KEGG T01001: 116984

Homo sapiens (human): 116984

Entry

116984 CDS T01001

Gene name

ARAP2, CENTD1, PARX

Definition

(RefSeq) ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2

K18440

Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 2

Organism

hsa Homo sapiens (human)

Pathway

hsa04144

Endocytosis

Brite

KEGG Orthology (KO) [BR:hsa00001]
Cellular Processes
  Transport and catabolism
   04144 Endocytosis
    116984 (ARAP2)
Membrane trafficking [BR:hsa04131]
Endocytosis
  Arf GTPases and associated proteins
   Arf associated proteins
    116984 (ARAP2)
Endosome - Golgi transport
   Arf GTPase associated proteins
    116984 (ARAP2)
Others
  Rho GTPase associated proteins
   Rho GTPase-activating proteins
    116984 (ARAP2)

SSDB

Motif

Pfam:

PH RhoGAP ArfGap SAM_1 PH_6 SAM_2 PH_3 PH_11 RA DNA_pol_phi PH_8 Mcp5_PH

Other DBs

NCBI-GeneID:

NCBI-ProteinID:

OMIM:

HGNC:

Ensembl:

Vega:

Pharos:

Q8WZ64(Tbio)

UniProt:

Q8WZ64 A7E2A5

Structure

PDB:

2COD 1X40

Position

4p14

AA seq 1704 aa
MSSVSEVNVDIKDFLMSINLEQYLLHFHESGFTTVKDCAAINDSLLQKIGISPTGHRRRI
LKQLQIILSKMQDIPIYANVHKTKKNDDPSKDYHVPSSDQNICIELSNSGSVQTSSPPQL
ETVRKNLEDSDASVERSQYPQSDDKLSPPKRDFPTAEEPHLNLGSLNDSLFGSDNIKIES
LITKKTVDHTVEEQQTEKVKLITENLSKLPNADSECLSFVGCSTSGTNSGNGTNGLLEGS
PPSPFFKFQGEMIVNDLYVPSSPILAPVRSRSKLVSRPSRSFLLRHRPVPEIPGSTKGVS
GSYFRERRNVATSTEKSVAWQNSNEENSSSIFPYGETFLFQRLENSKKRSIKNEFLTQGE
ALKGEAATATNSFIIKSSIYDNRKEKISEDKVEDIWIPREDKNNFLIDTASESEYSTVEE
CFQSLRRKNSKASKSRTQKALILDSVNRHSYPLSSTSGNADSSAVSSQAISPYACFYGAS
AKKVKSGWLDKLSPQGKRMFQKRWVKFDGLSISYYNNEKEMYSKGIIPLSAISTVRVQGD
NKFEVVTTQRTFVFRVEKEEERNDWISILLNALKSQSLTSQSQAVVTPEKCGYLELRGYK
AKIFTVLSGNSVWLCKNEQDFKSGLGITIIPMNVANVKQVDRTVKQSFEIITPYRSFSFT
AETEKEKQDWIEAVQQSIAETLSDYEVAEKIWFNESNRSCADCKAPDPDWASINLCVVIC
KKCAGQHRSLGPKDSKVRSLKMDASIWSNELIELFIVIGNKRANDFWAGNLQKDEELHMD
SPVEKRKNFITQKYKEGKFRKTLLASLTKEELNKALCAAVVKPDVLETMALLFSGADVMC
ATGDPVHSTPYLLAKKAGQSLQMEFLYHNKFSDFPQHDIHSEGVLSQESSQSTFLCDFLY
QAPSAASKLSSEKKLLEETNKKWCVLEGGFLSYYENDKSTTPNGTININEVICLAIHKED
FYLNTGPIFIFEIYLPSERVFLFGAETSQAQRKWTEAIAKHFVPLFAENLTEADYDLIGQ
LFYKDCHALDQWRKGWFAMDKSSLHFCLQMQEVQGDRMHLRRLQELTISTMVQNGEKLDV
LLLVEKGRTLYIHGHTKLDFTVWHTAIEKAAGTDGNALQDQQLSKNDVPIIVNSCIAFVT
QYGLGCKYIYQKNGDPLHISELLESFKKDARSFKLRAGKHQLEDVTAVLKSFLSDIDDAL
LTKELYPYWISALDTQDDKERIKKYGAFIRSLPGVNRATLAAIIEHLYRVQKCSEINHMN
AHNLALVFSSCLFQTKGQTSEEVNVIEDLINNYVEIFEVKEDQVKQMDIENSFITKWKDT
QVSQAGDLLIEVYVERKEPDCSIIIRISPVMEAEELTNDILAIKNIIPTKGDIWATFEVI
ENEELERPLHYKENVLEQVLRWSSLAEPGSAYLVVKRFLTADTIKHCSDRSTLGSIKEGI
LKIKEEPSKILSGNKFQDRYFVLRDGFLFLYKDVKSSKHDKMFSLSSMKFYRGVKKKMKP
PTSWGLTAYSEKHHWHLCCDSSRTQTEWMTSIFIAQHEYDIWPPAGKERKRSITKNPKIG
GLPLIPIQHEGNATLARKNIESARAELERLRLSEKCDKESVDSSLKERASMVAHCLEHKD
DKLRNRPRKHRSFNCLEDTEPEAPLGQPKGHKGLKTLRKTEDRNSKATLDSDHKLPSRVI
EELNVVLQRSRTLPKELQDEQILK

