KEGG   Homo sapiens (human): 1544Help
Entry
1544              CDS       T01001                                 

Gene name
CYP1A2, CP12, P3-450, P450(PA)
Definition
cytochrome P450, family 1, subfamily A, polypeptide 2 (EC:1.14.14.1)
Orthology
K07409  
cytochrome P450, family 1, subfamily A, polypeptide 2 [EC:1.14.14.1]
Organism
hsa  Homo sapiens (human)
Pathway
Steroid hormone biosynthesis
Caffeine metabolism
Tryptophan metabolism
Linoleic acid metabolism
Retinol metabolism
Metabolism of xenobiotics by cytochrome P450
Drug metabolism - cytochrome P450
Metabolic pathways
Chemical carcinogenesis
Brite
KEGG Orthology (KO) [BR:hsa00001]
 Metabolism
  Lipid metabolism
   00140 Steroid hormone biosynthesis
    1544 (CYP1A2)
   00591 Linoleic acid metabolism
    1544 (CYP1A2)
  Amino acid metabolism
   00380 Tryptophan metabolism
    1544 (CYP1A2)
  Metabolism of cofactors and vitamins
   00830 Retinol metabolism
    1544 (CYP1A2)
  Biosynthesis of other secondary metabolites
   00232 Caffeine metabolism
    1544 (CYP1A2)
  Xenobiotics biodegradation and metabolism
   00980 Metabolism of xenobiotics by cytochrome P450
    1544 (CYP1A2)
   00982 Drug metabolism - cytochrome P450
    1544 (CYP1A2)
 Human Diseases
  Cancers
   05204 Chemical carcinogenesis
    1544 (CYP1A2)
Enzymes [BR:hsa01000]
 1. Oxidoreductases
  1.14  Acting on paired donors with incorporation of molecular oxygen
   1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.14.1  unspecific monooxygenase
     1544 (CYP1A2)
Cytochrome P450 [BR:hsa00199]
 Cytochrome P450, animal type
  CYP1 family
   1544 (CYP1A2)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: 
Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
OMIM: 
HGNC: 
HPRD: 
Ensembl: 
Vega: 
UniProt: 
Structure
PDB: 

Jmol
Position
15q24.1
AA seq 516 aa AA seqDB search
MALSQSVPFSATELLLASAIFCLVFWVLKGLRPRVPKGLKSPPEPWGWPLLGHVLTLGKN
PHLALSRMSQRYGDVLQIRIGSTPVLVLSRLDTIRQALVRQGDDFKGRPDLYTSTLITDG
QSLTFSTDSGPVWAARRRLAQNALNTFSIASDPASSSSCYLEEHVSKEAKALISRLQELM
AGPGHFDPYNQVVVSVANVIGAMCFGQHFPESSDEMLSLVKNTHEFVETASSGNPLDFFP
ILRYLPNPALQRFKAFNQRFLWFLQKTVQEHYQDFDKNSVRDITGALFKHSKKGPRASGN
LIPQEKIVNLVNDIFGAGFDTVTTAISWSLMYLVTKPEIQRKIQKELDTVIGRERRPRLS
DRPQLPYLEAFILETFRHSSFLPFTIPHSTTRDTTLNGFYIPKKCCVFVNQWQVNHDPEL
WEDPSEFRPERFLTADGTAINKPLSEKMMLFGMGKRRCIGEVLAKWEIFLFLAILLQQLE
FSVPPGVKVDLTPIYGLTMKHARCEHVQARLRFSIN
NT seq 1551 nt NT seq  +upstreamnt  +downstreamnt
atggcattgtcccagtctgttcccttctcggccacagagcttctcctggcctctgccatc
ttctgcctggtattctgggtgctcaagggtttgaggcctcgggtccccaaaggcctgaaa
agtccaccagagccatggggctggcccttgctcgggcatgtgctgaccctggggaagaac
ccgcacctggcactgtcaaggatgagccagcgctacggggacgtcctgcagatccgcatt
ggctccacgcccgtgctggtgctgagccgcctggacaccatccggcaggccctggtgcgg
cagggcgacgatttcaagggccggcctgacctctacacctccaccctcatcactgatggc
cagagcttgaccttcagcacagactctggaccggtgtgggctgcccgccggcgcctggcc
cagaatgccctcaacaccttctccatcgcctctgacccagcttcctcatcctcctgctac
ctggaggagcatgtgagcaaggaggctaaggccctgatcagcaggttgcaggagctgatg
gcagggcctgggcacttcgacccttacaatcaggtggtggtgtcagtggccaacgtcatt
ggtgccatgtgcttcggacagcacttccctgagagtagcgatgagatgctcagcctcgtg
aagaacactcatgagttcgtggagactgcctcctccgggaaccccctggacttcttcccc
atccttcgctacctgcctaaccctgccctgcagaggttcaaggccttcaaccagaggttc
ctgtggttcctgcagaaaacagtccaggagcactatcaggactttgacaagaacagtgtc
cgggacatcacgggtgccctgttcaagcacagcaagaaggggcctagagccagcggcaac
ctcatcccacaggagaagattgtcaaccttgtcaatgacatctttggagcaggatttgac
acagtcaccacagccatctcctggagcctcatgtaccttgtgaccaagcctgagatacag
aggaagatccagaaggagctggacactgtgattggcagggagcggcggccccggctctct
gacagaccccagctgccctacttggaggccttcatcctggagaccttccgacactcctcc
ttcttgcccttcaccatcccccacagcacaacaagggacacaacgctgaatggcttctac
atccccaagaaatgctgtgtcttcgtaaaccagtggcaggtcaaccatgacccagagctg
tgggaggacccctctgagttccggcctgagcggttcctcaccgccgatggcactgccatt
aacaagcccttgagtgagaagatgatgctgtttggcatgggcaagcgccggtgtatcggg
gaagtcctggccaagtgggagatcttcctcttcctggccatcctgctacagcaactggag
ttcagcgtgccgccgggcgtgaaagtcgacctgacccccatctacgggctgaccatgaag
cacgcccgctgtgaacatgtccaggcgcggctgcgcttctccatcaattga

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