KEGG T01001: 1794

Homo sapiens (human): 1794

Entry

1794 CDS T01001

Gene name

DOCK2

Definition

dedicator of cytokinesis 2

Orthology

K12367

dedicator of cytokinesis 2

Organism

hsa Homo sapiens (human)

Pathway

hsa04062	Chemokine signaling pathway
hsa04666	Fc gamma R-mediated phagocytosis

Class

Organismal Systems; Immune system; Fc gamma R-mediated phagocytosis [PATH:hsa04666]
Organismal Systems; Immune system; Chemokine signaling pathway [PATH:hsa04062]

SSDB

Motif

Pfam:

DOCK-C2 Ded_cyto SH3_2 SH3_9 SH3_1

Other DBs

NCBI-GI:

NCBI-GeneID:

OMIM:

HGNC:

HPRD:

Ensembl:

Vega:

UniProt:

Structure

PDB:

3A98 2YIN 3B13

Position

5q35.1

AA seq 1830 aa
MAPWRKADKERHGVAIYNFQGSGAPQLSLQIGDVVRIQETCGDWYRGYLIKHKMLQGIFP
KSFIHIKEVTVEKRRNTENIIPAEIPLAQEVTTTLWEWGSIWKQLYVASKKERFLQVQSM
MYDLMEWRSQLLSGTLPKDELKELKQKVTSKIDYGNKILELDLIVRDEDGNILDPDNTSV
ISLFHAHEEATDKITERIKEEMSKDQPDYAMYSRISSSPTHSLYVFVRNFVCRIGEDAEL
FMSLYDPNKQTVISENYLVRWGSRGFPKEIEMLNNLKVVFTDLGNKDLNRDKIYLICQIV
RVGKMDLKDTGAKKCTQGLRRPFGVAVMDITDIIKGKAESDEEKQHFIPFHPVTAENDFL
HSLLGKVIASKGDSGGQGLWVTMKMLVGDIIQIRKDYPHLVDRTTVVARKLGFPEIIMPG
DVRNDIYITLLQGDFDKYNKTTQRNVEVIMCVCAEDGKTLPNAICVGAGDKPMNEYRSVV
YYQVKQPRWMETVKVAVPIEDMQRIHLRFMFRHRSSLESKDKGEKNFAMSYVKLMKEDGT
TLHDGFHDLVVLKGDSKKMEDASAYLTLPSYRHHVENKGATLSRSSSSVGGLSVSSRDVF
SISTLVCSTKLTQNVGLLGLLKWRMKPQLLQENLEKLKIVDGEEVVKFLQDTLDALFNIM
MEHSQSDEYDILVFDALIYIIGLIADRKFQHFNTVLEAYIQQHFSATLAYKKLMTVLKTY
LDTSSRGEQCEPILRTLKALEYVFKFIVRSRTLFSQLYEGKEQMEFEESMRRLFESINNL
MKSQYKTTILLQVAALKYIPSVLHDVEMVFDAKLLSQLLYEFYTCIPPVKLQKQKVQSMN
EIVQSNLFKKQECRDILLPVITKELKELLEQKDDMQHQVLERKYCVELLNSILEVLSYQD
AAFTYHHIQEIMVQLLRTVNRTVITMGRDHILISHFVACMTAILNQMGDQHYSFYIETFQ
TSSELVDFLMETFIMFKDLIGKNVYPGDWMAMSMVQNRVFLRAINKFAETMNQKFLEHTN
FEFQLWNNYFHLAVAFITQDSLQLEQFSHAKYNKILNKYGDMRRLIGFSIRDMWYKLGQN
KICFIPGMVGPILEMTLIPEAELRKATIPIFFDMMLCEYQRSGDFKKFENEIILKLDHEV
EGGRGDEQYMQLLESILMECAAEHPTIAKSVENFVNLVKGLLEKLLDYRGVMTDESKDNR
MSCTVNLLNFYKDNNREEMYIRYLYKLRDLHLDCDNYTEAAYTLLLHTWLLKWSDEQCAS
QVMQTGQQHPQTHRQLKETLYETIIGYFDKGKMWEEAISLCKELAEQYEMEIFDYELLSQ
NLIQQAKFYESIMKILRPKPDYFAVGYYGQGFPSFLRNKVFIYRGKEYERREDFQMQLMT
QFPNAEKMNTTSAPGDDVKNAPGQYIQCFTVQPVLDEHPRFKNKPVPDQIINFYKSNYVQ
RFHYSRPVRRGTVDPENEFASMWIERTSFVTAYKLPGILRWFEVVHMSQTTISPLENAIE
TMSTANEKILMMINQYQSDETLPINPLSMLLNGIVDPAVMGGFAKYEKAFFTEEYVRDHP
EDQDKLTHLKDLIAWQIPFLGAGIKIHEKRVSDNLRPFHDRMEECFKNLKMKVEKEYGVR
EMPDFDDRRVGRPRSMLRSYRQMSIISLASMNSDCSTPSKPTSESFDLELASPKTPRVEQ
EEPISPGSTLPEVKLRRSKKRTKRSSVVFADEKAAAESDLKRLSRKHEFMSDTNLSEHAA
IPLKASVLSQMSFASQSMPTIPALALSVAGIPGLDEANTSPRLSQTFLQLSDGDKKTLTR
KKVNQFFKTMLASKSAEEGKQIPDSLSTDL

