KEGG   Homo sapiens (human): 1495
Entry
1495              CDS       T01001                                 
Symbol
CTNNA1, CAP102, MDBS2, MDPT2
Name
(RefSeq) catenin alpha 1
  KO
K05691  catenin alpha
Organism
hsa  Homo sapiens (human)
Pathway
hsa04390  Hippo signaling pathway
hsa04520  Adherens junction
hsa04670  Leukocyte transendothelial migration
hsa05100  Bacterial invasion of epithelial cells
hsa05200  Pathways in cancer
hsa05213  Endometrial cancer
hsa05226  Gastric cancer
hsa05412  Arrhythmogenic right ventricular cardiomyopathy
Disease
H01890  Pattern dystrophies of the retinal pigment epithelium
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04390 Hippo signaling pathway
    1495 (CTNNA1)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04520 Adherens junction
    1495 (CTNNA1)
 09150 Organismal Systems
  09151 Immune system
   04670 Leukocyte transendothelial migration
    1495 (CTNNA1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    1495 (CTNNA1)
  09162 Cancer: specific types
   05226 Gastric cancer
    1495 (CTNNA1)
   05213 Endometrial cancer
    1495 (CTNNA1)
  09171 Infectious disease: bacterial
   05100 Bacterial invasion of epithelial cells
    1495 (CTNNA1)
  09166 Cardiovascular disease
   05412 Arrhythmogenic right ventricular cardiomyopathy
    1495 (CTNNA1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04812 Cytoskeleton proteins [BR:hsa04812]
    1495 (CTNNA1)
Cytoskeleton proteins [BR:hsa04812]
 Eukaryotic cytoskeleton proteins
  Actin filaments / Microfilaments
   Actin-binding proteins
    Cross-linking proteins
     1495 (CTNNA1)
SSDB
Motif
Pfam: Vinculin Peptidase_C5 GIT1_C I_LWEQ
Other DBs
NCBI-GeneID: 1495
NCBI-ProteinID: NP_001310911
OMIM: 116805
HGNC: 2509
Ensembl: ENSG00000044115
UniProt: P35221 A0A384MDY0
Structure
Position
5:138753425..138935034
AA seq 906 aa
MTAVHAGNINFKWDPKSLEIRTLAVERLLEPLVTQVTTLVNTNSKGPSNKKRGRSKKAHV
LAASVEQATENFLEKGDKIAKESQFLKEELVAAVEDVRKQGDLMKAAAGEFADDPCSSVK
RGNMVRAARALLSAVTRLLILADMADVYKLLVQLKVVEDGILKLRNAGNEQDLGIQYKAL
KPEVDKLNIMAAKRQQELKDVGHRDQMAAARGILQKNVPILYTASQACLQHPDVAAYKAN
RDLIYKQLQQAVTGISNAAQATASDDASQHQGGGGGELAYALNNFDKQIIVDPLSFSEER
FRPSLEERLESIISGAALMADSSCTRDDRRERIVAECNAVRQALQDLLSEYMGNAGRKER
SDALNSAIDKMTKKTRDLRRQLRKAVMDHVSDSFLETNVPLLVLIEAAKNGNEKEVKEYA
QVFREHANKLIEVANLACSISNNEEGVKLVRMSASQLEALCPQVINAALALAAKPQSKLA
QENMDLFKEQWEKQVRVLTDAVDDITSIDDFLAVSENHILEDVNKCVIALQEKDVDGLDR
TAGAIRGRAARVIHVVTSEMDNYEPGVYTEKVLEATKLLSNTVMPRFTEQVEAAVEALSS
DPAQPMDENEFIDASRLVYDGIRDIRKAVLMIRTPEELDDSDFETEDFDVRSRTSVQTED
DQLIAGQSARAIMAQLPQEQKAKIAEQVASFQEEKSKLDAEVSKWDDSGNDIIVLAKQMC
MIMMEMTDFTRGKGPLKNTSDVISAAKKIAEAGSRMDKLGRTIADHCPDSACKQDLLAYL
QRIALYCHQLNICSKVKAEVQNLGGELVVSGVDSAMSLIQAAKNLMNAVVQTVKASYVAS
TKYQKSQGMASLNLPAVSWKMKAPEKKPLVKREKQDETQTKIKRASQKKHVNPVQALSEF
KAMDSI
NT seq 2721 nt   +upstreamnt  +downstreamnt
atgactgctgtccatgcaggcaacataaacttcaagtgggatcctaaaagtctagagatc
aggactctggcagttgagagactgttggagcctcttgttacacaggttacaacccttgta
aacaccaatagtaaagggccctctaataagaagagaggtcgttctaagaaggcccatgtt
ttggctgcatctgttgaacaagcaactgagaatttcttggagaagggggataaaattgcg
aaggagagccagtttctcaaggaggagcttgtggctgctgtagaagatgttcgaaaacaa
