KEGG T01001: 11128

Homo sapiens (human): 11128

Entry

11128 CDS T01001

Gene name

POLR3A, ADDH, HLD7, RPC1, RPC155, hRPC155

Definition

polymerase (RNA) III (DNA directed) polypeptide A, 155kDa (EC:2.7.7.6)

Orthology

K03018

DNA-directed RNA polymerase III subunit RPC1 [EC:2.7.7.6]

Organism

hsa Homo sapiens (human)

Pathway

hsa00230	Purine metabolism
hsa00240	Pyrimidine metabolism
hsa01100	Metabolic pathways
hsa03020	RNA polymerase
hsa04623	Cytosolic DNA-sensing pathway
hsa05169	Epstein-Barr virus infection

Module

hsa_M00181

RNA polymerase III, eukaryotes

Class

Metabolism; Nucleotide metabolism; Purine metabolism [PATH:hsa00230]
Metabolism; Nucleotide metabolism; Pyrimidine metabolism [PATH:hsa00240]
Genetic Information Processing; Transcription; RNA polymerase [PATH:hsa03020]
Organismal Systems; Immune system; Cytosolic DNA-sensing pathway [PATH:hsa04623]
Human Diseases; Infectious diseases; Epstein-Barr virus infection [PATH:hsa05169]

SSDB

Motif

Pfam:

RNA_pol_Rpb1_1 RNA_pol_Rpb1_5 RNA_pol_Rpb1_2 RNA_pol_Rpb1_3 RNA_pol_Rpb1_4

Other DBs

NCBI-GI:

NCBI-GeneID:

OMIM:

HGNC:

HPRD:

Ensembl:

Vega:

UniProt:

Position

10q22-q23

AA seq 1390 aa
MVKEQFRETDVAKKISHICFGMKSPEEMRQQAHIQVVSKNLYSQDNQHAPLLYGVLDHRM
GTSEKDRPCETCGKNLADCLGHYGYIDLELPCFHVGYFRAVIGILQMICKTCCHIMLSQE
EKKQFLDYLKRPGLTYLQKRGLKKKISDKCRKKNICHHCGAFNGTVKKCGLLKIIHEKYK
TNKKVVDPIVSNFLQSFETAIEHNKEVEPLLGRAQENLNPLVVLNLFKRIPAEDVPLLLM
NPEAGKPSDLILTRLLVPPLCIRPSVVSDLKSGTNEDDLTMKLTEIIFLNDVIKKHRISG
AKTQMIMEDWDFLQLQCALYINSELSGIPLNMAPKKWTRGFVQRLKGKQGRFRGNLSGKR
VDFSGRTVISPDPNLRIDEVAVPVHVAKILTFPEKVNKANINFLRKLVQNGPEVHPGANF
IQQRHTQMKRFLKYGNREKMAQELKYGDIVERHLIDGDVVLFNRQPSLHKLSIMAHLARV
KPHRTFRFNECVCTPYNADFDGDEMNLHLPQTEEAKAEALVLMGTKANLVTPRNGEPLIA
AIQDFLTGAYLLTLKDTFFDRAKACQIIASILVGKDEKIKVRLPPPTILKPVTLWTGKQI
FSVILRPSDDNPVRANLRTKGKQYCGKGEDLCANDSYVTIQNSELMSGSMDKGTLGSGSK
NNIFYILLRDWGQNEAADAMSRLARLAPVYLSNRGFSIGIGDVTPGQGLLKAKYELLNAG
YKKCDEYIEALNTGKLQQQPGCTAEETLEALILKELSVIRDHAGSACLRELDKSNSPLTM
ALCGSKGSFINISQMIACVGQQAISGSRVPDGFENRSLPHFEKHSKLPAAKGFVANSFYS
GLTPTEFFFHTMAGREGLVDTAVKTAETGYMQRRLVKSLEDLCSQYDLTVRSSTGDIIQF
IYGGDGLDPAAMEGKDEPLEFKRVLDNIKAVFPCPSEPALSKNELILTTESIMKKSEFLC
CQDSFLQEIKKFIKGVSEKIKKTRDKYGINDNGTTEPRVLYQLDRITPTQVEKFLETCRD
KYMRAQMEPGSAVGALCAQSIGEPGTQMTLKTFHFAGVASMNITLGVPRIKEIINASKAI
STPIITAQLDKDDDADYARLVKGRIEKTLLGEISEYIEEVFLPDDCFILVKLSLERIRLL
RLEVNAETVRYSICTSKLRVKPGDVAVHGEAVVCVTPRENSKSSMYYVLQFLKEDLPKVV
VQGIPEVSRAVIHIDEQSGKEKYKLLVEGDNLRAVMATHGVKGTRTTSNNTYEVEKTLGI
EAARTTIINEIQYTMVNHGMSIDRRHVMLLSDLMTYKGEVLGITRFGLAKMKESVLMLAS
FEKTADHLFDAAYFGQKDSVCGVSECIIMGIPMNIGTGLFKLLHKADRDPNPPKRPLIFD
TNEFHIPLVT