NT seq 5493 nt +upstreamnt +downstreamnt
atggccccctggcgcaaagctgacaaggagcggcacggcgtggccatatacaacttccaa
ggcagcggagccccccagctctccctgcagatcggcgatgtggtgcgaatacaggagacg
tgtggagactggtataggggatacctcataaagcacaaaatgttacagggcatttttcct
aagtcatttatccacatcaaggaagtgacagttgagaaaagaagaaatactgagaacatc
attcctgcagaaattcctctggcacaagaagtgacaacgacactttgggaatggggaagc
atctggaaacaactctatgtggccagcaaaaaggagcgttttctccaggtgcagtccatg
atgtacgatctgatggagtggaggtcccagcttctctcaggaaccttacccaaggatgag
ctgaaggaactgaagcagaaagtcacgtccaaaattgactatggcaacaaaatccttgag
cttgatttgattgtcagagatgaagacggaaatatcttggaccctgataataccagtgtc
atcagcttgttccatgcacatgaggaagcaactgataaaatcacagagcgtatcaaagaa
gaaatgtcaaaagaccagccagattatgcaatgtattcccggatctcctcatcccccacc
catagcctctatgtgtttgtgagaaactttgtgtgcagaattggggaagatgctgagctc
ttcatgtctctctacgaccccaacaagcaaacggtcataagtgagaactacctagtgcga
tggggcagccggggcttccctaaggagattgagatgctcaacaatctgaaggtggtcttc
acggatcttggaaacaaagacctcaacagggataaaatttacttgatttgtcaaatagtc
cgggtcggcaagatggatcttaaggatactggtgcaaagaagtgcacgcagggactgagg
aggccctttggggtggcagttatggatataacagacatcatcaaggggaaagcagagagt
gatgaagaaaagcagcacttcattccttttcacccggttacagctgagaatgacttccta
cacagcctgctgggcaaagtcatagcctccaagggggacagtggagggcaaggcctctgg
gtgaccatgaagatgctggtgggtgacatcattcagattcgcaaggactatccacacctg
gtggacaggaccaccgtggtggccaggaagctgggattcccagagatcatcatgccaggg
gatgtcaggaacgacatctacattactctcttacaaggtgactttgacaagtacaacaag
accacacagaggaatgtggaagtcatcatgtgtgtgtgcgcggaggatggcaaaacgctg
cctaatgcaatttgcgtgggagcaggggacaagcccatgaatgagtatcgctccgttgtg
tactatcaagtcaaacagccacgctggatggaaacagtcaaggtggctgtccctattgaa
gacatgcagaggatccatctgcgattcatgtttcgacatcggtcatctctggaatctaaa
gataaaggagaaaagaactttgccatgtcctatgtgaagctgatgaaagaagatgggact
actctacacgatggattccatgacttagttgtcctcaagggggacagcaagaagatggag
gatgccagcgcatacctgacccttccttcttatcgacaccatgtggaaaacaagggggcc
acgctgagcaggagctccagcagtgttggggggctttctgtcagctcccgggatgtgttc
tccatttccaccctggtgtgctccacaaagctcactcagaatgtgggcttgctgggtttg
ctgaagtggcgtatgaagcctcaactgctacaggagaatttagaaaagttgaagattgtg
gatggagaggaagtggtgaagtttctccaggatactctggatgccctcttcaacatcatg
atggagcattctcaaagtgatgaatatgacatcctcgtctttgatgccttgatttacata
ataggactcattgcagaccggaaatttcagcatttcaacaccgttctggaggcttacatc
caacagcatttcagtgcgaccttggcttacaagaaattgatgacagtgctgaagacttac
ttggatacctccagcagaggggagcaatgtgagccaatcctaagaacgctgaaggctttg
gaatatgtgttcaagttcattgttcggtcgaggacattattttcacagctttatgaaggc
aaagaacagatggagtttgaagaatccatgagacggctctttgaatccatcaacaatctg
atgaaaagtcaatacaaaactaccatccttttgcaggtggcggctttgaaatacatccca
tctgtcctgcatgatgtagaaatggtctttgatgcgaagttactcagccaactcctgtat
gagttctacacctgcatccctcctgtgaaactccagaagcagaaagtacagtctatgaat
gagatagtccagagcaacctctttaaaaagcaagaatgccgggacattctgcttcctgtc
atcaccaaagagctgaaggagctgctggagcagaaggatgacatgcaacaccaggtcctg
gagaggaagtactgcgttgaattgctcaacagcatcttggaagtccttagctaccaggat
gcggccttcacctaccaccatatccaggagatcatggtccagctgctgcggacagtgaac
cggacagtcatcaccatgggccgggatcacattctgattagtcactttgtggcatgtatg
acagccatcttaaaccagatgggtgaccagcactactccttctacattgagaccttccag
accagctctgaacttgtggacttcttgatggagaccttcatcatgttcaaggacctcatt
ggaaagaacgtgtaccctggagactggatggccatgagcatggttcaaaacagggtcttc