NT seq 5115 nt +upstreamnt +downstreamnt
atgtcctcagtcagtgaagtaaatgtggatataaaagatttcctaatgagcattaatttg
gagcagtatctcttacatttccatgagtctggttttactactgtgaaggactgtgcagca
ataaatgacagcctgctgcagaaaattggaatatcacctacaggtcaccgtaggaggata
cttaaacagttacagataatcttgtcaaaaatgcaagatattccaatatatgcaaatgtt
cataaaactaagaagaatgatgacccttcaaaggattaccatgttccatcttctgatcag
aatatctgcatagaactttccaattctggtagtgttcagacatctagcccaccgcagttg
gagactgttagaaaaaatcttgaagacagtgatgcaagtgtggaaagaagccagtatcct
caatcagatgataagctgtctcctcctaaacgcgacttccccactgcagaggaaccacac
ctgaatttgggttctttgaatgattctttatttggtagtgacaatattaaaatagaatca
ttgattacaaagaagactgtggatcacacagttgaagaacaacaaacagaaaaagttaaa
ttgatcacagaaaatctcagtaagctccctaatgcagactctgaatgcctttcttttgtt
ggctgttcaacatcaggaacaaattctggaaatggaacaaatggtttattagaaggatca
ccaccatccccattctttaagtttcaaggagaaatgattgtaaatgacttgtatgttcca
tcatcaccaatcctagcacctgtgagaagtcgtagcaagttggtttcaagaccatctcga
tcttttctgctaagacatcgacctgtaccagagattccagggtcaacaaaaggagtttct
gggagctatttccgtgaaagaagaaatgttgctacctcaactgaaaaatctgtggcatgg
caaaattcaaatgaggagaattcatcttccatctttccttatggagagacctttctcttc
cagagactagaaaattccaagaagcgatctataaagaatgaatttttgacccagggagaa
gcactcaaaggggaagcagctactgcaacaaactcttttatcatcaaatcaagcatatac
gataacagaaaggagaaaataagcgaggacaaggtggaagatatttggatacctcgagag
gacaaaaacaattttttgatagacactgcttctgaatcagaatactcaacagtagaagaa
tgctttcagagtttaagaagaaaaaattcaaaggcatctaaatctaggactcaaaaagcc
ttgattttggactccgttaataggcacagttatccgttaagctcaacaagtggaaatgct
gattcatcagccgtttcttcacaggcaatatctccctatgcctgcttttatggagcatct
gcaaagaaggttaaatcaggatggctggataaactctctcctcaaggaaaacgcatgttt
caaaagagatgggtgaaatttgatggccttagcatttcttactacaataatgagaaggag
atgtattcgaaaggaataattcccctttctgctatatcaacagtacgagttcaaggagac
aacaaatttgaagttgttacaacacaaagaacttttgtttttagagtagaaaaagaagag
gagagaaatgactggatcagcatactattaaatgcactgaaatcacaatcccttacctcg
cagtctcaagctgttgttacacctgagaaatgtggatatcttgaattgagaggctataag
gcaaaaatttttactgtgttaagtggaaacagtgtgtggctttgcaaaaacgaacaggat
tttaagagtggacttggtattaccataattcctatgaatgtagcaaatgtaaagcaagtg
gaccgaactgtgaaacaatcttttgaaataatcactccctacaggagtttcagctttaca
gccgagactgaaaaggagaaacaagactggattgaagctgtgcagcaatcaatagcagaa
actctctctgattatgaagtagctgagaagatttggttcaatgaatccaacaggagctgt
gcagattgtaaagccccagatcctgactgggcatccatcaatctctgtgttgtcatctgt
aagaagtgtgcaggacagcatagatctttaggaccaaaagattccaaggttagaagtcta
aaaatggatgctagcatttggagcaatgaactcatcgagctttttattgtcattggaaac
aaaagagcaaatgacttttgggctggtaatcttcaaaaggatgaagaattacatatggac
tcaccagtagaaaagagaaaaaactttattactcagaaatataaagaaggaaaattcaga
aaaactcttttggcatctctcaccaaagaagaattaaataaggctctatgtgctgctgta
gtgaaaccggatgttctagaaacaatggctttgctgttcagtggagcagatgtcatgtgt
gccaccggagaccccgtgcatagcaccccctatctgctagccaagaaagctgggcaaagt
ctgcaaatggaatttctctaccataacaaattctcagatttccctcaacatgatattcat
tccgagggtgtattaagtcaagagtcttcccagtccacattcctctgtgactttttatat
caagctccttctgctgcttctaaactctcttcagagaaaaaactgcttgaagagacaaat
aaaaaatggtgtgttttggaaggaggcttcttgagttactatgaaaatgataagtctacc
