KEGG T01001: 128239

Homo sapiens (human): 128239

Entry

128239 CDS T01001

Gene name

IQGAP3

Definition

IQ motif containing GTPase activating protein 3

Orthology

K05767

Ras GTPase-activating-like protein IQGAP2/3

Organism

hsa Homo sapiens (human)

Pathway

hsa04810

Regulation of actin cytoskeleton

Class

Cellular Processes; Cell motility; Regulation of actin cytoskeleton [PATH:hsa04810]

SSDB

Motif

Pfam:

RasGAP RasGAP_C IQ CH CAMSAP_CH AsnA SHD1 WW

Other DBs

NCBI-GI:

NCBI-GeneID:

HGNC:

HPRD:

Ensembl:

Vega:

UniProt:

Structure

PDB:

3ISU

Position

1q21.3

AA seq 1631 aa
MERRAAGPGWAAYERLTAEEMDEQRRQNVAYQYLCRLEEAKRWMEACLKEELPSPVELEE
SLRNGVLLAKLGHCFAPSVVPLKKIYDVEQLRYQATGLHFRHTDNINFWLSAIAHIGLPS
TFFPETTDIYDKKNMPRVVYCIHALSLFLFRLGLAPQIHDLYGKVKFTAEELSNMASELA
KYGLQLPAFSKIGGILANELSVDEAAVHAAVLAINEAVERGVVEDTLAALQNPSALLENL
REPLAAVYQEMLAQAKMEKAANARNHDDRESQDIYDHYLTQAEIQGNINHVNVHGALEVV
DDALERQSPEALLKALQDPALALRGVRRDFADWYLEQLNSDREQKAQELGLVELLEKEEV
QAGVAAANTKGDQEQAMLHAVQRINKAIRRGVAADTVKELMCPEAQLPPVYPVASSMYQL
ELAVLQQQQGELGQEELFVAVEMLSAVVLINRALEARDASGFWSSLVNPATGLAEVEGEN
AQRYFDALLKLRQERGMGEDFLSWNDLQATVSQVNAQTQEETDRVLAVSLINEALDKGSP
EKTLSALLLPAAGLDDVSLPVAPRYHLLLVAAKRQKAQVTGDPGAVLWLEEIRQGVVRAN
QDTNTAQRMALGVAAINQAIKEGKAAQTERVLRNPAVALRGVVPDCANGYQRALESAMAK
KQRPADTAFWVQHDMKDGTAYYFHLQTFQGIWEQPPGCPLNTSHLTREEIQSAVTKVTAA
YDRQQLWKANVGFVIQLQARLRGFLVRQKFAEHSHFLRTWLPAVIKIQAHWRGYRQRKIY
LEWLQYFKANLDAIIKIQAWARMWAARRQYLRRLHYFQKNVNSIVKIQAFFRARKAQDDY
RILVHAPHPPLSVVRRFAHLLNQSQQDFLAEAELLKLQEEVVRKIRSNQQLEQDLNIMDI
KIGLLVKNRITLQEVVSHCKKLTKRNKEQLSDMMVLDKQKGLKSLSKEKRQKLEAYQHLF
YLLQTQPIYLAKLIFQMPQNKTTKFMEAVIFSLYNYASSRREAYLLLQLFKTALQEEIKS
KVEQPQDVVTGNPTVVRLVVRFYRNGRGQSALQEILGKVIQDVLEDKVLSVHTDPVHLYK
NWINQTEAQTGQRSHLPYDVTPEQALSHPEVQRRLDIALRNLLAMTDKFLLAITSSVDQI
PYGMRYVAKVLKATLAEKFPDATDSEVYKVVGNLLYYRFLNPAVVAPDAFDIVAMAAGGA
LAAPQRHALGAVAQLLQHAAAGKAFSGQSQHLRVLNDYLEETHLKFRKFIHRACQVPEPE
ERFAVDEYSDMVAVAKPMVYITVGELVNTHRLLLEHQDCIAPDHQDPLHELLEDLGELPT
IPDLIGESIAADGHTDLSKLEVSLTLTNKFEGLEADADDSNTRSLLLSTKQLLADIIQFH
PGDTLKEILSLSASREQEAAHKQLMSRRQACTAQTPEPLRRHRSLTAHSLLPLAEKQRRV
LRNLRRLEALGLVSARNGYQGLVDELAKDIRNQHRHRHRRKAELVKLQATLQGLSTKTTF
YEEQGDYYSQYIRACLDHLAPDSKSSGKGKKQPSLHYTAAQLLEKGVLVEIEDLPASHFR
NVIFDITPGDEAGKFEVNAKFLGVDMERFQLHYQDLLQLQYEGVAVMKLFNKAKVNVNLL
IFLLNKKFLRK