ctgagagctatcaacaagtttgcagaaaccatgaaccagaagttcctagaacacacgaac
tttgagttccagctgtggaacaactattttcatctggcagtggcttttatcacccaggat
tctctgcagctggagcagttctcacacgccaaatacaacaaaatcctgaataagtatggg
gacatgagacggctaattggcttctccatccgtgatatgtggtacaagcttggtcagaac
aaaatctgcttcatcccaggcatggtaggacctatattagagatgacacttatccctgag
gctgagctccggaaagccaccataccaatcttcttcgacatgatgctgtgtgaatatcaa
agaagtggggatttcaaaaagtttgaaaacgaaatcatcctgaagctggaccacgaggta
gaagggggccgaggcgacgagcagtacatgcagctcctggagtcaatcctgatggaatgt
gctgcagagcacccaaccattgccaagtcggtggagaacttcgtgaacctggtcaaaggc
ctcctggagaagctgctggattaccggggtgtgatgacagatgagagcaaagacaaccgc
atgagctgcaccgtgaacctgctgaatttctacaaagataacaacagggaggagatgtac
ataaggtacctgtacaaactccgcgatcttcacctggactgtgacaattacacagaggct
gcctacacgctccttctccacacctggcttctcaagtggtcggatgagcagtgtgcatca
caggtcatgcagacaggccagcagcacccccagacacaccggcagctgaaggagacgctc
tacgagaccatcataggctactttgacaaaggaaagatgtgggaagaggccataagtctg
tgcaaggagctggcggaacagtacgagatggagatctttgactatgagctgctcagccag
aacctgatccagcaggcaaaattctatgaaagcatcatgaaaatcctcaggcccaaacca
gactactttgctgttggatactacggccagggattcccctccttcctgcggaacaaagtg
ttcatctaccgcgggaaggaatatgagcgaagagaagatttccagatgcagctgatgacc
cagttccccaatgcagagaagatgaacaccacctctgccccgggagatgatgtgaagaat
gccccaggccagtatatccagtgcttcactgtccagcctgtcttggatgaacatcccagg
ttcaagaataagccagtgcctgaccagattataaacttctacaaatccaactacgtgcaa
aggttccactactcccggcccgtgcgcagggggaccgtagacccagagaatgagtttgct
tccatgtggattgagagaacctccttcgtgactgcatacaagctgccggggatcctgcgc
tggtttgaggtggtgcacatgtcgcagaccacaattagtcctctggagaatgccatagaa
accatgtccacggccaatgagaagatcctgatgatgataaaccagtaccagagtgatgag
accctccccatcaacccactctccatgctcctgaacgggattgtggaccctgctgtcatg
ggaggcttcgccaagtatgagaaggccttcttcactgaagagtatgtcagggaccaccct
gaggaccaggacaagctgacccacctcaaggacctgattgcatggcagatccccttcttg
ggagctgggattaagatccatgagaaaagggtgtcagataacttgcgacccttccatgac
cggatggaggaatgtttcaagaacctgaaaatgaaggtggagaaggagtacggtgtccga
gagatgcctgactttgacgacaggagagtgggccgtcccaggtctatgctgcgctcatac
agacagatgtccatcatctctctggcttccatgaattctgactgcagcacccccagcaag
cctacctcagagagctttgacctggaattagcatcacccaagacgccgagagtggagcag
gaggaaccgatctccccggggagcaccctgcctgaggtcaagctgcggaggtccaagaag
aggacaaagagaagcagcgtagtttttgcggatgagaaagcagctgcagagtcggacctg
aagcggctttccaggaagcatgagttcatgagtgacaccaacctctcggagcatgcggcc
atccccctcaaggcgtctgtcctctctcaaatgagctttgccagccagtccatgcctacc
atcccagccctggcgctctcagtggcaggcatccctgggttggatgaggccaacacatct
ccccgcctcagccagaccttcctccaactctcagatggtgacaagaagacactcacacgg
aagaaggtcaatcagttcttcaagacaatgctggccagcaaatcggctgaagaaggcaaa
cagatcccagactcgctgtccacggacctgtga

All links

Pathway (2)   
   KEGG PATHWAY (2)   
Disease (1)   
   OMIM (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (17)   
   KEGG ORTHOLOGY (1)   
   NCBI-Gene (1)   
   NCBI-GI (9)   
   UniGene (1)   
   HGNC (1)   
   HPRD (1)   
   ENSEMBL-HSA (1)   
   OC (1)   
   VEGA (1)   
Protein sequence (3)   
   UniProt (2)   
   RefSeq(pep) (1)   
DNA sequence (25)   
   RefSeq(nuc) (1)   
   GenBank (12)   
   EMBL (12)   
3D Structure (3)   
   PDB (3)   
Protein domain (5)   
   Pfam (5)   
All databases (57)   

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