NT seq 4173 nt +upstreamnt +downstreamnt
atggtgaaggagcagttccgggagacggatgtggccaagaaaataagccacatctgtttt
ggaatgaagtcacctgaggagatgcgccagcaggcgcacatccaagttgtgagtaagaac
ctgtacagccaggacaaccaacatgcccccttgctatatggggtgctcgaccataggatg
ggtacgagtgagaaggatcgtccatgtgaaacctgtgggaaaaacttggctgactgtcta
ggccactatgggtatatcgacctggagttgccgtgttttcatgtagggtacttcagagca
gtcataggcatcttacagatgatctgcaaaacctgctgccacatcatgctgtcccaagag
gagaagaagcagtttctggactatctaaagaggcccggcctgacctaccttcagaagcga
ggactgaaaaagaaaatctctgacaagtgccggaagaaaaacatctgccatcactgtggc
gcttttaatggtaccgtaaagaagtgtggactgctgaaaataattcatgagaaatacaag
accaacaaaaaagtggtggatcccattgtatcaaatttccttcagtcttttgaaacagcc
attgaacataataaagaagtggagcctctgctgggaagggcacaggaaaacttgaatccc
ttagtagttctgaatttatttaaacgaatcccagctgaagatgttcctctacttctgatg
aacccagaagccggaaagccgtctgatttgattctcacacgacttttggtgcctcctttg
tgtatcagaccctccgttgtgagtgatttgaagtctggcaccaatgaagatgatctgaca
atgaaactgacagaaatcattttcctaaacgatgttattaaaaagcatcggatctcagga
gccaagacccagatgatcatggaggactgggatttcctgcagctgcagtgtgccctctac
attaacagtgagctctcgggcattcccctcaacatggcacccaagaagtggaccagaggc
ttcgtccaacgcctgaagggaaaacagggtcgatttagaggaaatctctcaggaaagaga
gtggatttttctggcagaacagtcatctcgcccgaccccaacctccggattgatgaggta
gctgtgccagttcatgtggccaaaattctaacttttcctgagaaggtaaacaaagcaaac
atcaatttcttgaggaaactggttcaaaacggccctgaggttcacccaggagcaaacttc
attcagcagagacatacgcagatgaaaaggtttttgaaatacggaaatcgagaaaagatg
gctcaagagctcaagtatggtgacatcgtagagagacacctcatcgatggagatgtggtg
ctgttcaatcggcagccctcgctgcacaaattgagcattatggctcatctggccagggtc
aagccccaccggaccttcagatttaatgagtgtgtctgtacaccctataatgctgacttt
gatggtgatgaaatgaaccttcatcttcctcaaacagaagaagctaaagcagaggccctt
gttctgatggggactaaagcaaatcttgtaaccccgaggaatggggaaccgctgattgct
gctattcaggattttctaacaggtgcctatctcctcactctcaaggacactttctttgat
cgagccaaggcttgccaaatcattgcttcaatactggttggcaaggatgagaaaattaaa
gttcgcctcccaccgcctacaatcctaaagcctgtcaccctgtggacgggaaagcagatc
ttcagtgtcatcctcaggcctagcgatgacaatccagtgagggccaacctgcgaaccaag
ggcaagcagtactgtggcaaaggggaagatctctgtgccaatgattcctatgttacaatc
cagaacagtgagttgatgagtggcagcatggacaaaggaaccctagggtcaggatccaag
aacaatattttttacattttgctgcgagactggggacagaatgaagctgcagatgccatg
tcacggctcgccaggctggctcctgtctacctgtctaaccgtggtttctcaattgggatc
ggtgatgtcacacctggccaaggactgctgaaggccaagtatgagttgctgaatgccggc
tacaagaaatgtgatgagtacatcgaagccctgaacacgggcaagctgcagcagcagcct
ggctgcactgctgaggagaccctggaggcactgatcctgaaggagctgtctgtgatccgt
gaccacgctggcagtgcctgcctccgggagctggacaagagcaacagccccctcaccatg
gctctgtgcggctccaaaggttccttcattaacatatcacagatgattgcctgtgtggga