NT seq 4896 nt +upstreamnt +downstreamnt
atggagaggagagcagcgggcccaggctgggcagcctatgaacgcctcacagctgaggag
atggatgagcagaggcggcagaatgttgcctatcagtacctgtgccggctggaggaggcc
aagcgctggatggaggcctgcctgaaggaggagcttccttccccggtggagctggaggag
agccttcggaatggagtgctgctggccaagctaggccactgttttgcaccctccgtggtt
cccttgaagaagatctacgatgtggagcagctgcggtaccaggcaactggcttacatttc
cgtcacacagacaacatcaacttttggctatctgcaatagcccacatcggtctgccttcg
accttcttcccagagaccacggacatctatgacaaaaagaacatgccccgggtagtctac
tgcatccatgctctcagtctcttcctcttccggctgggattggcccctcagatacatgat
ctatacgggaaagtgaaattcacagctgaggaactcagcaacatggcgtccgaactggcc
aaatatggcctccagctgcctgccttcagcaagatcgggggcatcttggccaatgagctc
tcggtggatgaggctgcagtccatgcagctgttcttgccatcaatgaagcagtggagcga
ggggtggtggaggacaccctggctgccttgcagaatcccagtgctcttctggagaatctc
cgagagcctctggcagccgtctaccaagagatgctggcccaggccaagatggagaaggca
gccaatgccaggaaccatgatgacagagaaagccaggacatctatgaccactacctaact
caggctgaaatccagggcaatatcaaccatgtcaacgtccatggggctctagaagttgtt
gatgatgccctggaaagacagagccctgaagccttgctcaaggcccttcaagaccctgcc
ctggccctgcgaggggtgaggagagactttgctgactggtacctggagcagctgaactca
gacagagagcagaaggcacaggagctgggcctggtggagcttctggaaaaggaggaagtc
caggctggtgtggctgcagccaacacaaagggtgatcaggaacaagccatgctccacgct
gtgcagcggatcaacaaagccatccggaggggagtggcggctgacactgtgaaggagctg
atgtgccctgaggcccagctgcctccagtgtaccctgttgcatcgtctatgtaccagctg
gagctggcagtgctccagcagcagcagggggagcttggccaggaggagctcttcgtggct
gtggagatgctctcagctgtggtcctgattaaccgggccctggaggcccgggatgccagt
ggcttctggagcagcctggtgaaccctgccacaggcctggctgaggtggaaggagaaaat
gcccagcgttacttcgatgccctgctgaaattgcgacaggagcgtgggatgggtgaggac
ttcctgagctggaatgacctgcaggccaccgtgagccaggtcaatgcacagacccaggaa
gagactgaccgggtccttgcagtcagcctcatcaatgaggctctggacaaaggcagccct
gagaagactctgtctgccctactgcttcctgcagctggcctagatgatgtcagcctccct
gtcgcccctcggtaccatctcctccttgtggcagccaaaaggcagaaggcccaggtgaca
ggggatcctggagctgtgctgtggcttgaggagatccgccagggagtggtcagagccaac
caggacactaatacagctcagagaatggctcttggtgtggctgccatcaatcaagccatc
aaggagggcaaggcagcccagactgagcgggtgttgaggaaccccgcagtggcccttcga
ggggtagttcccgactgtgccaacggctaccagcgagccctggaaagtgccatggcaaag
aaacagcgtccagcagacacagctttctgggttcaacatgacatgaaggatggcactgcc
tactacttccatctgcagaccttccaggggatctgggagcaacctcctggctgccccctc
aacacctctcacctgacccgggaggagatccagtcagctgtcaccaaggtcactgctgcc
tatgaccgccaacagctctggaaagccaacgtcggctttgttatccagctccaggcccgc
ctccgtggcttcctagttcggcagaagtttgctgagcattcccactttctgaggacctgg
ctcccagcagtcatcaagatccaggctcattggcggggttataggcagcggaagatttac
ctggagtggttgcagtattttaaagcaaacctggatgccataatcaagatccaggcctgg
gcccggatgtgggcagctcggaggcaatacctgaggcgtctgcactacttccagaagaat
gttaactccattgtgaagatccaggcatttttccgagccaggaaagcccaagatgactac
aggatattagtgcatgcaccccaccctcctctcagtgtggtacgcagatttgcccatctc
ttgaatcaaagccagcaagacttcttggctgaggcagagctgctgaagctccaggaagag
gtagttaggaagatccgatccaatcagcagctggagcaggacctcaacatcatggacatc
