KEGG   Homo sapiens (human): 128239
Entry
128239            CDS       T01001                                 
Symbol
IQGAP3
Name
(RefSeq) IQ motif containing GTPase activating protein 3
  KO
K05767  Ras GTPase-activating-like protein IQGAP2/3
Organism
hsa  Homo sapiens (human)
Pathway
hsa04810  Regulation of actin cytoskeleton
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09140 Cellular Processes
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    128239 (IQGAP3)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04812 Cytoskeleton proteins [BR:hsa04812]
    128239 (IQGAP3)
   04147 Exosome [BR:hsa04147]
    128239 (IQGAP3)
Cytoskeleton proteins [BR:hsa04812]
 Eukaryotic cytoskeleton proteins
  Actin filaments / Microfilaments
   Actin-binding proteins
    Others
     128239 (IQGAP3)
Exosome [BR:hsa04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   128239 (IQGAP3)
  Exosomal proteins of colorectal cancer cells
   128239 (IQGAP3)
SSDB
Motif
Pfam: RasGAP RasGAP_C CH IQ SHD1 CAMSAP_CH
Other DBs
NCBI-GeneID: 128239
NCBI-ProteinID: NP_839943
HGNC: 20669
Ensembl: ENSG00000183856
UniProt: Q86VI3
Structure
Position
1:complement(156525405..156572565)
AA seq 1631 aa
MERRAAGPGWAAYERLTAEEMDEQRRQNVAYQYLCRLEEAKRWMEACLKEELPSPVELEE
SLRNGVLLAKLGHCFAPSVVPLKKIYDVEQLRYQATGLHFRHTDNINFWLSAIAHIGLPS
TFFPETTDIYDKKNMPRVVYCIHALSLFLFRLGLAPQIHDLYGKVKFTAEELSNMASELA
KYGLQLPAFSKIGGILANELSVDEAAVHAAVLAINEAVERGVVEDTLAALQNPSALLENL
REPLAAVYQEMLAQAKMEKAANARNHDDRESQDIYDHYLTQAEIQGNINHVNVHGALEVV
DDALERQSPEALLKALQDPALALRGVRRDFADWYLEQLNSDREQKAQELGLVELLEKEEV
QAGVAAANTKGDQEQAMLHAVQRINKAIRRRVAADTVKELMCPEAQLPPVYPVASSMYQL
ELAVLQQQQGELGQEELFVAVEMLSAVVLINRALEARDASGFWSSLVNPATGLAEVEGEN
AQRYFDALLKLRQERGMGEDFLSWNDLQATVSQVNAQTQEETDRVLAVSLINEALDKGSP
EKTLSALLLPAAGLDDVSLPVAPRYHLLLVAAKRQKAQVTGDPGAVLWLEEIRQGVVRAN
QDTNTAQRMALGVAAINQAIKEGKAAQTERVLRNPAVALRGVVPDCANGYQRALESAMAK
KQRPADTAFWVQHDMKDGTAYYFHLQTFQGIWEQPPGCPLNTSHLTREEIQSAVTKVTAA
YDRQQLWKANVGFVIQLQARLRGFLVRQKFAEHSHFLRTWLPAVIKIQAHWRGYRQRKIY
LEWLQYFKANLDAIIKIQAWARMWAARRQYLRRLHYFQKNVNSIVKIQAFFRARKAQDDY
RILVHAPHPPLSVVRRFAHLLNQSQQDFLAEAELLKLQEEVVRKIRSNQQLEQDLNIMDI
KIGLLVKNRITLQEVVSHCKKLTKRNKEQLSDMMVLDKQKGLKSLSKEKRQKLEAYQHLF
YLLQTQPIYLAKLIFQMPQNKTTKFMEAVIFSLYNYASSRREAYLLLQLFKTALQEEIKS
KVEQPQDVVTGNPTVVRLVVRFYRNGRGQSALQEILGKVIQDVLEDKVLSVHTDPVHLYK
NWINQTEAQTGQRSHLPYDVTPEQALSHPEVQRRLDIALRNLLAMTDKFLLAITSSVDQI
PYGMRYVAKVLKATLAEKFPDATDSEVYKVVGNLLYYRFLNPAVVAPDAFDIVAMAAGGA
LAAPQRHALGAVAQLLQHAAAGKAFSGQSQHLRVLNDYLEETHLKFRKFIHRACQVPEPE
ERFAVDEYSDMVAVAKPMVYITVGELVNTHRLLLEHQDCIAPDHQDPLHELLEDLGELPT
IPDLIGESIAADGHTDLSKLEVSLTLTNKFEGLEADADDSNTRSLLLSTKQLLADIIQFH
PGDTLKEILSLSASREQEAAHKQLMSRRQACTAQTPEPLRRHRSLTAHSLLPLAEKQRRV
LRNLRRLEALGLVSARNGYQGLVDELAKDIRNQHRHRHRRKAELVKLQATLQGLSTKTTF
YEEQGDYYSQYIRACLDHLAPDSKSSGKGKKQPSLHYTAAQLLEKGVLVEIEDLPASHFR
