KEGG   Homo sapiens (human): 1977Help
Entry
1977              CDS       T01001                                 

Gene name
EIF4E, AUTS19, CBP, EIF4E1, EIF4EL1, EIF4F, eIF-4E
Definition
(RefSeq) eukaryotic translation initiation factor 4E
  KO
K03259  
translation initiation factor 4E
Organism
hsa  Homo sapiens (human)
Pathway
RNA transport
HIF-1 signaling pathway
mTOR signaling pathway
PI3K-Akt signaling pathway
Longevity regulating pathway
Insulin signaling pathway
Module
eIF4F complex
Drug target
Other: 
Brite
KEGG Orthology (KO) [BR:hsa00001]
 Genetic Information Processing
  Translation
   03013 RNA transport
    1977 (EIF4E)
 Environmental Information Processing
  Signal transduction
   04066 HIF-1 signaling pathway
    1977 (EIF4E)
   04151 PI3K-Akt signaling pathway
    1977 (EIF4E)
   04150 mTOR signaling pathway
    1977 (EIF4E)
 Organismal Systems
  Endocrine system
   04910 Insulin signaling pathway
    1977 (EIF4E)
  Aging
   04211 Longevity regulating pathway - mammal
    1977 (EIF4E)
Messenger RNA biogenesis [BR:hsa03019]
 Eukaryotic Type
  mRNA surveillance and transport factors
   Transport factors
    eIF4F and regulatory proteins
     1977 (EIF4E)
   mRNA cycle factors
    Common to processing body (P body) and stress granule
     1977 (EIF4E)
Translation factors [BR:hsa03012]
 Eukaryotic Type
  Initiation factors
   eIF-4
    1977 (EIF4E)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: 
Motif
Other DBs
NCBI-ProteinID: 
NCBI-GeneID: 
OMIM: 
HGNC: 
HPRD: 
UniProt: 
Structure
PDB: 

Jmol
Position
4q23
AA seq 217 aa AA seqDB search
MATVEPETTPTPNPPTTEEEKTESNQEVANPEHYIKHPLQNRWALWFFKNDKSKTWQANL
RLISKFDTVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQ
QRRSDLDRFWLETLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENREAVTHIG
RVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFVV
NT seq 654 nt NT seq  +upstreamnt  +downstreamnt
atggcgactgtcgaaccggaaaccacccctactcctaatcccccgactacagaagaggag
aaaacggaatctaatcaggaggttgctaacccagaacactatattaaacatcccctacag
aacagatgggcactctggttttttaaaaatgataaaagcaaaacttggcaagcaaacctg
cggctgatctccaagtttgatactgttgaagacttttgggctctgtacaaccatatccag
ttgtctagtaatttaatgcctggctgtgactactcactttttaaggatggtattgagcct
atgtgggaagatgagaaaaacaaacggggaggacgatggctaattacattgaacaaacag
cagagacgaagtgacctcgatcgcttttggctagagacacttctgtgccttattggagaa
tcttttgatgactacagtgatgatgtatgtggcgctgttgttaatgttagagctaaaggt
gataagatagcaatatggactactgaatgtgaaaacagagaagctgttacacatataggg
agggtatacaaggaaaggttaggacttcctccaaagatagtgattggttatcagtcccac
gcagacacagctactaagagcggctccaccactaaaaataggtttgttgtttaa

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