ggtgatttgatgaaggctgctgcaggagagttcgcagatgatccctgctcttctgtgaag
cgaggcaacatggttcgggcagctcgagctttgctctctgctgttacccggttgctgatt
ttggctgacatggcagatgtctacaaattacttgttcagctgaaagttgtggaagatggt
atcttgaagttgaggaatgctggcaatgaacaagacttaggaatccagtataaagcccta
aaacctgaagtggataagctgaacattatggcagccaaaagacaacaggaattgaaagat
gttggccatcgtgatcagatggctgcagctagaggaatcctgcagaagaacgttccgatc
ctctatactgcatcccaggcatgcctacagcaccctgatgtcgcagcctataaggccaac
agggacctgatatacaagcagctgcagcaggcggtcacaggcatttccaatgcagcccag
gccactgcctcagacgatgcctcacagcaccagggtggaggaggaggagaactggcatat
gcactcaataactttgacaaacaaatcattgtggaccccttgagcttcagcgaggagcgc
tttaggccttccctggaggagcgtctggaaagcatcattagtggggctgccttgatggcc
gactcgtcctgcacgcgtgatgaccgtcgtgagcgaattgtggcagagtgtaatgctgtc
cgccaggccctgcaggacctgctttcggagtacatgggcaatgctggacgtaaagaaaga
agtgatgcactcaattctgcaatagataaaatgaccaagaagaccagggacttgcgtaga
cagctccgcaaagctgtcatggaccacgtttcagattctttcctggaaaccaatgttcca
cttttggtattgattgaagctgcaaagaatggaaatgagaaagaagttaaggagtatgcc
caagttttccgtgaacatgccaacaaattgattgaggttgccaacttggcctgttccatc
tcaaataatgaagaaggtgtaaagcttgttcgaatgtctgcaagccagttagaagccctc
tgtcctcaggttattaatgctgcactggctttagcagcaaaaccacagagtaaactggcc
caagagaacatggatctttttaaagaacaatgggaaaaacaagtccgtgttctcacagat
gctgtcgatgacattacttccattgatgacttcttggctgtctcagagaatcacattttg
gaagatgtgaacaaatgtgtcattgctctccaagagaaggatgtggatggcctggaccgc
acagctggtgcaattcgaggccgggcagcccgggtcattcacgtagtcacctcagagatg
gacaactatgagccaggagtctacacagagaaggttctggaagccactaagctgctctcc
aacacagtcatgccacgttttactgagcaagtagaagcagccgtggaagccctcagctcg
gaccctgcccagcccatggatgagaatgagtttatcgatgcttcccgcctggtatatgat
ggcatccgggacatcaggaaagcagtgctgatgataaggacccctgaggagttggatgac
tctgactttgagacagaagattttgatgtcagaagcaggacgagcgtccagacagaagac
gatcagctgatagctggccagagtgcccgggcgatcatggctcagcttccccaggagcaa
aaagcgaagattgcggaacaggtggccagcttccaggaagaaaagagcaagctggatgct
gaagtgtccaaatgggacgacagtggcaatgacatcattgtgctggccaagcagatgtgc
atgattatgatggagatgacagactttacccgaggtaaaggaccactcaaaaatacatcg
gatgtcatcagtgctgccaagaaaattgctgaggcaggatccaggatggacaagcttggc
cgcaccattgcagaccattgccccgactcggcttgcaagcaggacctgctggcctacctg
caacgcatcgccctctactgccaccagctgaacatctgcagcaaggtcaaggccgaggtg
cagaatctcggcggggagcttgttgtctctggggtggacagcgccatgtccctgatccag
gcagccaagaacttgatgaatgctgtggtgcagacagtgaaggcatcctacgtcgcctct
accaaataccaaaagtcacagggtatggcttccctcaaccttcctgctgtgtcatggaag
atgaaggcaccagagaaaaagccattggtgaagagagagaaacaggatgagacacagacc
aagattaaacgggcatctcagaagaagcacgtgaacccggtgcaggccctcagcgagttc
aaagctatggacagcatctaa

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (8)   
   KEGG PATHWAY (8)   
Disease (3)   
   KEGG DISEASE (1)   
   OMIM (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (38)   
   KEGG ORTHOLOGY (1)   
   RefGene (11)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (21)   
   OC (1)   
Protein sequence (41)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (38)   
DNA sequence (78)   
   RefSeq(nuc) (38)   
   GenBank (20)   
   EMBL (20)   
3D Structure (7)   
   PDB (7)   
Protein domain (4)   
   Pfam (4)   
All databases (182)   

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