NVIFDITPGDEAGKFEVNAKFLGVDMERFQLHYQDLLQLQYEGVAVMKLFNKAKVNVNLL
IFLLNKKFLRK
NT seq 4896 nt   +upstreamnt  +downstreamnt
atggagaggagagcagcgggcccaggctgggcagcctatgaacgcctcacagctgaggag
atggatgagcagaggcggcagaatgttgcctatcagtacctgtgccggctggaggaggcc
aagcgctggatggaggcctgcctgaaggaggagcttccttccccggtggagctggaggag
agccttcggaatggagtgctgctggccaagctaggccactgttttgcaccctccgtggtt
cccttgaagaagatctacgatgtggagcagctgcggtaccaggcaactggcttacatttc
cgtcacacagacaacatcaacttttggctatctgcaatagcccacatcggtctgccttcg
accttcttcccagagaccacggacatctatgacaaaaagaacatgccccgggtagtctac
tgcatccatgctctcagtctcttcctcttccggctgggattggcccctcagatacatgat
ctatacgggaaagtgaaattcacagctgaggaactcagcaacatggcgtccgaactggcc
aaatatggcctccagctgcctgccttcagcaagatcgggggcatcttggccaatgagctc
tcggtggatgaggctgcagtccatgcagctgttcttgccatcaatgaagcagtggagcga
ggggtggtggaggacaccctggctgccttgcagaatcccagtgctcttctggagaatctc
cgagagcctctggcagccgtctaccaagagatgctggcccaggccaagatggagaaggca
gccaatgccaggaaccatgatgacagagaaagccaggacatctatgaccactacctaact
caggctgaaatccagggcaatatcaaccatgtcaacgtccatggggctctagaagttgtt
gatgatgccctggaaagacagagccctgaagccttgctcaaggcccttcaagaccctgcc
ctggccctgcgaggggtgaggagagactttgctgactggtacctggagcagctgaactca
gacagagagcagaaggcacaggagctgggcctggtggagcttctggaaaaggaggaagtc
caggctggtgtggctgcagccaacacaaagggtgatcaggaacaagccatgctccacgct
gtgcagcggatcaacaaagccatccggaggagagtggcggctgacactgtgaaggagctg
atgtgccctgaggcccagctgcctccagtgtaccctgttgcatcgtctatgtaccagctg
gagctggcagtgctccagcagcagcagggggagcttggccaggaggagctcttcgtggct
gtggagatgctctcagctgtggtcctgattaaccgggccctggaggcccgggatgccagt
ggcttctggagcagcctggtgaaccctgccacaggcctggctgaggtggaaggagaaaat
gcccagcgttacttcgatgccctgctgaaattgcgacaggagcgtgggatgggtgaggac
ttcctgagctggaatgacctgcaggccaccgtgagccaggtcaatgcacagacccaggaa
gagactgaccgggtccttgcagtcagcctcatcaatgaggctctggacaaaggcagccct
gagaagactctgtctgccctactgcttcctgcagctggcctagatgatgtcagcctccct
gtcgcccctcggtaccatctcctccttgtggcagccaaaaggcagaaggcccaggtgaca
ggggatcctggagctgtgctgtggcttgaggagatccgccagggagtggtcagagccaac
caggacactaatacagctcagagaatggctcttggtgtggctgccatcaatcaagccatc
aaggagggcaaggcagcccagactgagcgggtgttgaggaaccccgcagtggcccttcga
ggggtagttcccgactgtgccaacggctaccagcgagccctggaaagtgccatggcaaag
aaacagcgtccagcagacacagctttctgggttcaacatgacatgaaggatggcactgcc
tactacttccatctgcagaccttccaggggatctgggagcaacctcctggctgccccctc
aacacctctcacctgacccgggaggagatccagtcagctgtcaccaaggtcactgctgcc
tatgaccgccaacagctctggaaagccaacgtcggctttgttatccagctccaggcccgc
ctccgtggcttcctagttcggcagaagtttgctgagcattcccactttctgaggacctgg
ctcccagcagtcatcaagatccaggctcattggcggggttataggcagcggaagatttac
ctggagtggttgcagtattttaaagcaaacctggatgccataatcaagatccaggcctgg
gcccggatgtgggcagctcggaggcaatacctgaggcgtctgcactacttccagaagaat
gttaactccattgtgaagatccaggcatttttccgagccaggaaagcccaagatgactac
aggatattagtgcatgcaccccaccctcctctcagtgtggtacgcagatttgcccatctc
ttgaatcaaagccagcaagacttcttggctgaggcagagctgctgaagctccaggaagag
gtagttaggaagatccgatccaatcagcagctggagcaggacctcaacatcatggacatc
