KEGG   Homo sapiens (human): 1962Help
Entry
1962              CDS       T01001                                 

Gene name
EHHADH, ECHD, FRTS3, L-PBE, LBFP, LBP, PBFE
Definition
enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase (EC:1.1.1.35 5.3.3.8 4.2.1.17)
Orthology
K07514  
enoyl-CoA hydratase / 3-hydroxyacyl-CoA dehydrogenase / 3,2-trans-enoyl-CoA isomerase [EC:4.2.1.17 1.1.1.35 5.3.3.8]
Organism
hsa  Homo sapiens (human)
Pathway
Fatty acid degradation
Valine, leucine and isoleucine degradation
Lysine degradation
Tryptophan metabolism
beta-Alanine metabolism
Propanoate metabolism
Butanoate metabolism
Metabolic pathways
Carbon metabolism
Fatty acid metabolism
PPAR signaling pathway
Peroxisome
Module
Malonate semialdehyde pathway, propanoyl-CoA => Acetyl-CoA
Lysine degradation, lysine => saccharopine => acetoacetyl-CoA
beta-Oxidation
Brite
KEGG Orthology (KO) [BR:hsa00001]
 Metabolism
  Overview
   01200 Carbon metabolism
    1962 (EHHADH)
   01212 Fatty acid metabolism
    1962 (EHHADH)
  Carbohydrate metabolism
   00640 Propanoate metabolism
    1962 (EHHADH)
   00650 Butanoate metabolism
    1962 (EHHADH)
  Lipid metabolism
   00071 Fatty acid degradation
    1962 (EHHADH)
  Amino acid metabolism
   00280 Valine, leucine and isoleucine degradation
    1962 (EHHADH)
   00310 Lysine degradation
    1962 (EHHADH)
   00380 Tryptophan metabolism
    1962 (EHHADH)
  Metabolism of other amino acids
   00410 beta-Alanine metabolism
    1962 (EHHADH)
 Cellular Processes
  Transport and catabolism
   04146 Peroxisome
    1962 (EHHADH)
 Organismal Systems
  Endocrine system
   03320 PPAR signaling pathway
    1962 (EHHADH)
Enzymes [BR:hsa01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.35  3-hydroxyacyl-CoA dehydrogenase
     1962 (EHHADH)
 4. Lyases
  4.2  Carbon-oxygen lyases
   4.2.1  Hydro-lyases
    4.2.1.17  enoyl-CoA hydratase
     1962 (EHHADH)
 5. Isomerases
  5.3  Intramolecular oxidoreductases
   5.3.3  Transposing C=C bonds
    5.3.3.8  dodecenoyl-CoA isomerase
     1962 (EHHADH)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
OMIM: 
HGNC: 
HPRD: 
Ensembl: 
Vega: 
UniProt: 
Position
3q26.3-q28
AA seq 627 aa AA seqDB search
MAFGGGLELALGCHYRIAHAEAQVGLPEVTLGLLPGARGTQLLPRLTGVPAALDLITSGR
RILADEALKLGILDKVVNSDPVEEAIRFAQRVSDQPLESRRLCNKPIQSLPNMDSIFSEA
LLKMRRQHPGCLAQEACVRAVQAAVQYPYEVGIKKEEELFLYLLQSGQARALQYAFFAER
KANKWSTPSGASWKTASARPVSSVGVVGLGTMGRGIVISFARARIPVIAVDSDKNQLATA
NKMITSVLEKEASKMQQSGHPWSGPKPRLTSSVKELGGVDLVIEAVFEEMSLKKQVFAEL
SAVCKPEAFLCTNTSALDVDEIASSTDRPHLVIGTHFFSPAHVMKLLEVIPSQYSSPTTI
ATVMNLSKKIKKIGVVVGNCFGFVGNRMLNPYYNQAYFLLEEGSKPEEVDQVLEEFGFKM
GPFRVSDLAGLDVGWKSRKGQGLTGPTLLPGTPARKRGNRRYCPIPDVLCELGRFGQKTG
KGWYQYDKPLGRIHKPDPWLSKFLSRYRKTHHIEPRTISQDEILERCLYSLINEAFRILG
EGIAASPEHIDVVYLHGYGWPRHKGGPMFYASTVGLPTVLEKLQKYYRQNPDIPQLEPSD
YLKKLASQGNPPLKEWQSLAGSPSSKL
NT seq 1884 nt NT seq  +upstreamnt  +downstreamnt
atggctttcggagggggactagagctggccctgggctgtcactataggattgcccacgca
gaggctcaagttggcttaccagaagttacactgggacttctccctggtgcaagaggaacc
cagcttctccccagactcactggagttcctgctgcacttgacttaattacctcaggaaga
cgtattttagcagatgaagcactcaagctgggcattctagataaagttgtaaactcagac
ccggttgaagaagcaatcagatttgctcagagagtttcagatcaacctctagaatcccgt
agactctgcaacaagccaattcagagcttgcccaacatggacagcatttttagtgaggcc
ctcttgaagatgcggaggcagcaccctgggtgtcttgcacaggaggcttgtgtccgtgca
gtccaggctgctgtgcagtatccctatgaagtgggcatcaagaaggaggaggagctgttt
ctatatcttttgcaatcagggcaggctagagccctgcaatatgctttcttcgctgaaagg
aaagcaaataagtggtcaactccctccggagcatcgtggaaaacagcatcagcgcggcct
gtctcctcagttggtgttgttggcttgggaacaatgggccgaggcattgtcatttctttt
gcaagggccaggattcctgtgattgctgtagactcggacaaaaaccagctagcaactgca
aacaagatgataacctctgtcttggaaaaagaagcctccaaaatgcaacagagcggccac
ccttggtcaggaccaaaacccaggttaacttcatctgtgaaggagcttggtggtgtagat
ttagtcattgaagcagtatttgaggaaatgagcctgaagaagcaggtctttgctgaactc
tcagctgtgtgcaaaccagaagcatttttgtgcactaatacttcagccctggatgttgat
gagattgcttcttccactgatcgtcctcacttggtcattggcacccacttcttttcgcca
gctcatgtcatgaagttgttagaggttattcccagccaatactcttcccccactaccatt
gccactgttatgaacttatcaaaaaagattaaaaagattggagtcgttgtaggcaactgt
tttggatttgtggggaatcgaatgttgaatccttactacaatcaggcatatttcttgtta
gaagaaggcagcaaaccagaggaggtagatcaggtgctggaagagtttggttttaaaatg
ggaccttttagagtgtctgatcttgctgggttggatgtgggctggaaatctagaaagggg
caaggtcttactggacctacattgcttccaggaactcctgcccgaaaaaggggtaatagg
aggtactgcccaattcctgatgtgctctgtgaattaggacgatttggccagaagacaggt
aagggttggtatcaatatgacaagccattgggtaggattcacaaacctgatccctggctt
tccaaattcctatcacggtatagaaaaacccatcacattgaaccacgtaccattagccag
gatgagatccttgaacgctgcttatattcacttatcaatgaagcattccgtatcttggga
gaagggatagctgctagcccagagcacattgatgttgtctatttacatggatatggatgg
ccaaggcacaagggcgggcccatgttctatgcttccacagttgggttgcccacagttcta
gagaaattgcagaaatattacaggcagaaccctgatattccccaactggagccaagtgac
tatctaaaaaaactggcttctcagggaaaccctcccctgaaagaatggcaaagcttggca
ggctcccctagcagtaaattgtga

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