aagattggcctgctggtgaagaaccggatcactctgcaggaagtggtctcccactgcaag
aagctgaccaagaggaataaggaacagctgtcagatatgatggttctggacaagcagaag
ggtttaaagtcgctgagcaaagagaaacggcagaaactagaagcataccaacacctcttc
tacctgctccagactcagcccatctacctggccaagctgatctttcagatgccacagaac
aaaaccaccaagttcatggaggcagtgattttcagcctgtacaactatgcctccagccgc
cgagaggcctatctcctgctccagctgttcaagacagcactccaggaggaaatcaagtca
aaggtggagcagccccaggacgtggtgacaggcaacccaacagtggtgaggctggtggtg
agattctaccgtaatgggcggggacagagtgccctgcaggagattctgggcaaggttatc
caggatgtgctagaagacaaagtgctcagcgtccacacagaccctgtccacctctataag
aactggatcaaccagactgaggcccagacagggcagcgcagccatctcccatatgatgtc
accccggagcaggccttgagccaccccgaggtccagagacgactggacatcgccctacgc
aacctcctcgccatgactgataagttccttttagccatcacctcatctgtggaccaaatt
ccgtatgggatgcgatatgtggccaaagtcctgaaggcaactctggcagagaaattccct
gacgccacagacagcgaggtctataaggtggtcgggaacctcctgtactaccgcttcctg
aacccagctgtggtggctcctgacgccttcgacattgtggccatggcagctggtggagcc
ctggctgccccccagcgccatgccctgggggctgtggctcagctcctacagcacgctgcg
gctggcaaggccttctctgggcagagccagcacctacgggtcctgaatgactatctggag
gaaacacacctcaagttcaggaagttcatccatagagcctgccaggtgccagagccagag
gagcgttttgcagtggacgagtactcagacatggtggctgtggccaaacccatggtgtac
atcaccgtgggggagctggtcaacacgcacaggctgttgctggagcaccaggactgcatt
gcccctgatcaccaagaccccctgcatgagctcctggaggatcttggggagctgcccacc
atccctgaccttattggtgagagcatcgctgcagatgggcacacggacctgagcaagcta
gaagtgtccctgacgctgaccaacaagtttgaaggactagaggcagatgctgatgactcc
aacacccgtagcctgcttctgagcaccaagcagctgttggccgatatcatacagttccat
cctggggacaccctcaaggagatcctgtccctctcggcttccagagagcaagaagcagcc
cacaagcagctgatgagccgacgccaggcctgtacagcccagacaccggagccactgcga
cgacaccgctcactgacagctcactccctcctgccactggcagagaagcagcggcgcgtc
ctgcggaacctacgccgacttgaagccctggggttggtcagcgccagaaatggctaccag
gggctagtggacgagctggccaaggacatccgcaaccagcacagacacaggcacaggcgg
aaggcagagctggtgaagctgcaggccacattacagggcctgagcactaagaccaccttc
tatgaggagcagggtgactactacagccagtacatccgggcctgcctggaccacctggcc
cccgactccaagagttctgggaaggggaagaagcagccttctcttcattacactgctgct
cagctcctggaaaagggtgtcttggtggaaattgaagatcttcccgcctctcacttcaga
aacgtcatctttgacatcacgccgggagatgaggcaggaaagtttgaagtaaatgccaag
ttcctgggtgtggacatggagcgatttcagcttcactatcaggatctcctgcagctccag
tatgagggtgtggctgtcatgaaactcttcaacaaggccaaagtcaatgtcaaccttctc
atcttcctcctcaacaagaagtttttgcggaagtga

All links

Pathway (1)   
   KEGG PATHWAY (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (13)   
   KEGG ORTHOLOGY (1)   
   NCBI-Gene (1)   
   NCBI-GI (5)   
   UniGene (1)   
   HGNC (1)   
   HPRD (1)   
   ENSEMBL-HSA (1)   
   OC (1)   
   VEGA (1)   
Protein sequence (2)   
   UniProt (1)   
   RefSeq(pep) (1)   
DNA sequence (15)   
   RefSeq(nuc) (1)   
   GenBank (7)   
   EMBL (7)   
3D Structure (1)   
   PDB (1)   
Protein domain (8)   
   Pfam (8)   
All databases (41)   

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