aagattggcctgctggtgaagaaccggatcactctgcaggaagtggtctcccactgcaag
aagctgaccaagaggaataaggaacagctgtcagatatgatggttctggacaagcagaag
ggtttaaagtcgctgagcaaagagaaacggcagaaactagaagcataccaacacctcttc
tacctgctccagactcagcccatctacctggccaagctgatctttcagatgccacagaac
aaaaccaccaagttcatggaggcagtgattttcagcctgtacaactatgcctccagccgc
cgagaggcctatctcctgctccagctgttcaagacagcactccaggaggaaatcaagtca
aaggtggagcagccccaggacgtggtgacaggcaacccaacagtggtgaggctggtggtg
agattctaccgtaatgggcggggacagagtgccctgcaggagattctgggcaaggttatc
caggatgtgctagaagacaaagtgctcagcgtccacacagaccctgtccacctctataag
aactggatcaaccagactgaggcccagacagggcagcgcagccatctcccatatgatgtc
accccggagcaggccttgagccaccccgaggtccagagacgactggacatcgccctacgc
aacctcctcgccatgactgataagttccttttagccatcacctcatctgtggaccaaatt
ccgtatgggatgcgatatgtggccaaagtcctgaaggcaactctggcagagaaattccct
gacgccacagacagcgaggtctataaggtggtcgggaacctcctgtactaccgcttcctg
aacccagctgtggtggctcctgacgccttcgacattgtggccatggcagctggtggagcc
ctggctgccccccagcgccatgccctgggggctgtggctcagctcctacagcacgctgcg
gctggcaaggccttctctgggcagagccagcacctacgggtcctgaatgactatctggag
gaaacacacctcaagttcaggaagttcatccatagagcctgccaggtgccagagccagag
gagcgttttgcagtggacgagtactcagacatggtggctgtggccaaacccatggtgtac
atcaccgtgggggagctggtcaacacgcacaggctgttgctggagcaccaggactgcatt
gcccctgatcaccaagaccccctgcatgagctcctggaggatcttggggagctgcccacc
atccctgaccttattggtgagagcatcgctgcagatgggcacacggacctgagcaagcta
gaagtgtccctgacgctgaccaacaagtttgaaggactagaggcagatgctgatgactcc
aacacccgtagcctgcttctgagcaccaagcagctgttggccgatatcatacagttccat
cctggggacaccctcaaggagatcctgtccctctcggcttccagagagcaagaagcagcc
cacaagcagctgatgagccgacgccaggcctgtacagcccagacaccggagccactgcga
cgacaccgctcactgacagctcactccctcctgccactggcagagaagcagcggcgcgtc
ctgcggaacctacgccgacttgaagccctggggttggtcagcgccagaaatggctaccag
gggctagtggacgagctggccaaggacatccgcaaccagcacagacacaggcacaggcgg
aaggcagagctggtgaagctgcaggccacattacagggcctgagcactaagaccaccttc
tatgaggagcagggtgactactacagccagtacatccgggcctgcctggaccacctggcc
cccgactccaagagttctgggaaggggaagaagcagccttctcttcattacactgctgct
cagctcctggaaaagggtgtcttggtggaaattgaagatcttcccgcctctcacttcaga
aacgtcatctttgacatcacgccgggagatgaggcaggaaagtttgaagtaaatgccaag
ttcctgggtgtggacatggagcgatttcagcttcactatcaggatctcctgcagctccag
tatgagggtgtggctgtcatgaaactcttcaacaaggccaaagtcaatgtcaaccttctc
atcttcctcctcaacaagaagtttttgcggaagtga

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (1)   
   KEGG PATHWAY (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (19)   
   KEGG ORTHOLOGY (1)   
   RefGene (12)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (1)   
   OC (1)   
Protein sequence (24)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (22)   
DNA sequence (36)   
   RefSeq(nuc) (22)   
   GenBank (7)   
   EMBL (7)   
3D Structure (1)   
   PDB (1)   
Protein domain (6)   
   Pfam (6)   
All databases (91)   

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