acacctaatggcaccattaatatcaatgaagttatctgcctggctatacacaaagaggac
ttctatttaaatactgggcccatctttatctttgagatctacttaccctccgaacgtgtg
tttttatttggagctgaaacatctcaagctcaaagaaaatggacagaggcaatagccaag
cattttgttcccttatttgctgaaaacttaacagaagctgactatgatttgattggtcaa
ctcttctacaaagactgccatgccctggatcagtggagaaaaggctggtttgctatggac
aaatccagcttgcatttttgccttcaaatgcaagaagttcagggagatagaatgcactta
agaagactgcaagagctaacaatcagcacaatggttcaaaatggggaaaaactggatgtt
ttactcttggtagaaaaagggagaacattatacatccatgggcataccaagttggatttc
acagtctggcatactgcaattgaaaaagcagcaggtacagatggtaatgctttacaagat
cagcagctcagcaaaaatgacgttcccattatagtgaacagctgtatagcatttgttaca
cagtatggtttaggatgcaaatatatctatcaaaagaatggtgatcctttgcatataagt
gaactcctggagagtttcaaaaaggatgcaagaagctttaaattgagggctggaaaacat
cagcttgaagatgtgacggctgtgttgaaaagttttctctctgacattgatgatgcactg
cttactaaggagctctacccatattggatctctgctttagatacgcaagatgacaaggaa
agaattaaaaaatatggagcatttatacgttctcttccaggggtcaaccgagcaacacta
gcagctatcattgaacacctgtatagggttcagaaatgctcagaaatcaatcacatgaat
gcccataatttggccttggtcttttcatcctgtttgtttcaaacgaagggacaaactagt
gaagaagtgaatgtaattgaggacctaattaataattatgtagaaatatttgaggttaaa
gaagatcaagtcaaacaaatggacatagaaaatagctttattaccaagtggaaagacacc
caagtttcccaggctggagatttgttaattgaagtatatgtagaaaggaaggaacccgac
tgtagtattataattcggatatctcctgtgatggaagcagaagaattaactaatgatata
ttagcgataaaaaatattattcctacaaaaggtgatatttgggccacatttgaagtcatt
gaaaatgaagagctagagcgtcctcttcactacaaggaaaatgtactggagcaggtgctt
cggtggagttcattagctgaacctggctctgcttacctggtggtgaagagattcttaacc
gctgacacaattaaacactgcagtgaccggagtacactgggaagcatcaaagaaggaatc
ttgaaaatcaaagaagaaccatccaaaatactatctggaaataagtttcaagaccggtat
tttgttttacgagatgggtttctctttctttacaaggatgtgaagagtagtaaacatgac
aagatgttttctctcagttccatgaagttttatcgtggagtgaaaaagaaaatgaagcct
ccaacaagctggggattgaccgcatattctgagaaacatcactggcacctgtgttgtgat
agttcacgaactcagacggagtggatgaccagtatctttattgcccagcatgaatatgat
atatggccaccagctggaaaggaacgaaaacgttcaataaccaaaaatcccaaaattgga
ggtttgcctctgattcctatacagcatgaggggaatgcaaccttggcccggaaaaatatt
gagagtgcaagagcagaacttgaaaggctgcggctcagtgaaaagtgtgataaagagtcc
gtggactctagcttaaaggagagagcttccatggtggcccactgcctggagcacaaggac
gataaacttcgaaatcgaccccgaaaacatcggagtttcaactgcctggaggacacagag
cctgaagccccacttgggcaaccaaaaggccataaaggcctaaagacattgaggaagact
gaggacaggaatagcaaagctactttggactctgatcataagttaccatcaagggtaatt
gaagaacttaatgtggttctacaacggtcaagaacccttccaaaagaattacaggatgag
cagattttgaagtag

All links

Ontology (2)   
   KEGG BRITE (2)   
Pathway (1)   
   KEGG PATHWAY (1)   
Disease (1)   
   OMIM (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (17)   
   KEGG ORTHOLOGY (1)   
   RefGene (6)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   UniGene (3)   
   HGNC (1)   
   Ensembl (1)   
   OC (1)   
   PHAROS (1)   
   VEGA (1)   
Protein sequence (8)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (5)   
DNA sequence (55)   
   RefSeq(nuc) (27)   
   GenBank (14)   
   EMBL (14)   
Protein domain (12)   
   Pfam (12)   
All databases (97)   

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