRFTRGVEEQ
TKAFLDGFNEVAPLEWLRYFDEKELELMLCGMQEIDMSDWQKSTIYRHYTKNSKQIQWFW
QVVKEMDNEKRIRLLQFVTGTCRLPVGGFAELIGSNGPQKFCIDKVGKETWLPRSHTCFN
RLDLPPYKSYEQLREKLLYAIEETEGFGQE
NT seq 2613 nt   +upstreamnt  +downstreamnt
atggcatctgccagctctagccgggcaggagtggccctgccttttgagaagtctcagctc
actttgaaagtggtgtccgcaaagcccaaggtgcataatcgtcaacctcgaattaactcc
tacgtggaggtggcggtggatggactccccagtgagaccaagaagactgggaagcgcatt
gggagctctgagcttctctggaatgagatcatcattttgaatgtcacggcacagagtcat
ttagatttaaaggtctggagctgccataccttgagaaatgaactgctaggcaccgcatct
gtcaacctctccaacgtcttgaagaacaatgggggcaaaatggagaacatgcagctgacc
ctgaacctgcagacggagaacaaaggcagcgttgtctcaggcggagagctgacaattttc
ctggacgggccaactgttgatctgggaaatgtgcctaatggcagtgccctgacagatgga
tcacagctgccttcgagagactccagtggaacagcagtagctccagagaaccggcaccag
ccccccagcacaaactgctttggtggaagatcccggacgcacagacattcgggtgcttca
gccagaacaaccccagcaaccggcgagcaaagccccggtgctcggagccggcaccgccag
cccgtcaagaactcaggccacagtggcttggccaatggcacagtgaatgatgaacccaca
acagccactgatcccgaagaaccttccgttgttggtgtgacgtccccacctgctgcaccc
ttgagtgtgaccccgaatcccaacacgacttctctccctgccccagccacaccggctgaa
ggagaggaacccagcacttcgggtacacagcagctcccagcggctgcccaggcccccgac
gctctgcctgctggatgggaacagcgagagctgcccaacggacgtgtctattatgttgac
cacaataccaagaccaccacctgggagcggccccttcctccaggctgggaaaaacgcaca
gatccccgaggcaggttttactatgtggatcacaatactcggaccaccacctggcagcgt
ccgaccgcggagtacgtgcgcaactatgagcagtggcagtcgcagcggaatcagctccag
ggggccatgcagcacttcagccaaagattcctctaccagtcttcgagtgcttcgactgac
catgatcccctgggccccctccctcctggctgggagaagagacaggacaatggacgggtg
tattacgtgaaccataacactcgcacgacccagtgggaggatccccggacccaggggatg
atccaggaaccagctctgcccccaggatgggagatgaaatacaccagcgagggggtgcga
tactttgtggaccacaatacccgcaccaccacctttaaggatcctcgcccggggtttgag
tcggggacgaagcaaggttcccctggtgcttatgaccgcagttttcggtggaagtatcac
cagttccgtttcctctgccattcaaatgccctacctagccacgtgaagatcagcgtttcc
aggcagacgcttttcgaagattccttccaacagatcatgaacatgaaaccctatgacctg
cgccgccggctctacatcatcatgcgtggcgaggagggcctggactatgggggcatcgcc
agagagtggtttttcctcctgtctcatgaggtgctcaaccctatgtattgtttatttgaa
tatgccggaaagaacaattactgcctgcagatcaaccccgcctcctccatcaacccggac
cacctcacctactttcgctttataggcagattcatcgccatggcgctgtaccatggaaag
ttcatcgacacgggcttcaccctccctttctacaagcggatgctcaataagagaccaacc
ctgaaagacctggagtccattgaccctgagttctacaactccattgtctggatcaaagag
aacaacctggaagaatgtggcctggagctgtacttcatccaggacatggagatactgggc
aaggtgacgacccacgagctgaaggagggcggcgagagcatccgggtcacagaggagaac
aaggaagagtacatcatgctgctgactgactggcgtttcacccgaggcgtggaagagcag
accaaagccttcctggatggcttcaacgaggtggccccgctggagtggctgcgctacttt
gacgagaaagagctggagctgatgctgtgcggcatgcaggagatagacatgagcgactgg
cagaagagcaccatctaccggcactacaccaagaacagcaagcagatccagtggttctgg
caggtggtgaaggagatggacaacgagaagaggatccggctgctgcagtttgtcaccggt
acctgccgcctgcccgtcgggggatttgccgaactcatcggtagcaacggaccacagaag
ttttgcattgacaaagttggcaaggaaacctggctgcccagaagccacacctgcttcaac
cgtctggatcttccaccctacaagagctacgaacagctgagagagaagctgctgtatgcc
attgaggagaccgagggctttggacaggagtaa

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (1)   
   KEGG PATHWAY (1)   
Disease (1)   
   OMIM (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (25)   
   KEGG ORTHOLOGY (1)   
   RefGene (16)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (3)   
   OC (1)   
Protein sequence (29)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (27)   
DNA sequence (69)   
   RefSeq(nuc) (27)   
   GenBank (21)   
   EMBL (21)   
3D Structure (10)   
   PDB (10)   
Protein domain (2)   
   Pfam (2)   
All databases (142)   

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