cagcaggccatcagtggctctcgagtgccagacggctttgaaaacaggtccttgcctcat
tttgaaaaacactcaaagctcccagctgccaaaggctttgtggctaatagcttttattcc
ggtttgacaccaactgagtttttcttccacacaatggccggccgggaaggtctagtcgac
acggctgtaaagacagctgaaacgggatacatgcagcgaaggcttgtcaaatctcttgaa
gatctttgctcccagtatgatctgacagtccgaagctctactggcgatattatccagttc
atttatggaggagatggcttagatcctgcagctatggagggaaaagatgaacctttggag
tttaaaagggttctggacaacatcaaagcagtcttcccgtgtcccagtgagcctgctctc
agcaaaaacgagctgatcctgaccacagagtccatcatgaagaagagtgagttcctctgc
tgccaggacagcttcctgcaggaaataaaaaaattcattaagggggtctctgagaagatc
aagaaaaccagagataaatatggcatcaatgataacggcacaacagagccccgtgtgctg
taccagctggaccgcatcacccccacccaagtagaaaagtttctggagacctgtagggac
aagtacatgagggcacagatggagccaggttctgcagtgggtgctctgtgtgcccagagc
attggtgagccaggcacccagatgaccctgaagactttccactttgcaggtgtggcctcc
atgaacatcaccctgggcgtgccccggattaaagagatcatcaacgcttccaaggccatc
agcactccaattatcacagcacagctagacaaggatgacgacgcggattatgctcgcctc
gtgaaagggagaattgagaaaaccctcttgggagagatttccgagtatattgaagaagtg
tttcttcctgatgactgctttattctcgtcaagctctccctggaacggattaggcttctg
agactggaagtgaacgctgagacagtgagatattccatctgcacatccaagctccgtgtg
aagcccggtgatgtggctgttcatggtgaggctgtggtgtgtgtcacccccagagagaac
agcaagagctccatgtactacgtgctgcagttcctgaaagaggatctccccaaggtggtg
gtgcagggcattccagaggtgtccagagctgtcatccacattgacgagcagagtggaaag
gagaagtacaagcttctggtggaaggtgataacctgcgggcagtcatggccacacacggt
gtgaagggcacccgaaccacctccaataacacctatgaggtggagaaaactctgggcatc
gaggccgcccggacaacgatcatcaatgaaatccagtacaccatggtgaaccacggcatg
agcatcgacaggaggcacgtgatgctgctctccgacctcatgacctacaagggtgaagtc
ctgggcatcactaggtttggcctggccaagatgaaggagagtgtgctgatgctggcctcc
tttgagaagacggctgaccatctctttgacgctgcctacttcgggcagaaggactctgtg
tgtggggtgtctgagtgcatcatcatgggaatcccaatgaacattggaaccgggctcttc
aagctgcttcacaaggctgacagggacccgaaccctcccaagaggcccctgatcttcgac
acaaatgaattccacatcccccttgtcacatag

All links

Pathway (7)   
   KEGG PATHWAY (6)   
   KEGG MODULE (1)   
Disease (2)   
   OMIM (2)   
Chemical substance (6)   
   KEGG COMPOUND (6)   
Chemical reaction (5)   
   KEGG ENZYME (1)   
   KEGG REACTION (4)   
Genome (1)   
   KEGG GENOME (1)   
Gene (17)   
   KEGG ORTHOLOGY (1)   
   NCBI-Gene (1)   
   NCBI-GI (9)   
   UniGene (1)   
   HGNC (1)   
   HPRD (1)   
   ENSEMBL-HSA (1)   
   OC (1)   
   VEGA (1)   
Protein sequence (2)   
   UniProt (1)   
   RefSeq(pep) (1)   
DNA sequence (27)   
   RefSeq(nuc) (1)   
   GenBank (13)   
   EMBL (13)   
Protein domain (5)   
   Pfam (5)   
All databases (72)   

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